李伟  男  研究员、博导  中国科学院动物研究所
电子邮件: liwei@ioz.ac.cn
通信地址: 北京市朝阳区大屯路甲3号院 中国科学院干细胞与再生医学创新研究院
邮政编码: 100101

研究领域

基因组信息及其表达调控是生命多样性和复杂性的重要基础,也是疾病治疗和健康干预的重要靶标和手段。我们特别感兴趣结合基因工程、细胞工程和合成生物学等手段建立新的基因工程技术和细胞/动物模型,用于(1)揭示生殖与再生相关性状及其种间进化差异的调控机制;(2)设计和制造功能定制化的细胞;(3)重大疾病的基因治疗。

招生信息

   
招生专业
1001J6-再生医学
招生方向
干细胞,基因工程

教育背景

2006-09--2013-01   中国科学院大学/中国科学院动物研究所   理学博士
2002-09--2006-06   武汉大学   学士
学历
研究生

学位
博士

工作经历

   
工作简历
2017-09~现在, 中国科学院动物研究所干细胞与生殖生物学国家重点实验室, 副主任
2016-01~现在, 中国科学院动物研究所, 研究员
2013-02~2015-12,中国科学院动物研究所, 星辰研究员
社会兼职
2020-01-01-今,发展中国家科学院(TWAS), 青年会士
2019-10-10-今,中国医药生物技术协会基因编辑技术分会, 常务委员
2019-10-01-今,中国动物学会生殖生物学分会, 副主任委员
2019-05-01-今,中国实验动物学会灵长类实验动物专业委员会, 常务委员
2018-05-01-今,中国细胞生物学学会衰老细胞生物学分会, 委员
2014-01-01-今,中国科学院青年创新促进会, 会员
2013-09-01-今,中国遗传学会青年委员会, 委员

教授课程

干细胞生物学
现代生殖医学之生理基础
胚胎工程
干细胞前沿技术
生殖生理学
干细胞研究进展系列讲座

专利与奖励

   
奖励信息
(1) 中国细胞生物学学会干细胞生物学分会干细胞研究创新奖, 其他, 2020
(2) 中国科学院杰出科技成就奖, , 院级, 2020
(3) 中国科学院青年科学家奖, , 院级, 2018
(4) 第十二届中国科学院杰出青年, , 院级, 2017
(5) 中源协和生命医学创新突破奖, , 其他, 2016
(6) 卢嘉锡青年人才奖, 院级, 2015
(7) 中国科学院杰出科技成就奖, , 院级, 2013
(8) 日本实验动物学会国际奖, , 其他, 2013

