针对生物医用材料相关的抗菌、成骨、神经调控等关键事件，开展原创性研究，主要包括：

1. 电活性材料（压电、半导体等特殊生物材料：界面—细菌细胞之间的电子传递活动与机制）

2. 电控功能化（生理电场对生物材料的性能调控：物理外场—界面之间的电子传递调控与机制）

3. 电刺激治疗（基于新式电源与电极：外场对生命系统的物理化学调控效应与机制）

本课题组针对医用材料问题，立足交叉学科，在国家级人才项目支持下，进行创新乃至原创性研究。

校内每年招收博士、硕士各1名。招收联合培养学生不限。欢迎生物、材料、医学、工程、电子等多专业的同学报考。

常年招收博士后与科研助理，专业同上，欢迎垂询。

080501-材料物理与化学
083100-生物医学工程
071011-生物物理学

生物医用材料
电刺激治疗与电控功能化
生物-纳米界面

2005-09--2011-07   北京大学   博士
2001-09--2005-07   北京大学   学士

微纳生物电子学
纳米发电机与自驱动系统

   

（1） 中国科学院大学魏桥国科校长奖教金, 一等奖, 研究所（学校）, 2023
（2） 北京市自然科学奖, 二等奖, 省级, 2017
（3） 北京纳米能源所优秀职工, 一等奖, 研究所（学校）, 2017

（ 1 ） 一种黑色二氧化钛材料在黑暗环境中的应用, 发明专利, 2023, 第 1 作者, 专利号: 202310271957.9

（ 2 ） 旋转式摩擦纳米发电机, 发明专利, 2021, 第 1 作者, 专利号: CN113315406A

（ 3 ） 一种促进体内神经修复的电刺激系统, 发明专利, 2020, 第 1 作者, 专利号: CN111408046A

（ 4 ） 调节肖特基器件的肖特基势垒的方法, 发明专利, 2019, 第 6 作者, 专利号: CN110164981A

（ 5 ） 一种基于微纳米球腔阵列的单细胞定位与筛选的生物芯片及其制备方法, 发明专利, 2018, 第 4 作者, 专利号: CN108611250A

   

