基本信息
李壮 男 汉族 博导 长春应用化学研究所
电子邮件:zli@ciac.jl.cn
联系电话:0431-85262057
手机号码:
通信地址:长春市人民大街5625号
邮政编码:130022

研究领域

扫描探针显微学及电化学,DNA/蛋白质结构及相互作用,纳米器件及表面增强拉曼散射光谱研究

教育背景

   
学历
1991年,中国科学院长春应用化学研究所,分析化学专业, 理学博士
1987年,中国科学院长春应用化学研究所,高分子化学专业,理学硕士
1983年,延安大学,理学学士
学位
中国科学院长春应用化学研究所 理学博士
出国学习工作

1993-1995年,德国Jena分子生物技术研究所分子细胞和电子显微学实验室,客座科学家

工作经历

   
工作简历
1983-1984年,陕西省榆林地区教研室,教学研究员
1991-1993年,吉林大学光化学研究室,博士后
1995-1998年,长春应用化学研究所电分析化学开放实验室,副研究员
1998年-至今,长春应用化学研究所电分析国家重点实验室副主任,研究员,博士生导师。中国科学院研究生院教授。

教授课程

扫描探针显微学

专利与奖励

   
奖励信息

获中国科学院自然科学三等奖一次。
2003年吉林省科学进步一等奖(扫描探针显微技术在电化学和生命科学中的研究基础,排名第三)。
2004年吉林省科学技术进步一等奖(功能化电极界面的研究——从化学修饰到自组装,排名第五)。

专利成果
(1) 地下水节水灌溉管的制备方法,发明,专利号:98125656
(2) 扫描探针显微镜样品定位方法,发明,专利号:99126338
(3) 可控纳米导线的机械制备方法,发明,专利号:01110205
(4) 原子力显微镜可调多探针针座,发明,专利号:01224491
(5) 原子力显微镜探针针座,发明,专利号:99256948
(6) 汉语偏旁部首首字母输入法,发明,专利号:00104585
(7) 可控金属纳米导线的化学制备方法,发明,专利号:01140159
(8) 纳米荧光斑超高密度信息存取方法,发明,专利号:01118255
(9) 可控纳米导线的物理化学制备方法,发明,专利号:01110206
(10) 原子力显微镜多探针针座,发明,专利号:01204082
(11) 水平动力分子梳,发明,专利号:02104270
(12) 可控脱氧核糖核酸网络的制作方法,发明,专利号:02104271
(13) 取代显微镜暗室或暗箱操作的新方法,发明,专利号:10115941
(14) 原子力显微镜研究DNA所用样品的制备方法,发明,专利号:10016720
(15) 一种用于扫描探针显微镜的金薄膜基底的制作方法,发明,专利号:10011064
(16) 制作应用于原子力显微镜研究的具有定位功能的基底,发明,专利号:10011339
(17) 一种三聚氰胺的检测方法,发明,2011,第1作者,专利号:201110068576.8
(18) 一种用于表面增强拉曼散射的基底及其制备方法,发明,2011,第1作者,专利号:201110068574.9
(19) 空心金纳米笼的一种新型制备方法,发明,2010,第1作者,专利号:2010101020131

