基本信息

肖景发  男  博导  中国科学院北京基因组研究所(国家生物信息中心)
电子邮件: xiaojingfa@big.ac.cn
通信地址: 北京市朝阳区北辰西路1-7号
邮政编码: 100101

研究领域

基因组学和生物信息学


招生信息

招收生物信息学、计算机科学、数学和生物学等相关专业背景考生

招生专业
0710J3-生物信息学
0710Z1-基因组学
招生方向
生命与健康大数据整合和挖掘

教育背景

1998-09--2003-07   吉林大学   博士学位
1991-09--1995-07   四川大学生物系   学士学位

工作经历

   
工作简历
2012-05~现在, 中国科学院北京基因组研究所, 研究员
2007-02~2012-05,中国科学院北京基因组研究所, 副研究员
2005-11~2007-02,美国犹他大学, 博士后
2003-07~2005-08,协和医科大学药物研究所, 博士后
1995-07~1998-08,沈阳第一制药厂, 助理工程师
社会兼职
2018-01-01-今,科技资源导刊, 编委
2017-10-01-今,全国生物技术标准化技术委员会生物计量和质量控制分技术委员会, 委员
2016-03-19-2017-12-31,Frontiers in Plant Science, 副主编
2013-08-31-今,遗传学会基因组学专业委员会, 委员
2013-02-28-今,PLoS One 杂志, 学术编委
2012-05-01-今,Genomics, Proteomics and Bioinformatics, 学术编委
2012-04-30-今,Frontiers in Plant Science, 学术编委
2011-09-01-今,运筹学会系统生物学分会, 理事

教授课程

生命组学
大数据科学
生物信息学前沿讲座
基因组学前沿
基因组学前沿讲座
基因组信息系统与实践
基因组学
基因组学和生物技术前沿讲座
基因组学实用技术讲座

专利与奖励

   
专利成果
( 1 ) 编码蛋白质DNA序列并行比对软件, 发明, 2012, 第 2 作者, 专利号: 2012SR041110
( 2 ) RNA data anotation pipeline software 软件著作权, 发明, 2012, 第 2 作者, 专利号: 2012SR013930
( 3 ) 泛基因组自动化分析软件计算机软件著作权, 发明, 2013, 第 2 作者, 专利号: 2013SR053017
( 4 ) 人类转录组注释系统软件著作权, 发明, 2013, 第 2 作者, 专利号: 2013SR058058
( 5 ) 虚拟中国人动态基因组数据库系统软件著作权, 发明, 2014, 第 1 作者, 专利号: 2014SR113149
( 6 ) 大规模基因组数据泛基因组特征分析软件, 发明, 2014, 第 2 作者, 专利号: 2014SR113147
( 7 ) 基于RNA重亚硫酸盐测序数据的快速比对和注释软件, 发明, 2016, 第 2 作者, 专利号: 2017SR093096
( 8 ) 基于核心基因组结构框架的原核生物拼接软件, 发明, 2017, 第 2 作者, 专利号: 2017SR714259
( 9 ) 哺乳动物转录组数据库, 发明, 2017, 第 1 作者, 专利号: 2017SR714249
( 10 ) 泛基因组深度分析和可视化软件, 发明, 2019, 第 1 作者, 专利号: 2019SR0347218
( 11 ) 多物种全基因组核小体定位图谱数据库系统, 发明, 2019, 第 1 作者, 专利号: 2019SR0347246

