Zhenhua Zheng, Professor, 

Wuhan Institute of Virology, Chinese Academy of Sciences


Research Areas

Molecular mechanism of virus infection and pathogenicity

VIrus-Host interaction

Education experience

2005-2011           Ph.D. in Wuhan Institute of Virology Chinese Academy of Sciences, China

2001-2005           B.S. in Bioengineering, Hubei University, China 


1.       Wei C, Zheng C, Sun J, Luo D, Tang Y, Zhang Y, Ke X, Liu Y, Zheng Z*, Wang H. (2019) Viperin Inhibits Enterovirus A71 Replication by Interacting with Viral 2C Protein. 1. Viruses. 11(1).

2.       Tan Z, Zhang W, Sun J, Fu Z, Ke X, Zheng C, Zhang Y, Li P, Liu Y, Hu Q, Wang H*, Zheng Z* (2018) ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. J Neuroinflammation. 15(1):275.

3.       Li P, Ke X, Wang T, Tan Z, Luo D, Miao Y, Sun J, Zhang Y, Liu Y, Hu Q, Xu F, Wang H*, Zheng Z*. (2018). Zika virus attenuation by codon pair deoptimization induces sterilizing immunity in mouse models. J Virol 92:e00701-18

4.       Liu Y, Tan Z, Shu B, Zhang Y, Zheng C, Ke X, Chen X, Wang H, Zheng Z*. (2017) An improved method for identifying SUMOylation sites of viral proteins. Virologica Sinica. 32:537-540.

5.       Zheng C, Zheng Z*, Sun J, Zhang Y, Wei C, Ke X, Liu Y, Deng L, Wang H. (2017) MiR-16-5p mediates a positive feedback loop in EV71-induced apoptosis and suppresses virus replication. Sci Rep. 7:16422.

6.       Li Q, Zheng Z*, Liu Y, Zhang Z, Liu Q, Meng J, Ke X, Hu Q, Wang H. (2016) 2C Proteins of Enteroviruses Suppress IKKβ Phosphorylation by Recruiting Protein Phosphatase 1. J Virol. 90:5141-51.

7.       Liu Y, Zheng Z*, Shu B, Meng J, Zhang Y, Zheng C, Ke X, Gong P, Hu Q, Wang H. (2016) SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication. J Virol. 90:10472-10485.

8.       Wang M, Zheng Z*, Meng J, Wang H, He M, Zhang F, Liu Y, Hu B, He Z, Hu Q, Wang H. 2015, In vivo study of immunogenicity and kinetic characteristics of a quantum dot-labelled baculovirus. Biomaterials. 64:78-87.

9.       Zheng Z, Wang H. (2013) Tracking viral infection: will quantum dot encapsulation unveil viral mechanisms? Nanomedicine, 8,1225-1227

10.    Zheng Z, Ke X, Wang M, He S, Li Q, Zheng C, Zhang Z, Liu Y, Wang H *. (2013) Human microRNA hsa-miR-296-5p suppresses Enterovirus 71 replication by targeting the viral genome. J Virol., 87, 5645-5656.

11.    Tao L, Chen J, Meng J, Chen Y, Li H, Liu Y, Zheng Z.*, Wang H. (2013) Enhanced protective efficacy of H5 subtype influenza vaccine with modification of the multibasic cleavage site of hemagglutinin in retroviral pseudotypes. Virologica Sinica 28,136-145.

12.    Zheng Z, Li H., Zhang Z., Meng J., Mao D., Bai B., Lu B., Mao P., Hu Q., Wang H*. (2011) Enterovirus 71 2C protein inhibits TNF-α mediated activation of NF-κB by suppressing IκB kinase β phosphorylation. J Immunol. 187,2202-2212. 



唐妍  硕士研究生  085238-生物工程  

韦春雨  硕士研究生  071010-生物化学与分子生物学  

苗元玖  硕士研究生  085238-生物工程  


姚琛  硕士研究生  071010-生物化学与分子生物学  

隋妍  硕士研究生  071005-微生物学  

郑月  硕士研究生  071005-微生物学  

张赛  硕士研究生  071010-生物化学与分子生物学  

Honors & Distinctions

Youth Innovation Promotion Association of Chinses Academy of Sciences (2016302)

The first prize of the fourteenth Hubei Provincial Natural Science outstanding papers (2011)