出版信息

   
发表论文
[1] Xuehan Sun, Chen Liang, Yangcan Chen, Tongtong Cui, Jiabao Han, Moyu Dai, Ying Zhang, Qi Zhou, Wei Li. Knockout and replacement gene surgery to treat rhodopsin-mediated autosomal dominant retinitis pigmentosa. Human Gene Therapy[J]. 2024, 35(5-6): 151-162, 
[2] Dai, Moyu, Yang, Ning, Xu, Kai, Zhang, Jingwen, Li, Xueke, Zhang, Ying, Li, Wei. Discovering human cell-compatible gene therapy virus variants via optimized screening in mouse models. CELL PROLIFERATION[J]. 2024, 57(3): e13565, http://dx.doi.org/10.1111/cpr.13565.
[3] Fei Teng, Tongtong Cui, Li Zhou, Qingqin Gao, Qi Zhou, Wei Li. Programmable synthetic receptors: the next-generation of cell and gene therapies. SIGNAL TRANSDUCTION AND TARGETED THERAPY[J]. 2024, 9(1): 1-25, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761793/.
[4] Dainan Yu, Haifeng Wan, Chao Tong, Lu Guang, Gang Chen, Jiali Su, Lan Zhang, Yue Wang, Zhenyu Xiao, Jinglei Zhai, Long Yan, Wenwu Ma, Kun Liang, Taoyan Liu, Yuefan Wang, Zehang Peng, Lanfang Luo, Ruoxuan Yu, Wei Li, Hongbo Qi, Hongmei Wang, Ng ShyhChang. A multi-tissue metabolome atlas of primate pregnancy. CELL[J]. 2024, 187(3): 764-781.e14, http://dx.doi.org/10.1016/j.cell.2023.11.043.
[5] Jinglei Zhai, Yanhong Xu, Haifeng Wan, Rui Yan, Jing Guo, Robin Skory, Long Yan, Xulun Wu, Fengyuan Sun, Gang Chen, Wentao Zhao, Kunyuan Yu, Wei Li, Fan Guo, Nicolas Plachta, Hongmei Wang. Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture. CELL[J]. 2023, 186(10): 2078-2091.e18, http://dx.doi.org/10.1016/j.cell.2023.04.019.
[6] Wenliang Zhu, Mengqi Li, Jun Zou, Da Zhang, Minghui Fang, Yun Sun, Can Li, Mingming Tang, Yukai Wang, Qi Zhou, Tongbiao Zhao, Wei Li, Zheng Hu, Baoyang Hu. Induction of local immunosuppression in allogeneic cell transplantation by cell-type-specific expression of PD-L1 and CTLA4Ig. STEM CELL REPORTS[J]. 2023, 18(12): 2344-2355, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10724073/.
[7] Juan Yu, Nianye Yu, Yao Tian, Yifan Fang, Bin An, Guihai Feng, Jun Wu, Liu Wang, Jie Hao, Liqiang Wang, Qi Zhou, Wei Li, Yukai Wang, Baoyang Hu. Safety and efficacy of human ESC-derived corneal endothelial cells for corneal endothelial dysfunction. CELL & BIOSCIENCE[J]. 2023, 13(1): 201, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10629087/.
[8] Wang, Chenxin, Liu, Jingjing, Li, Wei. 'Off the shelf' immunotherapies: Generation and application of pluripotent stem cell-derived immune cells. CELL PROLIFERATION[J]. 2023, 56(4): e13425, http://dx.doi.org/10.1111/cpr.13425.
[9] Wen-Lan Yang, Weinan Qiu, Ting Zhang, Kai Xu, Zi-Juan Gu, Yu Zhou, Heng-Ji Xu, Zhong-Zhou Yang, Bin Shen, Yong-Liang Zhao, Qi Zhou, Ying Yang, Wei Li, Peng-Yuan Yang, Yun-Gui Yang. Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis. Nature Communications[J]. 2023, 14(1): 1-16, http://dx.doi.org/10.1038/s41467-023-36595-w.
[10] Wang, Xinge, Chen, Yangcan, Cheng, Xuejia, Wang, SiQi, Hu, Yanping, Feng, Yingmei, Jin, Ronghua, Zhou, Kangping, Liu, Ti, Wang, Jianxing, Pan, Kai, Liu, Bing, Xiang, Jie, Wang, Yanping, Zhou, Qi, Zhang, Ying, Pan, Weiye, Li, Wei. CDetection.v2: One-pot assay for the detection of SARS-CoV-2. FRONTIERS IN MICROBIOLOGY[J]. 2023, 14:1158163: http://dx.doi.org/10.3389/fmicb.2023.1158163.
