071004-水生生物学
090801-水产养殖

鱼类病原微生物学
鱼类药理学

1995-09--1998-11   中国科学院水生生物研究所   博士
1985-09--1988-06   江苏农学院   硕士
1981-09--1985-06   江西农业大学   学士

   

2002-06~2004-06,韩国国立健康研究院, 博士后
1999-07~2000-03,丹麦皇家农业与兽医大学, 合作研究
1988-07~现在, 中国科学院水生生物研究所, 研习员，副研，研究员

2021-03-01-2021-07-31,International Expert on Anti-Microbial Resistance, 咨询顾问
2012-06-01-今,农业部兽药评审专家,
2011-06-13-今,欧洲鱼病学家学会会员,
2007-03-11-今,中国兽药典委员会委员,

水产动物病害防控与免疫学

   

（1） 水产养殖精准用药技术研究及推广应用, 二等奖, 专项, 2019
（2） 江苏省主要经济鱼类重要病害防控技术集成与应用, 一等奖, 专项, 2019
（3） 鳗鲡细菌性和病毒性疾病的病原生物学、病理学和防治对策研究, 二等奖, 院级, 1998
（4） 淡水优质育珠蚌疾病的诊断与防治技术研究, 三等奖, 省级, 1996

[1] 李爱华, 刘天强, 彭波, 张倩倩. 一种检测ST251型致病性嗜水气单胞菌的试剂盒及应用. CN: CN105969907A, 2016-09-28.

[2] 李爱华, 李彤彤, 王谢昊. 一种防治水产养殖动物真菌病的中药制剂及制备方法. CN: CN103860663A, 2014-06-18.

[3] 李爱华, 季成, 杨五名, 刘金玉. 过氧乙酸在鱼类养殖中的用途. CN: CN101249086A, 2008-08-27.

[4] 李爱华, 王文博, 蔡桃珍, 吴玉深. 刺五加在水产养殖中的应用. CN: CN1377574A, 2002-11-06.

   

