木薯（Manihot esculenta)和甘薯(Ipomoea batatas)是我国重要的薯类经济作物，特别在粮食安全和农业结构调整中发挥着重要作用。因其适应性强、产量高、应用广泛等特性，成为粮食安全的保障和发展生物质能源的重要原材料。我们的研究目标是利用分子生物学手段解答与木薯和甘薯生产密切关联的基本科学问题，并研发新技术来弥合科学发现和应用之间的差距。通过发掘木薯和甘薯种质，并专注于关键的生物问题，目标是使其更高产、更好的工业应用原材料和有利于在边缘土地生长，以保障粮食安全和营养。我们寻求不同的生物技术方法，以提高木薯和甘薯产量和淀粉品质，增强抗逆性，改善其营养。建立的遗传转化和基于CRISPR/Cas9的基因组编辑系统为研究这两种块根类作物提供了必要的分子工具。主要目标包括：（1）更好地了解块根作物的"源-库"关系;（2）阐释储藏根发育和淀粉积累的分子调控模式;（3）发掘低温、干旱、贫瘠土壤及采后生理性衰变的分子应激反应和遗传改良;（4） 培育高产、高淀粉及营养好的新型品种。

实验室（上海木薯生物技术中心）网站：www.cassavabiotech.org.cn

致力于全球农业发展，对薯类生物技术感兴趣，在植物生理学、分子生物学、生物化学等方面基础好，独立研究能力要强，善于发现问题和提出问题，能够开展田间实验工作。

071001-植物学

薯类生物技术

1998-05--2001-02   瑞士联邦理工大学-苏黎世   博士

2020.05-今，中国科学院分子植物科学卓越创新中心，课题组长、研究员

2005.07-2020.04，中国科学院上海生命科学研究院（植物生理生态研究所），课题组长、研究员

2010.01-2015.12，中国科学院上海辰山植物科学研究中心，课题组长、兼职研究员

2001.02-2005.12，瑞士联邦理工大学-苏黎世（ETH Zurich)，博士后、高级研究助理Oberassistant

1995.08-1997.08，山东省果树研究所，研究实习员

1. 甘薯离体培养不定根生芽方法及其应用。2007.08.01，中国，专利授权号：ZL200710044453.4

2. 调节块根植物淀粉组成的方法。2008.09.05，中国，专利授权号：ZL200810042545.3

3. 一种提高植物抗逆境能力的基因及其用途。中国，专利授权号：ZL201310175390.1

4. 3GGT基因及其编码蛋白在特异性糖基化花青素-3-O-葡糖苷中的应用。中国，专利授权号：201510216003.3

5. 调节薯类叶片中淀粉含量的方法及应用。中国，专利授权号：ZL201510469270.1

6. 调节薯类储藏根性状的方法及应用。中国，专利授权号：ZL201510481265.2

（1） 山东省科技进步奖, 三等奖, 省级, 2019
（2） 中科院网络科普联盟“科普启明星”个人奖, 院级, 2018
（3） 第二届三农科技服务金桥奖, , 其他, 2015
（4） 泰安市科技进步奖, 二等奖, 市地级, 2014
（5） 第八届大北农科技奖促进奖, 其他, 2013
（6） 泰安市科技进步奖, 一等奖, 市地级, 2012
（7） 中国科学院院地合作奖先进个人（科技类）, 一等奖, 部委级, 2011
（8） 明治生命科学奖, 其他, 2011
（9） The Jubilee Prize 2003 of the Eiselen Foundation Ulm, 特等奖, 其他, 2004

发表论文目录：

SCI期刊论文（近5年，按年排序，*通讯作者）

1.     Zhou W#,  Zhao S#, He S, Ma Q, Lu X, Hao X, Wang H, Yang J, Zhang P* (2020) Production of very‐high‐amylose cassava by post transcriptional silencing of branching enzyme genes. Journal of Integrative Plant Biology 62(6): 832-846. (Cover story)

http://dx.doi.org/10.1111/jipb.12848

2.     Wang H#, Wu Y#, Zhang Y, Yang J, Fan W, Zhang H, Zhao S, Yuan L*, Zhang P* (2019) CRISPR/Cas9-based mutagenesis of starch biosynthetic genes in sweet potato (Ipomoea batatas) for the improvement of starch quality. International Journal of Molecular Sciences 20:4702.

