基本信息
高福 男 博导 微生物研究所
电子邮件:gaof@im.ac.cn
通信地址:北京市朝阳区北辰西路1号院3号
邮政编码:1000101

研究领域

病原微生物与免疫学, 主要研究病原微生物与宿主互作及宿主免疫识别过程中相关的蛋白质结构与功能。
分子免疫学领域:集中研究T细胞免疫中分子识别的蛋白质与蛋白质的相互作用,尤其是细胞界面的表面蛋白质(受体与配体)之间的相互作用。
分子病毒学领域:囊膜病毒侵入的分子机制,尤其是细胞受体与病毒囊膜蛋白相互作用及融合抑制剂的药物设计。
分子流行病学与分子进化:近几年来,联合国内其他优势单位,对野生水禽感染禽流感、人感染2型猪链球菌、猪的无名高热等传染病进行了系统研究。

招生信息

   
招生专业
071010-生物化学与分子生物学
071007-遗传学
招生方向
免疫识别的结构基础与病原微生物跨种间传播的分子机制

教育背景

1991-09--1994-08 英国牛津大学 博士
1983-09--1986-07 北京农业大学(现中国农业大学) 硕士
1979-09--1983-07 山西农业大学 学士
学历
1991 - 1995, 英国牛津大学 (Oxford University),博士,生物化学。
1983 - 1986, 北京农业大学,硕士,微生物学与动物传染病学。
1979 - 1983, 山西农业大学,学士,兽医学。
学位
-- 博士
出国学习工作

1991-1994 年 英国牛津大学 博士 ( DPhil-Oxon )(师从 David H L Bishop, Ernest A Gould )
1994 年(3个月) 加拿大 Calgary University 博士后(师从 Robert Bell )  1995-1998 年 英国牛津大学 博士后(师从 John I bell, Andrew J McMichael, Bent K Jakobsen )
1999-2001 年 美国哈佛大学 / 哈佛医学院 博士后(师从 Don C Wiley, Stephen C Harrison )(工作期间资助:英国 Wellcome Trust International Travelling Fellow )
2001-2004 年 英国牛津大学 讲师、博士生导师、 Group leader

工作经历

1986-1991 年 北京农业大学 助教 / 讲师
1994 年(3个月) 加拿大 Calgary University 博士后(师从 Robert Bell )   
1995-1998 年 英国牛津大学 博士后(师从 John I bell, Andrew J McMichael, Bent K Jakobsen )
1999-2001 年 美国哈佛大学 / 哈佛医学院 博士后(师从 Don C Wiley, Stephen C Harrison )(工作期间资助:英国 Wellcome Trust International Travelling Fellow )
2001-2004 年 英国牛津大学 讲师、博士生导师、 Group leader
2004 -2008年 中国科学院微生物研究所 所长
2004-至今   中国科学院微生物研究所 研究员、博士生导师
2008-至今   中国科学院北京生命科学研究院 副院长,中国科学院病原微生物与免疫学重点实验室 主任  
2010-至今   英国牛津大学 客座教授
2011-至今   中国疾病预防控制中心 副主任
社会兼职
2012-01--今 《Philosophical Transactions of the Royal Society B: Biological Sciences》杂志
2011-10--今 中国微生物学会病毒学专业委员会 ,副主任委员
2011-06--今 中国科学技术协会,第八届常委
2010-12--今 中国生物工程学会,第五届理事会副理事长
2010-10--今 中国免疫学会
2010-01--今 《Protein & Cell》杂志
2010-01--今 牛津大学,客座教授
2009-01--今 《Experimental Biology and Medicine》杂志
2006-06--今 国际抗病毒联盟(ICAV)

出版信息

   
发表论文
[1] Lili Wu, Anqi Zheng, Yangming Tang, Xiaoyun Wang, Yue Gao, Wenwen Lei, Guizhen Wu, Qihui Wang, George Fu Gao. Efficient inhibition of SARS-CoV-2 emerging EG.5, EG.5.1 and BA.2.86 variants by fusion inhibitor HY3000 peptide. HLIFE. 2024, 2(1): 43-46, http://dx.doi.org/10.1016/j.hlife.2023.10.002.
[2] 高福. 迈入开放科学新时代. 科学通报. 2023, 68(1): 1-2, https://kns.cnki.net/kcms2/article/abstract?v=M9N_p6ifsvPtWu3RoqxSZgqdJkWN9bz1vwZGEJjFDSV5KrbkHE2QFRDj-Tm-_vUqlhJPIb1P52_azuIvR3jz_9ls2IAasob4R9gxHfQHTQL7oyomqRgMSlsBVgaGLsBR&uniplatform=NZKPT&language=gb.
[3] 高福. 主编寄语:开放科学助力全球可持续发展. 科学通报:英文版. 2023, 68(1): 1-1, http://lib.cqvip.com/Qikan/Article/Detail?id=7109109502.
[4] Xiaoyun Wang, Yufeng Xie, Honghui Liu, Wenwen Lei, Ke Xu, Lili Wu, Ruiwen Fan, Guizhen Wu, George Fu Gao, Qihui Wang. A broadly neutralizing nanobody targeting the highly conserved S2 subunit of sarbecoviruses. SCIENCE BULLETIN[J]. 2023, 68(7): 684-687, http://dx.doi.org/10.1016/j.scib.2023.03.027.
[5] Lu, Dan, Chen, Yuan, Jiang, Min, Wang, Jie, Li, Yiting, Ma, Keke, Sun, Wenqiao, Zheng, Xing, Qi, Jianxun, Jin, Wenjing, Chen, Yu, Chai, Yan, Zhang, Catherine W H, Liang, Hao, Tan, Shuguang, Gao, George F. KRAS G12V neoantigen specific T cell receptor for adoptive T cell therapy against tumors. NATURE COMMUNICATIONS[J]. 2023, 14(1): http://dx.doi.org/10.1038/s41467-023-42010-1.
[6] Gainza, Pablo, Wehrle, Sarah, Van HallBeauvais, Alexandra, Marchand, Anthony, Scheck, Andreas, Harteveld, Zander, Buckley, Stephen, Ni, Dongchun, Tan, Shuguang, Sverrisson, Freyr, Goverde, Casper, Turelli, Priscilla, Raclot, Charlene, Teslenko, Alexandra, Pacesa, Martin, Rosset, Stephane, Georgeon, Sandrine, Marsden, Jane, Petruzzella, Aaron, Liu, Kefang, Xu, Zepeng, Chai, Yan, Han, Pu, Gao, George F, Oricchio, Elisa, Fierz, Beat, Trono, Didier, Stahlberg, Henning, Bronstein, Michael, Correia, Bruno E. De novo design of protein interactions with learned surface fingerprints. NATURE. 2023, 617(7959): 176-184, http://dx.doi.org/10.1038/s41586-023-05993-x.
[7] Han, Lingxia, Wu, Shaolian, Zhang, Ting, Peng, Weiyu, Zhao, Min, Yue, Can, Wen, Wanxin, Cai, Wenbo, Li, Min, Wallny, HansJoachim, Avila, David W, Mwangi, William, Nair, Venugopa, Ternette, Nicola, Guo, Yaxin, Zhao, Yingze, Chai, Yan, Qi, Jianxun, Liang, Hao, Gao, George F, Kaufman, Jim, Liull, William J. A Wider and Deeper Peptide-Binding Groove for the Class I Molecules from B15 Compared with B19 Chickens Correlates with Relative Resistance to Marek's Disease. JOURNAL OF IMMUNOLOGY[J]. 2023, 210(5): 668-680, http://dx.doi.org/10.4049/jimmunol.2200211.
[8] Zhao, Zhennan, Huang, Youhua, Liu, Congcong, Zhu, Dongjie, Gao, Shuaixin, Liu, Sheng, Peng, Ruchao, Zhang, Ya, Huang, Xiaohong, Qi, Jianxun, Wong, Catherine C L, Zhang, Xinzheng, Wang, Peiyi, Qin, Qiwei, Gao, George F. Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly. NATURE COMMUNICATIONS[J]. 2023, 14(1): http://dx.doi.org/10.1038/s41467-023-37681-9.
[9] Li, Dedong, Duan, Minrun, Wang, Xiao, Gao, Pengyue, Zhao, Xin, Xu, Kun, Gao, George F F. Neutralization of BQ.1, BQ.1.1, and XBB with RBD-Dimer Vaccines. NEW ENGLAND JOURNAL OF MEDICINE. 2023, http://dx.doi.org/10.1056/NEJMc2216233.