[11] Ji, TianTian, Niu, ShuaiShuai, Fang, MingHui, Xu, LingXue, Wang, Xin, Wu, Jun, Xu, Fei, Zhang, Meng, Niu, Rui, Wu, Jun, Wang, Lei, Li, ZhiKun, Yang, YongGuang, Hao, Jie, Li, Wei, Hu, Zheng, Zhou, Qi. Genome editing HLA alleles for a pilot immunocompatible hESC line in a Chinese hESC bank for cell therapies. CELL PROLIFERATION[J]. 2023, 56(5): e13471, https://www.doi.org/10.1111/cpr.13471.
[12] Wang, Chenxin, Fang, Sen, Chen, Yangcan, Tang, Na, Jiao, Guanyi, Hu, Yanping, Li, Jing, Shan, Qingtong, Wang, Xin, Feng, Guihai, Zhou, Qi, Li, Wei. High-efficiency targeted transgene integration via primed micro-homologues. CELL DISCOVERY[J]. 2023, 9(1): 69, http://dx.doi.org/10.1038/s41421-023-00552-0.
[13] Yangcan Chen, Yanping Hu, Shengqiu Luo, Xinge Wang, Bangwei Mao, Yi Chen, Jing Xu, Zhikun Li, Qi Zhou, Wei Li. Computer-aided engineering of CRISPR-Cas proteins for enhanced human genome editing. 中国科学:生命科学英文版[J]. 2023, 66(4): 883-886, http://lib.cqvip.com/Qikan/Article/Detail?id=7109454744.
[14] Liu, Chao, Li, Wei. Advances in haploid embryonic stem cell research(dagger). BIOLOGY OF REPRODUCTION[J]. 2022, 107(1): 250-260, http://dx.doi.org/10.1093/biolre/ioac110.
[15] Wang, Si, Cheng, Fang, Ji, Qianzhao, Song, Moshi, Wu, Zeming, Zhang, Yiyuan, Ji, Zhejun, Feng, Huyi, Belmonte, Juan Carlos Izpisua, Zhou, Qi, Qu, Jing, Li, Wei, Liu, GuangHui, Zhang, Weiqi. Hyperthermia differentially affects specific human stem cells and their differentiated derivatives. PROTEIN & CELL[J]. 2022, 13(8): 615-622, http://dx.doi.org/10.1007/s13238-021-00887-y.
[16] Li, Guanglei, Li, Xiangyang, Zhuang, Songkuan, Wang, Liren, Zhu, Yifan, Chen, Yangcan, Sun, Wen, Wu, Zeguang, Zhou, Zhuo, Chen, Jia, Huang, Xingxu, Wang, Jin, Li, Dali, Li, Wei, Wang, Haoyi, Wei, Wensheng. Gene editing and its applications in biomedicine. SCIENCE CHINA-LIFE SCIENCES[J]. 2022, 65(4): 660-700, http://dx.doi.org/10.1007/s11427-021-2057-0.
[17] Ren, Jilong, Yu, Dawei, Wang, Jing, Xu, Kai, Xu, Yanan, Sun, Renren, An, Peipei, Li, Chongyang, Feng, Guihai, Zhang, Ying, Dai, Xiangpeng, Zhao, Hongye, Wang, Zhengzhu, Han, Zhiqiang, Zhu, Haibo, Ding, Yuchun, You, Xiaoyan, Liu, Xueqin, Wu, Meng, Luo, Lin, Li, Ziyi, Yang, YongGuang, Hu, Zheng, Wei, HongJiang, Ge, Liangpeng, Hai, Tang, Li, Wei. Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver. CELL AND BIOSCIENCE[J]. 2022, 12(1): http://dx.doi.org/10.1186/s13578-022-00760-3.
[18] Hu, Yanping, Li, Wei. Development and Application of CRISPR-Cas Based Tools. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY[J]. 2022, 10: http://dx.doi.org/10.3389/fcell.2022.834646.
[19] Yanping Hu, Yangcan Chen, Jing Xu, Xinge Wang, Shengqiu Luo, Bangwei Mao, Qi Zhou, Wei Li. Metagenomic discovery of novel CRISPR-Cas13 systems. CELLDISCOVERY[J]. 2022, 8(1): 1-4, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554183/.
[20] Jiao, Guanyi, Wang, Chenxin, Chen, Yangcan, Dai, Moyu, Zhang, Ying, Li, Wei. Enhancing targeted transgene knock-in by donor recruitment. CELL PROLIFERATION[J]. 2022, 55(1): 
