丁奎岭-中国科学院大学-UCAS

基本信息

丁奎岭男博导中国科学院上海有机化学研究所
电子邮件： kding@sioc.ac.cn
通信地址：上海市零陵路345号
邮政编码： 200032

研究领域

新型手性配体的设计、合成及应用

组合不对称催化

手性催化剂负载化新方法

一氧化碳和二氧化碳的绿色转化

招生信息

招生专业

070303-有机化学

招生方向

均相催化，手性合成

教育背景

1993-09--1994-09   日本龙谷大学理学部   博士后
1987-09--1990-10   南京大学化学系   博士
1985-09--1987-06   郑州大学   硕士研究生
1981-09--1985-06   郑州大学化学系   本科

学历

研究生学历

学位

研究生博士学位

教授课程

高等有机化学
物理有机化学

专利与奖励

奖励信息

（1） Humboldt Research Award, 其他, 2016
（2） Yoshida Prize, , 其他, 2015
（3）中国化学会黄耀曾金属有机化学奖, , 其他, 2014
（4）全国优秀科技工作者, , 部委级, 2014
（5）十佳全国优秀科技工作者提名奖, , 部委级, 2014
（6）上海市优秀科研院所长奖, , 市地级, 2013
（7）上海市自然科学牡丹奖, , 省级, 2010
（8）基于组合方法与组装策略的新型手, 二等奖, 国家级, 2009
（9）基于组合方法与组装策略的新型手, 一等奖, 省级, 2008

专利成果

（ 1 ）过渡金属络合物、合成方法及其用途, 发明, 2007, 第 1 作者, 专利号: ZL 200510023632.0
（ 2 ）桥连双希夫碱钴络合物、合成方法和应用, 发明, 2012, 第 1 作者, 专利号: ZL2010102889 69.5
（ 3 ）桥连双希夫碱钛络合物及其合成及其应用, 发明, 2010, 第 1 作者, 专利号: 201010154458.4
（ 4 ）螺环骨架膦噁唑啉配体、合成方法及其在不对称氢化反应中的应用, 发明, 2009, 第 1 作者, 专利号: 200910051314.3
（ 5 ）一种手性环氧氯丙烷的制备方法, 发明, 2007, 第 1 作者, 专利号: ZL200510023852.3
（ 6 ）双核金属络合物的合成及其催化的二氧化碳和环氧化合物的共聚合和环加成反应, 发明, 2008, 第 1 作者, 专利号: ZL200510110419.3
（ 7 ）联萘酚骨架的取代双齿亚磷酰胺配体在烯烃氢甲酰化反应中的应用, 发明, 2008, 第 1 作者, 专利号: ZL200610027493.3
（ 8 ）制备二异松蒎基氯甲硼烷的方法, 发明, 2011, 第 2 作者, 专利号: ZL200710036536.9
（ 9 ）手性单磷配体、合成方法及其用途, 发明, 2009, 第 1 作者, 专利号: ZL200410066892.1
（ 10 ）一类手性有机-无机高分子组装体催化剂、合成方法及其用途, 发明, 2007, 第 1 作者, 专利号: ZL 200410053352.X
（ 11 ）含有C2对称骨架单膦配体、合成方法及其用途, 发明, 2007, 第 1 作者, 专利号: ZL 200410084658.1
（ 12 ）螺环骨架膦噁唑啉配体、合成方法及其在不对称氢化反应中的应用, 发明, 2012, 第 1 作者, 专利号: ZL200910051314.3
（ 13 ）螺缩酮骨架的取代双齿膦配体在烯烃氢甲酰化反应中的应用, 发明, 2012, 第 1 作者, 专利号: 201210243736.2
（ 14 ）手性芳香螺缩酮类化合物及其制备方法和应用,中国发明专利, 发明, 2012, 第 1 作者, 专利号: 201210253476.7
（ 15 ）一种依泽替米贝的合成方法及该方法中所用的中间体,中国发明专利, 发明, 2012, 第 1 作者, 专利号: 201210253879.1
（ 16 ）一种丙烯氢甲酰化催化体系和方法, 发明, 2012, 第 1 作者, 专利号: ZL200610147735.2
（ 17 ）一种手性α-亚甲基β-内酰胺类化合物及其制备方法和应用, 发明, 2012, 第 1 作者, 专利号: 201210253862.6
（ 18 ）新型钌络合物及制备甲醇和二醇的方法, 发明, 2012, 第 1 作者, 专利号: 201210403332.5
（ 19 ）手性芳香螺缩酮骨架双膦配体及其制备方法和应用，中国发明专利, 发明, 2012, 第 1 作者, 专利号: 201210253896.5