[10] Guo, Shuxin, Zheng, Yuxuan, Gao, Zhengrong, Duan, Minrun, Liu, Sheng, Du, Pan, Xu, XiaoYu, Xu, Kun, Zhao, Xin, Chai, Yan, Wang, Peiyi, Zhao, Qi, Gao, George F, Dai, Lianpan. Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine. CELL DISCOVERY[J]. 2023, 9(1): http://dx.doi.org/10.1038/s41421-023-00585-5.
[11] Wang, Yanan, Xu, Xuebin, Zhu, Baoli, Lyu, Na, Liu, Yue, Ma, Sufang, Jia, Shulei, Wan, Bo, Du, Yongkun, Zhang, Gaiping, Gao, George F. Genomic analysis of almost 8,000 Salmonella genomes reveals drivers and landscape of antimicrobial resistance in China. MICROBIOLOGY SPECTRUM[J]. 2023, http://dx.doi.org/10.1128/spectrum.02080-23.
[12] An, Yaling, Zhao, Gan, Duan, Huixin, Zhang, Ning, Duan, Minrun, Xu, Senyu, Liu, Xueyuan, Han, Yuxuan, Zheng, Tianyi, Li, Xin, Hou, Jiawang, Zhang, Zhiyu, Bi, Yuhai, Zhao, Xin, Xu, Kun, Dai, Lianpan, Wang, Bin, Gao, George F. Robust and protective immune responses induced by heterologous prime-boost vaccination with DNA-protein dimeric RBD vaccines for COVID-19. JOURNAL OF MEDICAL VIROLOGY[J]. 2023, 95(7): http://dx.doi.org/10.1002/jmv.28948.
[13] Liu, Maoshun, Zhang, Jie, Li, Lei, Tian, Jinmin, Yang, Mengjie, Shang, Bingli, Wang, Xin, Li, Min, Li, Hongmei, Yue, Can, Yao, Sijia, Lin, Ying, Guo, Yuanyuan, Zong, Kexin, Zhang, Danni, Zhao, Yingze, Cai, Kun, Dong, Shaobo, Xu, Shengping, Zhan, Jianbo, Gao, George F, Liu, William J. Inactivated vaccine fueled adaptive immune responses to Omicron in 2-year COVID-19 convalescents. JOURNAL OF MEDICAL VIROLOGY[J]. 2023, 95(8): http://dx.doi.org/10.1002/jmv.28998.
[14] Gao, George F F. Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19. NATURE IMMUNOLOGY. 2023, 24(7): 1056-1057, http://dx.doi.org/10.1038/s41590-023-01539-5.
[15] Li, Yulei, Liu, Peipei, Hao, Tianjiao, Liu, Sheng, Wang, Xi, Xie, Yufeng, Xu, Ke, Lei, Wenwen, Zhang, Cheng, Han, Pu, Li, Ying, Jin, Xiyue, Huan, Yu, Lu, Yafei, Zhang, Rong, Li, Xiaoyan, Zhao, Xin, Xu, Kun, Liao, Pu, Lu, Xuancheng, Bi, Yuhai, Song, Hao, Wu, Guizhen, Zhu, Baoli, Gao, George F. Rational design of an influenza-COVID-19 chimeric protective vaccine with HA-stalk and S-RBD. EMERGING MICROBES & INFECTIONS[J]. 2023, 12(2): http://dx.doi.org/10.1080/22221751.2023.2231573.
[16] Hu, Yu, Liu, Kefang, Han, Pu, Xu, Zepeng, Zheng, Anqi, Pan, Xiaoqian, Jia, Yunfei, Su, Chao, Tang, Lingfeng, Wu, Lili, Bai, Bin, Zhao, Xin, Tian, Di, Chen, Zhihai, Qi, Jianxun, Wang, Qihui, Gao, George F. Host range and structural analysis of bat-origin RshSTT182/200 coronavirus binding to human ACE2 and its animal orthologs. EMBO JOURNAL[J]. 2023, 42(4): http://dx.doi.org/10.15252/embj.2022111737.
[17] 王晓云, 谢宇峰, 刘红辉, 雷雯雯, 徐柯, 仵丽丽, 范瑞文, 武桂珍, 高福, 王奇慧. 一株靶向沙贝病毒高度保守的S2亚基的广谱中和纳米抗体. 科学通报:英文版. 2023, 68(7): 684-687, http://lib.cqvip.com/Qikan/Article/Detail?id=7109530108.
[18] 王奇慧, 齐建勋, 严景华, 高福. 平急一体化传染病防控平台在新冠肺炎疫情中的应用. 中国科学基金[J]. 2022, 36(4): 603-609, http://lib.cqvip.com/Qikan/Article/Detail?id=7108136608.
[19] Dai, Lianpan, Gao, Lidong, Tao, Lifeng, Hadinegoro, Sri R, Erkin, Musabaev, Ying, Zhifang, He, Peng, Girsang, Rodman T, Vergara, Hugo, Akram, Javed, Satari, Hindra, I, Khaliq, Tanwir, Sughra, Ume, Celi, Ana P, Li, Fangjun, Li, Yan, Jiang, Zhiwei, Dalimova, Dilbar, Tuychiev, Jaloliddin, Turdikulova, Shahlo, Ikram, Aamer, Flores Lastra, Nancy, Ding, Fan, Suhardono, Mahendra, Fadlyana, Eddy, Yan, Jinghua, Hu, Zhongyu, Li, Changgui, Abdurakhmonov, Ibrokhim Y, Gao, George F, ZF2001 Global Trial Grp. Efficacy and Safety of the RBD-Dimer-Based Covid-19 Vaccine ZF2001 in Adults. NEW ENGLAND JOURNAL OF MEDICINE. 2022, http://dx.doi.org/10.1056/NEJMoa2202261.
[20] Zheng, Anqi, Wu, Lili, Ma, Renyi, Han, Pu, Huang, Baoying, Qiao, Chengpeng, Wang, Qihui, Tan, Wenjie, Gao, George F, Han, Pengcheng. A binding-enhanced but enzymatic activity-eliminated human ACE2 efficiently neutralizes SARS-CoV-2 variants. SIGNAL TRANSDUCTION AND TARGETED THERAPY[J]. 2022, 7(1): 362-365, http://dx.doi.org/10.1038/s41392-021-00821-y.
[21] Fan, Wenhui, Sun, Shanshan, Zhang, Ning, Zhang, Yuan, Jiao, Pengtao, Wang, Jian, Gao, George F, Liu, Wenjun, Bi, Yuhai, Yang, Limin. Nasal delivery of thermostable and broadly neutralizing antibodies protects mice against SARS-CoV-2 infection. SIGNAL TRANSDUCTION AND TARGETED THERAPYnull. 2022, 7(1): 628-631, http://dx.doi.org/10.1038/s41392-022-00911-5.
[22] An, Yaling, Li, Shihua, Jin, Xiyue, Han, JianBao, Xu, Kun, Xu, Senyu, Han, Yuxuan, Liu, Chuanyu, Zheng, Tianyi, Liu, Mei, Yang, Mi, Song, TianZhang, Huang, Baoying, Zhao, Li, Wang, Wen, A, Ruhan, Cheng, Yingjie, Wu, Changwei, Huang, Enqi, Yang, Shilong, Wong, Gary, Bi, Yuhai, Ke, Changwen, Tan, Wenjie, Yan, Jinghua, Zheng, YongTang, Dai, Lianpan, Gao, George F. A tandem-repeat dimeric RBD protein-based covid-19 vaccine zf2001 protects mice and nonhuman primates. EMERGING MICROBES & INFECTIONS[J]. 2022, 11(1): 1058-1071, http://dx.doi.org/10.1080/22221751.2022.2056524.
[23] Feng, Yuqing, Wang, Yanan, Zhu, Baoli, Gao, George Fu, Guo, Yuming, Hu, Yongfei. Metagenome-assembled genomes and gene catalog from the chicken gut microbiome aid in deciphering antibiotic resistomes. COMMUNICATIONS BIOLOGYnull. 2022, 5(1): [24] Li, Hui, Zhao, Min, Zhang, Hangjie, Quan, Chuansong, Zhang, Dannie, Liu, Yingmei, Liu, Meng, Xue, Chunxue, Tan, Shuguang, Guo, Yaxin, Zhao, Yingze, Wu, Guizhen, Gao, George F, Cao, Bin, Liu, William J. Pneumonia Severity and Phase Linked to Virus-Specific T Cell Responses with Distinct Immune Checkpoints during pH1N1 Infection. JOURNAL OF IMMUNOLOGY[J]. 2022, 208(9): 2154-2162, http://dx.doi.org/10.4049/jimmunol.2101021.