[21] Jiabao Han, Liyu Zhu, Jingwen Zhang, Lu Guo, Xuehan Sun, Cheng Huang, Kai Xu, Ying Zhang, Wei Li, Qi Zhou. Rational engineering of adeno-associated virus capsid enhances human hepatocyte tropism and reduces immunogenicity. Cell Proliferation[J]. 2022, 55(12): e13339-0, 
[22] ZhengQuan He, XueWei Yuan, ZongBao Lu, YuHuan Li, YuFei Li, Xin Liu, Liu Wang, Ying Zhang, Qi Zhou, Wei Li. Pharmacological regulation of tissue fibrosis by targeting the mechanical contraction of myofibroblasts. FUNDAMENTAL RESEARCH[J]. 2022, 2(1): 37-47, 
[23] Lu Guo, Zhikun Li, Yuhuan Li, Bin Qu, Guanyi Jiao, Chen Liang, Zongbao Lu, XinGe Wang, Cheng Huang, Hongwei Du, Jianmin Liang, Qi Zhou, Wei Li. Treatment of Glutaric Aciduria Type I (GA-I) via Intracerebroventricular Delivery of GCDH. FUNDAMENTAL RESEARCH[J]. 2022, http://dx.doi.org/10.1016/j.fmre.2022.08.013.
[24] Chen, Yangcan, Hu, Yanping, Wang, Xinge, Luo, Shengqiu, Yang, Ning, Chen, Yi, Li, Zhikun, Zhou, Qi, Li, Wei. Synergistic engineering of CRISPR-Cas nucleases enables robust mammalian genome editing. Innovation (Camb)[J]. 2022, 3(4): 100264, 
[25] He, ZhengQuan, Li, YuHuan, Feng, GuHai, Yuan, XueWei, Lu, ZongBao, Dai, Min, Hu, YanPing, Zhang, Ying, Zhou, Qi, Li, Wei. Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons. ADVANCED SCIENCE[J]. 2022, 9(13): http://dx.doi.org/10.1002/advs.202104682.
[26] Wang, Liying, Xu, Zhiliang, Wang, Libin, Liu, Chao, Wei, Huafang, Zhang, Ruidan, Chen, Yinghong, Wang, Lina, Liu, Wenwen, Xiao, Sai, Li, Wei, Li, Wei. Histone H2B ubiquitination mediated chromatin relaxation is essential for the induction of somatic cell reprogramming. CELL PROLIFERATION[J]. 2021, 54(8): http://dx.doi.org/10.1111/cpr.13080.
[27] Lu, Xukun, Zhang, Yu, Wang, Lijuan, Wang, Leyun, Wang, Huili, Xu, Qianhua, Xiang, Yunlong, Chen, Chaolei, Kong, Feng, Xia, Weikun, Lin, Zili, Ma, Sinan, Liu, Ling, Wang, Xiangguo, Ni, Hemin, Li, Wei, Guo, Yong, Xie, Wei. Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting. SCIENCE ADVANCES[J]. 2021, 7(48): 
[28] Fu, Rui, Fang, Minghui, Xu, Kai, Ren, Jilong, Zou, Jun, Su, Long, Chen, Xinxin, An, PeiPei, Yu, Dawei, Ka, Meina, Hai, Tang, Li, Ziyi, Li, Wei, Yang, Yongguang, Zhou, Qi, Hu, Zheng. Generation ofGGTA1(-/-)beta 2M(-/-)CIITA(-/-)Pigs Using CRISPR/Cas9 Technology to Alleviate Xenogeneic Immune Reactions. TRANSPLANTATION[J]. 2020, 104(8): 1566-1573, http://dx.doi.org/10.1097/TP.0000000000003205.
[29] Wang, LeYun, Li, ZhiKun, Wang, LiBin, Liu, Chao, Sun, XueHan, Feng, GuiHai, Wang, JiaQiang, Li, YuFei, Qiao, LianYong, Nie, Hu, Jiang, LiYuan, Sun, Hao, Xie, YaLi, Ma, SiNan, Wan, HaiFeng, Lu, FaLong, Li, Wei, Zhou, Qi. Overcoming Intrinsic H3K27me3 Imprinting Barriers Improves Post-implantation Development after Somatic Cell Nuclear Transfer. CELL STEM CELL[J]. 2020, 27(2): 315-325.e5, http://dx.doi.org/10.1016/j.stem.2020.05.014.
[30] Li, Yufei, Li, Wei, Zhou, Qi. Haploid pluripotent stem cells: twofold benefits with half the effort in genetic screening and reproduction. CURRENT OPINION IN GENETICS & DEVELOPMENT[J]. 2020, 64: 6-12, http://dx.doi.org/10.1016/j.gde.2020.05.013.
