基本信息
丁文军  男  博导  生命科学学院
电子邮件: dingwj@ucas.ac.cn
通信地址: 北京市石景山区玉泉路19号(甲)
邮政编码:

研究领域

生物化学与分子生物学、细胞生物学(Biochemistry and Molecular Biology, Cell Biology)

招生信息

   
招生专业
071010-生物化学与分子生物学
071009-细胞生物学
070202-粒子物理与原子核物理
招生方向
环境与健康、糖尿病
细胞生物学/环境与健康
核技术应用

教授课程

免疫组织化学实验
细胞生物学实验
细胞生物学技术及应用
分子细胞生物学
科研实践I
免疫组织化学实验技术
细胞生物学技术及应用讨论课
文献阅读课
细胞生物学实验技术
污染物质归趋与生态毒理学
文献阅读课(限京外所环境工程,环境科学专业的学生选修)
细胞生物学实验课
细胞生物学技术与应用讨论课
细胞生物学技术与应用
生物化学研究方法
环境毒理学研究进展
毒理学概论
细胞生物学实验技术概论

出版信息

发表论文
[1] Huawen Xu, Yang Zhao, Mingpu Shi, Zhaoqi Zhang, Wenjun Ding, Yong Zhao. Tuberous sclerosis complex 1 deficiency in macrophages promotes unclassical inflammatory response to lipopolysaccharide in vitro and dextran sodium sulfate-induced colitis in mice. Aging and Disease[J]. 2022, [2] Tengyu Zhu, Xue Chen, Huan Qiu, Yang Liu, James Mwangi, Ling Zhao, Wenjun Ding, Ren Lai, Lin Jin. Aspirin Alleviates Particulate Matter Induced Asymptomatic Orchitis of Mice via Suppression of cGAS-STING Signaling. Frontiers in Immunology[J]. 2021, 12: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673441/.
[3] 段珊珊, 王苑郦, 杨建正, 丁文军, 贺军辉. 林丹暴露诱导肝脏HepG2细胞的毒性效应研究. 中国科学院大学学报[J]. 2021, 38(6): 750-757, [4] Gao, Junling, Yuan, Juntao, Liu, Qun, Wang, Yuanli, Wang, Huiwen, Chen, Yingjie, Ding, Wenjun, Ji, Guangju, Lu, Zhongbing. Adipose-derived stem cells therapy effectively attenuates PM2.5-induced lung injury. STEM CELL RESEARCH & THERAPY[J]. 2021, 12(1): http://dx.doi.org/10.1186/s13287-021-02441-3.
[5] Zhu, TengYu, Qiu, Huan, Cao, QiQi, Duan, ZiLei, Liu, FengLiang, Song, TianZhang, Liu, Yang, Fang, YaQun, Wu, GuangMing, Zheng, YongTang, Ding, WenJun, Lai, Ren, Jin, Lin. Particulate matter exposure exacerbates susceptibility to SARS-CoV-2 infection in humanized ACE2 mice. ZOOLOGICAL RESEARCH[J]. 2021, 42(3): 335-+, http://dx.doi.org/10.24272/j.issn.2095-8137.2021.088.
[6] Liu, Zhijian, Zhuang, Wenbin, Hu, Xiaoqi, Zhao, Zhiheng, Rong, Rui, Li, Jinsong, Li, Na, Ding, Wenjun. Potential infection risk assessment of improper bioaerosol experiment operation in one BSL-3 laboratory based on the improved Wells-Riley method. BUILDING AND ENVIRONMENT[J]. 2021, 201: http://dx.doi.org/10.1016/j.buildenv.2021.107974.
[7] Zhou, Su, Xi, Yueyue, Chen, Yingying, Zhang, Zezhong, Wu, Chunyan, Yan, Wei, Luo, Aiyue, Wu, Tong, Zhang, Jinjin, Wu, Meng, Dai, Jun, Shen, Wei, Zhang, Fang, Ding, Wenjun, Wang, Shixuan. Ovarian Dysfunction Induced by Chronic Whole-Body PM2.5 Exposure. SMALL[J]. 2020, 16(33): http://dx.doi.org/10.1002/smll.202000845.
[8] Liu, Zhijian, Zhuang, Wenbin, Hu, Lingfei, Rong, Rui, Li, Jinsong, Ding, Wenjun, Li, Na. Experimental and numerical study of potential infection risks from exposure to bioaerosols in one BSL-3 laboratory. BUILDING AND ENVIRONMENT[J]. 2020, 179: 106991-106991, http://dx.doi.org/10.1016/j.buildenv.2020.106991.
[9] Han, Xiao, Liu, Hanchen, Zhang, Zezhong, Yang, Wenlan, Wu, Chunyan, Liu, Xueying, Zhang, Fang, Sun, Baofa, Zhao, Yongliang, Jiang, Guibin, Yang, YunGui, Ding, Wenjun. Epitranscriptomic 5-Methylcytosine Profile in PM2.5-induced Mouse Pulmonary Fibrosis. GENOMICS PROTEOMICS & BIOINFORMATICS[J]. 2020, 18(1): 41-51, http://lib.cqvip.com/Qikan/Article/Detail?id=00002HUHLL7G7JP0MPDO8JP1MFR.