[25] Zhao, Xin, Li, Dedong, Ruan, Wenjing, Chen, Zhihai, Zhang, Rong, Zheng, Anqi, Qiao, Shitong, Zheng, Xinlei, Zhao, Yingze, Dai, Lianpan, Han, Pengcheng, Gao, George F. Effects of a Prolonged Booster Interval on Neutralization of Omicron Variant. NEW ENGLAND JOURNAL OF MEDICINEnull. 2022, 386(9): 894-896, http://dx.doi.org/10.1056/NEJMc2119426.
[26] Li, Zhaohui, Li, Shihua, Zhang, Gen, Peng, Weiyu, Chang, Zhen, Zhang, Xue, Fan, Zheng, Chai, Yan, Wang, Feiran, Zhao, Xin, Li, Dedong, Zhang, Rong, He, Zhanlong, Zou, Weiwei, Xu, Ke, Lei, Wenwen, Liu, Peipei, Hao, Junfeng, Zhang, Jingjing, Sun, Litao, Wu, Guizhen, Tan, Shuguang, Gao, George Fu, Gao, Feng, Wu, Yan. An engineered bispecific human monoclonal antibody against SARS-CoV-2. NATURE IMMUNOLOGY[J]. 2022, 23(3): 423-+, http://dx.doi.org/10.1038/s41590-022-01138-w.
[27] Dai, Lianpan, Gao, Lidong, Tao, Lifeng, Hadinegoro, Sri R, Erkin, Musabaev, Ying, Zhifang, He, Peng, Girsang, Rodman T, Vergara, Hugo, Akram, Javed, Satari, Hindra, I, Khaliq, Tanwir, Sughra, Ume, Celi, Ana P, Li, Fangjun, Li, Yan, Jiang, Zhiwei, Dalimova, Dilbar, Tuychiev, Jaloliddin, Turdikulova, Shahlo, Ikram, Aamer, Flores Lastra, Nancy, Ding, Fan, Suhardono, Mahendra, Fadlyana, Eddy, Yan, Jinghua, Hu, Zhongyu, Li, Changgui, Abdurakhmonov, Ibrokhim Y, Gao, George F, ZF2001 Global Trial Grp. Efficacy and Safety of the RBD-Dimer-Based Covid-19 Vaccine ZF2001 in Adults. NEW ENGLAND JOURNAL OF MEDICINE[J]. 2022, 386(22): 2097-2111, http://dx.doi.org/10.1056/NEJMoa2202261.
[28] Linjie Li, Hanyi Liao, Yumin Meng, Weiwei Li, Pengcheng Han, Kefang Liu, Qing Wang, Dedong Li, Yanfang Zhang, Liang Wang, Zheng Fan, Yuqin Zhang, Qiyue Wang, Xin Zhao, Yeping Sun, Niu Huang, Jianxun Qi, George Fu Gao. Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1. CELL. 2022, 185(16): 2952-2960.e10, http://dx.doi.org/10.1016/j.cell.2022.06.023.
[29] Laybohr Kamara, Idrissa, Wang, Liang, Guo, Yaxin, Huo, Shuting, Guo, Yuanyuan, Xu, Chengdong, Liao, Yilan, Liu, William J, Ma, Wei, Gao, George F. Spatial-temporal heterogeneity and determinants of HIV prevalence in the Mano River Union countries. INFECTIOUS DISEASES OF POVERTY[J]. 2022, 11(1): 96-96, http://lib.cqvip.com/Qikan/Article/Detail?id=7109295325.
[30] Han, Yuxuan, An, Yaling, Chen, Qian, Xu, Kun, Liu, Xueyuan, Xu, Senyu, Duan, Huixin, Vogel, Annette B, Sahin, Ugur, Wang, Qihui, Dai, Lianpan, Gao, George F. mRNA vaccines expressing homo-prototype/Omicron and hetero-chimeric RBD-dimers against SARS-CoV-2. CELL RESEARCHnull. 2022, 32(11): 1022-1025, http://lib.cqvip.com/Qikan/Article/Detail?id=7108912232.
[31] Jin, Pengfei, Guo, Xiling, Chen, Wei, Ma, Shihua, Pan, Hongxing, Dai, Lianpan, Du, Pan, Wang, Lili, Jin, Lairun, Chen, Yin, Shi, Fengjuan F, Liu, Jingxian, Xu, Xiaoyu, Zhang, Yanan, Gao, George, Chen, Cancan, Feng, Jialu, Li, Jingxin, Zhu, Fengcai. Safety and immunogenicity of heterologous boost immunization with an adenovirus type-5-vectored and protein-subunit-based COVID-19 vaccine (Convidecia/ZF2001): A randomized, observer-blinded, placebo-controlled trial. PLOS MEDICINE[J]. 2022, 19(5): http://dx.doi.org/10.1371/journal.pmed.1003953.
[32] 高福. 守正出新,行稳致远. 科学通报[J]. 2022, 67(1): 1-2, http://lib.cqvip.com/Qikan/Article/Detail?id=7106585011.
[33] Xu, Zepeng, Kang, Xinrui, Han, Pu, Du, Pei, Li, Linjie, Zheng, Anqi, Deng, Chuxia, Qi, Jianxun, Zhao, Xin, Wang, Qihui, Liu, Kefang, Gao, George Fu. Binding and structural basis of equine ACE2 to RBDs from SARS-CoV, SARS-CoV-2 and related coronaviruses. NATURE COMMUNICATIONS[J]. 2022, 13(1): https://doaj.org/article/b2d7bd70a2634ce28943fb8ccea2bf04.
[34] Pei Du, George Fu Gao, Qihui Wang. The mysterious origins of the Omicron variant of SARS-CoV-2. The Innovation[J]. 2022, 3(2): 100206-4, http://lib.cqvip.com/Qikan/Article/Detail?id=7107049763.
[35] Niu, Sheng, Wang, Jia, Bai, Bin, Wu, Lili, Zheng, Anqi, Chen, Qian, Du, Pei, Han, Pengcheng, Zhang, Yanfang, Jia, Yunfei, Qiao, Chengpeng, Qi, Jianxun, Tian, WenXia, Wang, HongWei, Wang, Qihui, Gao, George Fu. Molecular basis of cross-species ACE2 interactions with SARS-CoV-2-like viruses of pangolin origin (vol 40, e107786, 2021). EMBO JOURNALnull. 2022, 41(1): [36] Shen, Yingbo, Zhang, Rong, Shao, Dongyan, Yang, Lu, Lu, Jiayue, Liu, Congcong, Wang, Xueyang, Jiang, Junyao, Wang, Boxuan, Wu, Congming, Parkhill, Julian, Wang, Yang, Walsh, Timothy R, Gao, George F, Shen, Zhangqi. Genomic Shift in Population Dynamics of mcr-1-positive Escherichia coli in Human Carriage. GENOMICS PROTEOMICS & BIOINFORMATICS[J]. 2022, 20(6): 1168-1179, http://dx.doi.org/10.1016/j.gpb.2022.11.006.
[37] 高福. 科技抗疫中的科学基金含量. 中国科学基金. 2022, 36(4): 543-543, http://lib.cqvip.com/Qikan/Article/Detail?id=7108136601.
[38] Feng, Luzhao, Zhang, Ting, Wang, Qing, Xie, Yiran, Peng, Zhibin, Zheng, Jiandong, Qin, Ying, Zhang, Muli, Lai, Shengjie, Wang, Dayan, Feng, Zijian, Li, Zhongjie, Gao, George F. Impact of COVID-19 outbreaks and interventions on influenza in China and the United States. NATURE COMMUNICATIONS[J]. 2021, 12(1): https://doaj.org/article/a8277a05a8be4c4092c4d2cf818bc855.
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[152] Tong, YiGang, Shi, WeiFeng, Liu, Di, Qian, Jun, Liang, Long, Bo, XiaoChen, Liu, Jun, Ren, HongGuang, Fan, Hang, Ni, Ming, Sun, Yang, Jin, Yuan, Teng, Yue, Li, Zhen, Kargbo, David, Dafae, Foday, Kanu, Alex, Chen, ChengChao, Lan, ZhiHeng, Jiang, Hui, Luo, Yang, Lu, HuiJun, Zhang, XiaoGuang, Yang, Fan, Hu, Yi, Cao, YuXi, Deng, YongQiang, Su, HaoXiang, Sun, Yu, Liu, WenSen, Wang, Zhuang, Wang, ChengYu, Bu, ZhaoYang, Guo, ZhenDong, Zhang, LiuBo, Nie, WeiMin, Bai, ChangQing, Sun, ChunHua, An, XiaoPing, Xu, PeiSong, Zhang, XiangLiLan, Huang, Yong, Mi, ZhiQiang, Yu, Dong, Yao, HongWu, Feng, Yong, Xia, ZhiPing, Zheng, XueXing, Yang, SongTao, Lu, Bing, Jiang, JiaFu, Kargbo, Brima, He, FuChu, Gao, George F, Cao, WuChun, China Mobile Lab Testing Team. Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone. NATURE[J]. 2015, 524(7563): 93-U191, https://www.webofscience.com/wos/woscc/full-record/WOS:000359002300038.