出版信息

   
发表论文
[1] Shuo Shi, Qiheng Qian, Shuhuan Yu, Qi Wang, Jinyue Wang, Jingyao Zeng, Zhenglin Du, Jingfa Xiao. RefRGim: an intelligent reference panel reconstruction method for genotype imputation with convolutional neural networks. Briefings in Bioinformatics[J]. 2021, 22(6): [2] Jiang, Meiye, Bu, Congfan, Zeng, Jingyao, Du, Zhenglin, Xiao, Jingfa. Applications and challenges of high performance computing in genomics. CCF TRANSACTIONS ON HIGH PERFORMANCE COMPUTINGnull. 2021, 3(4): 344-352, [3] 薛勇彪, 鲍一明, 章张, 赵文明, 肖景发. Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022. Nucleic Acids Research[J]. 2021, 50(D1): D27-D38, [4] Yuansheng Zhang, Dong Zou, Tongtong Zhu, Tianyi Xu, Ming Chen, Guangyi Niu, Wenting Zong, Rong Pan, Wei Jing, Jian Sang, Chang Liu, Yujia Xiong, Yubin Sun, Shuang Zhai, Huanxin Chen, Wenming Zhao, Jingfa Xiao, Yiming Bao, Lili Hao, Zhang Zhang. Gene Expression Nebulas (GEN): a comprehensive data portal integrating transcriptomic profiles across multiple species at both bulk and single-cell levels. Nucleic Acids Research[J]. 2021, 50(D1): D1016-D1024, [5] Jingyao Zeng, Yadong Zhang, Yunfei Shang, Jialin Mai, Shuo Shi, Mingming Lu, Congfan Bu, Zhewen Zhang, Zaichao Zhang, Yang Li, Zhenglin Du, Jingfa Xiao. CancerSCEM: a databaseof single-cell expression map across various human cancers. Nucleic Acids Research[J]. 2021, 50(D1): D1147-D1155, [6] Xue, Yongbiao, Bao, Yiming, Zhang, Zhang, Zhao, Wenming, Xiao, Jingfa, He, Shunmin, Zhang, Guoqing, Li, Yixue, Zhao, Guoping, Chen, Runsheng, Song, Shuhui, Ma, Lina, Zou, Dong, Tian, Dongmei, Li, Cuiping, Zhu, Junwei, Gong, Zheng, Chen, Meili, Wang, Anke, Ma, Yingke, Li, Mengwei, Teng, Xufei, Cui, Ying, Duan, Guangya, Zhang, Mochen, Jin, Tong, Shi, Chengmin, Du, Zhenglin, Zhang, Yadong, Liu, Chuandong, Li, Rujiao, Zeng, Jingyao, Hao, Lili, Jiang, Shuai, Chen, Hua, Han, Dali, Yongbiao, Xue, Zhang, Tao, Kang, Wang, Qu, Jing, Zhang, Weiqi, Liu, GuangHui, Liu, Lin, Zhang, Yang, Niu, Guangyi, Zhu, Tongtong, Feng, Changrui, Liu, Xiaonan, Zhang, Yuansheng, Li, Zhao, Chen, Ruru, Li, Qianpeng, Hua, Zhongyi, Jiang, Chao, Chen, Ziyuan, He, Fangshu, Zhao, Yuyang, Jin, Yan, Huang, Luqi, Yuan, Yuan, Zhou, Chenfen, Xu, Qingwei, He, Sheng, Ye, Wei, Cao, Ruifang, Wang, Pengyu, Ling, Yunchao, Yan, Xing, Wang, Qingzhong, Du, Qiang, Zong, Wenting, Kang, Hongen, Xiong, Zhuang, Huan, Wendi, Zhang, Sirui, Xia, Qiguang, Fan, Xiaojuan, Wang, Zefeng, Chen, Xu, Chen, Tingting, Zhang, Sisi, Tang, Bixia, Dong, Lili, Zhang, Zhewen, Wang, Zhonghuang, Kang, Hailong, Wang, Yanqing, Wu, Song, Wang, Honggen, Chen, Ming, Liu, Chang, Xiong, Yujia, Shao, Xueying, Li, Yanyan, Zhou, Honghong, Chen, Xiaomin, Zheng, Yu, Kang, Quan, Hao, Di, Zhang, Lili, Luo, Huaxia, Hao, Yajing, Zhang, Peng, Nie, Zhi, Yu, Shuhuan, Yang, Fei, Sang, Jian, Li, Zhaohua, Zhang, Xiangquan, Zhou, Qing, Zhai, Shuang, Zhang, Yaping, Wang, Guodong, Zhu, Qianghui, Li, Xin, Li, Menghua, Yan, Jun, Li, Chen, Wang, Zhennan, Wang, Xiangfeng, Liu, Yuanming, Luo, Hong, Wu, Xiaoyuan, Jing, HaiChun, Song, Tinrui, Zhao, Yi, Mehmood, Furrukh, Ali, Shahid, Ali, Amjad, Saleem, Shoaib, Hussain, Irfan, Abbasi, Amir A, Zuo, Zhixiang, Ren, Jian, Zhang, Xinxin, Xiao, Yun, Li, Xia, Tu, Yiran, Xue, Yu, Wu, Wanying, Ji, Peifeng, Zhao, Fangqing, Meng, Xianwen, Peng, Di, Luo, Hao, Gao, Feng, Ning, Wanshan, Lin, Shaofeng, Liu, Teng, Guo, AnYuan, Yuan, Hao, Zhang, Yong E, Tan, Xiaodan, Zhang, Weizhi, Xie, Yubin, Wang, Chenwei, Liu, ChunJie, Yang, DeChang, Tian, Feng, Gao, Ge, Tang, Dachao, Yao, Lan, Cui, Qinghua, An, Ni A, Li, ChuanYun, Luo, XiaoTong. Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021. Nucleic Acids Research[J]. 2021, 49(D1): D18-D28, http://dx.doi.org/10.1093/nar/gkaa1022.