[10] Chen, Xiaoyu, Guo, Jing, Huang, Yunlong, Liu, Shan, Huang, Ying, Zhang, Zezhong, Zhang, Fang, Lu, Zhongbing, Li, Fang, Zheng, Jialin C, Ding, Wenjun. Urban airborne PM2.5-activated microglia mediate neurotoxicity through glutaminase-containing extracellular vesicles in olfactory bulb. ENVIRONMENTAL POLLUTION[J]. 2020, 264: http://dx.doi.org/10.1016/j.envpol.2020.114716.
[11] Gao, Junling, Yuan, Juntao, Wang, Qiaoe, Lei, Tong, Shen, Xiyue, Cui, Bingqing, Zhang, Fang, Ding, Wenjun, Lu, Zhongbing. Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase alpha 2. REDOX BIOLOGY[J]. 2020, 28: https://www.webofscience.com/wos/woscc/full-record/WOS:000501490700050.
[12] Zhang, Kaiquan, Wang, Zicheng, Hu, Xiaoqi, Meng, Jiaqi, Bao, Weier, Wang, Xuefei, Ding, Wenjun, Tian, Zhiyuan. A long-wavelength turn-on fluorescent probe for intracellular nanomolar level peroxynitrite sensing with second-level response. TALANTA[J]. 2020, 219: http://dx.doi.org/10.1016/j.talanta.2020.121354.
[13] Liu, Zhijian, Zhuang, Wenbin, Hu, Xiaoqi, Zhao, Zhiheng, Rong, Rui, Ding, Wenjun, Li, Jinsong, Li, Na. Effect of equipment layout on bioaerosol temporal-spatial distribution and deposition in one BSL-3 laboratory. BUILDING AND ENVIRONMENT[J]. 2020, 181: 107149-107149, http://dx.doi.org/10.1016/j.buildenv.2020.107149.
[14] Junling Gao, Juntao Yuan, Qiaoe Wang, Tong Lei, Xiyue Shen, Bingqing Cui, Fang Zhang, Wenjun Ding, Zhongbing Lu. Metformin protects against PM2.5-induced lung injury and cardiac dysfunction independent of AMP-activated protein kinase α2. Redox Biology. 2020, 28: http://dx.doi.org/10.1016/j.redox.2019.101345.
[15] Xu, Zihan, Ding, Wenjun, Deng, Xiaobei. PM2.5, Fine Particulate Matter: A Novel Player in the Epithelial-Mesenchymal Transition?. FRONTIERS IN PHYSIOLOGYnull. 2019, 10: https://www.webofscience.com/wos/woscc/full-record/WOS:000502761800001.
[16] Yue, Wenhui, Tong, Lei, Liu, Xiaohong, Weng, Xinyu, Chen, Xiaoyu, Wang, Dongzhi, Dudley, Samuel C, Weir, E Kenneth, Ding, Wenjun, Lu, Zhongbing, Xu, Yawei, Chen, Yingjie. Short term Pm2.5 exposure caused a robust lung inflammation, vascular remodeling, and exacerbated transition from left ventricular failure to right ventricular hypertrophy. REDOX BIOLOGY[J]. 2019, 22: 101161-, http://dx.doi.org/10.1016/j.redox.2019.101161.
[17] Liu, Zhijian, Yin, Hang, Ma, Shengyuan, Jin, Gaungya, Gao, Jun, Ding, Wenjun. On-site assessments on variations of PM2.5, PM10, CO2 and TVOC concentrations in naturally ventilated underground parking garages with traffic volume. ENVIRONMENTAL POLLUTION[J]. 2019, 247: 626-637, http://dx.doi.org/10.1016/j.envpol.2019.01.095.
[18] Wang, Hongyun, Shen, Xiyue, Liu, Jingli, Wu, Chunyan, Gao, Junling, Zhang, Zezhong, Zhang, Fang, Ding, Wenjun, Lu, Zhongbing. The effect of exposure time and concentration of airborne PM2.5 on lung injury in mice: A transcriptome analysis. REDOX BIOLOGY[J]. 2019, 26: 101264-, http://dx.doi.org/10.1016/j.redox.2019.101264.
[19] Feng, Wei, Lei, Tong, Wang, Yue, Feng, Run, Yuan, Juntao, Shen, Xiyue, Wu, Yongguang, Gao, Junling, Ding, Wenjun, Lu, Zhongbing. GCN2 deficiency ameliorates cardiac dysfunction in diabetic mice by reducing lipotoxicity and oxidative stress. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2019, 130: 128-139, http://dx.doi.org/10.1016/j.freeradbiomed.2018.10.445.
[20] Tian, Guoxiong, Wang, Juan, Lu, Zhongbing, Wang, Hongyun, Zhang, Wei, Ding, Wenjun, Zhang, Fang. Indirect effect of PM1 on endothelial cells via inducing the release of respiratory inflammatory cytokines. TOXICOLOGY IN VITRO[J]. 2019, 57: 203-210, http://dx.doi.org/10.1016/j.tiv.2019.03.013.
[21] Hongyun Wang, Xiyue Shen, Guoxiong Tian, Xili Shi, Wei Huang, Yongguang Wu, Lei Sun, Can Peng, Shasha Liu, Ying Huang, Xiaoyu Chen, Fang Zhang, Yingjie Chen, Wenjun Ding, Zhongbing Lu. AMPKα2 deficiency exacerbates long-term PM2.5 exposure-induced lung injury and cardiac dysfunction. Free Radical Biology and Medicine. 2018, 121: 202-214, http://dx.doi.org/10.1016/j.freeradbiomed.2018.05.008.