[153] 谭曙光, 高福. 肿瘤治疗的新希望:免疫疗法. 科学通报[J]. 2015, 60(33): 3155-3157, https://d.wanfangdata.com.cn/periodical/kxtb201533001.
[154] 高福, 冯勇, 倪伟波. 行走在塞拉利昂. 科学新闻[J]. 2015, 90-91, http://lib.cqvip.com/Qikan/Article/Detail?id=75888869504849535048485248.
[155] 高福. 蝙蝠源冠状病毒HKU4利用人CD26受体分子对MERS-CoV蝙蝠起源的提示. 科学新闻[J]. 2015, 84-84, http://lib.cqvip.com/Qikan/Article/Detail?id=663926399.
[156] Wong, Gary, Liu, Wenjun, Liu, Yingxia, Zhou, Boping, Bi, Yuhai, Gao, George F. MERS, SARS, and Ebola: The Role of Super-Spreaders in Infectious Disease. CELL HOST & MICROBEnull. 2015, 18(4): 398-401, https://www.webofscience.com/wos/woscc/full-record/WOS:000365111600007.
[157] 张必科, 高福. 掀开中国公共卫生安全的新篇章——我国首次援非抗击埃博拉. 中国科学. 生命科学[J]. 2015, 45(1): 104-106, https://www.sciengine.com/doi/10.1360/zc2015-45-1-104.
[158] 杨利敏, 李晶, 高福, 刘文军. 埃博拉病毒疫苗研究进展. 生物工程学报[J]. 2015, 31(1): 1-23, https://d.wanfangdata.com.cn/periodical/swgcxb201501001.
[159] 欧阳晶, 朱晓梅, 陈玉海, 魏海涛, 陈庆煌, 池晓娟, 祁保民, 张连峰, 赵屹, 高福, 汪国顺, 陈吉龙. 长链非编码RNANRAV在抗病毒应答中对干扰素刺激基因(ISG)转录的调控作用. 遗传[J]. 2015, 37(2): 219-219, http://lib.cqvip.com/Qikan/Article/Detail?id=664014373.
[160] 高福. 打赢埃博拉“比赛”的下半场. 科学通报[J]. 2014, 59(36): 3570-3571, https://www.sciengine.com/doi/10.1360/csb2014-59-36-3570.
[161] Gao Fu. Poultry carrying H9N2 act as incubators for novel human-infecting avian influenza viruses, (Correspondence). The Lancet. 2014, [162] Gao Fu. Crystal structure of HSV-2 gD bound to nectin-1 reveals a conserved mode of receptor recognition. Journal of Virology. 2014, [163] Gao Fu. PILRα and PILAβ have a siglec fold and provide the basis of binding to sialic acid. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2014, [164] 闫章才, 薛丽香, 李国才, 高福, 董尔丹. 流行性感冒防控基础研究状况及关键科学问题分析. 中国科学. 生命科学[J]. 2014, 44(1): 101-106, https://www.sciengine.com/doi/10.1360/N052013-00075.
[165] Shi, Yi, Wu, Ying, Zhang, Wei, Qi, Jianxun, Gao, George F. Enabling the 'host jump': structural determinants of receptor-binding specificity in influenza A viruses. NATURE REVIEWS MICROBIOLOGYnull. 2014, 12(12): 822-831, http://dx.doi.org/10.1038/nrmicro3362.
[166] 赖圣杰, , 王丽萍, 任翔, 张洪龙, 李中杰, 高福, , 余宏杰. 西非埃博拉病毒病传入中国的可能航线和风险估计. 科学通报[J]. 2014, 59(36): 3570-3580, https://d.wanfangdata.com.cn/periodical/kxtb201436007.
[167] 余宏杰, 高福. 疾控专家解读埃博拉出血热. 知识就是力量[J]. 2014, 46-47, http://lib.cqvip.com/Qikan/Article/Detail?id=90837676504849524857484956.
[168] 李昱, 任翔, 刘翟, 程颖, 高福, 余宏杰. 埃博拉病毒病:流行病学、生态学、诊断、治疗及控制. 科技导报[J]. 2014, 32(24): 15-24, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5232947&detailType=1.
[169] 高福. 维护疫苗免疫规划实践, 建立疫苗不良反应数据库. 中国科学. 生命科学[J]. 2014, 44(5): 512-513, https://www.sciengine.com/doi/10.1360/zc2014-44-5-512.
[170] Gao Fu. Influenza and the live poultry trade, (Editorial). Science. 2014, [171] Guanghua Xu, Jing Wang, George Fu Gao, Cui Hua Liu. nsights into battles between Mycobacterium tuberculosis and macrophages. 蛋白质与细胞:英文版[J]. 2014, 728-736, http://lib.cqvip.com/Qikan/Article/Detail?id=663125373.
[172] Wu, Ying, Wu, Yan, Tefsen, Boris, Shi, Yi, Gao, George F. Bat-derived influenza-like viruses H17N10 and H18N11. TRENDS IN MICROBIOLOGYnull. 2014, 22(4): 183-191, http://dx.doi.org/10.1016/j.tim.2014.01.010.
[173] Sun, Xiaoman, Li, Qing, Wu, Yan, Wang, Mingyang, Liu, Yue, Qi, Jianxun, Vavricka, Christopher J, Gao, George F. Structure of Influenza Virus N7: the Last Piece of the Neuraminidase "Jigsaw" Puzzle. JOURNAL OF VIROLOGY[J]. 2014, 88(16): 9197-9207, http://dx.doi.org/10.1128/JVI.00805-14.
[174] Tefsen, Boris, Lu, Guangwen, Zhu, Yaohua, Haywood, Joel, Zhao, Lili, Deng, Tao, Qi, Jianxun, Gao, George F. The N-Terminal Domain of PA from Bat-Derived Influenza-Like Virus H17N10 Has Endonuclease Activity. JOURNAL OF VIROLOGY[J]. 2014, 88(4): 1935-1941, http://dx.doi.org/10.1128/JVI.03270-13.
[175] Gao Fu. On the ground in Sierra Leone, (Working Life). SCIENCE. 2014, [176] 冯长根, 邓中翰, 谢克昌, 黄伯云, 杨乐, 秦大河, 唐启升, 沈岩, 谢和平. 不妨多办几个“清华”“北大”促进地方发展. 科技导报. 2014, 32(18): 12-, https://d.wanfangdata.com.cn/periodical/kjdb201418005.
[177] Wang, Qihui, Qi, Jianxun, Yuan, Yuan, Xuan, Yifang, Han, Pengcheng, Wan, Yuhua, Ji, Wei, Li, Yan, Wu, Ying, Wang, Jianwei, Iwamoto, Aikichi, Woo, Patrick C Y, Yuen, KwokYung, Yan, Jinghua, Lu, Guangwen, Gao, George F. Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26. CELL HOST & MICROBE[J]. 2014, 16(3): 328-337, http://www.corc.org.cn/handle/1471x/2157676.
[178] 高福. Dynamic reassortments and genetic heterogeneity of the human-infecting influenza A (H7N9) virus. NATURE COMMUNICATIONS[J]. 2014, 5: 3142-, https://www.webofscience.com/wos/woscc/full-record/WOS:000331097100006.
[179] Sun, Mingwei, Liu, Jun, Qi, Jianxun, Tefsen, Boris, Shi, Yi, Yan, Jinghua, Gao, George F. N-alpha-Terminal Acetylation for T Cell Recognition: Molecular Basis of MHC Class I-Restricted N-alpha-Acetylpeptide Presentation. JOURNAL OF IMMUNOLOGY[J]. 2014, 192(12): 5509-5519, https://www.webofscience.com/wos/woscc/full-record/WOS:000337172100010.
[180] Jing Ouyang, Xiaomei Zhu, Yuhai Chen, Haitao Wei, Qinghuang Chen, Xiaojuan Chi, Baomin Qi, Lianfeng Zhang, Yi Zhao, George Fu Gao, Guoshun Wang, JiLong Chen. NRAV, a Long Noncoding RNA, Modulates Antiviral Responses through Suppression of Interferon-Stimulated Gene Transcription. CELL HOST & MICROBE[J]. 2014, 616-626, https://www.webofscience.com/wos/woscc/full-record/WOS:000345123900012.
[181] 逯光文, 吴莹, 高福. 高致病性中东呼吸综合征冠状病毒识别细胞受体分子机制的破译. 中国细胞生物学学报[J]. 2014, 36(1): 1-4, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5041181&detailType=1.