[7] Zhang, Zhang, Zhao, Wenming, Xiao, Jingfa, Bao, Yiming, He, Shunmin, Zhang, Guoqing, Li, Yixue, Zhao, Guoping, Chen, Runsheng, Gao, Yang, Zhang, Chao, Yuan, Liyun, Xu, Shuhua, Ning, Zhilin, Lu, Yan, Zeng, Jingyao, Yuan, Na, Zhu, Junwei, Pan, Mengyu, Zhang, Hao, Wang, Qi, Shi, Shuo, Jiang, Meiye, Lu, Mingming, Qian, Qiheng, Gao, Qianwen, Shang, Yunfei, Wang, Jinyue, Du, Zhenglin, Tian, Dongmei, Wang, Pei, Tang, Bixia, Li, Cuiping, Teng, Xufei, Liu, Xiaonan, Zou, Dong, Song, Shuhui, Xiong, Zhuang, Li, Mengwei, Yang, Fei, Ma, Yingke, Sang, Jian, Li, Zhaohua, Li, Rujiao, Wang, Zhonghuang, Zhu, Qianghui, Li, Xin, Zhang, Sisi, Kang, Hailong, Dong, Lili, Ying, Cui, Duan, Guangya, Li, Menghua, Zhi, Xiaoyang, Ling, Yunchao, Cao, Ruifang, Jiang, Zhao, Zhou, Haokui, Lv, Daqing, Liu, Wan, Klenk, HansPeter, Zhang, Yadong, Zhang, Zhewen, Chen, Tingting, Chen, Xu, Wang, Yanqing, Wu, Song, Gong, Zheng, Chen, Meili, Fang, Shuangsang, Zhang, Lili, Guo, Jincheng, Niu, Yiwei, Wu, Yang, Li, Hui, Zhao, Lianhe, Li, Xiyuan, Teng, Xueyi, Sun, Xianhui, Sun, Liang, Zhao, Yi, Wang, Jiajia, Zhang, Peng, Li, Yanyan, Zheng, Yu, Chen, Xiaomin, Xue, Hua, Teng, Yiheng, Kang, Quan, Hao, Yajing, Cao, Jiabao, Liu, Lin, Li, Zhao, Li, Qianpeng, Du, Qiang, Abbasi, Amir A, Shireen, Huma, Pervaiz, Nashaiman, Batool, Fatima, Raza, Rabail Z, Ma, Lina, Niu, Guangyi, Zhang, Yuansheng, Zhu, Tongtong, Hao, Lili, Wang, Guoliang, Yan, Jun, Li, Chen, Wang, Zhennan, Wang, Xiangfeng, Li, Zhonghai, Zhang, Yang, Wang, Houling, Zhang, Yi, Xia, Xinli, Guo, Hongwei, Zhu, Junwen, Zhou, Qing, Kang, Hongen, Lan, Li, Zhang, Xin, Xue, Yongbiao, Sun, Yubin, Zhai, Shuang, Yu, Lei, Sun, Mingyuan, Chen, Huanxin, Hu, Hui, Guo, AnYuan, Lin, Shaofeng, Xue, Yu, Wang, Chenwei, Ning, Wanshan, Zhang, Xinxin, Xiao, Yun, Li, Xia, Tu, Yiran, Wu, Wanying, Ji, Peifeng, Zhao, Fangqing, Luo, Hao, Gao, Feng, Guo, Yaping, Yuan, Hao, Zhang, Yong E, Zhang, Qiong, Zhou, Jiaqi, Huang, Zhou, Cui, Qinghua, Miao, YaRu, Ruan, Chen, Yuan, Chunhui, Chen, Ming, Jin, JinPu, Tian, Feng, Gao, Ge, Shi, Ying, Yao, Lan, Li, Xiangshang, Li, ChuanYun, Tang, Qing, Peng, Di. Database Resources of the National Genomics Data Center in 2020. NUCLEIC ACIDS RESEARCH[J]. 2020, 48(D1): D24-D33, https://www.webofscience.com/wos/woscc/full-record/WOS:000525956700004.
[8] Zhang, Zhang, Song, Shuhui, Yu, Jun, Zhao, Wenming, Xiao, Jingfa, Bao, Yiming. The Elements of Data Sharing. GENOMICS PROTEOMICS & BIOINFORMATICS[J]. 2020, 18(1): 1-4, http://lib.cqvip.com/Qikan/Article/Detail?id=00002HUHLL7G7JP0MPDO8JP1MNR.
[9] Xiao Jingfa. Genome and Dual-RNA-Seq Data Analyses Reveal the Inter-action between Ilyonectria destructans CD-56 and Ginseng. Scientific Reports. 2020, [10] Zhang, Yadong, Zhang, Zhewen, Zhang, Hao, Zhao, Yongbing, Zhang, Zaichao, Xiao, Jingfa. PADS Arsenal: a database of prokaryotic defense systems related genes. NUCLEIC ACIDS RESEARCH[J]. 2020, 48(D1): D590-D598, https://www.webofscience.com/wos/woscc/full-record/WOS:000525956700080.