[22] Han, Rui, Hu, Mingxian, Zhong, Qiang, Wan, Chong, Liu, Limin, Li, Fang, Zhang, Fang, Ding, Wenjun. Perfluorooctane sulphonate induces oxidative hepatic damage via mitochondria-dependent and NF-kappa B/TNF-alpha-mediated pathway. CHEMOSPHERE[J]. 2018, 191: 1056-1064, https://www.webofscience.com/wos/woscc/full-record/WOS:000418208000114.
[23] Wang, Hongyun, Shen, Xiyue, Tian, Guoxiong, Shi, Xili, Huang, Wei, Wu, Yongguang, Sun, Lei, Peng, Can, Liu, Shasha, Huang, Ying, Chen, Xiaoyu, Zhang, Fang, Chen, Yingjie, Ding, Wenjun, Lu, Zhongbing. AMPK alpha 2 deficiency exacerbates long-term PM2.5 exposure-induced lung injury and cardiac dysfunction. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2018, 121: 202-214, https://www.webofscience.com/wos/woscc/full-record/WOS:000433208200021.
[24] Liu, Limin, Wan, Chong, Zhang, Wei, Guan, Longfei, Tian, Guoxiong, Zhang, Fang, Ding, Wenjun. MiR-146a regulates PM1-induced inflammation via NF-kappa B signaling pathway in BEAS-2B cells. ENVIRONMENTAL TOXICOLOGY[J]. 2018, 33(7): 743-751, https://www.webofscience.com/wos/woscc/full-record/WOS:000436799900004.
[25] Han, Rui, Zhang, Fang, Wan, Chong, Liu, Limin, Zhong, Qiang, Ding, Wenjun. Effect of perfluorooctane sulphonate-induced Kupffer cell activation on hepatocyte proliferation through the NF-kappa B/TNF-alpha/IL-6-dependent pathway. CHEMOSPHERE[J]. 2018, 200: 283-294, https://www.webofscience.com/wos/woscc/full-record/WOS:000429891300032.
[26] Chen, Xiaoyu, Liu, Shan, Zhang, Wei, Wu, Chunyan, Liu, Hanchen, Zhang, Fang, Lu, Zhongbing, Ding, Wenjun. Nrf2 deficiency exacerbates PM2.5-induced olfactory bulb injury. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2018, 505(4): 1154-1160, http://dx.doi.org/10.1016/j.bbrc.2018.10.057.
[27] Rui Han, Mingxian Hu, Qiang Zhong, Chong Wan, Limin Liu, Fang Li, Fang Zhang, Wenjun Ding. Perfluorooctane sulphonate induces oxidative hepatic damage via mitochondria-dependent and NF-κB/TNF-α-mediated pathway. Chemosphere. 2018, 191: 1056-1064, http://dx.doi.org/10.1016/j.chemosphere.2017.08.070.
[28] Rui Han, Fang Zhang, Chong Wan, Limin Liu, Qiang Zhong, Wenjun Ding. Effect of perfluorooctane sulphonate-induced Kupffer cell activation on hepatocyte proliferation through the NF-κB/TNF-α/IL-6-dependent pathway. Chemosphere. 2018, 200: 283-294, http://dx.doi.org/10.1016/j.chemosphere.2018.02.137.
[29] Huang, Ying, Liu, Fang, Zhang, Fang, Liu, Pingsheng, Xu, Tao, Ding, Wenjun. Vanadium(IV)-chlorodipicolinate alleviates hepatic lipid accumulation by inducing autophagy via the LKB1/AMPK signaling pathway in vitro and in vivo. JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2018, 183: 66-76, http://dx.doi.org/10.1016/j.jinorgbio.2018.03.006.
[30] Xiaobei Deng, Nannan Feng, Min Zheng, Xiaofei Ye, Hongyan Lin, Xiao Yu, Zhihua Gan, Zheng Fang, Huan Zhang, Ming Gao, Zhi-jie Zheng, Herbert Yu, Wenjun Ding, Biyun Qian. PM2.5 exposure-induced autophagy is mediated by lncRNA loc146880 which also promotes the migration and invasion of lung cancer cells. BBA - General Subjects. 2017, 1861(2): 112-125, http://dx.doi.org/10.1016/j.bbagen.2016.11.009.
[31] Xu, Jinxia, Zhang, Wei, Lu, Zhongbing, Zhang, Fang, Ding, Wenjun. Airborne PM2.5-Induced Hepatic Insulin Resistance by Nrf2/JNK-Mediated Signaling Pathway. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH[J]. 2017, 14(7): https://doaj.org/article/8cfb36d525fb4313a75912b34d4ebae4.
[32] Zhao, Qingjie, Chu, Zhulang, Zhu, Linnan, Yang, Tao, Wang, Peng, Liu, Fang, Huang, Ying, Zhang, Fang, Zhang, Xiaodong, Ding, Wenjun, Zhao, Yong. 2-Deoxy-d-glucose Treatment Decreases anti-inflammatory M2 Macrophage Polarization in Mice with Tumor and allergic airway inflammation. FRONTIERS IN IMMUNOLOGY[J]. 2017, 8: https://doaj.org/article/61e190be9546403a95b56fffc5e5736a.