[182] Lu, Xishan, Qi, Jianxun, Shi, Yi, Wang, Ming, Smith, David F, HeimburgMolinaro, Jamie, Zhang, Yanfang, Paulson, James C, Xiao, Haixia, Gao, George F. Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6. JOURNAL OF VIROLOGY[J]. 2013, 87(16): 9077-9085, http://dx.doi.org/10.1128/JVI.00235-13.
[183] Gao Fu. Origin and diversity of novel H7N9 avian influenza viruses causing human infecions. The Lancet. 2013, [184] 高福. Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. THE LANCET. 2013, 381(9881): 1926-32, [185] Zhang, Shuijun, Lu, Guangwen, Qi, Jianxun, Li, Yan, Zhang, Zhiyang, Zhang, Buchang, Fan, Zheng, Yan, Jinghua, Gao, George F. Competition of Cell Adhesion and Immune Recognition: Insights into the Interaction between CRTAM and Nectin-like 2. STRUCTURE[J]. 2013, 21(8): 1430-1439, http://www.corc.org.cn/handle/1471x/2157443.
[186] 高福. An airborne transmissible avian influenza H5 hemagglutinin seen at the atomic level. SCIENCE[J]. 2013, 340(6139): 1463-1467, https://www.webofscience.com/wos/woscc/full-record/WOS:000320647000045.
[187] 高福. Structures and Receptor Binding of Hemagglutinins from Human-Infecting H7N9 Influenza Viruses. SCIENCE[J]. 2013, 342(6155): 243-247, http://124.16.173.210/handle/834782/1268.
[188] 於方, 马国霞, 张衍燊, 曹东, 高福, 王金南. 中国大气污染健康影响评估若干问题. 中华医学杂志[J]. 2013, 93(34): 2695-2698, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=4925562&detailType=1.
[189] Gao Fu. Structure of the fusion core and inhibition of fusion by a heptad-repeat peptide derived from the S protein of MERS-CoV. Journal of Virology. 2013, [190] Sun, Xiaoman, Shi, Yi, Lu, Xishan, He, Jianhua, Gao, Feng, Yan, Jinghua, Qi, Jianxun, Gao, George F. Bat-Derived Influenza Hemagglutinin H17 Does Not Bind Canonical Avian or Human Receptors and Most Likely Uses a Unique Entry Mechanism. CELL REPORTS[J]. 2013, 3(3): 769-778, http://dx.doi.org/10.1016/j.celrep.2013.01.025.
[191] 高福. Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors. NATURE COMMUNICATIONS[J]. 2013, 4: 1491-, [192] Zhang, Wei, Shi, Yi, Qi, Jianxun, Gao, Feng, Li, Qing, Fan, Zheng, Yan, Jinghua, Gao, George F. Molecular Basis of the Receptor Binding Specificity Switch of the Hemagglutinins from both the 1918 and 2009 Pandemic Influenza A Viruses by a D225G Substitution. JOURNAL OF VIROLOGY[J]. 2013, 87(10): 5949-5958, http://www.irgrid.ac.cn/handle/1471x/756483.
[193] 高福. Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. NATURE[J]. 2013, 500(7461): 227-+, http://dx.doi.org/10.1038/nature12328.
[194] Gao Fu. Functional and structural analysis of influenza neuraminidase N3 offers further insight into the mechanisms of oseltamivir-resistance. Journal of Virology. 2013, [195] 高福. Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4. NATURE STRUCTURAL & MOLECULAR BIOLOGY[J]. 2013, 20(1): 67-U86, https://www.webofscience.com/wos/woscc/full-record/WOS:000313072400012.
[196] Wu Yan, Bi Yuhai, Vavricka Christopher J, Sun Xiaoman, Zhang Yanfang, Gao Feng, Zhao Min, Xiao Haixia, Qin Chengfeng, He Jianhua, Liu Wenjun, YAN, JINGHUA, Qi Jianxun, Gao George F. Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses. CELL RESEARCH[J]. 2013, 23(12): 1347-1355, http://124.16.173.210/handle/834782/1226.
[197] Liu, Cui Hua, Li, Hong Min, Lu, Na, Wang, Qi, Hu, Yong Liang, Yang, Xi, Hu, Yong Fei, Woo, Patrick C Y, Gao, George F, Zhu, Baoli. Genomic sequence based scanning for drug resistance-associated mutations and evolutionary analysis of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis. JOURNAL OF INFECTION[J]. 2012, 65(5): 412-422, http://dx.doi.org/10.1016/j.jinf.2012.06.007.
[198] 刘军, 齐建勋, 高峰, 严景华, 高福. T细胞功能学与结构免疫学结合方法鉴定HLA—A2限制性的细胞毒性T淋巴细胞表位富集区. 生理通讯[J]. 2012, 31(1): 8-16, http://lib.cqvip.com/Qikan/Article/Detail?id=42413246.
[199] 刘传省, 施一, 高福. HLA-A*2402多肽复合物的两种构象——对Wolynes理论的补充. 生物工程学报[J]. 2012, 28(11): 1370-1377, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=4677087&detailType=1.
[200] Gao Fu. Reply to Nuclear export signal and immunodominant CD8+ T cell epitope in influenza A virus matrix protein 1--Sequence sharing between viral nuclear export signals (NES) and CD8+ T cell epitopes. Journal of Virology. 2012, [201] Li, Bin, Yi, Yong, Wang, Qi, Woo, Patrick C Y, Tan, Lin, Jing, Hua, Gao, George F, Liu, Cui Hua. Analysis of Drug Resistance Determinants in Klebsiella pneumoniae Isolates from a Tertiary-Care Hospital in Beijing, China. PLOS ONE[J]. 2012, 7(7): http://dx.doi.org/10.1371/journal.pone.0042280.
[202] Zhang, Wen, Rong, Chengbo, Chen, Chen, Gao, George F. Type-IVC Secretion System: A Novel Subclass of Type IV Secretion System (T4SS) Common Existing in Gram-Positive Genus Streptococcus. PLOS ONE[J]. 2012, 7(10): https://doaj.org/article/42f5a2bd08c24361a2ad7af76d2f2004.
[203] Liu, Jun, Zhang, Shihong, Tan, Shuguang, Yi, Yong, Wu, Bin, Cao, Bin, Zhu, Fengcai, Wang, Chen, Wang, Hua, Qi, Jianxun, Gao, George F. Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals. JOURNAL OF VIROLOGY[J]. 2012, 86(24): 13281-13294, https://www.webofscience.com/wos/woscc/full-record/WOS:000311299600013.
[204] 高福. Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2012, 109(46): 18897-18902, [205] Han, Huiming, Liu, Cuihua, Wang, Quanhui, Xuan, Chunling, Zheng, Beiwen, Tang, Jiaqi, Yan, Jinghua, Zhang, Jingren, Li, Ming, Cheng, Hao, Lu, Guangwen, Gao, George F. The two-component system Ihk/Irr contributes to the virulence of Streptococcus suis serotype 2 strain 05ZYH33 through alteration of the bacterial cell metabolism. MICROBIOLOGY-SGM[J]. 2012, 158: 1852-1866, http://dx.doi.org/10.1099/mic.0.057448-0.
[206] Liu, Jun, Qian, Xiaomin, Chen, Zhujun, Xu, Xiang, Gao, Feng, Zhang, Shuijun, Zhang, Rongguang, Qi, Jianxun, Gao, George F, Yan, Jinghua. Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226. JOURNALOFIMMUNOLOGY[J]. 2012, 188(11): 5511-5520, http://dx.doi.org/10.4049/jimmunol.1200324.
[207] Gao Fu. Insights into avian influenza virus pathogenicity: the hemagglutinin precursor HA0 of H16 subtype has an a-helix structure in its cleavage site with an inefficient HA1/HA2 cleavage. Journal of Virology. 2012, [208] Lu, Qiong, Lu, Hao, Qi, Jianxun, Lu, Guangwen, Gao, George F. An octamer of enolase from Streptococcus suis. PROTEIN & CELL[J]. 2012, 3(10): 769-780, http://124.16.173.210/handle/834782/1302.
[209] Zhang, Jianhua, Chen, Yong, Qi, Jianxun, Gao, Feng, Liu, Yanjie, Liu, Jun, Zhou, Xuyu, Kaufman, Jim, Xia, Chun, Gao, George F. Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens. JOURNAL OF IMMUNOLOGY[J]. 2012, 189(9): 4478-4487, http://www.irgrid.ac.cn/handle/1471x/756866.