[11] Song, Shuhui, Ma, Lina, Zou, Dong, Tian, Dongmei, Li, Cuiping, Zhu, Junwei, Chen, Meili, Wang, Anke, Ma, Yingke, Li, Mengwei, Teng, Xufei, Cui, Ying, Duan, Guangya, Zhang, Mochen, Jin, Tong, Shi, Chengmin, Du, Zhenglin, Zhang, Yadong, Liu, Chuandong, Li, Rujiao, Zeng, Jingyao, Hao, Lili, Jiang, Shuai, Chen, Hua, Han, Dali, Xiao, Jingfa, Zhang, Zhang, Zhao, Wenming, Xue, Yongbiao, Bao, Yiming. The Global Landscape of SARS-CoV-2 Genomes, Variants, and Haplotypes in 2019nCoVR. GENOMICS PROTEOMICS & BIOINFORMATICS[J]. 2020, 18(6): 749-759, http://dx.doi.org/10.1016/j.gpb.2020.09.001.
[12] Li, Zhao, Liu, Lin, Jiang, Shuai, Li, Qianpeng, Feng, Changrui, Du, Qiang, Zou, Dong, Xiao, Jingfa, Zhang, Zhang, Ma, Lina. LncExpDB: an expression database of human long non-coding RNAs. Nucleic Acids Research[J]. 2020, 49(D1): D962-D968, http://dx.doi.org/10.1093/nar/gkaa850.
[13] Teng, Xufei, Li, Qianpeng, Li, Zhao, Zhang, Yuansheng, Niu, Guangyi, Xiao, Jingfa, Yu, Jun, Zhang, Zhang, Song, Shuhui. Compositional Variability and Mutation Spectra of Monophyletic SARS-CoV-2 Clades. GENOMICS PROTEOMICS & BIOINFORMATICS[J]. 2020, 18(6): 648-663, http://dx.doi.org/10.1016/j.gpb.2020.10.0031672-0229.
[14] Zhao, Yongbing, Wang, Jinyue, Liang, Fang, Liu, Yanxia, Wang, Qi, Zhang, Hao, Jiang, Meiye, Zhang, Zhewen, Zhao, Wenming, Bao, Yiming, Zhang, Zhang, Wu, Jiayan, Asmann, Yan W, Li, Rujiao, Xiao, Jingfa. NucMap: a database of genome-wide nucleosome positioning map across species. NUCLEIC ACIDS RESEARCH[J]. 2019, 47(D1): D163-D169, https://www.webofscience.com/wos/woscc/full-record/WOS:000462587400027.
[15] Zhang, Zhang, Zhao, Wenming, Xiao, Jingfa, Bao, Yiming, Wang, Fan, Hao, Lili, Zhu, Junwei, Chen, Tingting, Zhang, Sisi, Chen, Xu, Tang, Bixia, Zhou, Qing, Wang, Zhonghuang, Dong, Lili, Wang, Yanqing, Ma, Yingke, Zhang, Zhewen, Wang, Zhonghuang, Chen, Meili, Tian, Dongmei, Li, Cuiping, Teng, Xufei, Du, Zhenglin, Yuan, Na, Zeng, Jingyao, Wang, Jinyue, Shi, Shuo, Zhang, Yadong, Wang, Qi, Pan, Mengyu, Qian, Qiheng, Song, Shuhui, Niu, Guangyi, Li, Man, Xia, Lin, Zou, Dong, Zhang, Yuansheng, Sang, Jian, Li, Mengwei, Zhang, Yang, Wang, Pei, Gao, Qianwen, Liang, Fang, Li, Rujiao, Liu, Lin, Cao, Jiabao, abbasi, Amir A, Shireen, Huma, Li, Zhao, Xiong, Zhuang, Jiang, Meiye, Guo, Tongkun, Li, Zhaohua, Zhang, Hao, Ma, Lina, Gao, Ran, Zhang, Tao, Li, Wulue, Zhang, Xiangquan, Lan, Li, Zhai, Shuang, Zhang, Yaping, Wang, Guodong, Wang, Zhennan, Xue, Yongbiao, Sun, Yubin, Yu, Lei, Sun, Mingyuan, Chen, Huanxin, Hu, Hui, Guo, AnYuan, Lin, Shaofeng, Xue, Yu, Wang, Chenwei, Ning, Wanshan, Zhang, Ying, Luo, Hao, Gao, Feng, Guo, Yaping, Zhang, Qiong, Zhou, Jiaqi, Huang, Zhou, Cui, Qinghua, Miao, YaRu, Ruan, Chen, Yuan, Chunhui, Chen, Ming, Jinpu, Jin, Gao, Ge, Xu, Haodong, Li, Yumei, Li, ChuanYun, Tang, Qing, Peng, Di, Deng, Wankun, Big Data Ctr Members. Database Resources of the BIG Data Center in 2019. NUCLEIC ACIDS RESEARCH[J]. 2019, 47(D1): D8-D14, http://dx.doi.org/10.1093/nar/gky993.