[33] Li, Junhui, Chen, Shuqiu, Xiao, Xiang, Zhao, Yong, Ding, Wenjun, Li, Xian C. IL-9 and Th9 cells in health and diseases-From tolerance to immunopathology. CYTOKINE & GROWTH FACTOR REVIEWSnull. 2017, 37: 47-55, http://dx.doi.org/10.1016/j.cytogfr.2017.07.004.
[34] Deng, Xiaobei, Feng, Nannan, Zheng, Min, Ye, Xiaofei, Lin, Hongyan, Yu, Xiao, Gan, Zhihua, Fang, Zheng, Zhang, Huan, Gao, Ming, Zheng, Zhijie, Yu, Herbert, Ding, Wenjun, Qian, Biyun. PM2.5 exposure-induced autophagy is mediated by lncRNA loc146880 which also promotes the migration and invasion of lung cancer cells. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS[J]. 2017, 1861(2): 112-125, http://dx.doi.org/10.1016/j.bbagen.2016.11.009.
[35] Rui, Wei, Guan, Longfei, Zhang, Fang, Zhang, Wei, Ding, Wenjun. PM2.5-induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF-kappa B-dependent pathway. JOURNAL OF APPLIED TOXICOLOGY[J]. 2016, 36(1): 48-59, https://www.webofscience.com/wos/woscc/full-record/WOS:000365795900005.
[36] Yang, Tao, Zhu, Linnan, Zhai, Yanhua, Zhao, Qingjie, Peng, Jianxia, Zhang, Hongbing, Yang, Zhongzhou, Zhang, Lianfeng, Ding, Wenjun, Zhao, Yong. TSC1 controls IL-1 beta expression in macrophages via mTORC1-dependent C/EBP beta pathway. CELLULAR & MOLECULAR IMMUNOLOGY[J]. 2016, 13(5): 640-650, https://www.webofscience.com/wos/woscc/full-record/WOS:000387973600009.
[37] Zhang LuYao, Zhang Wei, Zhang Fang, Ding WenJun. Effects of Protein Corona on Intracellular Uptake and Cytotoxicity of PM1. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICSnull. 2016, 43(6): 624-626, [38] Ding, Wenjun, Ghio, Andrew J, Wu, Weidong. Preface: Special Issue on Air Pollution. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTSnull. 2016, 1860(12): 2769-2770, http://dx.doi.org/10.1016/j.bbagen.2016.09.007.
[39] Qingjie Zhao, Hui Chen, Tao Yang, Wei Rui, Fang Liu, Fang Zhang, Yong Zhao, Wenjun Ding. Direct effects of airborne PM2.5 exposure on macrophage polarizations. BBA - General Subjects. 2016, 1860(12): 2835-2843, http://dx.doi.org/10.1016/j.bbagen.2016.03.033.
[40] Zhang, Liang, Huang, Ying, Liu, Fang, Zhang, Fang, Ding, Wenjun. Vanadium(IV)-chlorodipicolinate inhibits 3T3-L1 preadipocyte adipogenesis by activating LKB1/AMPK signaling pathway. JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2016, 162: 1-8, http://dx.doi.org/10.1016/j.jinorgbio.2016.06.013.
[41] Wan, Chong, Han, Rui, Liu, Limin, Zhang, Fang, Li, Fang, Xiang, Mingdeng, Ding, Wenjun. Role of miR-155 in fluorooctane sulfonate-induced oxidative hepatic damage via the Nrf2-dependent pathway. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2016, 295: 85-93, http://dx.doi.org/10.1016/j.taap.2016.01.023.
[42] Bai, Ru, Guan, Longfei, Zhang, Wei, Xu, Jinxia, Rui, Wei, Zhang, Fang, Ding, Wenjun. Comparative study of the effects of PM1-induced oxidative stress on autophagy and surfactant protein B and C expressions in lung alveolar type II epithelial MLE-12 cells. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS[J]. 2016, 1860(12): 2782-2792, http://dx.doi.org/10.1016/j.bbagen.2016.05.020.
[43] Tao Yang, Linnan Zhu, Yanhua Zhai, Qingjie Zhao, Jianxia Peng, Hongbing Zhang, Zhongzhou Yang, Lianfeng Zhang, Wenjun Ding, Yong Zhao. TSC1 controls IL-1β expression in macrophages via mTORCl-dependent C/EBPβ pathway. 中国免疫学杂志:英文版. 2016, 13(5): 640-650, http://lib.cqvip.com/Qikan/Article/Detail?id=670093834.
[44] Hongyun Wang, Yuting Guo, Limin Liu, Longfei Guan, Ting Wang, Luyao Zhang, Yue Wang, Jianwei Cao, Wenjun Ding, Fang Zhang, Zhongbing Lu. DDAH1 plays dual roles in PM2.5 induced cell death in A549 cells. BBA - General Subjects. 2016, 1860(12): 2793-2801, http://dx.doi.org/10.1016/j.bbagen.2016.03.022.
[45] Zhang LuYao, Zhang Wei, Zhang Fang, Ding WenJun. Effects of Protein Corona on Intracellular Uptake and Cytotoxicity of PM1. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICSnull. 2016, 43(6): 624-626, [46] Yang Tao, Zhu Linnan, Zhai Yanhua, Zhao Qingjie, Peng Jianxia, Zhang Hongbing, Yang Zhongzhou, Zhang Lianfeng, Ding Wenjun, Zhao Yong. TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPb pathway. Cellular & Molecular Immunology[J]. 2016, 13(5): 640-650, [47] Wang, Hongyun, Guo, Yuting, Liu, Limin, Guan, Longfei, Wang, Ting, Zhang, Luyao, Wang, Yue, Cao, Jianwei, Ding, Wenjun, Zhang, Fang, Lu, Zhongbing. DDAH1 plays dual roles in PM2.5 induced cell death in A549 cells. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS[J]. 2016, 1860(12): 2793-2801, http://dx.doi.org/10.1016/j.bbagen.2016.03.022.