[210] Liu, Peipei, Lu, Hao, Li, Shuang, Moureau, Gregory, Deng, YongQiang, Wang, Yongyue, Zhang, Lijiao, Jiang, Tao, de Lamballerie, Xavier, Qin, ChengFeng, Gould, Ernest A, Su, Jingliang, Gao, George F. Genomic and antigenic characterization of the newly emerging Chinese duck egg-drop syndrome flavivirus: genomic comparison with Tembusu and Sitiawan viruses. JOURNAL OF GENERAL VIROLOGY[J]. 2012, 93: 2158-2170, http://dx.doi.org/10.1099/vir.0.043554-0.
[211] Liu. Membrane Protein of SARS-CoV Acts as a Dominant Immunogen Revealed by a Clustering Region of Novel Functional and Structural Defined CTL Epitopes (vol 202, pg 1171, 2010). JOURNAL OF INFECTIOUS DISEASESnull. 2011, 203(11): 1699-1699, https://www.webofscience.com/wos/woscc/full-record/WOS:000290858800031.
[212] Lu, Guangwen, Qi, Jianxun, Gao, Feng, Yan, Jinghua, Tang, Jiaqi, Gao, George F. A novel "open-form" structure of sortaseC from Streptococcus suis. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS[J]. 2011, 79(9): 2764-2769, http://www.irgrid.ac.cn/handle/1471x/757501.
[213] Shi, Yi, Qi, Jianxun, Iwamoto, Aikichi, Gao, George F. Plasticity of human CD8 alpha alpha binding to peptide-HLA-A*2402. MOLECULARIMMUNOLOGY[J]. 2011, 48(15-16): 2198-2202, https://www.webofscience.com/wos/woscc/full-record/WOS:000295395300054.
[214] Liu, Jun, Zhang, Shihong, Tan, Shuguang, Zheng, Beiwen, Gao, George F. Revival of the identification of cytotoxic T-lymphocyte epitopes for immunological diagnosis, therapy and vaccine development. EXPERIMENTAL BIOLOGY AND MEDICINEnull. 2011, 236(3): 253-267, https://www.webofscience.com/wos/woscc/full-record/WOS:000295201200002.
[215] Wang, Mingyang, Qi, Jianxun, Liu, Yue, Vavricka, Christopher J, Wu, Yan, Li, Qing, Gao, George F. Influenza A Virus N5 Neuraminidase Has an Extended 150-Cavity. JOURNAL OF VIROLOGY[J]. 2011, 85(16): 8431-8435, http://dx.doi.org/10.1128/JVI.00638-11.
[216] Li, Ming, Shen, Xiaodong, Yan, Jinghua, Han, Huiming, Zheng, Beiwen, Liu, Di, Cheng, Hao, Zhao, Yan, Rao, Xiancai, Wang, Changjun, Tang, Jiaqi, Hu, Fuquan, Gao, George F. GI-type T4SS-mediated horizontal transfer of the 89K pathogenicity island in epidemic Streptococcus suis serotype 2. MOLECULAR MICROBIOLOGY[J]. 2011, 79(6): 1670-1683, http://dx.doi.org/10.1111/j.1365-2958.2011.07553.x.
[217] Hu, Xudong, Liu, Di, Wang, Mingyang, Yang, Le, Wang, Ming, Zhu, Qingyu, Li, Laixing, Gao, George F. Clade 2.3.2 Avian Influenza Virus (H5N1), Qinghai Lake Region, China, 2009-2010. EMERGING INFECTIOUS DISEASES. 2011, 17(3): 560-562, http://ir.nwipb.ac.cn/handle/363003/1579.
[218] 孙明伟, 路希山, 高福. 合成病毒:对流感病毒研究的贡献. 生命科学[J]. 2011, 23(9): 921-930, http://lib.cqvip.com/Qikan/Article/Detail?id=39442219.
[219] Gao Fu. An infectious clone of the highly pathogenic porcine reproductive and respiratory syndrome virus: topology of glycoprotein 3 (GP3) addressing the intrachain disulfide bonds; PRRSV infectious clone and GP3 topology. Chinese Science Bulletin. 2011, [220] Cheng, Hao, Mohammed, Fiyaz, Nam, Gol, Chen, Yong, Qi, Jianxun, Garner, Lee I, Allen, Rachel L, Yan, Jinghua, Willcox, Benjamin E, Gao, George F. Crystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k) A MYELOID INHIBITORY RECEPTOR INVOLVED IN IMMUNE TOLERANCE. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2011, 286(20): 18013-18025, http://dx.doi.org/10.1074/jbc.M111.221028.
[221] Zhang Yudan, Cao Sheng, Meng Songdong, Gao, George Fu. A strategy to produce monoclonal antibodies against gp96 by prime-boost regimen using endogenous protein and E. coli heterologously-expressed fragment. JOURNAL OF CENTRAL SOUTH UNIVERSITY OF TECHNOLOGY[J]. 2011, 18(6): 1857-1864, http://lib.cqvip.com/Qikan/Article/Detail?id=40231943.
[222] Lu, Guangwen, Qi, Jianxun, Chen, Zhujun, Xu, Xiang, Gao, Feng, Lin, Daizong, Qian, Wangke, Liu, Hong, Jiang, Hualiang, Yan, Jinghua, Gao, George F. Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design. JOURNAL OF VIROLOGY[J]. 2011, 85(19): 10319-10331, http://www.irgrid.ac.cn/handle/1471x/757510.
[223] Gao Fu. Two distinct conformations of a CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801: a host strategy for presentation of a featured peptide. Journal of Virology. 2011, [224] Feng ChunYan, Gao Feng, Liu YiWei, Wang GuiHua, Peng Hao, Ma YanHe, Yan JingHua, Gao George Fu. Crystal structure of histidine-containing phosphocarrier protein from Thermoanaerobacter tengcongensis MB4 and the implications for thermostability. SCIENCE CHINA-LIFE SCIENCES[J]. 2011, 54(6): 513-519, http://dx.doi.org/10.1007/s11427-011-4182-x.
[225] Liao Hui, Liu Cuihua, Yang Ruifu, Jiang Yongqiang, Zhang Ruifen, Lu Na, Li Jing, Wang Changjun, Li Ming, Wu Zuowei, Gao George F, Tang Jiaqi, Zhu Baoli. Probing genomic diversity and evolution of Streptococcus suis serotype 2 by NimbleGen tiling arrays. BMC GENOMICS[J]. 2011, 12(1): https://doaj.org/article/438bb56fefb742c4b5b9b0bd68efbd8f.
[226] Gao Fu. Special features of the 2009 pandemic swine-origin influenza A H1N1 hemagglutinin and neuraminidase (invited review). Chinese Science Bulletin. 2011, [227] Du, Pengcheng, Yang, Yinxue, Wang, Haiying, Liu, Di, Gao, George F, Chen, Chen. A large scale comparative genomic analysis reveals insertion sites for newly acquired genomic islands in bacterial genomes. BMC MICROBIOLOGY[J]. 2011, 11(1): 135-135, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201706298530813ZK.
[228] Zhang, Nianzhi, Qi, Jianxun, Feng, Sijia, Gao, Feng, Liu, Jun, Pan, Xiaocheng, Chen, Rong, Li, Qirun, Chen, Zhaosan, Li, Xiaoying, Xia, Chun, Gao, George F. Crystal Structure of Swine Major Histocompatibility Complex Class I SLA-1*0401 and Identification of 2009 Pandemic Swine-Origin Influenza A H1N1 Virus Cytotoxic T Lymphocyte Epitope Peptides. JOURNAL OF VIROLOGY[J]. 2011, 85(22): 11709-11724, http://dx.doi.org/10.1128/JVI.05040-11.
[229] Myongchol Ryu, Yong Chen, Jianxun Qi, Jun Liu, Zheng Fan, Gol Nam, Yi Shi, Hao Cheng, George F Gao. LILRA3 Binds Both Classical and Non-Classical HLA Class I Molecules but with Reduced Affinities Compared to LILRB1/LILRB2: Structural Evidence. PLOS ONE[J]. 2011, 6(4): https://doaj.org/article/771283f228424e01bb492484c8ea81d9.
[230] 刘军, 齐建勋, 高福, 严景华, 高福. T细胞功能学与结构免疫学结合方法鉴定HLA-A2限制性的细胞毒性T淋巴细胞表位富集区. 科技导报[J]. 2011, 29(27): 19-26, http://lib.cqvip.com/Qikan/Article/Detail?id=39427917.
[231] Zheng, Beiwen, Zhang, Qiangmin, Gao, Jia, Han, Huiming, Li, Ming, Zhang, Jingren, Qi, Jianxun, Yan, Jinghua, Gao, George F. Insight into the Interaction of Metal Ions with TroA from Streptococcus suis. PLOS ONE[J]. 2011, 6(5): http://dx.doi.org/10.1371/journal.pone.0019510.