[16] Du, Zhenglin, Ma, Liang, Qu, Hongzhu, Chen, Wei, Zhang, Bing, Lu, Xi, Zhai, Weibo, Sheng, Xin, Sun, Yongqiao, Li, Wenjie, Lei, Meng, Qi, Qiuhui, Yuan, Na, Shi, Shuo, Zeng, Jingyao, Wang, Jinyue, Yang, Yadong, Liu, Qi, Hong, Yaqiang, Dong, Lili, Zhang, Zhewen, Zou, Dong, Wang, Yanqing, Song, Shuhui, Liu, Fan, Fang, Xiangdong, Chen, Hua, Liu, Xin, Xiao, Jingfa, Zeng, Changqing. Whole Genome Analyses of Chinese Population and De Novo Assembly of A Northern Han Genome. GENOMICS PROTEOMICS & BIOINFORMATICS[J]. 2019, 17(3): 229-247, http://lib.cqvip.com/Qikan/Article/Detail?id=71806673504849574851484851.
[17] Chen, Xinyu, Zhang, Yadong, Zhang, Zhewen, Zhao, Yongbing, Sun, Chen, Yang, Ming, Wang, Jinyue, Liu, Qian, Zhang, Baohua, Chen, Meili, Yu, Jun, Wu, Jiayan, Jin, Zhong, Xiao, Jingfa. PGAweb: A Web Server for Bacterial Pan-Genome Analysis. FRONTIERS IN MICROBIOLOGY[J]. 2018, 9: http://www.corc.org.cn/handle/1471x/2374278.
[18] Li, Rujiao, Liang, Fang, Li, Mengwei, Zou, Dong, Sun, Shixiang, Zhao, Yongbing, Zhao, Wenming, Bao, Yiming, Xiao, Jingfa, Zhang, Zhang. MethBank 3.0: a database of DNA methylomes across a variety of species. NUCLEIC ACIDS RESEARCH[J]. 2018, 46(D1): D288-D295, https://www.webofscience.com/wos/woscc/full-record/WOS:000419550700044.
[19] Xu, Xingjian, Hao, Lili, Zhu, Junwei, Zhou, Qing, Song, Fuhai, Chen, Tingting, Zhang, Sisi, Dong, Lili, Lan, Li, Wang, Yanqing, Liang, Fang, Cao, Jiabao, Liu, Fang, Liu, Lin, Wang, Fan, Ma, Yingke, Zhang, Lijuan, Chen, Meili, Tian, Dongmei, Li, Cuiping, Du, Zhenglin, Yuan, Na, Zeng, Jingyao, Zhang, Zhewen, Wang, Jinyue, Shi, Shuo, Zhang, Yadong, Pan, Mengyu, Tang, Bixia, Zou, Dong, Song, Shuhui, Sang, Jian, Xia, Lin, Wang, Zhennan, Li, Man, Niu, Guangyi, Zhang, Yang, Sheng, Xin, Lu, Mingming, Wang, Qi, Liang, Fang, Li, Mengwei, Sun, Shixiang, Li, Rujiao, Yu, Chunlei, Wang, Guangyu, Li, Man, Yin, Hongyan, Ma, Lina, Chen, Huanxin, Sun, Yubin, Yu, Lei, Zhai, Shuang, Sun, Mingyuan, Zhang, Zhang, Zhao, Wenming, Xiao, Jingfa, Bao, Yiming, Song, Shuhui, Miao, YaRu, Guo, AnYuan, Lin, Shaofeng, Xue, Yu, Luo, Hao, Gao, Feng, Ma, Wei, Cui, Qinghua, Xu, Haodong, BIG Data Ctr, BioCode Team, BioProject BioSample GSA Team, GWH Team, GVM Team, GEN Team, MethBank Team, Science Wikis Team, Hardware System Administration, Writing Grp, AnimalTFDB lncRNASNP Team, dbPAF Team, DEG DoriC Team, LncRNADis Team, PLMD Team. Database Resources of the BIG Data Center in 2018. NUCLEIC ACIDS RESEARCH[J]. 2018, 46(D1): D14-D20, http://dx.doi.org/10.1093/nar/gkx897.
[20] Zhao, Yongbing, Sun, Chen, Zhao, Dongyu, Zhang, Yadong, You, Yang, Jia, Xinmiao, Yang, Junhui, Wang, Lingping, Wang, Jinyue, Fu, Haohuan, Kang, Yu, Chen, Fei, Yu, Jun, Wu, Jiayan, Xiao, Jingfa. PGAP-X: extension on pan-genome analysis pipeline. BMC GENOMICS[J]. 2018, 19(S1): https://doaj.org/article/778dfe46a6174e30abed0aee35dafbc8.
[21] Jin, Jun, Li, Rujiao, Jiang, Chunlai, Zhang, Ruosi, Ge, Xiaomeng, Liang, Fang, Sheng, Xin, Dai, Wenwen, Chen, Meili, Wu, Jiayan, Xiao, Jingfa, Su, Weiheng. Transcriptome analysis reveals dynamic changes in coxsackievirus A16 infected HEK 293T cells. BMC GENOMICS[J]. 2017, 18(Suppl 1): http://dx.doi.org/10.1186/s12864-016-3253-6.
[22] Zhang, Zhang, Zhao, Wenming, Xiao, Jingfa, Song, Shuhui, Hao, Lili, Li, Rujiao, Ma, Lina, Sheng, Xin, Sang, Jian, Wang, Yanqing, Tang, Bixia, Zhang, Zhewen, BIG Data Ctr Members. The BIG Data Center: from deposition to integration to translation. NUCLEIC ACIDS RESEARCH[J]. 2017, 45(D1): D18-D24, http://dx.doi.org/10.1093/nar/gkw1060.
