071010-生物化学与分子生物学

蓝细菌分子生物学，蓝细菌代谢工程

2005-09--2011-05   中国科学院水生生物研究所   博士

   

2014-01~现在, 中国科学院青岛生物能源与过程研究所, 副研究员
2011-06~2013-12,中国科学院青岛生物能源与过程研究所, 助理研究员

微生物代谢工程研究现状及展望
微生物代谢工程

   

[1] 吕雪峰, 齐凤霞, 栾国栋, 朱涛, 郭勍. 耐热型环丙烷脂肪酸合成酶NK1-22 ORF3135 及其应用. 202310243123.7, 2023-03-14.

[2] 吕雪峰, 齐凤霞, 栾国栋, 朱涛, 郭勍. 耐热型环丙烷脂肪酸合成酶NK1-22 ORF1256 及其应用. 202310243099.7, 2023-03-14.

[3] 吕雪峰, 朱涛, 赵杨, 李晓, 李胜军, 徐启玉, 赵瑞丰. 一种适用于高盐环境的活体节旋藻藻肥及其制备方法. 202310229713.4, 2023-03-10.

[4] 吕雪峰, 齐凤霞, 朱涛, 栾国栋. 一种念珠藻及其培养方法和应用. 202211053967.7, 2022-08-30.

[5] 吕雪峰, 齐凤霞, 朱涛, 栾国栋, 韩晓娟. 一种波斯枝藻及其培养方法和应用. 202211045959.8, 2022-08-30.

[6] 吕雪峰, 朱涛, 尼丁·克什李, 李辉, 谢玉曼, 齐凤霞. 一种高温耐受型高产碳水化合物的热泉蓝细菌及其应用. CN: CN111996135B, 2022-04-08.

[7] 吕雪峰, 朱涛, 尼丁·克什李, 李辉, 谢玉曼, 齐凤霞. 一种高产碳水化合物的纤细鞘丝藻及其应用. CN: CN111876350B, 2022-04-05.

[8] 吕雪峰, 朱涛, 莫慧琳. 一种蓝细菌脂肪烃合成关键基因及其应用. CN: CN105586351A, 2016-05-18.

[9] 吕雪峰, 解晓慢, 朱涛. 一种高效合成乙烯的构建体及其构建方法和应用. CN: CN104651388A, 2015-05-27.

   