[232] Su, Jingliang, Li, Shuang, Hu, Xudong, Yu, Xiuling, Wang, Yongyue, Liu, Peipei, Lu, Xishan, Zhang, Guozhong, Hu, Xueying, Liu, Di, Li, Xiaoxia, Su, Wenliang, Lu, Hao, Mok, Ngai Shing, Wang, Peiyi, Wang, Ming, Tian, Kegong, Gao, George F. Duck Egg-Drop Syndrome Caused by BYD Virus, a New Tembusu-Related Flavivirus. PLOS ONE[J]. 2011, 6(3): http://dx.doi.org/10.1371/journal.pone.0018106.
[233] Zhang, Shihong, Liu, Jun, Cheng, Hao, Tan, Shuguang, Qi, Jianxun, Yan, Jinghua, Gao, George F. Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes. MOLECULAR IMMUNOLOGY[J]. 2011, 49(1-2): 395-401, http://dx.doi.org/10.1016/j.molimm.2011.08.015.
[234] 高福. Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion. NATURE COMMUNICATIONS[J]. 2011, 2: 577-, http://www.corc.org.cn/handle/1471x/2200832.
[235] Yueju Zhao, Yunhua Zhang, Yang Cao, Jianxun Qi, Liangwei Mao, Yanfen Xue, Feng Gao, Hao Peng, Xiaowei Wang, George F Gao, Yanhe Ma. Structural analysis of alkaline β-mannanase from alkaliphilic Bacillus sp. N16-5: implications for adaptation to alkaline conditions.. PLOS ONE[J]. 2011, 6(1): https://doaj.org/article/35b533dcd489420b977445527f302821.
[236] Wu, Yan, Gao, Feng, Liu, Jun, Qi, Jianxun, Gostick, Emma, Price, David A, Gao, George F. Structural Basis of Diverse Peptide Accommodation by the Rhesus Macaque MHC Class I Molecule Mamu-B*17: Insights into Immune Protection from Simian Immunodeficiency Virus. JOURNAL OF IMMUNOLOGY[J]. 2011, 187(12): 6382-6392, http://dx.doi.org/10.4049/jimmunol.1101726.
[237] 高福. Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition. PLOS PATHOGENS[J]. 2011, 7(10): e1002249-, http://dx.doi.org/10.1371/journal.ppat.1002249.
[238] 胡旭东, 路浩, 刘培培, 遇秀玲, 李爽, 王勇月, 莫毅诚, 张国中, 田克恭, 高福, 苏敬良. 我国发现的一种引起鸭产蛋下降综合征的新型黄病毒. 中国兽医杂志[J]. 2011, 47(7): 43-47, http://lib.cqvip.com/Qikan/Article/Detail?id=38801996.
[239] Zengfu Wang, Xiaoling Liu, Zhendong Zhao, Chongfeng Xu, Ke Zhang, Caiwei Chen, Lei Sun, George F Gao, Xin Ye, Wenjun Liu. Cyclophilin E Functions as a Negative Regulator to Influenza Virus Replication by Impairing the Formation of the Viral Ribonucleoprotein Complex. PLOS ONE[J]. 2011, 6(8): https://doaj.org/article/5b052dc924e54ad580b675f6edbe0ffe.
[240] 张誉丹, 操胜, 孟颂东, 高福. A strategy to produce monoclonal antibodies against gp96 by prime-boost regimen using endogenous protein and E. coli heterologously-expressed fragment. 中南大学学报:英文版[J]. 2011, 18(6): 1857-1864, http://lib.cqvip.com/Qikan/Article/Detail?id=40231943.
[241] Liu, Jun, Dai, Lianpan, Qi, Jianxun, Gao, Feng, Feng, Youjun, Liu, Wenjun, Yan, Jinghua, Gao, George F. Diverse Peptide Presentation of Rhesus Macaque Major Histocompatibility Complex Class I Mamu-A*02 Revealed by Two Peptide Complex Structures and Insights into Immune Escape of Simian Immunodeficiency Virus. JOURNAL OF VIROLOGY[J]. 2011, 85(14): 7372-7383, http://dx.doi.org/10.1128/JVI.00350-11.
[242] 孙明伟, 高福. 小议2010国内外生命科学重要进展. 遗传[J]. 2011, 33(2): 97-99, http://lib.cqvip.com/Qikan/Article/Detail?id=37086293.
[243] 刘军, 齐建勋, 高峰, 严景华, 高福. T细胞功能学与结构免疫学结合方法鉴定HLA-A2限制性的细胞毒性T淋巴细胞表位富集区. 科技导报[J]. 2011, 29(27): 19-26, http://lib.cqvip.com/Qikan/Article/Detail?id=39427917.
[244] 孙明伟, 李寅, 高福. 从人类基因组到人造生命:克雷格·文特尔领路生命科学. 新华文摘[J]. 2010, 138-141, http://lib.cqvip.com/Qikan/Article/Detail?id=35072215.
[245] Gao Fu. Novel immunodominant peptide presentation strategy: a featured HLA-A*2402 restricted CTL-epitope stabilized by intra-chain hydrogen-bonds from SARS-CoV N protein. Journal of Virology. 2010, [246] 孙明伟, 郑焙文, 高福, 朱宝利. 人类与病原菌的军备竞赛:NDM-1耐药基因与超级细菌. 生物工程学报[J]. 2010, 1461-1472, http://lib.cqvip.com/Qikan/Article/Detail?id=35968914.
[247] 孙业平, 高福. 天然免疫抗病毒效应分子Mx蛋白的结构与功能研究进展. 生物化学与生物物理进展[J]. 2010, 37(7): 699-706, http://lib.cqvip.com/Qikan/Article/Detail?id=34772339.
[248] Zhang, Wei, Qi, Jianxun, Shi, Yi, Li, Qing, Gao, Feng, Sun, Yeping, Lu, Xishan, Lu, Qiong, Vavricka, Christopher J, Liu, Di, Yan, Jinghua, Gao, George F. Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus. PROTEIN & CELL[J]. 2010, 1(5): 459-467, http://www.corc.org.cn/handle/1471x/2374127.
[249] Lu, Lu, Yin, Yanbo, Sun, Zhongsheng, Gao, Lei, Gao, George F, Liu, Sidang, Sun, Lei, Liu, Wenjun. Genetic correlation between current circulating H1N1 swine and human influenza viruses. JOURNAL OF CLINICAL VIROLOGY[J]. 2010, 49(3): 186-191, http://dx.doi.org/10.1016/j.jcv.2010.07.018.
[250] 李青, 冯恩光, 柳红, 高福. 基于结构的抗流感病毒神经氨酸酶抑制剂的设计和研发. 生物产业技术[J]. 2010, 42-48, http://lib.cqvip.com/Qikan/Article/Detail?id=36042227.
[251] Cai Qi, Xin-Sheng Tian, She Chen, Jing-Hua Yan, Zhen Cao, Ke-Gong Tian, George F. Gao, Gang Jin. Detection of avian influenza virus subtype H5 using a biosensor based on imaging ellipsometry. BIOSENSORS AND BIOELECTRONICS. 2010, 25(6): 1530-1534, http://dx.doi.org/10.1016/j.bios.2009.10.030.
[252] Mi ShuoFu, Li Yan, Yan JingHua, Gao George Fu. Na+/K+-ATPase beta 1 subunit interacts with M2 proteins of influenza A and B viruses and affects the virus replication. SCIENCE CHINA-LIFE SCIENCES[J]. 2010, 53(9): 1098-1105, http://124.16.144.217/handle/311023/3692.
[253] Chen, Yong, Liu, Peipei, Gao, Feng, Cheng, Hao, Qi, Jianxun, Gao, George F. A dimeric structure of PD-L1: functional units or evolutionary relics?. PROTEIN & CELL[J]. 2010, 1(2): 153-160, http://www.corc.org.cn/handle/1471x/2406038.
[254] Gao, George F, Sun YePing. It is not just AIV: From avian to swine-origin influenza virus. SCIENCE CHINA-LIFE SCIENCES[J]. 2010, 53(1): 151-153, https://www.webofscience.com/wos/woscc/full-record/WOS:000276437700020.
[255] Cui, Jia, Chen, Qiuyue, Yue, Xiaojing, Jiang, Xuejun, Gao, George F, Yu, LongChuan, Zhang, Yan. Galanin Protects Against Intracellular Amyloid Toxicity in Human Primary Neurons. JOURNAL OF ALZHEIMERS DISEASE[J]. 2010, 19(2): 529-544, http://dx.doi.org/10.3233/JAD-2010-1246.
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[257] 安敏, 高福, 齐建勋, 李锋, 刘杏忠. 灵芝免疫调节蛋白LZ-8的制备和晶体分析. 生物工程学报[J]. 2010, 1563-1568, http://lib.cqvip.com/Qikan/Article/Detail?id=35968927.