[23] Yuan, Lina, Yu, Yang, Zhu, Yanmin, Li, Yulai, Li, Changqing, Li, Rujiao, Ma, Qin, Siu, Gilman KitHang, Yu, Jun, Jiang, Taijiao, Xiao, Jingfa, Kang, Yu. GAAP: Genome-organization-framework-Assisted Assembly Pipeline for prokaryotic genomes. BMC GENOMICS[J]. 2017, 18(Suppl 1): http://dx.doi.org/10.1186/s12864-016-3267-0.
[24] Shi, Shuo, Yuan, Na, Yang, Ming, Du, Zhenglin, Wang, Jinyue, Sheng, Xin, Wu, Jiayan, Xiao, Jingfa. Comprehensive Assessment of Genotype Imputation Performance. HUMAN HEREDITY[J]. 2017, 83(3): 107-116, https://www.webofscience.com/wos/woscc/full-record/WOS:000456647500002.
[25] Sheng, Xin, Wu, Jiayan, Sun, Qianqian, Li, Xue, Xian, Feng, Sun, Manman, Fang, Wan, Chen, Meili, Yu, Jun, Xiao, Jingfa. MTD: a mammalian transcriptomic database to explore gene expression and regulation. BRIEFINGS IN BIOINFORMATICS[J]. 2017, 18(1): 28-36, https://www.webofscience.com/wos/woscc/full-record/WOS:000397059700003.
[26] Sun, Shixiang, Xiao, Jingfa, Zhang, Huiyong, Zhang, Zhang. Pangenome Evidence for Higher Codon Usage Bias and Stronger Translational Selection in Core Genes of Escherichia coli. FRONTIERS IN MICROBIOLOGY[J]. 2016, 7: http://www.corc.org.cn/handle/1471x/2374454.
[27] Xiao Jingfa. S-RNA: a novel mapping and annotation tool for RNA bisulfite sequencing data. computational biology and chemistry. 2016, [28] Tian, Xinpeng, Zhang, Zhewen, Yang, Tingting, Chen, Meili, Li, Jie, Chen, Fei, Yang, Jin, Li, Wenjie, Zhang, Bing, Zhang, Zhang, Wu, Jiayan, Zhang, Changsheng, Long, Lijuan, Xiao, Jingfa. Comparative Genomics Analysis of Streptomyces Species Reveals Their Adaptation to the Marine Environment and Their Diversity at the Genomic Level. FRONTIERS IN MICROBIOLOGY[J]. 2016, 7: http://ir.scsio.ac.cn/handle/344004/15393.
[29] Xiao Jingfa. A Brief Review of Online Software Packages for Pangenomics. Genomics, Proteomics & Bioinformatics. 2015, [30] Xiao Jingfa. Improvement of genome completeness and identification of novel full-length transcripts by RNA-seq in giant panda. Scientific Reports. 2015, [31] Zhao, Yongbing, Yin, Jinlong, Guo, Haiyan, Zhang, Yuyu, Xiao, Wen, Sun, Chen, Wu, Jiayan, Qu, Xiaobo, Yu, Jun, Wang, Xumin, Xiao, Jingfa. The complete chloroplast genome provides insight into the evolution and polymorphism of Panax ginseng. FRONTIERS IN PLANT SCIENCE[J]. 2015, 5: https://doaj.org/article/40897713878a43e591df7acdedbb8b99.
[32] Wang, Wenquan, Feng, Binxiao, Xiao, Jingfa, Xia, Zhiqiang, Zhou, Xincheng, Li, Pinghua, Zhang, Weixiong, Wang, Ying, Moller, Birger Lindberg, Zhang, Peng, Luo, MingCheng, Xiao, Gong, Liu, Jingxing, Yang, Jun, Chen, Songbi, Rabinowicz, Pablo D, Chen, Xin, Zhang, HongBin, Ceballos, Henan, Lou, Qunfeng, Zou, Meiling, Carvalho, Luiz J C B, Zeng, Changying, Xia, Jing, Sun, Shixiang, Fu, Yuhua, Wang, Haiyan, Lu, Cheng, Ruan, Mengbin, Zhou, Shuigeng, Wu, Zhicheng, Liu, Hui, Kannangara, Rubini Maya, Jorgensen, Kirsten, Neale, Rebecca Louise, Bonde, Maya, Heinz, Nanna, Zhu, Wenli, Wang, Shujuan, Zhang, Yang, Pan, Kun, Wen, Mingfu, Ma, PingAn, Li, Zhengxu, Hu, Meizhen, Liao, Wenbin, Hu, Wenbin, Zhang, Shengkui, Pei, Jinli, Guo, Anping, Guo, Jianchun, Zhang, Jiaming, Zhang, Zhengwen, Ye, Jianqiu, Ou, Wenjun, Ma, Yaqin, Liu, Xinyue, Tallon, Luke J, Galens, Kevin, Ott, Sandra, Huang, Jie, Xue, Jingjing, An, Feifei, Yao, Qingqun, Lu, Xiaojing, Fregene, Martin, Augusto Becerra LopezLavalle, L, Wu, Jiajie, You, Frank M, Chen, Meili, Hu, Songnian, Wu, Guojiang, Zhong, Silin, Ling, Peng, Chen, Yeyuan, Wang, Qinghuang, Liu, Guodao, Liu, Bin, Li, Kaimian, Peng, Ming. Cassava genome from a wild ancestor to cultivated varieties. NATURE COMMUNICATIONS[J]. 2014, 5: http://ir.scbg.ac.cn/handle/344003/17978.
