1  基于先进材料（纳米材料，多孔材料等）的分子识别、检测及手性分离；
2  金属离子、有机小分子与DNA、蛋白质相互作用

   

070302-分析化学

有机分析及生物分析
手性化合物的分离识别

2003-06--2006-06   中国科学院大学   博士后
1999-09--2002-06   中国科学院研究生院   博士
1996-09--1999-06   山西大学   硕士
1987-09--1991-07   兰州大学   本科

中科院研究生院 -- 研究生

中科院研究生院 -- 博士

美国加州州立大学访问学者，2008

   

2002-06~现在, 中国科学院大学, 教师
1991-08~1996-08,山西原平化工厂, 助理工程师

2023-01-01-2026-12-31,中国化学会有机分析专业委员会, 委员
2018-04-23-今,分析试验室编委, 编委

   

1  Sen Yang, Xiangjun Li*. Vibrational circular dichroism study and gas chromatographic analysis of chiral epichlorohydrin. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 303 (2023) 123237

2   Shaokun Chen , Weiyi Lai, Yanan Li , Yan Liu, Jie Jiang, Xiangjun Li,* , Guibin Jiang, Hailin Wang,**. Aberrant DNA N6-methyladenine incorporation via adenylate kinase 1 is suppressed by ADAL deaminase-dependent 20-deoxynucleotide pool sanitation, The EMBO Journal e113684 | 2023

3  Lixia Chen, Tingting Tian, Sen Yang, Yalei Dong, Hong Cui, Xiangjun Li*. Separation and identification of cetirizine enantiomers in human urine by CE, J Sep Sci 2023;2200901

4   Lixia Chen , Xiangjun Li*, Tingting Tian, Sen Yang, Huiqun WangEnantioseparation and mechanism study on baclofen by capillary electrophoresis and molecular modeling, Journal of Pharmaceutical and Biomedical Analysis 229 (2023) 115371

5  Shao-Kun CHEN , Xiang-Jun LI∗. Quantification of epigenetic DNA modifications of subchromatin structures by UHPLC-MS/MS. Chinese Journal of Analytical Chemistry 50.6 (2022) 100093

6   Shaokun Chen, Weiyi Lai, Xiangjun Li,* and Hailin Wang*. Necrosulfonamide Selectively Induces DNA Double-Strand Breaks in Acute Myeloid Leukemia Cells. Chem. Res. Toxicol. 2022, 35, 387−391

7   Dao Lin, Yuhe Kan, Liang Yan, Yongqi Ke, Yang Zhang, Hang Luo, Xinjing Tang, Xiangjun Li,* Yujian He,* and Li Wu,* Redox manipulation of enzyme activity through physiologically active molecule. iScience 24, 102977, September 24, 2021 https://doi.org/10.1016 /j.isci.2021.102977

8   Mingxia Liu, Lixia Chen, Xiangjun Li, JinghuaMeng, Yu Bai, Huwei Liu. Separation and determination of 3-hydroxyaspartate by online concentration capillary electrophoresis/laser induced fluorescence with microwave-assisted derivatization. J Sep Sci 2021;44:3646–3653.

9   Lixia Chen, Mingxia Liu, Sen Yang, Hong Zhao, Xin Yao , Xiangjun Li∗, Jinghua Meng. Theoretical electronic circular dichroism investigations of chiral amino acids and development of separation and identification methods independent of standards. Journal of Chromatography A 1654 (2021) 462446

10 Yangde Ma, Ning Zhang, Shaokun Chen, Jingwei Sun, Yan Liu, Xiangjun Li*, Hailin Wang. One-pot intramolecular cyclization of 5-hydroxymethylcytosine for sequencing DNA hydroxymethylation at single-base resolution. Analyst，2021, 146, 820.

11   Qingju Liu, Yongqi Ke, Yuhe Kan, Xinjing Tang, Xiangjun Li*, Yujian He*, Li Wu*, Compatibility and Fidelity of Mirror-Image Thymidine in Transcription Events by T7 RNA Polymerase. Molecular Therapy: Nucleic Acids ,2020, 21,604-613

12   Tingting Tian, Mingxia Liu, Lixia Chen, Fengjiao Zhang, Xin Yao, Hong Zhao, Xiangjun Li*, D-amino Acid Electrochemical Biosensor Based on D-amino Acid Oxidase: Mechanism and High Performance against Enantiomer Interference, Biosensors and Bioelectronics, 151 (2020) 111971-7

13  Mingxia Liu, Lixia Chen, Tingting Tian, Zhiguo Zhang, Xiangjun Li*. Identification and Quantitation of Enantiomers by Capillary Electrophoresis and Circular Dichroism Independent of Single Enantiomer Standard，Analytical Chemistry，2019, 91, 21, 13803-13809

14   Zhong, Shangwei; Li, Cuiping; Han, Xiao; Li, Xiangjun; Yang, Yungui; Wang, Hailin. Idarubicin stimulates cell cycle- and TET2-dependent oxidation of DNA 5-methylcytosine in cancer cells. Chemical Research in Toxicology, 2019, 32, 861−868

15  Mingxia Liu, Hong Zhao, Zhiguo Zhang, Xiangjun Li*, Lanqun Mao,Ruiping Zhang, Yuekui Wang. Derivatization reagent-assisted enantioseparation of 3-hydroxyaspartate with two chiral centers in rat cerebrospinalfluid by capillary electrophoresis-mass spectrometry. Analytica Chimica Acta，1047 (2019) 257-266

   

（1） 高速发展的中国化学//有机分析, *, 科学出版社, 2012-04, 第 3 作者