[48] Ru Bai, Longfei Guan, Wei Zhang, Jinxia Xu, Wei Rui, Fang Zhang, Wenjun Ding. Comparative study of the effects of PM1-induced oxidative stress on autophagy and surfactant protein B and C expressions in lung alveolar type II epithelial MLE-12 cells. BBA - General Subjects. 2016, 1860(12): 2782-2792, http://dx.doi.org/10.1016/j.bbagen.2016.05.020.
[49] Zhao, Qingjie, Chen, Hui, Yang, Tao, Rui, Wei, Liu, Fang, Zhang, Fang, Zhao, Yong, Ding, Wenjun. Direct effects of airborne PM2.5 exposure on macrophage polarizations. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS[J]. 2016, 1860(12): 2835-2843, http://dx.doi.org/10.1016/j.bbagen.2016.03.033.
[50] Guan, Longfei, Rui, Wei, Bai, Ru, Zhang, Wei, Zhang, Fang, Ding, Wenjun. Effects of Size-Fractionated Particulate Matter on Cellular Oxidant Radical Generation in Human Bronchial Epithelial BEAS-2B Cells. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH[J]. 2016, 13(5): https://doaj.org/article/8eee39e3934643349bf10ed06da412a0.
[51] Zhu, Linnan, Zhao, Qingjie, Yang, Tao, Ding, Wenjun, Zhao, Yong. Cellular Metabolism and Macrophage Functional Polarization. INTERNATIONAL REVIEWS OF IMMUNOLOGYnull. 2015, 34(1): 82-100, https://www.webofscience.com/wos/woscc/full-record/WOS:000347971900007.
[52] Liu, Fang, Huang, Yunlong, Zhang, Fang, Chen, Qiang, Wu, Beiqing, Rui, Wei, Zheng, Jialin C, Ding, Wenjun. Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase-mediated glutamate generation. JOURNAL OF NEUROCHEMISTRY[J]. 2015, 134(2): 315-326, [53] Zhao, Qian, Chen, Deliang, Liu, Pingsheng, Wei, Taotao, Zhang, Fang, Ding, Wenjun. Oxidovanadium(IV) sulfate-induced glucose uptake in HepG2 cells through IR/Akt pathway and hydroxyl radicals. JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2015, 149: 39-44, http://dx.doi.org/10.1016/j.jinorgbio.2015.05.005.
[54] Li, Runkui, Li, Zhipeng, Gao, Wenju, Ding, Wenjun, Xu, Qun, Song, Xianfeng. Diurnal, seasonal, and spatial variation of PM2.5 in Beijing. SCIENCE BULLETIN[J]. 2015, 60(3): 387-395, http://dx.doi.org/10.1007/s11434-014-0607-9.
[55] Yi, Shuo, Zhang, Fang, Qu, Fang, Ding, Wenjun. Water-Insoluble Fraction of Airborne Particulate Matter (PM10) Induces Oxidative Stress in Human Lung Epithelial A549 Cells. ENVIRONMENTAL TOXICOLOGY[J]. 2014, 29(2): 226-233, https://www.webofscience.com/wos/woscc/full-record/WOS:000328936900011.
[56] Wang, Jieting, Deng, Xiaobei, Zhang, Fang, Chen, Deliang, Ding, Wenjun. ZnO nanoparticle-induced oxidative stress triggers apoptosis by activating JNK signaling pathway in cultured primary astrocytes. NANOSCALE RESEARCH LETTERS[J]. 2014, 9(1): http://www.corc.org.cn/handle/1471x/2374281.
[57] Zhang, Junxian, Zheng, Li, Zhu, Donglin, An, Huiru, Yang, Yourong, Liang, Yan, Zhao, Weiguo, Ding, Wenjun, Wu, Xueqiong. Polymorphisms in the Interleukin 18 Receptor 1 Gene and Tuberculosis Susceptibility among Chinese. PLOS ONE[J]. 2014, 9(10): https://doaj.org/article/7180120399b049c0a588fabba50074c8.
[58] Deng, Xiaobei, Zhang, Fang, Wang, Lijuan, Rui, Wei, Long, Fang, Zhao, Yong, Chen, Deliang, Ding, Wenjun. Airborne fine particulate matter induces multiple cell death pathways in human lung epithelial cells. APOPTOSIS[J]. 2014, 19(7): 1099-1112, https://www.webofscience.com/wos/woscc/full-record/WOS:000336925400004.
[59] Meng, Xiangying, Suo, Xingmei, Ding, Wenjun, Li, Xiangjun, Ding, Yongsheng. Determination of 8-hydroxy-2 '-deoxyguanosine derivatized with 4-chloro-7-nitrobenzofurazan in urine by CE-LIF. ELECTROPHORESIS[J]. 2014, 35(12-13): 1873-1879, https://www.webofscience.com/wos/woscc/full-record/WOS:000339015000016.