出版信息

发表论文

[1] Zhang, Di, Xiong, Youyuan, Guo, Yingjie, Zhang, Lei, Wang, Zheng, Ding, Kuiling. Palladium-Catalyzed Enantioselective Intramolecular Heck Carbonylation Reactions: Asymmetric Synthesis of 2-Oxindole Ynones and Carboxylic Acids. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2022, 第 6 作者  通讯作者  28(1): http://dx.doi.org/10.1002/chem.202103670.
[2] Tang, Hairong, Liang, Yuru, Cheng, Jiayi, Ding, Kuiling, Wang, Yang. Bifunctional chiral selenium-containing 1,4-diarylazetidin-2-ones with potent antitumor activities by disrupting tubulin polymerization and inducing reactive oxygen species production. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2021, 第 4 作者  通讯作者  221: http://dx.doi.org/10.1016/j.ejmech.2021.113531.
[3] Fan, Chao, Hou, Jing, Chen, YuJia, Ding, KuiLing, Zhou, QiLin. Rhodium-Catalyzed Regioselective Hydroformylation of Alkynes to alpha,beta-Unsaturated Aldehydes Using Formic Acid. ORGANIC LETTERS[J]. 2021, 第 4 作者  通讯作者  23(6): 2074-2077, http://dx.doi.org/10.1021/acs.orglett.1c00234.
[4] Wang, Chengdong, Guo, Yingjie, Wang, Xiaoming, Wang, Zheng, Ding, Kuiling. Ni-Catalyzed Regioselective Hydroarylation of 1-Aryl-1,3-Butadienes with Aryl Halides. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2021, 第 5 作者  通讯作者  27(64): 15903-15907, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000702465500001.
[5] Wang, Xiaoming, Han, Zhaobin, Wang, Zheng, Ding, Kuiling. A Type of Structurally Adaptable Aromatic Spiroketal Based Chiral Diphosphine Ligands in Asymmetric Catalysis. ACCOUNTS OF CHEMICAL RESEARCH. 2021, 第 4 作者  通讯作者  54(3): 668-684, http://dx.doi.org/10.1021/acs.accounts.0c00697.
[6] Tang, Hairong, Liang, Yuru, Cheng, Jiayi, Ding, Kuiling, Wang, Yang. Bifunctional chiral selenium-containing 1,4-diarylazetidin-2-ones with potent antitumor activities by disrupting tubulin polymerization and inducing reactive oxygen species production. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2021, 第 11 作者221: http://dx.doi.org/10.1016/j.ejmech.2021.113531.
[7] Zhang, Di, Xiong, Youyuan, Guo, Yingjie, Zhang, Lei, Wang, Zheng, Ding, Kuiling. Palladium-Catalyzed Enantioselective Intramolecular Heck Carbonylation Reactions: Asymmetric Synthesis of 2-Oxindole Ynones and Carboxylic Acids. CHEMISTRY-A EUROPEAN JOURNAL. 2021, 第 11 作者
[8] Fan, Chao, Hou, Jing, Chen, YuJia, Ding, KuiLing, Zhou, QiLin. Rhodium-Catalyzed Regioselective Hydroformylation of Alkynes to alpha,beta-Unsaturated Aldehydes Using Formic Acid. ORGANIC LETTERS[J]. 2021, 第 11 作者23(6): 2074-2077, https://www.webofscience.com/wos/woscc/full-record/WOS:000631439700022.
[9] Wang, Chengdong, Guo, Yingjie, Wang, Xiaoming, Wang, Zheng, Ding, Kuiling. Ni-Catalyzed Regioselective Hydroarylation of 1-Aryl-1,3-Butadienes with Aryl Halides. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2021, 第 11 作者27(64): 15903-15907, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000702465500001.
[10] Wang, Xiaoming, Han, Zhaobin, Wang, Zheng, Ding, Kuiling. A Type of Structurally Adaptable Aromatic Spiroketal Based Chiral Diphosphine Ligands in Asymmetric Catalysis. ACCOUNTS OF CHEMICAL RESEARCH. 2021, 第 11 作者54(3): 668-684, http://dx.doi.org/10.1021/acs.accounts.0c00697.
[11] Zhang, Linli, Wang, Zheng, Han, Zhaobin, Ding, Kuiling. Manganese-Catalyzed anti-Selective Asymmetric Hydrogenation of alpha-Substituted beta-Ketoamides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2020, 第 4 作者  通讯作者  59(36): 15565-15569, http://dx.doi.org/10.1002/anie.202006383.