[1] Jicheng Yang, Yaoyao Lin, Zhaohui Wei, Zhenbing Wu, Qianqian Zhang, Jingwen Hao, Shuyi Wang, Aihua Li. Edwardsiella ictaluri Almost Completely Occupies the Gut Microbiota of Fish Suffering from Enteric Septicemia of Catfish (Esc). FISHES[J]. 2023, 8(30): https://doaj.org/article/177538e4358d468c9a579342222c8d50.
[2] Shuyi Wang, Jingwen Hao, Jicheng Yang, Qianqian Zhang, 李爱华. The Attenuation Mechanism and Live Vaccine Potential of a Low-Virulence Edwardsiella ictaluri Strain Obtained by Rifampicin Passaging Culture. Journal of Microbiology and Biotechnology. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2023, [3] Jicheng Yang, Qianqian Zhang, Tanglin Zhang, Shuyi Wang, Jingwen Hao, Zhenbing Wu, Aihua Li, Konstantinos Ar Kormas. Comparative Analysis of the Symbiotic Microbiota in the Chinese Mitten Crab ( Eriocheir sinensis ): Microbial Structure, Co-Occurrence Patterns, and Predictive Functions. MICROORGANISMS. 2023, 11(3): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053967/.
[4] Wu, Zhenbing, Zhang, Qianqian, Yang, Jicheng, Zhang, Jinyong, Fu, Jie, Dang, Chenyuan, Liu, Mansen, Wang, Shuyi, Lin, Yaoyao, Hao, Jingwen, Weng, Meiqi, Xie, Derong, Li, Aihua. Significant alterations of intestinal symbiotic microbiota induced by intraperitoneal vaccination mediate changes in intestinal metabolism of NEW Genetically Improved Farmed Tilapia (NEW GIFT, Oreochromis niloticus). MICROBIOME[J]. 2022, 10(1): http://dx.doi.org/10.1186/s40168-022-01409-6.
[5] Hao, Jingwen, Wang, Shuyi, Wei, Zhaohui, Zhang, Qianqian, Wu, Zhenbing, Lin, Yaoyao, Yang, Jicheng, Zhang, Jinyong, Zhang, Defeng, Li, Aihua. Construction of Streptococcus agalactiae sialic acid mutant and evaluation of its potential as a live attenuated vaccine in Nile tilapia (Oreochromis niloticus). JOURNAL OF APPLIED MICROBIOLOGY[J]. 2022, 133(4): 2403-2416, http://dx.doi.org/10.1111/jam.15706.
[6] Weng, Meiqi, Xie, Derong, Zhang, Qianqian, Li, Aihua, Zhang, Jinyong. First report of Ovipleistophora ovariae and O. diplostomuri in China provides new insights into the intraspecific genetic variation and extends their distribution. PARASITOLOGY[J]. 2022, 149(3): 314-324, http://dx.doi.org/10.1017/S0031182021001852.
[7] Weng, Meiqi, Xie, Derong, Zhang, Qianqian, Li, Aihua, Zhang, Jinyong. Morphological and phylogenetic characterization of a new microsporidium, Triwangia gracilipes n. sp. From the freshwater shrimp Caridina gracilipes (Decapoda: Atyidae) in China. JOURNAL OF INVERTEBRATE PATHOLOGY[J]. 2022, 187: http://dx.doi.org/10.1016/j.jip.2021.107691.
[8] Lin, Yaoyao, Yang, Jicheng, Wu, Zhenbing, Zhang, Qianqian, Wang, Shuyi, Hao, Jingwen, Ouyang, Lijian, Li, Aihua. Establishment of Epidemiological Resistance Cut-Off Values of Aquatic Aeromonas to Eight Antimicrobial Agents. MICROORGANISMS[J]. 2022, 10(4): http://dx.doi.org/10.3390/microorganisms10040776.
[9] Hao Jingwen, Li Aihua, Yang Jicheng, Wu, Zhenbin, Zhang Qianqian, Wang Shuyi, Hao Jingwen, Ouyang Lijian. Attenuated Streptococcus agalactiae WC1535 ∆Sia perturbs the gut microbiota of Oreochromis niloticus, massively colonizes the intestine, and induces intestinal mucosal immunity after intraperitoneal inoculation. Frontiers in Microbiology[J]. 2022, 13: https://pubmed.ncbi.nlm.nih.gov/36439833/.
[10] Sun Hao, Zheng Huina, Liao Baolin, Chen Bogui, 李爱华, Xiao*Baohua. Algiphilus acroporae sp. nov. and Coraliihabitans acroporae gen. nov. sp. nov., isolated from scleractinian coral Acropora digitifera. International Journal of Systematic and Evolutionary MicrobiologyInt. J. Syst. Evol. Microbiol[J]. 2022, [11] Wu, Zhenbing, Zhang, Qianqian, Lin, Yaoyao, Hao, Jingwen, Wang, Shuyi, Zhang, Jingyong, Li, Aihua. Taxonomic and Functional Characteristics of the Gill and Gastrointestinal Microbiota and Its Correlation with Intestinal Metabolites in NEW GIFT Strain of Farmed Adult Nile Tilapia (Oreochromis niloticus). MICROORGANISMS[J]. 2021, 9(3): http://dx.doi.org/10.3390/microorganisms9030617.
[12] Weng, Meiqi, Zhang, Jinyong, Li, Aihua, Zhang, Qianqian, Sato, Hiroshi. Morphological and molecular characterization of a new microsporidium, Janacekia tainanus n. sp. from the adipose tissue of Kiefferulus tainanus (Diptera: Chironomidae) in China. JOURNAL OF INVERTEBRATE PATHOLOGY[J]. 2021, 182: http://dx.doi.org/10.1016/j.jip.2021.107578.
[13] Wu, Zhenbing, Zhang, Qianqian, Zhang, Tanglin, Chen, Jiwang, Wang, Shuyi, Hao, Jingwen, Lin, Yaoyao, Li, Aihua. Association of the microbiota dysbiosis in the hepatopancreas of farmed crayfish ( Procambarus clarkii ) with disease outbreaks. AQUACULTURE[J]. 2021, 536: http://dx.doi.org/10.1016/j.aquaculture.2021.736492.
[14] 刘新华, 翁美其, 宋锐, 赵媛莉, 李爱华, 章晋勇. 三棱碘泡虫（粘体动物门：碘泡科）重描述及其系统发育关系分析. 水产学报[J]. 2021, 45(8): 1340-1349, http://lib.cqvip.com/Qikan/Article/Detail?id=7105811490.
[15] QianQian, Zhang, ShengLong, Jian, KeMao, Li, ZhenBing, Wu, HongTao, Guan, JinWen, Hao, ShuYi, Wang, YaoYao, Lin, GuoJie, Wang, AiHua, Li. Community structure of bacterioplankton and its relationship with environmental factors in the upper reaches of the Heihe River in Qinghai Plateau. ENVIRONMENTAL MICROBIOLOGY[J]. 2021, 23(2): 1210-1221, http://dx.doi.org/10.1111/1462-2920.15358.
[16] Zhang, Qianqian, Lin, Yaoyao, Zhang, Tanglin, Wu, Yafeng, Fang, Ping, Wang, Shuyi, Wu, Zhenbin, Hao, Jingwen, Li, Aihua. Etiological characteristics of "tail blister disease" of Australian redclaw crayfish (Cherax quadricarinatus). JOURNAL OF INVERTEBRATE PATHOLOGY[J]. 2021, 184: http://dx.doi.org/10.1016/j.jip.2021.107643.