[60] Xie, Mingxia, Chen, Deliang, Zhang, Fang, Willsky, Gail R, Crans, Debbie C, Ding, Wenjun. Effects of vanadium (III, IV, V)-chlorodipicolinate on glycolysis and antioxidant status in the liver of STZ-induced diabetic rats. JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2014, 136: 47-56, http://dx.doi.org/10.1016/j.jinorgbio.2014.03.011.
[61] Liu, Fang, Xie, Mingxia, Chen, Deliang, Li, Jian, Ding, Wenjun. Effect of (VO)-O-IV(dipic-Cl)(H2O)(2) on Lipid Metabolism Disorders in the Liver of STZ-Induced Diabetic Rats. JOURNAL OF DIABETES RESEARCH[J]. 2013, 2013: https://www.webofscience.com/wos/woscc/full-record/WOS:000318641000001.
[62] Deng, Xiaobei, Rui, Wei, Zhang, Fang, Ding, Wenjun. PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells. CELL BIOLOGY AND TOXICOLOGY[J]. 2013, 29(3): 143-157, https://www.webofscience.com/wos/woscc/full-record/WOS:000319082000002.
[63] Deng, Xiaobei, Zhang, Fang, Rui, Wei, Long, Fang, Wang, Lijuan, Feng, Zhaohan, Chen, Deliang, Ding, Wenjun. PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells. TOXICOLOGY IN VITRO[J]. 2013, 27(6): 1762-1770, http://dx.doi.org/10.1016/j.tiv.2013.05.004.
[64] 杜明艳, 丁文军, 封靖, 杜会山. 血管紧张素转化酶基因I/D多态性与脑梗死后抑郁相关. 基础医学与临床[J]. 2012, 32(9): 1040-1043, http://lib.cqvip.com/Qikan/Article/Detail?id=42912882.
[65] 贺擎, 丁文军, 芮魏, 张芳. 冬季和夏季PM_(10)和PM_(2.5)对人肺上皮细胞A549毒性的比较. 中国科学院研究生院学报[J]. 2012, 29(3): 324-331, http://lib.cqvip.com/Qikan/Article/Detail?id=41878196.
[66] Zhen, Yu, Sun, Lina, Liu, He, Duan, Kaizhong, Zeng, Chun, Zhang, Lianjun, Jin, Di, Peng, Jianxia, Ding, Wenjun, Zhao, Yong. Alterations of peripheral CD4(+)CD25(+)Foxp3(+) T regulatory cells in mice with STZ-induced diabetes. CELLULAR & MOLECULAR IMMUNOLOGY[J]. 2012, 9(1): 75-85, https://www.webofscience.com/wos/woscc/full-record/WOS:000299201200013.
[67] Sun, Chenming, Sun, Lina, Ma, Haixia, Peng, Jianxia, Zhen, Yu, Duan, Kaizhong, Liu, Guangwei, Ding, Wenjun, Zhao, Yong. The phenotype and functional alterations of macrophages in mice with hyperglycemia for long term. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2012, 227(4): 1670-1679, https://www.webofscience.com/wos/woscc/full-record/WOS:000298986100044.
[68] Zeng, Chun, Shi, Xiaoyun, Zhang, Baojun, Liu, He, Zhang, Lianjun, Ding, Wenjun, Zhao, Yong. The imbalance of Th17/Th1/Tregs in patients with type 2 diabetes: relationship with metabolic factors and complications. JOURNAL OF MOLECULAR MEDICINE-JMM[J]. 2012, 90(2): 175-186, https://www.webofscience.com/wos/woscc/full-record/WOS:000302135400008.
[69] 段树民. CXCL12 enhances human neural progenitor cell survival through a CXCR7- and CXCR4-mediated endocytotic signaling pathway. Stem Cells[J]. 2012, 30(11): 2571-2583, [70] Wei, Han, Wei, Dan, Yi, Shuo, Zhang, Fang, Ding, Wenjun. Oxidative stress induced by urban fine particles in cultured EA.hy926 cells. HUMAN & EXPERIMENTAL TOXICOLOGY[J]. 2011, 30(7): 579-590, https://www.webofscience.com/wos/woscc/full-record/WOS:000291891200008.
[71] 杜明艳, 封靖, 杜会山, 丁文军. ACE、AGT基因联合多态性与高血压合并脑梗塞相关. 基础医学与临床[J]. 2011, 31(11): 1189-1193, http://lib.cqvip.com/Qikan/Article/Detail?id=39860084.
[72] 杜明艳, 杜会山, 周桔, 丁文军. 血管紧张素原基因CD235Met-Thr变异与高血压脑梗塞发病的相关性. 中国科学院研究生院学报[J]. 2010, 27(1): 133-137, http://lib.cqvip.com/Qikan/Article/Detail?id=33193730.
[73] Zhang, Yu, Sun, Lei, Jiang, Jian, Zhang, Xiaolin, Ding, Wenjun, Gan, Zhihua. Biodegradation-induced surface change of polymer microspheres and its influence on cell growth. POLYMER DEGRADATION AND STABILITY[J]. 2010, 95(8): 1356-1364, http://dx.doi.org/10.1016/j.polymdegradstab.2010.01.025.
[74] 杜明艳, 封靖, 周桔, 丁文军. 血管紧张素转化酶基因I/D多态性与高血压脑梗塞发病的相关性. 中国科学院研究生院学报[J]. 2010, 27(6): 778-781, http://lib.cqvip.com/Qikan/Article/Detail?id=36104143.