[31] Fu, Rui, Yu, Dawei, Ren, Jilong, Li, Chongyang, Wang, Jing, Feng, Guihai, Wang, Xuepeng, Wan, Haifeng, Li, Tianda, Wang, Libin, Zhang, Ying, Hai, Tang, Li, Wei, Zhou, Qi. Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs. PROTEIN & CELL[J]. 2020, 11(2): 97-107, http://lib.cqvip.com/Qikan/Article/Detail?id=7101576097.
[32] 李鹏承, 万海峰, 李伟. 非人灵长类胚胎工程研究进展. 生命科学[J]. 2020, 32(7): 661-663, http://lib.cqvip.com/Qikan/Article/Detail?id=7102923976.
[33] Chen, Baohui, Niu, Yuyu, Wang, Haoyi, Wang, Kejian, Yang, Hui, Li, Wei. Recent advances in CRISPR research. PROTEIN & CELL[J]. 2020, 11(11): 786-791, http://lib.cqvip.com/Qikan/Article/Detail?id=7103601388.
[34] Ren, Jilong, Yu, Dawei, Fu, Rui, An, Peipei, Sun, Renren, Wang, Zhengzhu, Guo, Runfa, Li, Haoyun, Zhang, Ying, Li, Ziyi, Yang, YongGuang, Li, Wei, Hai, Tang, Hu, Zheng. IL2RG-deficient minipigs generated via CRISPR/Cas9 technology support the growth of human melanoma-derived tumours. CELL PROLIFERATION[J]. 2020, 53(10): http://dx.doi.org/10.1111/cpr.12863.
[35] Qu, Bin, Wu, Shijing, Jiao, Guanyi, Zou, Xuan, Li, Zhikun, Guo, Lu, Sun, Xuehan, Huang, Cheng, Sun, Zixi, Zhang, Ying, Li, Hui, Zhou, Qi, Sui, Ruifang, Li, Wei. Treating Bietti crystalline dystrophy in a high-fat diet-exacerbated murine model using gene therapy. GENE THERAPY[J]. 2020, 27(7-8): 370-382, http://dx.doi.org/10.1038/s41434-020-0159-3.
[36] Mao, Junjie, Xu, Kai, Han, Jiabao, Feng, Guihai, Zhang, Ying, Li, Wei. Rapid construction of a whole-genome mutant library by combining haploid stem cells and inducible self-inactivating PiggyBac transposon. PROTEIN & CELL[J]. 2020, 11(6): 452-457, http://lib.cqvip.com/Qikan/Article/Detail?id=7102355335.
[37] Li, Jing, Wang, Chenxin, Feng, Guihai, Zhang, Linlin, Chen, Guilai, Sun, Hao, Wang, Jiaqiang, Zhang, Ying, Zhou, Qi, Li, Wei. Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing. CELL PROLIFERATION[J]. 2020, 53(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000500078600001.
[38] 崔彤彤, 李治琨, 周琪, 李伟. Current advances in haploid stem cells. PROTEIN & CELL[J]. 2020, 11(1): 23-33, https://doaj.org/article/34aa6dc9da15485ab23c53a721e38c47.
[39] Li, Yufei, Wang, Leyun, Zhang, Linlin, He, Zhengquan, Feng, Guihai, Sun, Hao, Wang, Jiaqiang, Li, Zhikun, Liu, Chao, Han, Jiabao, Mao, Junjie, Li, Pengcheng, Yuan, Xuewei, Jiang, Liyuan, Zhang, Ying, Zhou, Qi, Li, Wei. Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I. JOURNAL OF CELL BIOLOGY[J]. 2019, 218(5): 1553-1563, https://www.webofscience.com/wos/woscc/full-record/WOS:000466980400014.
[40] Teng, Fei, Li, Jing, Cui, Tongtong, Xu, Kai, Guo, Lu, Gao, Qingqin, Feng, Guihai, Chen, Chuanyuan, Han, Dali, Zhou, Qi, Li, Wei. Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds. GENOME BIOLOGY[J]. 2019, 20(1): 15, https://doaj.org/article/ef19e2ad7d1c4c9788a858a91d36f8cb.
[41] Teng, Fei, Guo, Lu, Cui, Tongtong, Wang, XinGe, Xu, Kai, Gao, Qingqin, Zhou, Qi, Li, Wei. CDetection: CRISPR-Cas12b-based DNA detection with sub-attomolar sensitivity and single-base specificity. GENOME BIOLOGY[J]. 2019, 20(1): 132, http://dx.doi.org/10.1186/s13059-019-1742-z.