[17] 王文博, 刘品, 窦玲玲, 王平, 宁越, 惠瑞敏, 冯亚龙, 李爱华, 张义兵. 中国大鲵研究概况. 水生生物学报[J]. 2021, 45(2): 464-472, http://lib.cqvip.com/Qikan/Article/Detail?id=7104182979.
[18] He, Tian Tian, Zhou, Ying, Liu, Ying Li, Li, Duan You, Nie, Pin, Li, Ai Hua, Xie, Hai Xia. Edwardsiella piscicida type III protein EseJ suppresses apoptosis through down regulating type 1 fimbriae, which stimulate the cleavage of caspase-8. CELLULAR MICROBIOLOGY[J]. 2020, 22(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000540798600006.
[19] Liu, Xinhua, Wen, Meiqi, Zhao, Yuanli, Li, Aihua, Zhang, Jinyong. Morphological and molecular characterization of a new freshwater microsporidium, Jirovecia sinensis sp. n. (Microsporidia) infecting the coelomocytes of Branchiura sowerbyi (Oligochaeta: Naididae) in China. JOURNAL OF INVERTEBRATE PATHOLOGY[J]. 2020, 173: http://dx.doi.org/10.1016/j.jip.2020.107368.
[20] 王文博, 陈鹏, 刘品, 惠瑞敏, 赵琴, 窦玲玲, 王平, 李爱华, 张义兵. 甘草在水产养殖中的应用. 水生生物学报[J]. 2020, 44(1): 231-236, http://lib.cqvip.com/Qikan/Article/Detail?id=7100868170.
[21] Zhao, Yuanli, Liu, Xinhua, Xi, Bingwen, Zhang, Qianqian, Li, Aihua, Zhang, Jinyong. Transcriptomic analysis of oligochaete immune responses to myxosporeans infection: Branchiura sowerbyi infected with Myxobolus cultus. JOURNAL OF INVERTEBRATE PATHOLOGY[J]. 2020, 169: http://dx.doi.org/10.1016/j.jip.2019.107283.
[22] 龙梦, 李彤彤, 江遥, 张倩倩, 张德峰, 张富铁, 王剑伟, 李爱华. 长江上游网箱养殖圆口铜鱼杀鲑气单胞菌杀鲑亚种的分离与鉴定（英文）. 水生生物学报. 2020, 153-161, [[["https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDLAST2020&filename=SSWX202001019&v=MjE1NjFYMUx1eFlTN0RoMVQzcVRyV00xRnJDVVI3cWVadWR1RnlqbVZidk1OajdjZHJHNEhOSE1ybzlFYllSOGU="]]].
[23] Wu, Zhenbing, Wang, Shuyi, Zhang, Qianqian, Hao, Jingwen, Lin, Yaoyao, Zhang, Jinyong, Li, Aihua. Assessing the intestinal bacterial community of farmed Nile tilapia (Oreochromis niloticus) by high-throughput absolute abundance quantification. AQUACULTURE[J]. 2020, 529: http://dx.doi.org/10.1016/j.aquaculture.2020.735688.
[24] YuanYuan Yao, DanDan Chen, ZhengWei Cui, XiangYang Zhang, YuanYuan Zhou, Xia Guo, AiHua Li, YongAn Zhang. Oral vaccination of tilapia against Streptococcus agalactiae using Bacillus subtilis spores expressing Sip. FISH AND SHELLFISH IMMUNOLOGY. 2019, 86: 999-1008, http://dx.doi.org/10.1016/j.fsi.2018.12.060.
[25] Wu, Zhenbing, Gatesoupe, FrancoisJoel, Zhang, Qianqian, Wang, Xiehao, Feng, Yuqing, Wang, Shuyi, Feng, Dongyue, Li, Aihua. High-throughput sequencing reveals the gut and lung prokaryotic community profiles of the Chinese giant salamander (Andrias davidianus). MOLECULAR BIOLOGY REPORTS[J]. 2019, 46(5): 5143-5154, https://www.webofscience.com/wos/woscc/full-record/WOS:000495590600047.
[26] Zhang, Q Q, Li, A H, Liu, L H. Inhibitory Effects of Galla chinensis, Tannic Acid, and Gallic Acid on Saprolegnia parasitica. ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH[J]. 2019, 71: [27] Yuanli Zhao, Xiuhua Liu, Hiroshi Sato, Qianqian Zhang, Aihua Li, Jinyong Zhang. RNA-seq analysis of local tissue of Carassius auratus gibelio with pharyngeal myxobolosis: Insights into the pharyngeal mucosal immune response in a fish-parasite dialogue. FISH AND SHELLFISH IMMUNOLOGY. 2019, 94: 99-112, http://dx.doi.org/10.1016/j.fsi.2019.08.076.
[28] 冯宇晴, 张倩倩, 章晋勇, 张兰梨, 马丽娜, 冯东岳, 吴振兵, 郝静文, 王姝懿, 李爱华. AmoA、AmoE和AmoF蛋白在嗜水气单胞菌铁载体合成中的作用研究. 水生生物学报[J]. 2019, 43(3): 486-493, http://lib.cqvip.com/Qikan/Article/Detail?id=7001985801.
[29] Zhang, Qianqian, Wang, Xiehao, Zhang, Defeng, Long, Meng, Wu, Zhenbing, Feng, Yuqing, Hao, Jingwen, Wang, Shuyi, Liao, Qian, Li, Aihua. De novo Assembly and Analysis of Amur Sturgeon (Acipenser schrenckii) Transcriptome in Response to Mycobacterium Marinum Infection to Identify Putative Genes Involved in Immunity. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2019, 29(8): 1324-1334, http://dx.doi.org/10.4014/jmb.1903.03034.
[30] Zhao, Yuanli, Liu, Xiuhua, Sato, Hiroshi, Zhang, Qianqian, Li, Aihua, Zhang, Jinyong. RNA-seq analysis of local tissue of Carassius auratus gibelio with pharyngeal myxobolosis: Insights into the pharyngeal mucosal immune response in a fish-parasite dialogue. FISH & SHELLFISH IMMUNOLOGY[J]. 2019, 94: 99-112, http://dx.doi.org/10.1016/j.fsi.2019.08.076.
[31] 李爱华. Significant improvement of intestinal microbiota of gibel carp (Carassius auratus gibelio) after traditional Chinese medicine feeding.. J Appl Microbiol.. 2018, [32] 张兰梨, 李爱华, 冯宇晴, 吴振兵, 王谢昊, 陈辉, 张倩倩. 嗜水气单胞菌cpxRA缺失株构建及生物学特性研究. 水生生物学报[J]. 2018, 42(1): 1-10, http://lib.cqvip.com/Qikan/Article/Detail?id=674304632.
[33] 李爱华, 黄锦炉, 钱雪桥, 谭晓晨, 王正凯. 允饲植物源复方制剂对草鱼（Ctenopharyngodon idellus）的免疫增强作用研究. 海洋与湖沼[J]. 2017, 48(3): 576-582, [34] 叶嵘, 李文华, 温周瑞, 陈霞, 卢伶俐, 李丹, 李爱华, 李彤彤. 荧光定量PCR检测野芷湖水体气单胞菌数量周年动态. 养殖与饲料[J]. 2017, 8-12, http://lib.cqvip.com/Qikan/Article/Detail?id=7000328173.
[35] 谭晓晨, 黄锦炉, 李爱华, 钱雪桥, 王正凯. 允饲植物源复方制剂对草鱼（Ctenopharyngodon idellus）组织形态和生长性能的作用研究. 海洋与湖沼[J]. 2017, 48(4): 814-821, [36] 赵德明, 李爱华, 杨利峰, 赵颖, 王剑伟. 稀有鮈鲫的组织学切片制作和苏木精-伊红染色. 实验动物科学[J]. 2017, 31-34, http://ir.ihb.ac.cn/handle/342005/39005.