[75] Liu, Yang, Tian, Weixi, Ma, Xiaofeng, Ding, Wenjun. Evaluation of inhibition of fatty acid synthase by ursolic acid: Positive cooperation mechanism. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2010, 392(3): 386-390, https://www.webofscience.com/wos/woscc/full-record/WOS:000275019800025.
[76] Wang, Lijuan, Wang, Lin, Ding, Wenjun, Zhang, Fang. Acute Toxicity of Ferric Oxide and Zinc Oxide Nanoparticles in Rats. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY[J]. 2010, 10(12): 8617-8624, http://www.corc.org.cn/handle/1471x/2412883.
[77] 曲凡, 丁文军, 伊硕, 张芳. PM2.5对肺泡Ⅱ型上皮细胞MLE-12的毒性研究. 毒理学杂志[J]. 2010, 19-23, http://lib.cqvip.com/Qikan/Article/Detail?id=34052537.
[78] 徐蓓蓓, 杜明艳, 万冲, 于云江, 张芳, 郑莉, 周桔, 丁文军. 全氟辛烷磺酸对SD大鼠肝毒性及其肝脏细胞色素P450 mRNA表达的影响. 毒理学杂志[J]. 2010, 24(6): 456-460, http://lib.cqvip.com/Qikan/Article/Detail?id=37478286.
[79] Xue, Jianfeng, Ding, Wenjun, Liu, Yan. Anti-diabetic effects of emodin involved in the activation of PPAR gamma on high-fat diet-fed and low dose of streptozotocin-induced diabetic mice. FITOTERAPIA[J]. 2010, 81(3): 173-177, http://ir.xjlas.org/handle/365004/9980.
[80] 丁文军, 丁文军, 周桔, 彭端, 李明. 钒化合物抗糖尿病作用的研究进展. 化学进展[J]. 2009, 896-902, http://lib.cqvip.com/Qikan/Article/Detail?id=30293466.
[81] Li, Ming, Ding, Wenjun, Smee, Jason J, Baruah, Bharat, Willsky, Gail R, Crans, Debbie C. Anti-diabetic effects of vanadium(III, IV, V)-chlorodipicolinate complexes in streptozotocin-induced diabetic rats. BIOMETALS[J]. 2009, 22(6): 895-905, http://www.corc.org.cn/handle/1471x/2401831.
[82] Wei Dan, Ding Wenjun, Zhou Ju, Peng Duan, Li Ming. Research Progress in Anti-Diabetic Effects of Vanadium Compounds. PROGRESS IN CHEMISTRY[J]. 2009, 21(5): 896-902, http://www.corc.org.cn/handle/1471x/2399508.
[83] Smee, Jason J, Epps, Jason A, Ooms, Kristopher, Bolte, Stephanie E, Polenova, Tatyana, Baruah, Bharat, Yang, Luqin, Ding, Wenjun, Li, Ming, Willsky, Gail R, la Cour, Agnete, Anderson, Oren P, Crans, Debbie C. Chloro-substituted dipicolinate vanadium complexes: Synthesis, solution, solid-state, and insulin-enhancing properties. JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2009, 103(4): 575-584, http://www.corc.org.cn/handle/1471x/2393788.
[84] Li, Ming, Smee, Jason J, Ding, Wenjun, Crans, Debbie C. Anti-diabetic effects of sodium 4-amino-2,6-dipicolinatodioxovanadium(V) dihydrate in streptozotocin-induced diabetic rats. JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2009, 103(4): 585-589, http://www.corc.org.cn/handle/1471x/2405179.
[85] 赵剑宇, 丁文军, 张芳. 基于代谢组学方法研究纳米二氧化钛对大鼠肾功能的影响. 毒理学杂志[J]. 2009, 23(3): 201-204, http://lib.cqvip.com/Qikan/Article/Detail?id=30849983.
[86] Li, Ming, Tay, Aydin, Beutner, Gisela, Ding, Wenjun, Sheu, SheyShing, Bidasee, Keshore. Increased Levels Of Type 2 Ryanodine Receptor (RyR2) In Rat Heart Mitochondria During Diabetes. BIOPHYSICAL JOURNALnull. 2009, 96(3): 114A-114A, [87] 王琳, 王莉娟, 张芳, 丁文军. 纳米氧化锌对人肺腺癌细胞A549的毒性. 中国科学院研究生院学报[J]. 2009, 26(1): 83-90, http://lib.cqvip.com/Qikan/Article/Detail?id=29778028.
[88] Shi, Xudong, Sun, Lei, Jiang, Jian, Zhang, Xiaolin, Ding, Wenjun, Gan, Zhihua. Biodegradable Polymeric Microcarriers with Controllable Porous Structure for Tissue Engineering. MACROMOLECULAR BIOSCIENCE[J]. 2009, 9(12): 1211-1218, http://www.corc.org.cn/handle/1471x/2402270.
[89] Chen, Guanmin, Fei, Liping, Ding, Wenjun. The association of psychological symptoms with unintentional injuries among retired employees of a university in China. INTERNATIONAL JOURNAL OF INJURY CONTROL AND SAFETY PROMOTION[J]. 2008, 15(3): 157-163, http://www.corc.org.cn/handle/1471x/2388459.
[90] 周桔, 彭端, 李明, 丁文军. 钒对遗传性Ⅱ型糖尿病KK小鼠降糖作用的实验研究. 中国科学院研究生院学报[J]. 2008, 25(2): 192-196, http://lib.cqvip.com/Qikan/Article/Detail?id=26756185.