[1] Ruixue Wang, Shubin Chen, Yuan Bai, Shiyu Wang, Lingce Kong, Mengjie Chen, Hongqing Feng, Xiaosen Li, Zhou Li. Self-driven microplasma decontaminates chemical warfare agent simulant in different gas environments. NANO ENERGY. 2024, 第 7 作者  通讯作者  121: http://dx.doi.org/10.1016/j.nanoen.2023.109233.
[2] Li, Zhe, Wang, Engui, Zhang, Yingzi, Luo, Ruizeng, Gai, Yansong, Ouyang, Han, Deng, Yulin, Zhou, Xiaozhong, Li, Zhou, Feng, Hongqing. Antibacterial ability of black titania in dark: Via oxygen vacancies mediated electron transfer. NANO TODAY[J]. 2023, 第 10 作者  通讯作者  50: http://dx.doi.org/10.1016/j.nantod.2023.101826.
[3] Shan, Yizhu, Xu, Lingling, Cui, Xi, Wang, Engui, Jiang, Fengying, Li, Jiaxuan, Ouyang, Han, Yin, Tailang, Feng, Hongqing, Luo, Dan, Zhang, Yan, Li, Zhou. A responsive cascade drug delivery scaffold adapted to the therapeutic time window for peripheral nerve injury repair. MATERIALS HORIZONS. 2023, 第 9 作者  通讯作者  http://dx.doi.org/10.1039/d3mh01511d.
[4] Yuan Bai, Hongqing Feng, Zhou Li. Theory and applications of high-voltage triboelectric nanogenerators. CELL REPORTS PHYSICAL SCIENCE[J]. 2022, 第 2 作者  通讯作者  3(11): http://dx.doi.org/10.1016/j.xcrp.2022.101108.
[5] Sun, Yu, Chao, Shengyu, Ouyang, Han, Zhang, Weiyi, Luo, Weikang, Nie, Qingbin, Wang, Jianing, Luo, Changyi, Ni, Gongang, Zhang, Lingyu, Yang, Jun, Feng, Hongqing, Mao, Gengsheng, Li, Zhou. Hybrid nanogenerator based closed-loop self-powered low-level vagus nerve stimulation system for atrial fibrillation treatment. SCIENCE BULLETIN[J]. 2022, 第 12 作者  通讯作者  67(12): 1284-1294, 
[6] Noreen, Sehrish, Wang, Engui, Feng, Hongqing, Li, Zhou. Functionalization of TiO2 for Better Performance as Orthopedic Implants. MATERIALS. 2022, 第 3 作者  通讯作者  15(19): http://dx.doi.org/10.3390/ma15196868.
[7] Yuan Bai, Hongqing Feng, Zhou Li. Chemical Warfare Agents Decontamination via Air Mircoplasma Excited by a Triboelectric Nanogenerator. Nano Energy[J]. 2022, 第 2 作者  通讯作者  106992-106992, 
[8] Feng, Hongqing, Bai, Yuan, Qiao, Lei, Li, Zhe, Wang, Engui, Chao, Shengyu, Qu, Xuecheng, Cao, Yu, Liu, Zhuo, Han, Xi, Luo, Ruizeng, Shan, Yizhu, Li, Zhou. An Ultra-Simple Charge Supplementary Strategy for High Performance Rotary Triboelectric Nanogenerators. SMALL[J]. 2021, 第 1 作者17(29): http://dx.doi.org/10.1002/smll.202101430.
[9] Shan, Yizhu, Feng, Hongqing, Li, Zhou. Electrical Stimulation for Nervous System Injury: Research Progress and Prospects. ACTA PHYSICO-CHIMICA SINICA[J]. 2020, 第 2 作者  通讯作者  36(12): https://www.webofscience.com/wos/woscc/full-record/WOS:000607780200005.
[10] Zhao, Chaochao, Feng, Hongqing, Zhang, Lijun, Li, Zhe, Zou, Yang, Tan, Puchuan, Ouyang, Han, Jiang, Dongjie, Yu, Min, Wang, Chan, Li, Hu, Xu, Lingling, Wei, Wei, Li, Zhou. Highly Efficient In Vivo Cancer Therapy by an Implantable Magnet Triboelectric Nanogenerator. ADVANCED FUNCTIONAL MATERIALS[J]. 2019, 第 2 作者29(41): 
[11] Feng, Hongqing, Zhao, Chaochao, Tan, Puchuan, Liu, Ruping, Chen, Xin, Li, Zhou. Nanogenerator for Biomedical Applications. ADVANCED HEALTHCARE MATERIALS[J]. 2018, 第 1 作者7(10): https://www.webofscience.com/wos/woscc/full-record/WOS:000434031600005.
[12] Li, Zhe, Feng, Hongqing, Zheng, Qiang, Li, Hu, Zhao, Chaochao, Ouyang, Han, Noreen, Sehrish, Yu, Min, Su, Fan, Liu, Ruping, Li, Linlin, Wang, Zhong Lin, Li, Zhou. Photothermally tunable biodegradation of implantable triboelectric nanogenerators for tissue repairing. NANO ENERGY[J]. 2018, 第 2 作者54: 390-399, http://dx.doi.org/10.1016/j.nanoen.2018.10.020.
[13] Feng, Hongqing, Ouyang, Han, Peng, Mingzeng, Jin, Yiming, Zhang, Yalan, Liu, Zhuo, Zou, Yang, Zhao, Chaochao, Fan, Yubo, Zhai, Junyi, Wang, Zhong Lin, Li, Zhou. Assessment of extracellular matrix modulation of cell traction force by using silicon nanowire array. NANO ENERGY[J]. 2018, 第 1 作者50: 504-512, http://dx.doi.org/10.1016/j.nanoen.2018.05.057.
[14] Hongqing Feng, Wang Huaiyu. An Antibacterial Platform Based on Capacitive Carbon-Doped TiO2 Nanotubes after Charging with Direct/Alternating Currents. Nature Communications.[J]. 2018, 第 1 作者
[15] Zou, Yang, Feng, Hongqing, Ouyang, Han, Jin, Yiming, Yu, Min, Liu, Zhuo, Li, Zhou. The modulation effect of the convexity of silicon topological nanostructures on the growth of mesenchymal stem cells. RSC ADVANCES[J]. 2017, 第 2 作者7(28): 16977-16983, https://www.webofscience.com/wos/woscc/full-record/WOS:000398802000008.
[16] Tian, Jingjing, Feng, Hongqing, Yan, Ling, Yu, Min, Ouyang, Han, Li, Hu, Jiang, Wen, Jin, Yiming, Zhu, Guang, Li, Zhou, Wang, Zhong Lin. A self-powered sterilization system with both instant and sustainable antibacterial ability. NANO ENERGY[J]. 2017, 第 2 作者36: 241-249, http://dx.doi.org/10.1016/j.nanoen.2017.04.030.
[17] Wang, Guomin, Feng, Hongqing, Jin, Weihong, Gao, Ang, Peng, Xiang, Li, Wan, Wu, Hao, Li, Zhou, Chu, Paul K. Long-term antibacterial characteristics and cytocompatibility of titania nanotubes loaded with Au nanoparticles without photocatalytic effects. APPLIED SURFACE SCIENCE[J]. 2017, 第 2 作者  通讯作者  414: 230-237, http://dx.doi.org/10.1016/j.apsusc.2017.04.053.
[18] Wang, Guomin, Jin, Weihong, Qasim, Abdul Mateen, Gao, Ang, Peng, Xiang, Li, Wan, Feng, Hongqing, Chu, Paul K. Antibacterial effects of titanium embedded with silver nanoparticles based on electron-transfer-induced reactive oxygen species. BIOMATERIALS[J]. 2017, 第 7 作者  通讯作者  124: 25-34, http://dx.doi.org/10.1016/j.biomaterials.2017.01.028.
[19] Feng, Hongqing, Wang, Guomin, Jin, Weihong, Zhang, Xuming, Huang, Yifan, Gao, Ang, Wu, Hao, Wu, Guosong, Chu, Paul K. Systematic Study of Inherent Antibacterial Properties of Magnesium-based Biomaterials. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 1 作者8(15): 9662-9673, https://www.webofscience.com/wos/woscc/full-record/WOS:000374812000015.
[20] Feng, Hongqing, Wang, Guomin, Wu, Guosong, Jin, Weihong, Wu, Hao, Chu, Paul K. Plasma and ion-beam modification of metallic biomaterials for improved anti-bacterial properties. SURFACE & COATINGS TECHNOLOGY[J]. 2016, 第 1 作者306(Pt.A): 140-146, http://dx.doi.org/10.1016/j.surfcoat.2016.05.059.
[21] Wang, Guomin, Feng, Hongqing, Gao, Ang, Hao, Qi, Jin, Weihong, Peng, Xiang, Li, Wan, Wu, Guosong, Chu, Paul K. Extracellular Electron Transfer from Aerobic Bacteria to Au-Loaded TiO2 Semiconductor without Light: A New Bacteria-Killing Mechanism Other than Localized Surface Plasmon Resonance or Microbial Fuel Cells. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 第 2 作者8(37): 24509-24516, https://www.webofscience.com/wos/woscc/full-record/WOS:000384033600028.
[22] Feng, Hongqing, Zhang, Xiaolin, Wu, Guosong, Jin, Weihong, Hao, Qi, Wang, Guomin, Huang, Yifan, Chu, Paul K. Unusual anti-bacterial behavior and corrosion resistance of magnesium alloy coated with diamond-like carbon. RSC ADVANCES[J]. 2016, 第 1 作者6(18): 14756-14762, https://www.webofscience.com/wos/woscc/full-record/WOS:000369658100042.
[23] Ma, Ruonan, Feng, Hongqing, Guo, Jinsong, Liang, Yongdong, Zhang, Qian, Tian, Ying, Zhang, Jue, Fang, Jing. An Efficient and Specific Protection of Non-Thermal Plasma-Induced Live Yeast Cell Derivative (LYCD) for Cells against Plasma Damage. PLASMA PROCESSES AND POLYMERS[J]. 2014, 第 2 作者11(9): 822-832, https://www.webofscience.com/wos/woscc/full-record/WOS:000342961600002.