[33] Ling, Yunchao, Jin, Zhong, Su, Mingming, Zhong, Jun, Zhao, Yongbing, Yu, Jun, Wu, Jiayan, Xiao, Jingfa. VCGDB: a dynamic genome database of the Chinese population. BMC GENOMICS[J]. 2014, 15(1): http://www.corc.org.cn/handle/1471x/2374155.
[34] Xiao Jingfa. PanGP: A tool for quick analyzing bacterial pan-genome profile. Bioinformatics. 2014, [35] Xiao Jingfa. Pan-genome provides insights into genome variation and evolution in Salmonella Paratyphi A. PLoS one. 2013, [36] Xiao Jingfa. Identification of Human HK Genes and Gene Expression Regulation Study in Cancer from Trancsriptomics Data Analysis. PLoS one. 2013, [37] Zhao, Dongyu, Wu, Jiayan, Zhou, Yuanyuan, Gong, Wei, Xiao, Jingfa, Yu, Jun. WikiCell: A Unified Resource Platform for Human Transcriptomics Research. OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY[J]. 2012, 16(6): 357-362, https://www.webofscience.com/wos/woscc/full-record/WOS:000305402500007.
[38] Zhao Qian, Xiao JingFa, Yu Jun. An Integrated Analysis of Lineage-specific Small Proteins Across Eight Eukaryotes Reveals Functional and Evolutionary Significance. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2012, 39(4): 359-367, https://www.webofscience.com/wos/woscc/full-record/WOS:000303278200009.
[39] Ming Yang, Yan Ge, Jiayan Wu, Jingfa Xiao, Jun Yu. Coevolution study of mitochondria respiratory chain proteins: Toward the understanding of protein-protein interaction. 遗传学报. 2011, 38(5): 201-207, http://lib.cqvip.com/Qikan/Article/Detail?id=38016235.
[40] Zhao, Yongbing, Xiao, Jingfa. Homology Modeling and Molecular Dynamics Simulation Studies of Human Type 1 3 beta-Hydroxysteroid Dehydrogenase: Toward the Understanding of Cofactor Specificity. JOURNAL OF COMPUTATIONAL CHEMISTRY[J]. 2011, 32(1): 33-42, https://www.webofscience.com/wos/woscc/full-record/WOS:000285311200004.
[41] Xiao Jingfa. Complete Genome Sequence of Streptococcus suis serotype 3 Strain JS3. Journal of Bacteriology. 2011, [42] Zhang, Anding, Yang, Ming, Hu, Pan, Wu, Jiayan, Chen, Bo, Hua, Yafeng, Yu, Jun, Chen, Huanchun, Xiao, Jingfa, Jin, Meilin. Comparative genomic analysis of Streptococcus suis reveals significant genomic diversity among different serotypes. BMC GENOMICS[J]. 2011, 12(1): 523-523, http://dx.doi.org/10.1186/1471-2164-12-523.
[43] Hu, Pan, Yang, Ming, Zhang, Anding, Wu, Jiayan, Chen, Bo, Hua, Yafeng, Yu, Jun, Xiao, Jingfa, Jin, Meilin. Complete Genome Sequence of Streptococcus suis Serotype 14 Strain JS14. JOURNAL OF BACTERIOLOGY[J]. 2011, 193(9): 2375-2376, https://www.webofscience.com/wos/woscc/full-record/WOS:000289670000044.
发表著作
(1) 基因组学核心实验方法, Genomics:essential methods, 科学出版社, 2012-03, 第 3 作者
(2) 第二代测序信息处理, next-generation DNA sequencing informatics, 科学出版社, 2014-06, 第 2 作者
(3) 基因组学与精准医学, Genomics and Precision Medicine, 上海交通大学出版社, 2017-12, 第 3 作者
(4) 系统生物学, Systems Biology, 重庆出版社, 2018-09, 第 5 作者

