干细胞调控与组织器官再生

   

071009-细胞生物学
071008-发育生物学
0710J6-再生医学

再生生物学，干细胞调控，单细胞生物学
组织器官再生

2006-09--2013-07   中科院上海生命科学研究院   博士学位

   

2013-10~2019-09,美国Stowers研究所/HHMI研究所, 博士后研究员

   

（1） 上海市研究生优秀成果（学位论文）, , 省级, 2015
（2） 中国科学院院长优秀奖, , 院级, 2013

   

（1） Integrin αEβ7+ T cells direct intestinal stem cell fate decisions via adhesion signaling, Cell Research, 2021, 通讯作者
（2） Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates, SCIENCE, 2020, 第 3 作者
（3） Heat shock protein DNAJA1 stabilizes PIWI proteins to support regeneration and homeostasis of planarian Schmidtea mediterranea, The Journal of Biological Chemistry, 2019, 第 6 作者
（4） Prospectively Isolated Tetraspanin+ Neoblasts Are Adult Pluripotent Stem Cells Underlying Planaria Regeneration, CELL, 2018, 第 1 作者
（5） Dynamic regulation of small RNAome during the early stage of cardiac differentiation from pluripotent embryonic stem cells, Genomics Data, 2017, 第 1 作者
（6） Small RNAome sequencing delineates the small RNA landscape of pluripotent adult stem cells in the planarian Schmidtea mediterranea, Genomics Data, 2017, 第 1 作者
（7） Elevated microRNA-155 promotes foam cell formation by targeting HBP1 in atherogenesis, CARDIOVASCULAR RESEARCH, 2014, 第 7 作者
（8） Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells, JOURNAL OF CELL BIOLOGY, 2013, 第 1 作者
（9） AU-Rich-Element-Dependent Translation Repression Requires the Cooperation of Tristetraprolin and RCK/P54, MOLECULAR AND CELLULAR BIOLOGY, 2012, 第 5 作者
（10） Argonaute-2 regulates the proliferation of adult stem cells in planarian, Argonaute-2 regulates the proliferation of adult stem cells in planarian, CELL RESEARCH, 2011, 第 2 作者

   

（ 1 ） 中科院****, 负责人, 中国科学院计划, 2020-01--2022-12
（ 2 ） 单细胞水平解析涡虫TSPAN1+成体多能干细胞调控机制, 负责人, 国家任务, 2021-01--2024-12
（ 3 ） 干细胞模拟胚胎发育和器官发生的机制研究及其转化应用, 负责人, 国家任务, 2020-10--2024-12

（1）Maintenance and regulation of adult pluripotency during planarian regeneration   2019-09-17
（2）Prospectively isolated Tetraspanin+ neoblasts are adult pluripotent stem cells underlying planaria regeneration   2018-07-12
（3）Heterochromatin protein 1 determines self-renewal and triggers regenerative proliferation in adult stem cells   2012-12-04