   

（ 1 ） 基于植入式生物能收集器件进行神经修复的方法与机制研究, 负责人, 国家任务, 2017-01--2019-12
（ 2 ） 研制植入式纳米发电机进行脊髓损伤 的自驱动电刺激治疗, 负责人, 国家任务, 2020-01--2023-12
（ 3 ） 面向颅内多参数检测的柔性颅内植入式多模态集成感知及调控技术研究, 参与, 国家任务, 2021-11--2024-10
（ 4 ） 基于电子传递的新型抗菌方法研究, 负责人, 中国科学院计划, 2022-10--2024-10
（ 5 ） 医用材料的电子传递与电控功能化研究, 负责人, 国家任务, 2024-01--2026-12

（1）电控功能化与电子传递   2023年度纳米发电机与微纳系统研讨会   2023-11-04
（2）电子传递与界面抗菌研究   2022年度材料人网生物材料技术线上研讨会   2022-09-24
（3）The anti-bacterial effects based on the electron/charge transfer between nano-interfaces   中国生物医学工程学会天津青年论坛   2018-08-02
（4）The post-charging disinfection ability of capacitive , electrodes endowed by TENG charging    2017-10-21
（5）Plasma Modification and Functionalization of Biomaterials   2015-12-08
（6）Plasma Modification and Functionalization of Biomaterials   2015-11-22
（7）Plasma-Based Surface Engineering of Metallic Orthopedic Materials and Associated Bio-Interactions    2015-08-21
（8）Plasma-Based Surface Modificatin of Metallic Orthopedic , Materials and Their Interactions with Bacteria   2015-04-10