科研活动

   
科研项目
( 1 ) 生物信息技术共享、转化研究平台建设, 主持, 国家级, 2012-01--2015-12
( 2 ) 基于RNA-seq策略研究天然反义转录本的调控机制, 主持, 国家级, 2013-01--2016-12
( 3 ) 南海部分海区重要微生物类群基因组多样性初步研究, 主持, 部委级, 2013-01--2015-12
( 4 ) 基于深度测序和Hi-C方法对染色体层次上基因表达调控机制的研究, 主持, 国家级, 2015-01--2018-12
( 5 ) 中科院人群队列建立及精准医学研究, 主持, 部委级, 2015-10--2018-12
( 6 ) 精准医疗和个性化药物应用示范, 主持, 国家级, 2016-06--2020-12
( 7 ) 中国人群多组学参比数据库与分析系统建设, 参与, 国家级, 2017-06--2020-12
( 8 ) 微生物泛基因组信息深度挖掘新方法研究, 主持, 国家级, 2018-01--2021-12
( 9 ) 精准医疗大数据管理平台与应用示范, 主持, 国家级, 2017-01--2019-12
( 10 ) 基于基因型填补的无参肿瘤基因组变异鉴定新算法研究, 主持, 国家级, 2020-01--2023-12
( 11 ) 中国人群多组学知识库体系研发与建设, 主持, 部委级, 2020-01--2024-12
参与会议
(1)中科院人群队列建立和精准医学研究   第六届基因组科学与应用大会   2019-09-20
(2)NucMap: a database of genome-wide nucleosome positioning map across species   2019-04-08
(3)CASPMI project and Precision Medicine   2019-03-30
(4)CASPMI project and genetic reports study   2018-10-20
(5)Knowledge database of genome variation map for life and health   2018-07-25
(6)Comprehensive assessment of genotype imputation performance   2018-06-10
(7)De novo assembly of a northern Chinese genome.   Zhenglin Du, Na Yuan, Jingyao Zeng, Shuo Shi, Hongzhu Qu, Lili Dong, Jingfa Xiao   2018-04-08
(8)CAS precision medicine initiative   2018-03-26
(9)PGAP-X: Extension on pan-genome analysis pipeline   2017-09-20
(10)The BIG Data Center’s database resources: towards precision medicine   2017-03-29
(11)MTD: a mammalian transcriptomic database to explore gene expression and regulation   Shengxin, Jiayan Wu, Jun Yu, Jingfa Xiao   2016-10-03
(12)VCGDB: a dynamic genome database of the Chinese population   97. Yunchao Ling, Jiayan Wu, Jun Yu,    2015-04-23
(13)The complexity of mammalian transcriptomes and need for a pan-mammalian transcriptome project   JiayanWu, Lina Ma, Jingfa Xiao, Zhang Zhang, Xumin Wang, Shuangxiu Wu, Yu Kang, Songnian Hu, Jun Yu   2014-10-06
(14)Gene expression analysis of induced pluripotent stem cells from aneuploid chromosomal syndromes   Ruosi Zhang, Lili Hao, Lingping Wang, Meili Chen, Wen Li, M Esteban, Jun Yu,   2013-09-20
(15)General flow for high plant organelle genome sequence assembling and analysis    第六期木薯生物技术与功能基因组学研讨会   Yongbing Zhao, Jingfa Xiao.    2012-10-26
(16)Human cancer signatures in gene expression   Meili Chen, Jiayan Wu, Jingfa Xiao   2011-09-08
(17)Interrogating Transcriptome   第七届国际生物信息学研讨会   Jiang Zhu,Fuhong He, Jiayan Wu, Jingfa Xiao, Jun Yu   2009-06-18

指导学生

已指导学生

张再超  硕士研究生  071021-生物信息学  

孙世翔  硕士研究生  071021-生物信息学  

苏明明  硕士研究生  071021-生物信息学  

杨俊辉  硕士研究生  071021-生物信息学  

杨婷婷  硕士研究生  085211-计算机技术  

方皖  硕士研究生  085238-生物工程  

李雪  硕士研究生  085211-计算机技术  

王金月  博士研究生  0710J3-生物信息学  

张亚东  博士研究生  0710J3-生物信息学  

潘梦宇  硕士研究生  0710J3-生物信息学  

盛欣  博士研究生  0710J3-生物信息学  

高晨  硕士研究生  0710J3-生物信息学  

张莉娟  硕士研究生  0710Z1-基因组学  

王琪  硕士研究生  0710J3-生物信息学  

张好  硕士研究生  085211-计算机技术  

现指导学生

时硕  博士研究生  0710J3-生物信息学  

路明明  博士研究生  0710J3-生物信息学  

高千雯  硕士研究生  085238-生物工程  

尚云飞  硕士研究生  0710J3-生物信息学  

姜美叶  博士研究生  0710J3-生物信息学  

于淑欢  硕士研究生  0710J3-生物信息学  

聂致  硕士研究生  0710Z1-基因组学  

张好  博士研究生  0710J3-生物信息学  

钱启衡  博士研究生  0710J3-生物信息学