[12] Ge, Yao, Wang, Zheng, Han, Zhaobin, Ding, Kuiling. Iridium-Catalyzed Enantioselective Hydrogenation of Indole and Benzofuran Derivatives. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2020, 第 4 作者  通讯作者  26(67): 15482-15486, https://www.webofscience.com/wos/woscc/full-record/WOS:000551435400001.
[13] Ni, Huanzhen, Wong, Yee Lin, Wu, Mingyue, Han, Zhaobin, Ding, Kuiling, Lu, Yixin. Highly Enantioselective 3+2 Annulation of 3-Butynoates with beta-Trifluoromethyl Enones Promoted by an Amine-Phosphine Binary Catalytic System. ORGANIC LETTERS[J]. 2020, 第 5 作者  通讯作者  22(6): 2460-2463, http://dx.doi.org/10.1021/acs.orglett.0c00681.
[14] Zhang, Linli, Wang, Zheng, Han, Zhaobin, Ding, Kuiling. Manganese-Catalyzed anti-Selective Asymmetric Hydrogenation of alpha-Substituted beta-Ketoamides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2020, 第 11 作者59(36): 15565-15569, https://www.webofscience.com/wos/woscc/full-record/WOS:000545489300001.
[15] Ge, Yao, Wang, Zheng, Han, Zhaobin, Ding, Kuiling. Iridium-Catalyzed Enantioselective Hydrogenation of Indole and Benzofuran Derivatives. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2020, 第 11 作者26(67): 15482-15486, https://www.webofscience.com/wos/woscc/full-record/WOS:000551435400001.
[16] Ni, Huanzhen, Wong, Yee Lin, Wu, Mingyue, Han, Zhaobin, Ding, Kuiling, Lu, Yixin. Highly Enantioselective 3+2 Annulation of 3-Butynoates with beta-Trifluoromethyl Enones Promoted by an Amine-Phosphine Binary Catalytic System. ORGANIC LETTERS[J]. 2020, 第 11 作者22(6): 2460-2463, http://dx.doi.org/10.1021/acs.orglett.0c00681.
[17] Zheng, Zhiyao, Cao, Yuxi, Zhu, Dongsheng, Wang, Zheng, Ding, Kuiling. Development of Chiral Spiro Phosphoramidites for Rhodium-Catalyzed Enantioselective Reactions. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2019, 第 5 作者  通讯作者  25(40): 9491-9497, https://www.webofscience.com/wos/woscc/full-record/WOS:000482329000024.
[18] Zheng Zhiyao, Cao Yuxi, Zhu Dongsheng, Wang Zheng, Ding Kuiling. Development of Chiral Spiro Phosphoramidites for Rhodium-Catalyzed Enantioselective Reactions.. CHEMISTRY (WEINHEIM AN DER BERGSTRASSE, GERMANY). 2019, 第 5 作者http://kns.cnki.net/KCMS/detail/detail.aspx?QueryID=0&CurRec=89&recid=&FileName=SJPD64982BD8CE973B8244A255148966D635&DbName=SJPD_06&DbCode=SJPD&yx=&pr=&URLID=&bsm=.
[19] Jia Xiaofei, Ren Xinyi, Wang Zheng, Xia Chungu, Ding Kuiling. Pyrrolyl-Based Phosphoramidite/Rh Catalyzed Asymmetric Hydroformylation of 1,1-Disubstituted Olefins. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 第 5 作者  通讯作者  39(1): 207-214, http://doi.org/10.6023/cjoc201809033.
[20] Guo, Peihua, Zhang, Rui, Wang, Xiaoming, Wang, Zheng, Ding, Kuiling. Synthesis of Chiral Tertiary alpha,alpha-Difluoromethyl Carbinols by Cu-Catalyzed Asymmetric Propargylation. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2019, 第 5 作者  通讯作者  25(71): 16425-16434, http://dx.doi.org/10.1002/chem.201904543.
[21] Gao, Feng, Liang, Yuru, Zhou, Pengfei, Cheng, Jiayi, Ding, Kuiling, Wang, Yang. Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2019, 第 5 作者  通讯作者  178: 177-194, http://dx.doi.org/10.1016/j.ejmech.2019.05.072.