[37] 李爱华. 76. Tongtong Li, Meng Long, Huan Li, François-Joël Gatesoupe, Xujie Zhang, Qianqian Zhang, Dongyue Feng*,Aihua Li*. Multi-omics analysis reveals a correlation between the host phylogeny, gut microbiota and metabolite profiles in cyprinid fishes.. Frontiers in Microbiology. 2017, [38] Li, Tongtong, Long, Meng, Li, Huan, Gatesoupe, FrancoisJoel, Zhang, Xujie, Zhang, Qianqian, Feng, Dongyue, Li, Aihua. Multi-Omics Analysis Reveals a Correlation between the Host Phylogeny, Gut Microbiota and Metabolite Profiles in Cyprinid Fishes. FRONTIERS IN MICROBIOLOGY[J]. 2017, 8(1): http://dx.doi.org/10.3389/fmicb.2017.00454.
[39] Li, Tongtong, Long, Meng, Ji, Cheng, Shen, Zhixin, Gatesoupe, FrancoisJoel, Zhang, Xujie, Zhang, Qianqian, Zhang, Lanli, Zhao, Yuanli, Liu, Xinhua, Li, Aihua. Alterations of the gut microbiome of largemouth bronze gudgeon (Coreius guichenoti) suffering from furunculosis. SCIENTIFIC REPORTS[J]. 2016, 6(1): http://ir.ihb.ac.cn/handle/342005/34603, http://www.irgrid.ac.cn/handle/1471x/6853844, http://ir.ihb.ac.cn/handle/342005/34604, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000380981300001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[40] 宣引明, 蒋明, 张元柱, 李爱华, 陈文怡, 张茂友, 顾建华, 姜光明. 甲鱼养殖系统霍乱弧菌的调查研究. 中国预防医学杂志[J]. 2016, 17(1): 50-54, [41] Long, Meng, Nielsen, Tue K, Leisner, Jorgen J, Hansen, Lars H, Shen, Zhi X, Zhang, Qian Q, Li, Aihua. Aeromonas salmonicida subsp salmonicida strains isolated from Chinese freshwater fish contain a novel genomic island and possible regional-specific mobile genetic elements profiles. FEMS MICROBIOLOGY LETTERS[J]. 2016, 363(17): http://dx.doi.org/10.1093/femsle/fnw190.
[42] Liu, XinHua, Batueva, MarinaD, Zhao, YuanLi, Zhang, JinYong, Zhang, QianQian, Li, TongTong, Li, AiHua. Morphological and molecular characterisation of Myxobolus pronini n. sp (Myxozoa: Myxobolidae) from the abdominal cavity and visceral serous membranes of the gibel carp Carassius auratus gibelio (Bloch) in Russia and China. PARASITES & VECTORS[J]. 2016, 9(1): https://doaj.org/article/f1ceda21abaf4a798a0c3c3bac7bded9.
[43] Ji, Yachan, Li, Jinquan, Qin, Zhendong, Li, Aihua, Gu, Zemao, Liu, Xiaoling, Lin, Li, Zhou, Yang. Contribution of nuclease to the pathogenesis of Aeromonas hydrophila. VIRULENCE[J]. 2015, 6(5): 515-522, http://www.irgrid.ac.cn/handle/1471x/978700.
[44] 张倩倩, 刘天强, 李彤彤, 徐静, 龙梦, 王谢昊, 龚小宁, 李爱华. 玉屏风散对鱼类非特异性免疫和免疫相关基因表达的影响. 水生生物学报[J]. 2015, 39(6): 1076-1084, http://lib.cqvip.com/Qikan/Article/Detail?id=666804649.
[45] Long, Meng, Zhao, Juan, Li, Tongtong, Tafalla, Carolina, Zhang, Qianqian, Wang, Xiehao, Gong, Xiaoning, Shen, Zhixin, Li, Aihua. Transcriptomic and proteomic analyses of splenic immune mechanisms of rainbow trout (Oncorhynchus mykiss) infected by Aeromonas salmonicida subsp salmonicida. JOURNAL OF PROTEOMICS[J]. 2015, 122: 41-54, http://dx.doi.org/10.1016/j.jprot.2015.03.031.
[46] Zhang, XuJie, Yang, WuMing, Zhang, DeFeng, Li, TongTong, Gong, XiaoNing, Li, AiHua. Does the gastrointestinal tract serve as the infectious route of Aeromonas hydrophila in crucian carp (Carassius carassius)?. AQUACULTURE RESEARCH[J]. 2015, 46(1): 141-154, http://dx.doi.org/10.1111/are.12168.
[47] 刘衍鹏, 黄冠军, 刘天强, 李爱华, 肖丹. 弧菌属PCR检测方法的建立与应用. 淡水渔业[J]. 2015, 45(3): 88-92, http://lib.cqvip.com/Qikan/Article/Detail?id=664892365.
[48] Li, Tongtong, Long, Meng, Gatesoupe, FrancoisJoel, Zhang, Qianqian, Li, Aihua, Gong, Xiaoning. Comparative Analysis of the Intestinal Bacterial Communities in Different Species of Carp by Pyrosequencing. MICROBIAL ECOLOGY[J]. 2015, 69(1): 25-36, http://www.irgrid.ac.cn/handle/1471x/978731.
[49] Wu, Nan, Zhang, XiangYang, Huang, Bei, Zhang, Nu, Zhang, XuJie, Guo, Xia, Chen, XiaoLing, Zhang, Yu, Wu, Han, Li, Shun, Li, AiHua, Zhang, YongAn. Investigating the potential immune role of fish NCAMs: Molecular cloning and expression analysis in mandarin fish. FISH & SHELLFISH IMMUNOLOGY[J]. 2015, 46(2): 765-777, http://dx.doi.org/10.1016/j.fsi.2015.08.006.
[50] Zhang, De Feng, Ji, Cheng, Zhang, Xu Jie, Li, Tong Tong, Li, Ai Hua, Gong, Xiao Ning. Mixed mycobacterial infections in farmed sturgeons. AQUACULTURE RESEARCH[J]. 2015, 46(8): 1914-1923, http://www.irgrid.ac.cn/handle/1471x/978699.
[51] Hu, BaoQing, Liu, Yi, Wen, ChunGen, Li, AiHua, Hu, XiangPing, Wu, Dan, Hu, XiaoJuan, Tao, ZhiYing. Cloning and expression of selenoprotein W from pearl mussels Cristaria plicata. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY[J]. 2014, 167: 8-15, http://dx.doi.org/10.1016/j.cbpb.2013.09.008.
[52] Zhang, Xujie, Yang, Wuming, Wu, Han, Gong, Xiaoning, Li, Aihua. Multilocus sequence typing revealed a clonal lineage of Aeromonas hydrophila caused motile Aeromonas septicemia outbreaks in pond-cultured cyprinid fish in an epidemic area in central China. AQUACULTURE[J]. 2014, 432: 1-6, http://dx.doi.org/10.1016/j.aquaculture.2014.04.017.
[53] 张德锋, 李爱华, 龚小宁. 鲟分枝杆菌病及其病原研究. 水生生物学报[J]. 2014, 38(3): 495-504, http://lib.cqvip.com/Qikan/Article/Detail?id=49841414.
[54] Zhang, D F, Zhang, Q Q, Li, A H. Development of a multiplex PCR assay for rapid and simultaneous detection of four genera of fish pathogenic bacteria. LETTERS IN APPLIED MICROBIOLOGY[J]. 2014, 59(5): 471-478, http://www.irgrid.ac.cn/handle/1471x/929330.
[55] Hu, Xiaojuan, Hu, Xiangping, Hu, Baoqing, Wen, Chungen, Xie, Yanhai, Wu, Dan, Tao, Zhiying, Li, Aihua, Gao, Qian. Molecular cloning and characterization of cathepsin L from freshwater mussel, Cristaria plicata. FISH & SHELLFISH IMMUNOLOGY[J]. 2014, 40(2): 446-454, http://dx.doi.org/10.1016/j.fsi.2014.07.005.