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[260] Zhang, Xiaoxue, Gao, George F. Revival of gene therapy. PROTEIN & CELL[J]. 2010, 1(2): 107-108, https://www.webofscience.com/wos/woscc/full-record/WOS:000208510400001.
[261] Gao Fu. In-silicon characterization of the functional and structural modules of the haemagglutinin protein from the swine-origin influenza virus A (H1N1)-2009. Science China Life Sciences. 2010, [262] 高福. The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site. NATURE STRUCTURAL & MOLECULAR BIOLOGY[J]. 2010, 17(10): 1266-1268, http://dx.doi.org/10.1038/nsmb.1909.
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[269] Gao Fu. Avian influenza virus, Streptococcus suis serotype 2, SARS-coronavirus and beyond: molecular epidemiology, ecology and the situation in China. Philosophical Transactions of the Royal Society B (Biological Sciences). 2009, [270] Guo, Ying, RumschlagBooms, Emily, Wang, Jizhen, Xiao, Haixia, Yu, Jia, Wang, Jianwei, Guo, Li, Gao, George F, Cao, Youjia, Caffrey, Michael, Rong, Lijun. Analysis of hemagglutinin-mediated entry tropism of H5N1 avian influenza. VIROLOGY JOURNAL[J]. 2009, 6(1): https://doaj.org/article/ec3e1ffa58f84fbda078302ea7cdf004.
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[273] Zong, Lili, Chen, Yong, Peng, Hao, Gao, Feng, Iwamoto, Aikichi, Gao, George F. Rhesus macaque: A tight homodimeric CD8 alpha alpha. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS[J]. 2009, 75(1): 241-244, http://dx.doi.org/10.1002/prot.22331.
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[284] 宋晓晖, 胡旭东, 马素芳, 王明旸, 张蔚, 马颖, 陈越, 马广鹏, 汪明, 杨希才, 刘文军, 刘金华, 田波, 刘翟, 严景华, 高福. 动物源性流感病毒与人流感流行. 科技导报[J]. 2009, 19-24, http://lib.cqvip.com/Qikan/Article/Detail?id=30360913.
[285] 尹捷, 刘一苇, 李洁, 马延和, 向华, 严景华, 高福. 腾冲嗜热厌氧杆菌6-磷酸-β-葡萄糖苷酶的表达与结晶及其功能鉴定. 中国生物化学与分子生物学报[J]. 2008, 24(10): 916-924, http://lib.cqvip.com/Qikan/Article/Detail?id=28481327.
[286] ZHANG YiPing, GAO FU, HE DaMing, LI ShaoJuan. Comparison of spatial-temporal distribution characteristics of water temperatures between Lancang River and Mekong River. 中国科学通报:英文版[J]. 2007, 52(A02): 141-147, http://lib.cqvip.com/Qikan/Article/Detail?id=26800873.
[287] 高福. 中医的英译和自我认识. 科技导报[J]. 2007, 25(12): 74-74, http://lib.cqvip.com/Qikan/Article/Detail?id=24883262.
[288] Zhang YiPing, Gao Fu, He DaMing, Li ShaoJuan. Comparison of spatial-temporal distribution characteristics of water temperatures between Lancang River and Mekong River. CHINESE SCIENCE BULLETIN[J]. 2007, 52: 141-147, http://lib.cqvip.com/Qikan/Article/Detail?id=26800873.
[289] 高福. 高福:新春伊始严防禽流感. 中国科学院院刊[J]. 2006, 21(2): 95-, http://lib.cqvip.com/Qikan/Article/Detail?id=21456152.
[290] 高福, 黄力, 谭华荣. 微生物学案头百科. 2006, 1149-, http://124.16.144.217/handle/311023/4354.
[291] 冯友军, 高福. 平淡世界里的精彩——评2005年诺贝尔生理学与医学奖. 自然杂志[J]. 2005, 27(6): 330-332, http://lib.cqvip.com/Qikan/Article/Detail?id=20790402.
[292] 高福. 怎样做好科研工作. 科学中国人[J]. 2005, 38-39, http://lib.cqvip.com/Qikan/Article/Detail?id=11661862.
[293] 校海霞, 褚福亮, 高福. 青海湖禽流感-暴风雨来临前的信号. 传染病信息[J]. 2005, 18(4): 172-172, http://lib.cqvip.com/Qikan/Article/Detail?id=20834829.
[294] 校海霞, 高福. 一个迫近的危险的信号——大批候鸟死于H5N1亚型高致病性禽流感. 自然杂志[J]. 2005, 27(6): 322-322,329, http://lib.cqvip.com/Qikan/Article/Detail?id=20790399.
[295] 高福, 田波, 王春平, 朱杰青, 康云. FIV gp40七肽重复区基因的克隆表达及其产物的纯化. 中国病毒学[J]. 2004, 19(1): 22-26, http://lib.cqvip.com/Qikan/Article/Detail?id=9157915.
[296] 高福, 田波, 朱杰青, 肖庚富. 抑制SARS冠状病毒的多肽药物及其衍生物. 科技开发动态[J]. 2004, 32-32, http://lib.cqvip.com/Qikan/Article/Detail?id=11408116.
[297] 李燕, 孟颂东, 陈溥言, 高福, 田波. 马立克氏病毒感染的鸡肝脏肿瘤中热应激蛋白108含量的增高及其基因序列分析和表达的研究. 自然科学进展[J]. 2003, 13(7): 698-702, http://lib.cqvip.com/Qikan/Article/Detail?id=8077012.
[298] 陈永福, 刘金华, 郭玉璞, 史为民, 高福, 杨汉春. 乙脑病毒PrME基因在杆状病毒表达系统中的表达. 畜牧兽医学报[J]. 1998, 29(6): 546-, http://lib.cqvip.com/Qikan/Article/Detail?id=3202744.
[299] 狄伯雄, 高福. 白唇鹿的肠毒血症. 野生动物[J]. 1989, 39-39, http://lib.cqvip.com/Qikan/Article/Detail?id=3001467164.
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发表著作
(1) 免疫学前沿进展 (第二版) 第七章: 结构免疫学研究进展: 主要组织相容性复合物的分子识别,Frontier Progress of Immunology (Edition 2) Chapter 7 Research Progress of Sructural Immunology: Molecular Recognition of Major Histocompatibility Complex ,人民卫生出版社,2011-12,第3作者
(2) 主要组织相容性复合物与多肽的相互作用,Major Histocompatibility Complex: Interaction with Peptides,John Wiley and Sons, Ltd,2011-08,第2作者
(3) 应用于健康、环境及生物安全的生物传感器 第七章:应用于人类健康的无标记生物传感器,Biosensors for Health, Environment and Biosecurity Chapter 7: Label-free Biosensors for Health Applications,InTech,2011-07,第1作者
(4) 免疫学前沿进展(第一版) 第六章: 结构免疫学研究进展: 主要组织相容性复合物的分子识别,Frontier Progress of Immunology (Edition 1) Chapter 6 Research Progress of Sructural Immunology: Molecular Recognition of Major Histocompatibility Complex ,人民卫生出版社,2009-12,第3作者

科研活动

   
科研项目
(1) Follow-up of Surveillance of the Wild Birds and Pl,主持,其他级,2011-12--2012-11
(2) 新型免疫细胞δβ T细胞识别配体的功能和结构基础,主持,部委级,2011-01--2014-12
(3) 重要病毒跨种间感染与传播致病的分子机制研究,主持,部委级,2011-01--2015-12
(4) 病原微生物与宿主互作的分子机制,主持,部委级,2011-01--2013-12
(5) 获得性免疫的起源与演化,参与,部委级,2011-01--2013-12
参与会议
(1) Special characteristics of the 2009-pandemic H1N1 influenza A virus hemagglutinin and neuraminidase,2012-04,高福
(2) Nectin and nectin-like molecules: Adhesion, immune,2012-04,高福
(3) 2009 Pandemic influenza virus: what special for its HA and NA,2012-01,高福
(4) Making the CTL-epitopes featured for T cell recognition,2011国际免疫暨肿瘤研讨会,2011-12,高福
(5) 创新:永远的追求——我所认识的田波院士,第九届全国病毒学学术研讨会,2011-09,高福
(6) 分会主席,2011-09,分会主席
(7) ILT: Differential Binding to HLA,第二届海峡两岸四地免疫学研讨会,2011-08,高福
(8) T-cell-based immunotherapy,第五届中国生物产业大会,2011-06,高福
(9) 2009 Pandemic influenza virus: what special for its HA and NA,2011-06,高福
(10) Study of CTL-based cellular immunity against severe acute respiratory syndrome coronavirus,2011-06,高福
(11) 2009 Pandemic influenza virus: what special for its HA and NA,2011-01,高福