出版信息

   
发表论文
(1) Assembly of Ni(OH)2 nanoplates on graphene: a two dimensional nanocomposite for enzymefree glucose sensing,J. Mater. Chem.,2011,通讯作者
(2) Silver Nanoparticles Coated Zinc Oxide Nanorods Array as Superhydrophobic Substrate for the Amplified SERS Effect,J. Phys. Chem. C,2011,通讯作者
(3) DNA adsorption and desorption on mica surface studied by atomic force microscopy,Appl. Surf. Sci.,2011,通讯作者
(4) Formation of Gold Nanoparticle Decorated Lysozyme Microtubes,Biomacromolecules,2011,通讯作者
(5) Au nanocages for highly sensitive and selective detection of H2O2,J. Electroanal. Chem.,2011,通讯作者
(6) Carbon nanotube decorated with silver nanoparticles via noncovalent interaction for a novel nonenzymatic sensor towards hydrogen peroxide reduction,J. Electroanal. Chem.,2011,通讯作者
(7) Interaction between DNA and Microcystin-LR Studied by Spectra Analysis and Atomic Force Microscopy,Biomacromolecules,2011,通讯作者
(8) Facile Synthesis of Urchin-Like Gold Submicrostructures for Nonenzymatic Glucose Sensing,Talanta,2010,通讯作者
(9) Seed-Mediated Synthesis of Au Nanocages and Their Electrocatalytic Activity towards Glucose Oxidation,Chem-Eur. J.,2010,通讯作者
(10) Facile fabrication of single crystal gold nanoplates with micrometer lateral size,Colloid Surf. A-Physicochem. Eng. Asp.,2010,通讯作者
(11) Seed-Mediated Synthesis of Au Nanocages and Their Electrocatalytic Activity towards Glucose Oxidation,Chem-Eur. J.,2010,通讯作者
(12) Novel nonenzymatic hydrogen peroxide sensor based on iron oxide-silver hybrid submicrospheres,Talanta ,2010,通讯作者
(13) Carbon nanotube/raspberry hollow Pd nanosphere hybrids for methanol, ethanol, and formic acid electro-oxidation in alkaline media,J. Colloid. Interf. Sci. ,2010,通讯作者
(14) Type I collagen-mediated synthesis of noble metallic nanoparticles networks and the applications in ,Talanta,2009,通讯作者
(15) Influence of Polyelectrolyte on DNA-RecA Nucleoprotein Filaments: Poly-L-Lysine Used as a Model,ChemPhysChem,2009,通讯作者
(16) Surface Relevant Regulable DNA Toroids Induced by Dopamine,J. Phys. Chem. B,2009,通讯作者
(17) Electrodeposition of Platinum Nanoclusters on Type I Collagen Modified Electrode and its Electrocata,Appl. Surf. Sci.,2009,通讯作者
(18) Novel Hybrid Electrocatalyst with Enhanced Performance in Alkaline Media: Hollow Au/Pd Core/Shell Nanostructures with a Raspberry Surface,J. Phys. Chem. C,2009,通讯作者
(19) Type I collagen-templated assembly of silvernanoparticles and their application in surface-enhanced ,Nanotechnology,2008,通讯作者
(20) Controllable synthesis of gold nanowires,Mater. Lett.,2008,通讯作者
(21) Photochemical synthesis and self-assembly of gold nanoparticles,Colloids and Surfaces A: Physicochem. Eng. Aspects,2008,通讯作者
(22) Aggregation-based growth of silver nanowires at room temperature,Appl. Surf. Sci,2008,通讯作者
(23) Self-assembly of λ-DNA networks/Ag nanoparticles: Hybrid architecture, and active-SERS substrate,J. Colloid Interface Sci.,2008,通讯作者
(24) DNA-Templated Gold Nanoparticles Formation,J. Nanosci. Nanotechno.,2008,通讯作者
(25) Ethanol-Induced Formation of Silver Nanoparticle Aggregates for Highly Active SERS Substrates and Ap,J. Phys. Chem. C,2008,通讯作者
(26) Atomic Force Microscopic Study of Low Temperature Induced Disassembly of RecA-dsDNA Filaments,J. Phys. Chem. B,2008,通讯作者
(27) Fabrication, characterization, and application in surface-enhanced Raman spectrum of assembled type-,J. Chem. Phys. ,2008,通讯作者
(28) Electrostatic assembly of protein lysozyme on DNA visualized by atomic force microscopy,Appl. Surf. Sci.,2007,通讯作者
(29) Room temperature ionic liquid doped DNA network immobilized horseradish peroxidase biosensor for amp,Anal. Bioanal. Chem.,2007,通讯作者
(30) Controlled organization of silver nanoparticles into network assemblies by tuning pH values,Chem. Lett.,2007,通讯作者
(31) Large-scale, uniform DNA network on 11-mercaptoundecanoic acid modified gold (111) surface: Atomic f,Microsc. Res. Tech.,2007,通讯作者
(32) Self-assembled gold nanoparticle chains in presence of silver ions,Chem. Lett.,2007,通讯作者
(33) Effects of bridge ions, DNA species, and developing temperature on flat-lying DNA monolayers, J. Phys. Chem. B,2007,通讯作者
(34) Synthesis, characterization, and self-assembly of protein lysozyme monolayer-stabilized gold nanopar,Langmuir,2007,通讯作者
(35) Type I Collagen-Mediated Synthesis and Assembly of UV-Photoreduced Gold Nanoparticles and Their Appl,J. Phys. Chem. C,2007,通讯作者
(36) Electrostatic assembly of Cu2O nanoparticles on DNA templates,Appl. Surf. Sci.,2006,通讯作者
(37) Fabrication of silver nanoparticles ring template by plasmid DNA,Appl. Surf. Sci.,2006,通讯作者
(38) Manipulation, dissection, and lithography using modified tapping mode atomic force microscope,Microsc. Res. Tech.,2006,通讯作者
(39) Diluting thiol-derivatized oligonucleotide monolayers on Au(111) by mercaptohexanol replacement reac,Appl. Surf. Sci.,2006,通讯作者
(40) Solution-phase synthesis of Au@ZnO core-shell composites,Mater. Lett.,2006,通讯作者
(41) Hydrogen peroxide sensor based on horseradish peroxidase immobilized on a silver nanoparticles/cyste,Anal. Bioanal. Chem.,2006,通讯作者
(42) A novel hydrogen peroxide sensor based on horseradish peroxidase immobilized in DNA films on a gold ,Sens. Actuators, B,2006,通讯作者
(43) A novel strategy to construct a flat-lying DNA monolayer on a mica surface,J. Phys. Chem. B,2006,通讯作者
(44) Self-assembly of cinnamic acid-capped gold nanoparticles,Nanotechnology,2006,通讯作者
(45) Fabrication of linear aniline-DNA complex nanowires and DNA-templated polyaniline nanowires,Chem. J. Chin. Univ.-Chin.,2006,通讯作者
(46) Observation of the mica surface by atomic force microscopy,Micron,2005,通讯作者
(47) Immobilization and condensation of DNA with 3-aminopropyltriethoxysilane studied by atomic force mic,Journal of Microscopy-Oxford,2005,通讯作者
(48) Nanoscale structures of circle-MgCl2 constructed by plasmid DNA templates,Superlattices Microstruct.,2005,通讯作者
(49) A simple method for the preparation of ultrahigh sensitivity surface enhanced Raman scattering (SERS,Appl. Surf. Sci.,2005,通讯作者
(50) Electrostatic assembly of CTAB-capped silver nanoparticles along predefined λ-DNA template,Appl. Surf. Sci.,2005,通讯作者
(51) DNA-network-templated self-assembly of silver nanoparticles and their application in surface-enhance,J. Phys. Chem. B,2005,通讯作者
(52) Covalent assembly of shortened multiwall carbon nanotubes on polyelectrolyte films and relevant elec,J. Colloid. Interface. Sci.,2005,通讯作者
(53) Immobilization of DNA on 11-mercaptoundecanoic acid-modified gold(111) surface for atomic force micr,Microsc. Res. Tech.,2005,通讯作者
(54) Imaging DNA molecules on mica surface by atomic force microscopy in air and in liquid,Microsc. Res. Tech.,2005,通讯作者
(55) Mechanically engraved mica surface using the atomic force microscope tip facilitates return to a spe,Microsc. Res. Tech.,2005,通讯作者
(56) Synthesis of nanowires, nanorods and nanoparticles of ZnO through modulating the ratio of water to m,Mater. Chem. Phys.,2005,通讯作者
(57) One-step synthesis of silver nanoparticles, nanorods, and nanowires on the surface of DNA network,J. Phys. Chem. B,2005,通讯作者
(58) Direct patterning of rhodamine 6G molecules on mica by dip-pen nanolithography,Appl. Surf. Sci.,2004,通讯作者
(59) DNA network structures on various solid substrates investigated by atomic force microscopy,Anal. Sci.,2004,通讯作者
(60) Atomic force microscope investigation of large-circle DNA molecules,Anal. Biochem. ,2004,通讯作者
(61) The influence of tip performance on scanning probe lithography,Appl. Surf. Sci.,2004,通讯作者
发表著作
(1) ,Interfacial Protein Science: Methods and Applications in Biotechnology and Materials Science. PART II: Applications. Chapter: The preparation of nanomaterials based on peptides and proteins and their applications.,John Wiley and Sons, Inc.,2011-10,第2作者
(2) ,Mica: Properties, Synthesis and Applications. Chapter: Mica, a main substrate of Atomic Force Microscope for biological and nanotechnological research.,Nova Science Publishers, Inc.,2011-08,第2作者
(3) ,Biomedical Engineering - Frontiers and Challenges. Chapter: Formation of Gold Nanoparticle Decorated Lysozyme Microtubes,InTech - Open Access Publisher,2011-08,第1作者
(4) 《生命分析化学》第十九章 扫描探针显微镜,科学出版社,2006-07
(5) 《现代高分子物理学》第十五章 原子力显微镜,科学出版社,2003-04