[56] 李爱华. Multilocus sequence typing revealed a clonal lineage of Aeromonas hydrophila caused motile Aeromonas septicaemia outbreaks in pond cultured cyprinid fish in an epidemic area, central China. AQUACULTURE. 2014, [57] Zhang, Defeng, Li, Aihua, Guo, Yujuan, Zhang, Qianqian, Chen, Xuenian, Gong, Xiaoning. Molecular characterization of Streptococcus agalactiae in diseased farmed tilapia in China. AQUACULTURE[J]. 2013, 412: 64-69, http://dx.doi.org/10.1016/j.aquaculture.2013.07.014.
[58] Zhao, Li Juan, Lu, Jin Fang, Nie, P, Li, Ai Hua, Xiong, Bang Xi, Xie, Hai Xia. Roles of plasmid-encoded proteins, EseH, EseI and EscD in invasion, replication and virulence of Edwardsiella ictaluri. VETERINARY MICROBIOLOGY[J]. 2013, 166(1-2): 233-241, http://dx.doi.org/10.1016/j.vetmic.2013.05.023.
[59] 张旭杰, 杨五名, 李彤彤, 李爱华. 湖北地区暴发病池塘中嗜水气单胞菌的遗传多样性和毒力特征研究. 水生生物学报[J]. 2013, 37(3): 458-466, http://lib.cqvip.com/Qikan/Article/Detail?id=46240228.
[60] 李爱华. Effect of berberine hydrochloride on grass carp Ctenopharyngodon idella serum actericidal activity against Edwardsiella ictaluri. Fish and Shellfish Immunology. 2012, [61] Liu, J Y, Li, A H. First case of Aeromonas schubertii infection in the freshwater cultured snakehead fish, Ophiocephalus argus (Cantor), in China. JOURNAL OF FISH DISEASES[J]. 2012, 35(5): 335-342, http://www.irgrid.ac.cn/handle/1471x/495361.
[62] Ji, Cheng, Zhang, De Feng, Li, Ai Hua, Gong, Xiao Ning. Effect of berberine hydrochloride on grass carp Ctenopharyngodon idella serum bactericidal activity against Edwardsiella ictaluri. FISH & SHELLFISH IMMUNOLOGY[J]. 2012, 33(1): 143-145, http://dx.doi.org/10.1016/j.fsi.2012.03.022.
[63] 郭玉娟, 张德锋, 樊海平, 陈学年, 李彤彤, 李爱华. 中国南方地区罗非鱼无乳链球菌的分子流行病学研究. 水产学报[J]. 2012, 36(3): 399-406, http://lib.cqvip.com/Qikan/Article/Detail?id=41242058.
[64] Ji, C, Li, A H, Xie, J, Zhang, D F, Liu, J Y. Bactericidal activity of grass carp Ctenopharyngodon idella C9-deficient serum against Aeromonas hydrophila. JOURNAL OF FISH BIOLOGY[J]. 2011, 79(7): 2083-2086, http://www.irgrid.ac.cn/handle/1471x/495362.
[65] Li, AiHua, Na, ByoungKuk, Song, KyoungJu, Lim, SungBin, Chong, ChomKyu, Park, YunKyu, Kim, TongSoo. IDENTIFICATION AND CHARACTERIZATION OF A MITOCHONDRIAL MANGANESE SUPEROXIDE DISMUTASE OF SPIROMETRA ERINACEI. JOURNAL OF PARASITOLOGY[J]. 2011, 97(6): 1106-1112, https://www.webofscience.com/wos/woscc/full-record/WOS:000299022100023.
[66] Gu, Zemao, Wang, Jianguo, Ke, Xiaoli, Liu, Yang, Liu, Xiaoling, Gong, Xiongning, Li, Aihua. Phylogenetic position of the freshwater fish trypanosome, Trypanosoma ophiocephali (Kinetoplastida) inferred from the complete small subunit ribosomal RNA gene sequence. PARASITOLOGY RESEARCH[J]. 2010, 106(5): 1039-1042, http://ir.ihb.ac.cn/handle/342005/13641.
[67] Li, AiHua, Na, ByoungKuk, Ahn, SungKyu, Cho, ShinHyeong, Pak, JhangHo, Park, YunKyu, Kim, TongSoo. Functional expression and characterization of a cytosolic copper/zinc-superoxide dismutase of Spirometra erinacei. PARASITOLOGY RESEARCH[J]. 2010, 106(3): 627-635, http://ir.ihb.ac.cn/handle/342005/13649.
[68] Zhang, Defeng, Li, Aihua, Xie, Jun, Ji, Cheng. In vitro antibacterial effect of berberine hydrochloride and enrofloxacin to fish pathogenic bacteria. AQUACULTURE RESEARCH[J]. 2010, 41(7): 1095-1100, http://ir.ihb.ac.cn/handle/342005/13609.
[69] 李爱华. 新渔药报批中的临床试验之我见. 渔业致富指南[J]. 2010, 15-17, http://lib.cqvip.com/Qikan/Article/Detail?id=34159492.
[70] Liu, Jin Yu, Li, Ai Hua, Zhou, Dong Ren, Wen, Zhou Rui, Ye, Xue Ping. Isolation and characterization of Edwardsiella ictaluri strains as pathogens from diseased yellow catfish Pelteobagrus fulvidraco (Richardson) cultured in China. AQUACULTURE RESEARCH[J]. 2010, 41(12): 1835-1844, https://www.webofscience.com/wos/woscc/full-record/WOS:000283946200012.
[71] Yang, Wuming, Li, Aihua. Isolation and characterization of Streptococcus dysgalactiae from diseased Acipenser schrenckii. AQUACULTURE[J]. 2009, 294(1-2): 14-17, http://dx.doi.org/10.1016/j.aquaculture.2009.05.018.
[72] 张德锋, 李爱华. 斑马鱼分枝杆菌病的研究概况. 实验动物科学[J]. 2009, 64-67, http://lib.cqvip.com/Qikan/Article/Detail?id=32949493.
[73] Liu, Jin Yu, Li, Ai Hua, Ji, Cheng, Yang, Wu Ming. First description of a novel Weissella species as an opportunistic pathogen for rainbow trout Oncorhynchus mykiss (Walbaum) in China. VETERINARY MICROBIOLOGY[J]. 2009, 136(3-4): 314-320, http://dx.doi.org/10.1016/j.vetmic.2008.11.027.
[74] Li, Ming, Wang, Chong, Wang, Jianguo, Li, Aihua, Gong, Xiaoning, Ma, Hongwei. Redescription of Balantidium polyvacuolum Li 1963 (Class: Litostomatea) inhabiting the intestines of Xenocyprinae fishes in Hubei, China. PARASITOLOGY RESEARCH[J]. 2009, 106(1): 177-182, http://ir.ihb.ac.cn/handle/152342/7470.
[75] 刘金玉, 杨五名, 李爱华, 何广文. 斑点叉尾鮰套肠症的病原学初步研究. 水生生物学报[J]. 2008, http://lib.cqvip.com/Qikan/Article/Detail?id=1000601756.
[76] 李爱华. 池塘中的氧气循环及翻塘的发生机理. 渔业致富指南[J]. 2008, 24-25, http://lib.cqvip.com/Qikan/Article/Detail?id=27583279.
[77] 汪建国, 王桂堂, 卢全章, 李爱华, 张奇亚. 鱼病防治. 2008, http://ir.ihb.ac.cn/handle/342005/10576.
[78] 杨五名, 李爱华, 刘金玉, 唐辉远. 广东中山地区气单胞菌环境株的分离、鉴定及系统发育关系. 2006中国微生物学会第九次全国会员代表大会暨学术年会论文摘要集null. 2007, http://ir.ihb.ac.cn/handle/342005/14780.
[79] 李爱华, 何广文. 斑点叉尾鲴几种疑难疾病的介绍. 渔业致富指南[J]. 2007, 39-40, http://lib.cqvip.com/Qikan/Article/Detail?id=23994979.
[80] 李爱华. 斑点叉尾鮰几种疑难疾病的介绍. 中国水产[J]. 2007, 59-60, http://lib.cqvip.com/Qikan/Article/Detail?id=23961950.
[81] 李爱华, 何广文. 斑点叉尾鮰几种疑难疾病的介绍. 渔业致富指南[J]. 2007, 42-43, http://lib.cqvip.com/Qikan/Article/Detail?id=24144836.