[91] Li, Ming, Ding, Wenjun, Baruah, Bharat, Crans, Debbie C, Wang, Ruilin. Inhibition of protein tyrosine phosphatase 1B and alkaline phosphatase by bis(maltolato)oxovanadium (IV). JOURNAL OF INORGANIC BIOCHEMISTRY[J]. 2008, 102(10): 1846-1853, http://dx.doi.org/10.1016/j.jinorgbio.2008.06.007.
[92] Ma, Haixia, Liu, Guangwei, Ding, Wenjun, Wu, You, Cai, Lu, Zhao, Yong. Diabetes-induced alteration of F4/80(+) macrophages: a study in mice with streptozotocin-induced diabetes for a long term. JOURNAL OF MOLECULAR MEDICINE-JMM[J]. 2008, 86(4): 391-400, https://www.webofscience.com/wos/woscc/full-record/WOS:000255093600005.
[93] Zhang, Xiaolin, Fei, Yurong, Zhang, Min, Wei, Dan, Li, Ming, Ding, Wenjun, Yang, Jianhong. Reversal of osteoporotic changes of mineral composition in femurs of diabetic rats by insulin. BIOLOGICAL TRACE ELEMENT RESEARCH[J]. 2008, 121(3): 233-242, http://www.corc.org.cn/handle/1471x/2389455.
[94] Li, Ming, Wei, Dan, Ding, Wenjun, Baruah, Bharat, Crans, Debbie C. Anti-diabetic effects of cesium aqua (N,N '-ethylene(salicylideneiminato)-5-sulfonato) oxovanadium (IV) dihydrate in streptozotocin-induced diabetic rats. BIOLOGICAL TRACE ELEMENT RESEARCH[J]. 2008, 121(3): 226-232, http://www.corc.org.cn/handle/1471x/2390785.
[95] 张敏, 李明, 费聿荣, 杨建虹, 丁文军. 口服富铬啤酒酵母对链脲佐霉素诱导糖尿病大鼠的生物效应. 中国科学院研究生院学报[J]. 2007, 24(2): 223-228, http://lib.cqvip.com/Qikan/Article/Detail?id=24230033.
[96] 费聿荣, 韦丹, 李明, 张敏, 张晓琳, 丁文军, 杨建虹. STZ诱导的糖尿病对骨密度和血清睾酮的影响. 中国科学院研究生院学报. 2007, 24(2): 217-222, http://lib.cqvip.com/Qikan/Article/Detail?id=24230032.
[97] Wei, Dan, Li, Ming, Ding, Wenjun. Effect of vanadate on gene expression of the insulin signaling pathway in skeletal muscle of streptozotocin-induced diabetic rats. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY[J]. 2007, 12(8): 1265-1273, http://www.corc.org.cn/handle/1471x/2382801.
[98] 李明, 张敏, 丁文军. 4-氯-2,6-双吡啶双氧钒化合物降低1型糖尿病大鼠血糖的生物学作用. 中国科学院研究生院学报[J]. 2007, 24(4): 460-464, http://lib.cqvip.com/Qikan/Article/Detail?id=25310438.
[99] Fei, Yurong, Zhang, Min, Li, Ming, Huang, Yuying, He, Wei, Ding, Wenjun, Yang, Jianhong. Element analysis in femur of diabetic osteoporosis model by SRXRF microprobe. MICRONnull. 2007, 38(6): 637-642, http://dx.doi.org/10.1016/j.micron.2006.09.003.
[100] 王莉娟, 丁文军. 纳米毒理研究进展. 中国药理学与毒理学杂志[J]. 2007, 21(1): 77-80, http://lib.cqvip.com/Qikan/Article/Detail?id=23818848.
发表著作
(1) 国家污染物环境健康风险名录-化学第一分册, Directory of National Environment and Health: Chemical Pollutant Part I, 中国环境科学出版社, 2009-02, 第 1 作者
(2) Comprhensive Handbook of Iodine, Oxford: Academic Press, 2009-11, 
(3) 国内外化学污染物环境与健康风险排序比较研究, Overview of Risk Assessment for Chemcial Pollution and Human Health in the World , 科学出版社, 2010-09, 第 2 作者
(4) 国家污染物环境健康风险名录(化学第二分册), Directory of National Environment and Heath: Chemical Pollutant II, 中国环境科学出版社, 2011-08, 第 1 作者
(5) 有毒生物, 人民卫生出版社, 2013-11, 第 3 作者
(6) 国家污染物环境健康风险名录(生物分册), Directory of National Environment and Heath: Biological Pollutant, 中国环境科学出版社 , 2013-12, 第 1 作者
(7) 营养组学, Nutriomics, 中国协和医科大学出版社, 2015-11, 第 3 作者
(8) Nanomaterials in Energy and Environmental Applications, Pan Stanford Publishing Pte. Ltd, 2016-10, 第 1 作者

科研活动

   

合作情况

   
项目协作单位

中国科学院理化技术研究所、中国科学院生态环境研究中心、中国科学院动物所、中国环境科学研究院、中国疾病控制与预防中心、中国医科院基础医学研究所、中国科学院高能物理研究所、中国科学院化学所、美国科罗拉多州立大学、日本理化学研究所、日本山梨县环境科学研究所、美国内布拉斯加大学医学中心