https://doi.org/10.3390/ijms20194702

3.     Zhang B, Zhou W, Qiao D, Zhang P*, Zhao S-m, Zhang L, Xie F* (2019) Changes in nanoscale chain assembly in sweet potato starch lamellae by downregulation of biosynthesis enzymes. Journal of Agricultural and Food Chemistry 67: 6302-6312. (Cover story)

http://dx.doi.org/10.1021/acs.jafc.8b06523

4.     Zhang Y, Deng G, Fan W, Yuan L, Wang H*, Zhang P* (2019) NHX1 and eIF4A1‑stacked transgenic sweetpotato shows enhanced tolerance to drought stress. Plant Cell Reports 38:1427-1438.

http://dx.doi.org/10.1007/s00299-019-02454-6

5.     Zhong Y, Ahmed S, Deng G, Fan W, Zhang P*, Wang H* (2019) Improved insect resistance against Spodoptera litura in transgenic sweetpotato by overexpressing Cry1Aa toxin. Plant Cell Reports 38:1439-1448.

http://dx.doi.org/10.1007/s00299-019-02460-8

6.     Yan W#, Wu X#, Li Y, Liu G, Jiang T, Cui Z, Ma Q, Luo L*, Zhang P* (2019) Cell wall invertase 3 affects cassava productivity via regulating sugar allocation from source to sink. Frontiers in Plant Science, 10: 541.

https://doi.org/10.3389/fpls.2019.00541

7.     Wang H*, Wang C, Fan W, Yang J, Appelhagen I, Wu Y, Zhang P* (2018) A novel glycosyltransferase catalyses the transfer of glucose to glucosylated anthocyanins in purple sweet potato Journal of Experimental Botany 69(22):5444-5459.

http://dx.doi.org/10.1093/jxb/ery305

8.     Zhang P*, Fan W, Wang H, Wu Y, Zhou W, Yang J (2018) Developing new sweet potato varieties with improved performance. In: Wang-Pruski G (Ed.) Achieving sustainable cultivation of potatoes Volume 1, Breeding improved varieties. Burleigh Dodds Science Publishing, Cambridge UK.

http://dx.doi.org/10.19103/AS.2017.0016.08

9.     Zhang P*, Ma Q, Naconsie M, Wu X, Zhou W, Yang J (2017) Advances in genetic modification of cassava. In: Hershey C (Ed.) Achieving sustainable cultivation of cassava Volume 2, Genetics, breeding, pests and diseases. Burleigh Dodds Science Publishing, Cambridge UK.

http://dx.doi.org/10.19103/AS.2016.0014.17

10.   Bi H, Fan W, Zhang P* (2017) C4 protein of Sweet Potato Leaf Curl Virus regulates brassinosteroid signaling pathway through interaction with AtBIN2 and affects male fertility in Arabidopsis. Frontiers in Plant Science 8:1689.

http://dx.doi.org/10.3389/fpls.2017.01689

11.   Yang J, Moeinzadeh M-H, Kuhl H, Helmuth J, Xiao P, Haas S, Liu G, Zheng J, Sun Z, Fan W, Deng G, Wang H, Hu F, Zhao S, Fernie AR, Boerno S, Timmermann B, Zhang P*, Vingron M* (2017) Haplotype-resolved sweet potato genome traces back its hexaploidization history. Nature Plants 3: 696-703.

http://dx.doi.org/10.1038/s41477-017-0002-z

12.   Zhou W, He S, Naconsie M, Ma Q, Zeeman SC, Gruissem W, Zhang P* (2017) Alpha-glucan, water dikinase 1 affects starch metabolism and storage root growth in cassava (Manihot esculenta Crantz). Scientific Reports 7: 9863

http://dx.doi.org/10.1038/s41598-017-10594-6

13.   Shi S, Zhang X, Mandel MA, Zhang P, Zhang Y, Ferguson M, Amuge T, Rounsley S, Liu Z*, Xiong Z* (2017) Variations of five eIF4E genes across cassava accessions exhibiting tolerant and susceptible responses to cassava brown streak disease. PLoS ONE 12(8): e0181998.