[82] Zhu, Daling, Li, Aihua, Wang, Jianguo, Li, Ming, Cai, Taozhen. Cloning, expression and characterization of aerolysin from Aeromonas hydrophila in Escherichia coli. INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS[J]. 2007, 44(4): 204-208, http://ir.ihb.ac.cn/handle/152342/8398.
[83] 杨五名, 李爱华, 刘金玉, 唐辉远. 广东中山地区气单胞菌环境株的分离、鉴定及系统发生关系. 微生物学通报[J]. 2007, 34(4): 745-748, http://lib.cqvip.com/Qikan/Article/Detail?id=25180494.
[84] 李爱华, Tong Soo Kim. 猪囊尾蚴铜/锌超氧化物歧化酶（Cu/ZnSOD）基因的克隆和表达. 中国人兽共患病学报[J]. 2006, 22(12): 1124-1128, http://ir.ihb.ac.cn/handle/152342/1192.
[85] Li, Aihua, Yang, Wuming, Hu, Jin, Wang, Wenbo, Cai, Taozhen, Wang, Jianguo. Optimization by orthogonal array design and humoral immunity of the bivalent vaccine against Aeromonas hydrophila and Vibrio fluvialis infection in crucian carp (Carassius auratus L.). AQUACULTURE RESEARCH[J]. 2006, 37(8): 813-820, http://ir.ihb.ac.cn/handle/152342/8976.
[86] 胡靖, 李爱华, 胡成钰, 朱大玲, 蔡桃珍, 汪建国, 司亚东. 温度和pH值对嗜水气单胞菌毒力基因表达的影响. 南京理工大学学报：自然科学版[J]. 2006, 30(3): 375-380, http://lib.cqvip.com/Qikan/Article/Detail?id=22246615.
[87] Wang, WenBo, Wang, YaPing, Hu, Wei, Li, AiHua, Cai, TaoZhen, Zhu, ZuoYan, Wang, JianGuo. Effects of the "all-fish" growth hormone transgene expression on non-specific immune functions of common carp, Cyprinus carpio L.. AQUACULTURE[J]. 2006, 259(1-4): 81-87, http://dx.doi.org/10.1016/j.aquaculture.2006.05.016.
[88] 王文博, 汪建国, 李爱华, 林小涛. 中草药应用于水产养殖的研究概况. 中国水产[J]. 2006, 60-61, http://ir.ihb.ac.cn/handle/152342/1188.
[89] 朱大玲, 李爱华, 汪建国, 李明, 蔡桃珍, 胡靖. 嗜水气单胞菌毒力与毒力基因分布的相关性. 中山大学学报：自然科学版[J]. 2006, 45(1): 82-85, http://lib.cqvip.com/Qikan/Article/Detail?id=21207126.
[90] 王文博, 汪亚平, 胡炜, 李爱华, 蔡桃珍, 朱作言, 汪建国. 转生长激素基因鲤鱼几项血液指标的检测. 高技术通讯[J]. 2005, 15(10): 89-93, http://lib.cqvip.com/Qikan/Article/Detail?id=20324231.
[91] Wang Wen-bo, Wang Jian-guo (wangjg@ihb.ac.cn), Li Ai-hua, Cai Tao-zhen. Changes of cortisol and lysozyme levels in Carassius auratus blood after handling stress. ACTA HYDROBIOLOGICA SINICA[J]. 2004, 28(6): 682-684, http://www.irgrid.ac.cn/handle/1471x/543337.
[92] 王文博, 汪建国, 李爱华, 蔡桃珍. 振荡胁迫后鲫血液皮质醇和溶菌酶水平的变化. 水生生物学报[J]. 2004, 28(6): 682-684, http://lib.cqvip.com/Qikan/Article/Detail?id=10939181.
[93] 王文博, 汪建国, 李爱华, 蔡桃珍. 拥挤胁迫后鲫鱼血液皮质醇和溶菌酶水平的变化及对病原的敏感性. 中国水产科学[J]. 2004, 11(5): 408-412, http://lib.cqvip.com/Qikan/Article/Detail?id=10687873.
[94] 朱大玲, 李爱华, 钱冬, 汪建国. 嗜水气单胞菌毒力基因的研究进展. 水生生物学报[J]. 2004, 28(1): 80-84, http://lib.cqvip.com/Qikan/Article/Detail?id=9017559.
[95] 王文博, 李爱华, 汪建国, 蔡桃珍, 吴玉深. 拥挤胁迫对草鱼非特异性免疫功能的影响. 水产学报[J]. 2004, 28(2): 139-144, http://lib.cqvip.com/Qikan/Article/Detail?id=9638488.
[96] 王文博, 李爱华. 环境胁迫对鱼类免疫系统影响的研究概况. 水产学报[J]. 2002, 26(4): 368-374, http://lib.cqvip.com/Qikan/Article/Detail?id=7175332.
[97] 李爱华, 吴玉深, 蔡桃珍, 卢全章. 嗜水气单胞菌和河弧菌二联疫苗对鲫的免疫效果. 水生生物学报[J]. 2002, 26(1): 52-56, http://lib.cqvip.com/Qikan/Article/Detail?id=5867838.
[98] 李爱华. 水产养殖中使用的抗菌药物及细菌耐药性. 中国水产科学[J]. 2002, 9(1): 87-91, http://lib.cqvip.com/Qikan/Article/Detail?id=6103450.
[99] 李爱华, 王文博. 一种中药对鲫鱼免疫功能的促进作用. 鱼类病害研究[J]. 2001, 23(3): 84-84, http://lib.cqvip.com/Qikan/Article/Detail?id=6053187.
[100] 李爱华, 蔡桃珍, 吴玉深, 王伟俊. 我国鱼类病原——嗜水气单胞的耐药性研究. 微生物学通报[J]. 2001, 28(1): 58-, http://lib.cqvip.com/Qikan/Article/Detail?id=5015246.
[101] 王文博, 李爱华. 环境胁迫对鱼类免疫系统影响的研究概况（综述）. 鱼类病害研究[J]. 2001, 23(3): 82-84, http://lib.cqvip.com/Qikan/Article/Detail?id=6053185.
[102] 李爱华. 气单胞菌（Aeromonads）分类与命名的最新进展1. 鱼类病害研究[J]. 2001, 23(2): 25-32, http://lib.cqvip.com/Qikan/Article/Detail?id=5288020.
[103] 李爱华, 蔡桃珍, 吴玉深. 半咸水、海水对几种渔用抗菌药物药效的影响. 鱼类病害研究[J]. 2000, 22(1): 67-71, http://lib.cqvip.com/Qikan/Article/Detail?id=11651376.
[104] 李爱华, 吴玉深, 蔡桃珍, 卢全章. 嗜水气单胞菌和河弧菌二联疫苗对鲫鱼的免疫效果. 鱼类病害研究[J]. 2000, 22(4): 14-20, http://lib.cqvip.com/Qikan/Article/Detail?id=11651386.
[105] 李爱华, 蔡桃珍, 吴玉深. 半咸水，海水对几种渔用抗菌药物体外活性的影响. 水产学报[J]. 2000, 24(6): 544-548, http://lib.cqvip.com/Qikan/Article/Detail?id=4733622.
[106] 李爱华, 聂品, 卢全章. 花鲈水霉病及其病原的初步研究. 水生生物学报[J]. 1999, 23(4): 388-, http://lib.cqvip.com/Qikan/Article/Detail?id=4023192.
[107] 李爱华. 中国鱼类病原菌耐药质粒. 中国兽医学报[J]. 1999, 19(5): 511-, http://lib.cqvip.com/Qikan/Article/Detail?id=7396125.
[108] 李爱华. 氯霉素在草鱼和复合四倍体异育鲫体内的比较药代动力学. 中国兽医学报[J]. 1998, 18(4): 372-374, http://lib.cqvip.com/Qikan/Article/Detail?id=3137354.
[109] 李爱华. 氯霉素在草鱼和复合四倍体异育银鲫体内的比较药代动力学. 中国兽医学报[J]. 1998, 18(4): 372-, http://ir.ihb.ac.cn/handle/152342/4072.
[110] 李爱华, 王伟俊. 鱼类病原菌耐药质粒的研究概况. 中国兽医学报[J]. 1998, 18(3): 309-, http://lib.cqvip.com/Qikan/Article/Detail?id=2990362.
[111] 李爱华. 鱼类病原菌中R^＋质粒的检出及其特性. 水生生物学报[J]. 1998, 22(4): 319-, http://lib.cqvip.com/Qikan/Article/Detail?id=3305039.
[112] 李爱华. 拥挤胁迫对草鱼血浆皮质醇，血糖及肝脏中抗坏血酸含量的影响. 水生生物学报[J]. 1997, 21(4): 384-, http://lib.cqvip.com/Qikan/Article/Detail?id=2762920.
[113] 李爱华, 朱心玲, 韩光祖, 王绪娥, 宫向红. 对虾病害发生的原因调查及对策分析. 海洋渔业[J]. 1996, 18(1): 4-8, http://lib.cqvip.com/Qikan/Article/Detail?id=2372573.
[114] 李爱华. 养殖鱼类疾病的药物防治. 鱼类病害研究[J]. 1996, 18(1): 4-24, http://lib.cqvip.com/Qikan/Article/Detail?id=2403081.
[115] 李爱华, 朱模忠, 解庆宾. 氯霉素在健康、沙门氏菌病和肝损害小型猪体内的药代动力学研究. 扬州大学学报(农业与生命科学版)[J]. 1990, http://ir.ihb.ac.cn/handle/152342/5716.
[116] Yuanli Zhao, Xiuhua Liu, Hiroshi Sato, Qianqian Zhang, Aihua Li, Jinyong Zhang. RNA-seq analysis of local tissue of Carassius auratus gibelio with pharyngeal myxosporidiosis: Insights into the pharyngeal mucosal immune response in a fish-parasite dialogue. FISH AND SHELLFISH IMMUNOLOGY. http://dx.doi.org/10.1016/j.fsi.2019.08.076.