科研活动

   
科研项目
(1) 纳米材料与纳米技术在水污染检测与治理中的应用基础研究,主持,国家级,2010-01--2014-12
(2) 脑中化学信息物质的时间分辨分析,主持,院级级,2008-01--2010-12
(3) 可控纳米线的制备及表面增强拉曼散射研究,主持,国家级,2008-01--2010-12
参与会议
(1) 第九届国际电分析化学研讨会,
(2) 中国遗传学会基因组学委员会第一次会议暨基因组研究会,
(3) 第九届国际电分析化学研讨会,
(4) 第十一届国际暨第一届中日双边电分析化学会议,
(5) 第十四届全国光散射学术会议,
(6) 第八届全国电分析化学学术会议,
(7) 中国蛋白质组学第三届学术大会,
(8) 第十届国际电分析化学研讨会暨第三届中—法生物相关分子表面电化,
(9) A Novel Superhydrophobic Substrate for Surface Enhanced Raman Scattering,No,2011-05,Zhuang Li
(10) Construction of Controllable Nanowires by SPM Nanomanipulation,No,2011-05,Zhuang Li

指导学生

孙玉静  博士研究生  070302-分析化学  80037-长春应用化学研究所

郭存兰  博士研究生  070302-分析化学  80037-长春应用化学研究所

刘哲林  博士研究生  070302-分析化学  80037-长春应用化学研究所

张悦  硕士研究生  070302-分析化学  80037-长春应用化学研究所

石岩  硕士研究生  070302-分析化学  80037-长春应用化学研究所

许富刚  博士研究生  070302-分析化学  80037-长春应用化学研究所

温志伟  硕士研究生  070302-分析化学  80037-长春应用化学研究所