[22] Wu, Mingyue, Han, Zhaobin, Li, Kaizhi, Wu, Jien, Ding, Kuiling, Lu, Yixin. Cyclohexyl-Fused, Spirobiindane-Derived, Phosphine-Catalyzed Synthesis of Tricyclic gamma-Lactams and Kinetic Resolution of gamma-Substituted Allenoates. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 第 5 作者  通讯作者  141(41): 16362-16373,
[23] Zhang, Linli, Tang, Yitian, Han, Zhaobin, Ding, Kuiling. Lutidine-Based Chiral Pincer Manganese Catalysts for Enantioselective Hydrogenation of Ketones. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 第 4 作者  通讯作者  58(15): 4973-4977, http://dx.doi.org/10.1002/anie.201814751.
[24] Jia, Xiaofei, Ren, Xinyi, Wang, Zheng, Xia, Chungu, Ding, Kuiling. Pyrrolyl-Based Phosphoramidite/Rh Catalyzed Asymmetric Hydroformylation of 1,1-Disubstituted Olefins. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 第 5 作者  通讯作者  39(1): 207-214, http://dx.doi.org/10.6023/cjoc201809033.
[25] Ge, Yao, Han, Zhaobin, Wang, Zheng, Ding, Kuiling. Ir-Catalyzed Double Asymmetric Hydrogenation of 3,6-Dialkylidene-2,5-diketopiperazines for Enantioselective Synthesis of Cyclic Dipeptides. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 第 4 作者  通讯作者  141(22): 8981-8988, http://dx.doi.org/10.1021/jacs.9b02920.
[26] Qiu, Jia, Gao, Shen, Li, Chaopeng, Zhang, Lei, Wang, Zheng, Wang, Xiaoming, Ding, Kuiling. Construction of All-Carbon Chiral Quaternary Centers through Cu-I-Catalyzed Enantioselective Reductive Hydroxymethylation of 1,1-Disubstituted Allenes with CO2. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2019, 第 7 作者  通讯作者  25(61): 13874-13878, http://dx.doi.org/10.1002/chem.201903906.
[27] Zheng, Zhiyao, Cao, Yuxi, Zhu, Dongsheng, Wang, Zheng, Ding, Kuiling. Development of Chiral Spiro Phosphoramidites for Rhodium-Catalyzed Enantioselective Reactions. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2019, 第 11 作者25(40): 9491-9497, https://www.webofscience.com/wos/woscc/full-record/WOS:000482329000024.
[28] Zheng Zhiyao, Cao Yuxi, Zhu Dongsheng, Wang Zheng, Ding Kuiling. Development of Chiral Spiro Phosphoramidites for Rhodium-Catalyzed Enantioselective Reactions.. Chemistry (Weinheim an der Bergstrasse, Germany). 2019, 第 4 作者http://kns.cnki.net/KCMS/detail/detail.aspx?QueryID=0&CurRec=89&recid=&FileName=SJPD64982BD8CE973B8244A255148966D635&DbName=SJPD_06&DbCode=SJPD&yx=&pr=&URLID=&bsm=.
[29] Jia Xiaofei, Ren Xinyi, Wang Zheng, Xia Chungu, Ding Kuiling. Pyrrolyl-Based Phosphoramidite/Rh Catalyzed Asymmetric Hydroformylation of 1,1-Disubstituted Olefins. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 第 11 作者39(1): 207-214, http://doi.org/10.6023/cjoc201809033.
[30] Guo, Peihua, Zhang, Rui, Wang, Xiaoming, Wang, Zheng, Ding, Kuiling. Synthesis of Chiral Tertiary alpha,alpha-Difluoromethyl Carbinols by Cu-Catalyzed Asymmetric Propargylation. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2019, 第 11 作者25(71): 16425-16434, https://www.webofscience.com/wos/woscc/full-record/WOS:000497888500001.
[31] Gao, Feng, Liang, Yuru, Zhou, Pengfei, Cheng, Jiayi, Ding, Kuiling, Wang, Yang. Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2019, 第 11 作者178: 177-194, http://dx.doi.org/10.1016/j.ejmech.2019.05.072.
[32] Wu, Mingyue, Han, Zhaobin, Li, Kaizhi, Wu, Jien, Ding, Kuiling, Lu, Yixin. Cyclohexyl-Fused, Spirobiindane-Derived, Phosphine-Catalyzed Synthesis of Tricyclic gamma-Lactams and Kinetic Resolution of gamma-Substituted Allenoates. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 第 11 作者141(41): 16362-16373,