（1） 养殖鱼类疾病防治技术, no, 中原农民出版社, 1998-07, 第 2 作者
（2） 中山生物物种资源, no, 科学出版社, 2007-07, 第 5 作者
（3） 渔药药剂学, no, 农业出版社, 2008-07, 第 3 作者
（4） 渔药制剂工艺学, no, 农业出版社, 2008-07, 第 3 作者
（5） 水产养殖用药速查与使用手册, no, 化学工业出版社, 2009-07, 第 2 作者
（6） 中华人民共和国兽药典兽药使用指南（化学药品卷）, no, 中国农业出版社, 2010-01, 第 5 作者
（7） 中华人民共和国兽药典（第一部）（2010年版）, no, 中国农业出版社, 2011-04, 第 5 作者
（8） 鱼类药理学, Fish Pharmacology, 农业出版社, 2011-12, 第 3 作者
（9） 鱼病学, 农业出版社, 2013-06, 第 5 作者
（10） 2011年、2012年和2013年全国职业兽医资格考试应试指南(水生动物类) , no, 中国农业出版社, 2013-06, 第 5 作者
（11） 中华人民共和国兽药典（第一部）（2020年版）, 中国农业出版社, 2020-12, 第 其他 作者

   

（ 1 ） 养殖鱼类气单胞菌感染的病源追踪研究, 主持, 国家级, 2011-01--2013-12
（ 2 ） 池塘养殖水体中气单胞菌的种群结构及流行病学, 主持, 国家级, 2009-01--2013-12
（ 3 ） 鱼类健康养殖的关键技术研究, 主持, 国家级, 2011-01--2015-12
（ 4 ） 水产用抗生素替代品的创制与产业化应用, 主持, 部委级, 2016-01--2018-12
（ 5 ） 三峡库区水生生物多样性调查及图鉴编撰, 主持, 国家级, 2016-01--2018-12
（ 6 ） 淡水鱼重大传染性疾病免疫预防关键技术研发, 主持, 省级, 2018-06--2019-12
（ 7 ） 中华绒螯蟹肝胰腺病变综合征细菌性病原的影响研究, 主持, 省级, 2018-01--2020-12
（ 8 ） 草鱼肠道菌群与嗜水气单胞菌疫苗的互作及机制研究, 主持, 国家级, 2021-01--2024-12
（ 9 ） “Regional Training on Anti-Microbial Resistance (AMR) Surveillance and Monitoring in Aquaculture” (AMR surveillance training), 主持, 研究所（学校）, 2021-03--2021-12
（ 10 ） 渔农综合种养与综合利用模式示范, 参与, 国家级, 2020-10--2022-12