[1] Marcus Ziemann, Viktoria Reimann, Yajing Liang, Yue Shi, Honglei Ma, Yuman Xie, Hui Li, Tao Zhu, Xuefeng Lu, Wolfgang R Hess. CvkR is a MerR-type transcriptional repressor of class 2 type V-K CRISPR-associated transposase systems. NATURE COMMUNICATIONS[J]. 2023, 14(1): 1-16, https://doaj.org/article/8597825b70554120938a5111b0c1739c.
[2] Nitin Keshari, Yang Zhao, Sudipta Kumar Das, Tao Zhu, 吕雪峰. Cyanobacterial community structure and isolates from representative hot springs of Yunnan Province, China using integrative approach. Frontiers in Microbiology[J]. 2022, 13: 872598-, https://www.frontiersin.org/articles/10.3389/fmicb.2022.872598/full.
[3] Brito, Angela, Vieira, Jorge, Vieira, Cristina P, Zhu, Tao, Leao, Pedro N, Ramos, Vitor, Lu, Xuefeng, Vasconcelos, Vitor M, Gugger, Muriel, Tamagnini, Paula. Comparative Genomics Discloses the Uniqueness and the Biosynthetic Potential of the Marine CyanobacteriumHyella patelloides. FRONTIERS IN MICROBIOLOGY[J]. 2020, 11: https://doaj.org/article/a5f03778b39d4222a2858314091a4b39.
[4] Brito, Angela, Vieira, Jorge, Vieira, Cristina P, Zhu, Tao, Leao, Pedro, Ramos, Vitor, Martins, Teresa, Lu, Xuefeng, Vasconcelos, Vitor M, Gugger, Muriel, Tamagnini, Paula. Hyella patelloides, a Marine Cyanobacterium with a Unique Biosynthetic Potential. MARINE DRUGSnull. 2020, 18(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000513184600242.
[5] Reimann, Viktoria, Ziemann, Marcus, Li, Hui, Zhu, Tao, Behler, Juliane, Lu, Xuefeng, Hess, Wolfgang R. Specificities and functional coordination between the two Cas6 maturation endonucleases in Anabaena sp. PCC 7120 assign orphan CRISPR arrays to three groups. RNA BIOLOGY[J]. 2020, 17(10): 1442-1453, https://www.webofscience.com/wos/woscc/full-record/WOS:000544820500001.
[6] Keshari, Nitin, Gugger, Muriel, Zhu, Tao, Lu, Xuefeng. Compatible solutes profiling and carbohydrate feedstock from diversified cyanobacteria. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS[J]. 2019, 43: http://dx.doi.org/10.1016/j.algal.2019.101637.
[7] 王立娜, 王家林, 朱涛, 吕雪峰. 蓝细菌基因组拷贝数的研究进展与展望. 生物工程学报[J]. 2018, 34(9): 1386-1397, http://lib.cqvip.com/Qikan/Article/Detail?id=676362701.
[8] Zhu, Tao, Scalvenzi, Thibault, Sassoon, Nathalie, Lu, Xuefeng, Gugger, Muriel. Terminal Olefin Profiles and Phylogenetic Analyses of Olefin Synthases of Diverse Cyanobacterial Species. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2018, 84(13): http://dx.doi.org/10.1128/AEM.00425-18.
[9] 吕雪峰. Terminal olefin profiles and phylogenetic analyses of olefin synthases in diversified cyanobacterial species. Applied and Environmental Microbiology. 2018, [10] Tao Zhu Shengwei Hou Xuefeng Lu Wolfgang R Hess, Xuefeng Lu Wolfgang R Hess. Draft Genome Sequences of Nine Cyanobacterial Strains from Diverse Habitats. GENOMEANNOUNCEMENTS[J]. 2017, 5(9): [11] Mo, Huilin, Xie, Xiaoman, Zhu, Tao, Lu, Xuefeng. Effects of global transcription factor NtcA on photosynthetic production of ethylene in recombinant Synechocystis sp PCC 6803. BIOTECHNOLOGY FOR BIOFUELS[J]. 2017, 10(1): http://dx.doi.org/10.1186/s13068-017-0832-y.
[12] Guan, Wenna, Zhu, Tao, Wang, Yuejie, Zhang, Zhongyi, Jin, Zhao, Wang, Cong, Bai, Fali. Efficacy of head space solid-phase microextraction coupled to gas chromatography-mass spectrometry method for determination of the trace extracellular hydrocarbons of cyanobacteria. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2016, 1029: 113-120, http://dx.doi.org/10.1016/j.jchromb.2016.06.050.
[13] Gao, Hong, Zhu, Tao, Xu, Min, Wang, Shuai, Xu, Xudong, Kong, Renqiu. pH-dependent gas vesicle formation in Microcystis. FEBS LETTERS[J]. 2016, 590(18): 3195-3201, http://ir.ihb.ac.cn/handle/342005/34581, http://www.irgrid.ac.cn/handle/1471x/6853833, http://ir.ihb.ac.cn/handle/342005/34582, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384807700015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=3a85505900f77cc629623c3f2907beab.
[14] Zhu, Tao, Xie, Xiaoman, Li, Zhimin, Tan, Xiaoming, Lu, Xuefeng. Enhancing photosynthetic production of ethylene in genetically engineered Synechocystis sp PCC 6803. GREEN CHEMISTRY[J]. 2015, 17(1): 421-434, [15] Zhu, T., Xie, X., Li, Z., Tan, X., Lu, X.. Enhancing photosynthetic production of ethylene in genetically engineered Synechocystis sp. PCC 6803. GREEN CHEM[J]. 2015, 17(1): 421-434, http://ir.qibebt.ac.cn/handle/337004/8662.
[16] Zhu, T, Xu, X. Efficacy of a dual fluorescence method in detecting the viability of overwintering cyanobacteria. LETTERSINAPPLIEDMICROBIOLOGY[J]. 2013, 57(3): 174-180, http://www.irgrid.ac.cn/handle/1471x/780078.
[17] Liu, Aiqiu, Zhu, Tao, Lu, Xuefeng, Song, Lirong. Hydrocarbon profiles and phylogenetic analyses of diversified cyanobacterial species. APPLIED ENERGY[J]. 2013, 111(2013): 383-393, http://dx.doi.org/10.1016/j.apenergy.2013.05.008.
[18] Tan, Xiaoming, Zhu, Tao, Shen, Si, Yin, Chuntao, Gao, Hong, Xu, Xudong. Role of Rbp1 in the Acquired Chill-Light Tolerance of Cyanobacteria. JOURNAL OF BACTERIOLOGY[J]. 2011, 193(11): 2675-2683, https://www.webofscience.com/wos/woscc/full-record/WOS:000290527900001.

   

（ 1 ） 蓝细菌产脂肪烃种质资源的筛选和产烃关键基因分子进化的研究, 主持, 国家级, 2013-01--2015-12
（ 2 ） 基因工程蓝细菌合成脂肪烃, 主持, 部委级, 2013-04--2016-04
（ 3 ） 蓝细菌末端烯烃合成的分子机制及关键酶的分子进化研究, 主持, 国家级, 2016-01--2019-12
（ 4 ） 高温蓝细菌种质资源的筛选和遗传转化体系的建立, 主持, 市地级, 2018-01--2018-12
（ 5 ） 蓝细菌新型CRISPR基因编辑工具的研究, 主持, 市地级, 2020-01--2021-12
（ 6 ） A novel transposon-associated CRISPR-Cas system in cyanobacteria, 参与, 国家级, 2021-01--2023-12

（1）Spatiotemporal distributions of the central dogma are driven by the circadian clock in cyanobacteria   第一届中德蓝细菌双边会议   2019-09-26
（2）Diverging CRISPR-Cas Systems in Multicellular Cyanobacteria   Tao Zhu, Juliane Behler, Lina Wang, Shengwei Hou, Viktoria Reimann, Hui Li, Xuefeng Lu, Wolfgang R. Hess   2019-03-28
（3）无   第一届蓝细菌论坛   2018-05-12
（4）Hydrocarbons production based on the characterization of their biosynthetic pathways in cyanobacteria   2015代谢工程峰会   2015-11-30
（5）Enhancing photosynthetic production of ethylene by genetic modification of TCA cycle and heterologous expression of 2-oxoglutarate permease in Synechocystis sp. PCC 6803   第二届国际清洁能源科学会议   Xiaoman Xie, Tao Zhu, Zhimin Li, Xiaoming Tan, Xuefeng Lu   2014-04-13
（6）Diversified production profiles of hydrocarbons in different cyanobacterial strains   第13届国际菌种保藏大会   Zhu, T., Liu, A., Lu, X.   2013-09-23