[33] Zhang, Linli, Tang, Yitian, Han, Zhaobin, Ding, Kuiling. Lutidine-Based Chiral Pincer Manganese Catalysts for Enantioselective Hydrogenation of Ketones. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 第 11 作者58(15): 4973-4977,
[34] Ge, Yao, Han, Zhaobin, Wang, Zheng, Ding, Kuiling. Ir-Catalyzed Double Asymmetric Hydrogenation of 3,6-Dialkylidene-2,5-diketopiperazines for Enantioselective Synthesis of Cyclic Dipeptides. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 第 11 作者141(22): 8981-8988, https://www.webofscience.com/wos/woscc/full-record/WOS:000470939200046.
[35] Jia, Xiaofei, Ren, Xinyi, Wang, Zheng, Xia, Chungu, Ding, Kuiling. Pyrrolyl-Based Phosphoramidite/Rh Catalyzed Asymmetric Hydroformylation of 1,1-Disubstituted Olefins. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 第 11 作者39(1): 207-214, http://dx.doi.org/10.6023/cjoc201809033.
[36] Qiu, Jia, Gao, Shen, Li, Chaopeng, Zhang, Lei, Wang, Zheng, Wang, Xiaoming, Ding, Kuiling. Construction of All-Carbon Chiral Quaternary Centers through Cu-I-Catalyzed Enantioselective Reductive Hydroxymethylation of 1,1-Disubstituted Allenes with CO2. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2019, 第 11 作者25(61): 13874-13878, https://www.webofscience.com/wos/woscc/full-record/WOS:000490313800001.
[37] 胡金波, 丁奎岭. 有机氟化学：独特和有用的化学研究前沿. 化学学报[J]. 2018, 第 2 作者76(12): 905-906, http://lib.cqvip.com/Qikan/Article/Detail?id=6100115484.
[38] Wang, Xiaoming, Ding, Kuiling. Making Spiroketal-based Diphosphine (SKP) Ligands via a Catalytic Asymmetric Approach. CHINESE JOURNAL OF CHEMISTRY[J]. 2018, 第 2 作者  通讯作者  36(10): 899-903, http://lib.cqvip.com/Qikan/Article/Detail?id=676614910.
[39] Ge, Yao, Han, Zhaobin, Wang, Zheng, Feng, ChenGuo, Zhao, Qian, Lin, GuoQiang, Ding, Kuiling. Ir-SpinPHOX Catalyzed Enantioselective Hydrogenation of 3-Ylidenephthalides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 第 7 作者  通讯作者  57(40): 13140-13144, https://www.webofscience.com/wos/woscc/full-record/WOS:000445445700023.
[40] Pengfei Zhou, Yuru Liang, Hao Zhang, Hao Jiang, Kechang Feng, Pan Xu, Jie Wang, Xiaoming Wang, Kuiling Ding, Cheng Luo, Mingming Liu, Yang Wang. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2018, 第 9 作者144: 817-842, http://dx.doi.org/10.1016/j.ejmech.2017.12.004.
[41] Hu Jinbo, Ding Kuiling. Organofluorine Chemistry: A Unique and Useful Research Frontier of Chemistry. ACTA CHIMICA SINICA. 2018, 第 2 作者76(12): 905-906, https://www.webofscience.com/wos/woscc/full-record/WOS:000456161700001.
[42] Wang, Haixia, Yu, Lulu, Xie, Mingsheng, Wu, Jiang, Qu, Guirong, Ding, Kuiling, Guo, Haiming. Regio- and Enantioselective Allylic Amination of Aliphatic MBH Adducts with N-Heteroaromatics. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2018, 第 6 作者  通讯作者  24(6): 1425-1430, https://www.webofscience.com/wos/woscc/full-record/WOS:000423351800027.
[43] 丁奎岭. 合成创造未来. 世界科学[J]. 2018, 第 1 作者20-22, http://lib.cqvip.com/Qikan/Article/Detail?id=676046638.
[44] Zhou, Pengfei, Liang, Yuru, Zhang, Hao, Jiang, Hao, Feng, Kechang, Xu, Pan, Wang, Jie, Wang, Xiaoming, Ding, Kuiling, Luo, Cheng, Liu, Mingming, Wang, Yang. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2018, 第 9 作者  通讯作者  144: 817-842, https://www.webofscience.com/wos/woscc/full-record/WOS:000425198100062.