（1）The implementation of national action plans and experiences to mitigate AMR in Aquaculture： AMR and AMU experience from China   2021-05-04
（2）1. Review of AMR in aquaculture work in China；2. China: Development of National Action Plans on AMR: Aquaculture Component, Project Accomplishments and Impacts   2017-12-12
（3）1. Country progress report on the national planning and the consultations on the development of the aquaculture component of country NAPs on AMR in China 2. Critical review of alternatives to antimicrobials pertaining to diseases affecting carps    2017-08-07
（4）Aquaculture health, AMU and AMR and status of AMR National Action Plans in China    2017-04-10

已指导学生

张旭杰  硕士研究生  071004-水生生物学  

张德锋  博士研究生  071004-水生生物学  

张倩倩  硕士研究生  071004-水生生物学  

李彤彤  博士研究生  071004-水生生物学  

龙梦  博士研究生  071004-水生生物学  

张兰梨  硕士研究生  071004-水生生物学  

冯宇晴  硕士研究生  090801-水产养殖  

贺甜甜  博士研究生  071004-水生生物学  

刘新华  博士研究生  071004-水生生物学  

药园园  博士研究生  071004-水生生物学  

赵媛莉  博士研究生  071004-水生生物学  

现指导学生

吴振兵  博士研究生  071004-水生生物学  

林瑶瑶  硕士研究生  071004-水生生物学  

郝静文  博士研究生  071004-水生生物学  

王姝懿  博士研究生  071004-水生生物学  

翁美其  博士研究生  071007-遗传学