1. The molecular mechanism underlying extreme stress tolerance of some plants

2. RNA-directed DNA methylation

2003.08 - 2009.08, Purdue University, Ph.D. in Biochemistry

1999.09 - 2003.07, Peking University, B.S. in Biotechnology

   

2009.08 - 2011.12, Purdue University, postdoc fellow

First author and corresponding author papers:

（1） A high-quality genome assembly of quinoa provides insights into the molecular basis of salt bladder-based salinity tolerance and the exceptional nutritional value, Cell Research, 2017

（2） The developmental regulator PKL is required to maintain correct DNA methylation patterns at RNA-directed DNA methylation loci, Genome Biol, 2017

（3） Protecting genes from RNA silencing by destroying aberrant transcripts, Sci China Life Sci, 2015

（4） Involvement of Multiple Gene-Silencing Pathways in a Paramutation-like Phenomenon in Arabidopsis, Cell Reports, 2015

（5） Comparative physiological, metabolomic, and transcriptomic analyses reveal mechanisms of improved abiotic stress resistance in bermudagrass [Cynodon dactylon (L). Pers.] by exogenous melatonin, J Exp Bot, 2015
（6） RNA-directed DNA methylation in plants: Where to start?, RNA Biology, 2013
（7） DTF1 is a core component of the RNA-directed DNA methylation and may assist in the recruitment of Pol IV, Proc Natl Acad Sci USA, 2013

（8） The CHD3 remodeler PICKLE associates with genes enriched for trimethylation of histone H3 lysine 27, Plant Physiol, 2012
（9） An epigenetic perspective on developmental regulation of seed genes, Mol Plant, 2009
（10） The CHD3 remodeler PICKLE promotes trimethylation of histone H3 lysine 27, J Biol Chem, 2008

Collaboration papers:

（1） Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma, Nature Material, 2017
（2） DNA methylation markers for diagnosis and prognosis of common cancers, PNAS, 2017
（3） A protein complex regulates RNA processing of intronic heterochromatin-containing genes in Arabidopsis, PNAS, 2017
（4） A pair of transposon-derived proteins function in a histone acetyltransferase complex for active DNA demethylation, Cell Research, 2017
（5） Dicer-independent RNA-directed DNA methylation in Arabidopsis, Cell Res, 2016, 第 7 作者
（6） The DNA demethylase ROS1 targets genomic regions with distinct chromatin modifications, Nat Plants, 2016
（7） PKL is a CHD subfamily II ATP-dependent chromatin remodeling factor, Biochim Biophys Acta, 2012
（8） A histone acetyltransferase regulates active DNA demethylation in Arabidopsis, Science, 2012

现指导学生

熊贤淞  博士研究生  071007-遗传学  

宋哲  博士研究生  071007-遗传学  

孔祥锋  博士研究生  071007-遗传学  

李静雯  博士研究生  071007-遗传学  

庞佳  硕士研究生  071010-生物化学与分子生物学  

周依婷  硕士研究生  071009-细胞生物学  

周振宇  硕士研究生  071010-生物化学与分子生物学  

王应英  硕士研究生  071010-生物化学与分子生物学  

田益夫  硕士研究生  071007-遗传学  

张哲霆  硕士研究生  071007-遗传学  

马昱冰  硕士研究生  0710J3-生物信息学