[45] Zheng, Zhiyao, Cao, Yuxi, Chong, Qinglei, Han, Zhaobin, Ding, Jiaming, Luo, Chenguang, Wang, Zheng, Zhu, Dongsheng, Zhou, QiLin, Ding, Kuiling. Chiral Cyclohexyl-Fused Spirobiindanes: Practical Synthesis, Ligand Development, and Asymmetric Catalysis. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2018, 第 10 作者  通讯作者  140(32): 10374-10381, http://dx.doi.org/10.1021/jacs.8b07125.
[46] 胡金波, 丁奎岭. ��. 化学学报[J]. 2018, 第 2 作者76(12): 905-906, http://lib.cqvip.com/Qikan/Article/Detail?id=6100115484.
[47] Wang, Xiaoming, Ding, Kuiling. Making Spiroketal-based Diphosphine (SKP) Ligands via a Catalytic Asymmetric Approach. CHINESE JOURNAL OF CHEMISTRY[J]. 2018, 第 11 作者36(10): 899-903, http://lib.cqvip.com/Qikan/Article/Detail?id=676614910.
[48] Ge, Yao, Han, Zhaobin, Wang, Zheng, Feng, ChenGuo, Zhao, Qian, Lin, GuoQiang, Ding, Kuiling. Ir-SpinPHOX Catalyzed Enantioselective Hydrogenation of 3-Ylidenephthalides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 第 11 作者57(40): 13140-13144, https://www.webofscience.com/wos/woscc/full-record/WOS:000445445700023.
[49] Pengfei Zhou, Yuru Liang, Hao Zhang, Hao Jiang, Kechang Feng, Pan Xu, Jie Wang, Xiaoming Wang, Kuiling Ding, Cheng Luo, Mingming Liu, Yang Wang. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral ��-lactam bridged combretastatin A-4 analogues as potent antitumor agents. European Journal of Medicinal Chemistry. 2018, 第 9 作者144: 817-842, http://dx.doi.org/10.1016/j.ejmech.2017.12.004.
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[51] Wang, Haixia, Yu, Lulu, Xie, Mingsheng, Wu, Jiang, Qu, Guirong, Ding, Kuiling, Guo, Haiming. Regio- and Enantioselective Allylic Amination of Aliphatic MBH Adducts with N-Heteroaromatics. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2018, 第 11 作者24(6): 1425-1430, https://www.webofscience.com/wos/woscc/full-record/WOS:000423351800027.
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[326] 王以, 李欣, 丁奎岭. The synthesis of a new generation of MAP ligands containing two types of chiral elements for asymmetic catalysis. TETRAHEDRON LETT.[J]. 2002, 第 3 作者43(1): 159-161, http://ir.sioc.ac.cn/handle/331003/17739.
[327] 杜海峰, 龙江, 胡婕妤, 李欣, 丁奎岭. 3.3'-Br^2-BINOL-Zn complex: A highly efficient catalyst for the enzntioselective Hetero-Diels-Alder reaction. ORG. LETT.[J]. 2002, 第 5 作者4(24): 4349-4352, http://ir.sioc.ac.cn/handle/331003/17737.
[328] 袁宇, 李欣, 孙杰, 丁奎岭. To probe the origin of activation effect of carboxylic acid and (+)-NLE in tridentated titanium ctalyst systems. J. AM. CHEM. SOC.[J]. 2002, 第 4 作者124(50): 14866-14867, http://ir.sioc.ac.cn/handle/331003/17751.
[329] 龙江, 丁奎岭. Engineering catalysts for enantioselective addition of diethylzinc to aldehydes with racemic amino alcohols: Nonlinear effects in asymmetric deactivation of racemic catalysts.. Angew. Chem.-Int. Edit.[J]. 2001, 第 2 作者40(3): 544-547, http://ir.sioc.ac.cn/handle/331003/17727.
[330] 王以, 丁奎岭. ��Friedel-Crafts ��. 有机化学[J]. 2001, 第 2 作者21(1): 653-767, http://ir.sioc.ac.cn/handle/331003/17731.
[331] Koichi Mikami, Remy angelaud, 丁奎岭, Akihiro Ishii, Akito Tanaka, Naotaka Sawada, Kenichi Kudo, Masaaki Senda. Asymmetric activation of chiral alkoxyzinc catalysts by chiral nitrogen activators for dialkylzinc addition to aldehydes: Super High-Throughput screening of combinatorial libraries of chiral ligands and activators by by HPLC-CD/UV and HPLC-OR/RIU systems. Chem.-Eur. J.[J]. 2001, 第 3 作者7(3): 730-737, http://ir.sioc.ac.cn/handle/331003/17729.