http://dx.doi.org/10.1371/journal.pone.0181998

14.   Ruan M-B*, Guo X, Wang B, Yang Y-L, Li W-Q, Yu X-L, Zhang P, Peng M* (2017) Genome-wide characterization and expression analysis enables identification of abiotic stress-responsive MYB transcription factors in cassava (Manihot esculenta). Journal of Experimental Botany 68(13): 3657-3672.

http://dx.doi.org/10.1093/jxb/erx202

15.   Ge J, Hu Y, Wang H, Huang Y, Zhang P*, Liao Z*, Chen M* (2017) Profiling of anthocyanins in transgenic purple-fleshed sweet potatoes by HPLC-MS/MS. Journal of the Science of Food and Agriculture 97(14): 4995-5003.

http://dx.doi.org/10.1002/jsfa.8379

16.   An D, Ma Q, Wang H, Yang J, Zhou W, Zhang P* (2017) Cassava C-repeat binding factor 1 gene responds to low temperature and enhances cold tolerance when overexpressed in Arabidopsis and cassava. Plant Molecular Biology 94(1-2): 109-124.

http://dx.doi.org/10.1007/s11103-017-0596-6

17.   Fan WJ, Wang HX, Wu YL, Yang N, Yang J, Zhang P* (2017) H+-pyrophosphatase IbVP1 promotes efficient iron use in sweet potato [Ipomoea batatas (L.) Lam.]. Plant Biotechnology Journal 15: 698-712.

http://dx.doi.org/10.1111/pbi.12667

18.   Lu F, Liang X, Lu H, Li Q, Chen Q*, Zhang P*, Li K*, Liu G, Yan W, Song J, Duan C, Zhang L (2017) Overproduction of superoxide dismutase and catalase confers cassava resistance to Tetranychus cinnabarinus. Scientific Reports 7: 40179.

http://dx.doi.org/10.1038/srep40179

19.   Naconsie M, Zhang P* (2016) Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy for food security in Africa. Frontiers of Agricultural Science and Engineering 3(4): 285-294. (Review)

http://dx.doi.org/10.15302/J-FASE-2016119

20.   An D, Ma Q, Yan W, Zhou W, Liu G, Zhang P* (2016) Divergent regulation of CBF regulon on cold tolerance and plant phenotype in cassava overexpressing Arabidopsis CBF3 gene. Frontiers in Plant Science 7:1866.

http://dx.doi.org/10.3389/fpls.2016.01866

21.   Fan W, Wang H, Zhang P* (2016) Engineering glycinebetaine metabolism for enhanced drought stress tolerance in plants. In: Hossain MA et al. (Eds.), Drought Stress Tolerance in Plants, Volume 2, Molecular and Genetic Perspectives. Chapter 18, pp. 513-530. Springer International Publishing Switzerland, 2016. (Review)

http://dx.doi.org/10.1007/978-3-319-32423-4_18

22.   Ma Q, Zhang T, Zhang P*, Wang Z-Y*. (2016) Melatonin attenuates postharvest physiological deterioration of cassava storage roots. Journal of Pineal Research 60(4): 424-434.

http://dx.doi.org/10.1111/jpi.12325

23.   Liao WB, Wang G, Li YY, Wang B, Zhang P*, Peng M* (2016) Reactive oxygen species regulate leaf pulvinus abscission zone cell separation in response to water-deficit stress in cassava. Scientific Reports 6: 21542.

http://dx.doi.org/10.1038/srep21542

24.   Wang H, Yang J, Zhang M, Fan W, Firon N, Pattanaik S, Yuan L, Zhang P* (2016) Altered phenylpropanoid metabolism in the maize Lc-expressed sweet potato (Ipomoea batatas) affects storage root development. Scientific Reports 6: 18645.

http://dx.doi.org/10.1038/srep18645