[42] Wenliang Zhu, Boya Zhang, Mengqi Li, Fan Mo, Tingwei Mi, Yihui Wu, Zhaoqian Teng, Qi Zhou, Wei Li, Baoyang Hu. Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome. NATURE COMMUNICATIONS[J]. 2019, 10(1): 1-18, https://doaj.org/article/fe289d2c0c864031a37e09fb8593c020.
[43] Cui, Tongtong, Jiang, Liyuan, Li, Tianda, Teng, Fei, Feng, Guihai, Wang, Xuepeng, He, Zhengquan, Guo, Lu, Xu, Kai, Mao, Yihuan, Wang, Leyun, Yuan, Xuewei, Wang, Liu, Li, Wei, Zhou, Qi. Derivation of Mouse Haploid Trophoblast Stem Cells. CELL REPORTS[J]. 2019, 26(2): 407-414.e5, http://dx.doi.org/10.1016/j.celrep.2018.12.067.
[44] Teng, Fei, Cui, Tongtong, Gao, Qingqin, Guo, Lu, Zhou, Qi, Li, Wei. Artificial sgRNAs engineered for genome editing with new Cas12b orthologs. CELL DISCOVERY[J]. 2019, 5: 23, https://doaj.org/article/e8ef22cb7fda4f2b987b008ac5d4e070.
[45] Yuan, Xuewei, He, Zhengquan, Mao, Junjie, Hu, Yanping, Liu, Xin, Guo, Jia, Liu, Zhonghua, Zhang, Ying, Li, Wei, Zhou, Qi. Reprogramming of fibroblasts to uterine glandular epithelium by a chemical cocktail induction. CELL DISCOVERY[J]. 2019, 5: 26, http://dx.doi.org/10.1038/s41421-019-0096-8.
[46] 高情琴, 陈阳灿, 滕飞, 李伟. CRISPR基因编辑:更高效、更便捷、更普适. 前沿科学[J]. 2019, 13(3): 8-13, http://lib.cqvip.com/Qikan/Article/Detail?id=7002989691.
[47] Teng, Fei, Li, Wei, Zhou, Qi. Synthetic chromosome evolves the yeast genome. SCIENCECHINALIFESCIENCES[J]. 2019, 62(5): 708-709, http://lib.cqvip.com/Qikan/Article/Detail?id=74678871504849574853484951.
[48] Zhang, Xinxin, Li, Tianda, Zhang, Linlin, Jiang, Liyuan, Cui, Tongtong, Yuan, Xuewei, Wang, Chenxin, Liu, Zhonghua, Zhang, Ying, Li, Wei, Zhou, Qi. Individual blastomeres of 4-and 8-cell embryos have ability to develop into a full organism in mouse. JOURNAL OF GENETICS AND GENOMICS[J]. 2018, 45(12): 677-680, http://lib.cqvip.com/Qikan/Article/Detail?id=6100251575.
[49] Teng, Fei, Cui, Tongtong, Feng, Guihai, Guo, Lu, Xu, Kai, Gao, Qingqin, Li, Tianda, Li, Jing, Zhou, Qi, Li, Wei. Repurposing CRISPR-Cas12b for mammalian genome engineering. CELLDISCOVERY[J]. 2018, 4(1): https://doaj.org/article/c5d0bf467b69475fa5a53db21f89f1aa.
[50] Wang, ChenXin, Cui, GuanShen, Liu, XiuYing, Xu, Kai, Wang, Meng, Zhang, XinXin, Jiang, LiYuan, Li, Ang, Yan, Ying, Lai, WeiYi, Sun, BaoFa, Jiang, GuiBin, Wang, HaiLin, Tong, WeiMin, Li, Wei, Wang, XiuJie, Yang, YunGui, Zhou, Qi. METTL3-mediated m6A modification is required for cerebellar development. PLoS Biology[J]. 2018, 16(6): https://doaj.org/article/ac22537f22f14d259073b36f082d0530.
[51] Tan, Yuanqing, Han, Pengcheng, Gu, Qi, Chen, Gang, Wang, Lei, Ma, Ruoyu, Wu, Jun, Feng, Chunjing, Zhang, Ying, Wang, Liu, Hu, Baoyang, Li, Wei, Hao, Jie, Zhou, Qi. Generation of clinical-grade functional cardiomyocytes from human embryonic stem cells in chemically defined conditions. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE[J]. 2018, 12(1): 153-163, https://www.webofscience.com/wos/woscc/full-record/WOS:000423431200070.
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