[332] 王以, 丁奎岭. Highly regio-and enantioselective palladium-catalyzed allylic amination with sodium diformylamide. J. Org. Chem.[J]. 2001, 第 2 作者66(9): 3238-3241, http://ir.sioc.ac.cn/handle/331003/17721.
[333] 张如洲, 余立兵, 徐立, 王致勤, 丁奎岭. Pd-catalyzed asymmetric allylation with a novel C^2-symmetric bisphosphinite ligand: 3R,3'-bis(diphenylphosphinoxy)-6,6,6'6'-tetramethyl-2S,2'S-di-4H-pyran. Tetrahedron Lett.[J]. 2001, 第 5 作者42(43): 7659-7662, http://ir.sioc.ac.cn/handle/331003/17723.
[334] 郭辉, 王以, 丁奎岭. Synthesis of some novel amino phenols with ocatahydro-1,1'-bi-nahthyl backbone. Chin. J. Chem.[J]. 2001, 第 3 作者19(1): 52-57, http://ir.sioc.ac.cn/handle/331003/17725.
[335] 龙江, 丁奎岭. Engineering catalysts for enantioselective addition of diethylzinc to aldehydes with racemic amino alcohols: Nonlinear effects in asymmetric deactivation of racemic catalysts.. ANGEW. CHEM.-INT. EDIT.[J]. 2001, 第 2 作者40(3): 544-547, http://ir.sioc.ac.cn/handle/331003/17727.
[336] 王以, 丁奎岭. 催化不对称Friedel-Crafts 反应. 有机化学[J]. 2001, 第 2 作者21(1): 653-767, http://ir.sioc.ac.cn/handle/331003/17731.
[337] Koichi Mikami, Remy angelaud, 丁奎岭, Akihiro Ishii, Akito Tanaka, Naotaka Sawada, Kenichi Kudo, Masaaki Senda. Asymmetric activation of chiral alkoxyzinc catalysts by chiral nitrogen activators for dialkylzinc addition to aldehydes: Super High-Throughput screening of combinatorial libraries of chiral ligands and activators by by HPLC-CD/UV and HPLC-OR/RIU systems. CHEM.-EUR. J.[J]. 2001, 第 3 作者7(3): 730-737, http://ir.sioc.ac.cn/handle/331003/17729.
[338] 王以, 丁奎岭. Highly regio-and enantioselective palladium-catalyzed allylic amination with sodium diformylamide. J. ORG. CHEM.[J]. 2001, 第 2 作者66(9): 3238-3241, http://ir.sioc.ac.cn/handle/331003/17721.
[339] 张如洲, 余立兵, 徐立, 王致勤, 丁奎岭. Pd-catalyzed asymmetric allylation with a novel C^2-symmetric bisphosphinite ligand: 3R,3'-bis(diphenylphosphinoxy)-6,6,6'6'-tetramethyl-2S,2'S-di-4H-pyran. TETRAHEDRON LETT.[J]. 2001, 第 5 作者42(43): 7659-7662, http://ir.sioc.ac.cn/handle/331003/17723.
[340] 郭辉, 王以, 丁奎岭. Synthesis of some novel amino phenols with ocatahydro-1,1'-bi-nahthyl backbone. CHIN. J. CHEM.[J]. 2001, 第 3 作者19(1): 52-57, http://ir.sioc.ac.cn/handle/331003/17725.
[341] 丁奎岭, 林国强. ��. 有机化学[J]. 2000, 第 1 作者20(1): 1-10, http://ir.sioc.ac.cn/handle/331003/16547.
[342] 丁奎岭. ��. 有机化学. 2000, 第 1 作者20(5): 613-622, http://lib.cqvip.com/Qikan/Article/Detail?id=4666563.
[343] 郭辉, 丁奎岭. Reduction of 1,1'-binaphthyls to octahydro-1,1'-binathyl derivatives with Raneg Ni-Al alloy in aqueous solution. Tetrahedron Lett.[J]. 2000, 第 2 作者41(51): 10061-10064, http://ir.sioc.ac.cn/handle/331003/17713.
[344] 丁奎岭, 林国强. 催化不对称反应不对称活化的最新进展. 有机化学[J]. 2000, 第 1 作者20(1): 1-10, http://ir.sioc.ac.cn/handle/331003/16547.
[345] 丁奎岭. 催化不对称反应最新进展（Ⅱ）－组合化学方法之应用. 有机化学[J]. 2000, 第 1 作者20(5): 613-622, https://sioc-journal.cn/Jwk_yjhx/CN/Y2000/V20/I5/613.
[346] 郭辉, 丁奎岭. Reduction of 1,1'-binaphthyls to octahydro-1,1'-binathyl derivatives with Raneg Ni-Al alloy in aqueous solution. TETRAHEDRON LETT.[J]. 2000, 第 2 作者41(51): 10061-10064, http://ir.sioc.ac.cn/handle/331003/17713.
[347] 丁奎岭, 郭辉. Raney Ni-Al对芳环的还原反应：光学活性H 8 -BINOL的简便合成. 厦门大学学报：自然科学版[J]. 1999, 第 1 作者181-181, http://lib.cqvip.com/Qikan/Article/Detail?id=4000766605.
[348] 丁奎岭, 郭辉. Raney Ni-Al��H 8 -BINOL��. 厦门大学学报：自然科学版. 1999, 第 1 作者181-181, http://lib.cqvip.com/Qikan/Article/Detail?id=4000766605.

发表著作

（ 1 ）不对称催化中的新概念与新方法, Asymmetric Catalysis：New Concepts and Methods, 化学工业出版社, 2008-05, 第 1 作者
（ 2 ）不对称非均相催化手册, Handbook of Asymmetric Heterogeneous Catalysis, Wiley-VCH, 2008-06, 第 1 作者
（ 3 ）有机化学-突破和展望, Organic Chemistry-Breakthroughs and Perspectives, Wiley-VCH , 2012-08, 第 1 作者

科研活动

科研项目

（ 1 ）手性催化的重要科学基础, 主持, 国家级, 2010-01--2014-12
（ 2 ）抗癌药紫杉醇的合成研究, 主持, 省级, 2011-01--2013-12
（ 3 ）一类新螺环骨架手性配体的设计合成与应用, 主持, 国家级, 2012-01--2015-12
（ 4 ）金属有机催化材料的可控制自组装与性能研究, 主持, 国家级, 2012-01--2015-12
（ 5 ）食品、饲料中禁限用添加剂检测用同位素标记标准品的研制(上海市计量测试技术研究院), 主持, 省级, 2012-09--2014-09
（ 6 ）手性环氧氯丙烷药物关键中间体新一代制造工艺与工业生产(中科院长春分院), 主持, 省级, 2012-01--2013-12
（ 7 ）两性离子镍络合物催化的一氧化碳和二氧化碳的转化, 主持, 国家级, 2013-01--2014-12
（ 8 ）特色手性骨架配体与催化剂研究, 主持, 国家级, 2013-01--2017-12
（ 9 ）挑战性羰基化合物的选择性催化氢化, 主持, 国家级, 2015-01--2018-12
（ 10 ）绿色高效螺环配体催化合成依折麦布, 主持, 国家级, 2014-01--2016-12
（ 11 ）烃类物质绿色催化转化的基础研究, 主持, 国家级, 2013-09--2016-08

参与会议

（1）Cooperative Catalysis in Asymmetric Synthesis and CO2 Transformation   2016-10-23
（2）Chiral Ligand Design: from Spiro to Spiro   2016-09-29
（3）Chiral Ligand Design: from Spiro to Spiro   2016-09-29
（4）Cooperative Catalysis in Asymmetric Synthesis and CO2 Transformation   2016-07-03
（5）Chiral Catalyst Evolution Rational Design and Serendipity   Kuiling Ding   2015-01-30
（6）Cooperative Catalysis in Asymmetric Synthesis and CO2 Transformation Case Study of Catalyst Design and Process Innovation   Kuiling Ding   2014-12-15
（7）Chiral Catalyst Evolution: Rational Design and Serendipity   中国化学会第十七届全国金属有机化学学术讨论会   丁奎岭   2012-10-20
（8）Cooperative catalysis in enantioselective cyanation of aldehydes   Ding Kuiling   2010-12-15
（9）Highly Efficient Chiral Organometallic Catalysts for Homo- and Heterogeneous Asymmetric Hydrogenation   Ding Kuiling   2010-12-15
（10）Development of Highly Efficient Chiral Catalysts for Homo and Heterogeneous Asymmetric Reactions   Ding Kuiling   2010-12-11
（11）Endeavors towards Bridging the Gap between Homo and Heterogeneous Asymmetric Catalysis with Organometallics   第十五届全国催化学术会议   Ding Kuiling   2010-11-29
（12）Highly Efficient Chiral Organometallic Catalysts for Homo- and Heterogeneous Asymmetric Hydrogenation   Ding Kuiling   2010-06-15
（13）Highly Efficient Chiral Organometallic Catalysts for Homo- and Heterogeneous Asymmetric Hydrogenation   Ding Kuiling   2010-04-26

指导学生

已指导学生

肖友利博士研究生 070303-有机化学

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赵宝国博士研究生 070303-有机化学

王细胜博士研究生 070303-有机化学

杜海峰博士研究生 070303-有机化学

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