基本信息

姚伦  男    中国科学院大连化学物理研究所
电子邮件: yaolun@dicp.ac.cn
地址: 辽宁省大连市沙河口区中山路457号大连化物所生物楼

研究领域

甲醇微生物合成生物学与系统生物学

微生物代谢工程

招生信息

欢迎生物相关背景同学报名!

招生专业
081703-生物化工
招生方向
甲醇酵母合成生物学与系统生物学
微生物代谢工程

教育背景

2008-09--2013-07   中国科学院大学(青岛生物能源与过程研究所)   理学博士学位
2004-09--2008-06   兰州大学   理学学士学位

工作经历

2021-01~现在, 中国科学院大连化学物理研究所, 副研究员
2014-05~2019-11,瑞典皇家理工学院, 博士后


专利与奖励

   
奖励信息
(1) 山东省科学技术奖, 二等奖, 省级, 2017
专利成果
[1] 吕雪峰, 吴伟, 姚伦. 一种检测微生物细胞中脂肪烃的构建体及利用构建体原位检测脂肪烃的方法. CN: CN105463005B, 2020-01-21.
[2] 吕雪峰, 谈晓明, 姚伦, 高倩倩, 齐凤霞. 用于合成脂肪醇的构建体,载体,蓝细菌,以 及在蓝细菌中生产脂肪醇的方法. 中国: CN102311966A, 2012-01-11.

出版信息

   
发表论文
[1] Yan, Chunxiao, Yu, Wei, Zhai, Xiaoxin, Yao, Lun, Guo, Xiaoyu, Gao, Jiaoqi, Zhou, Yongjin J. Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha. SYNTHETIC AND SYSTEMS BIOTECHNOLOGY[J]. 2022, 7(1): 498-505, http://dx.doi.org/10.1016/j.synbio.2021.12.005.
[2] Marina Santos, Catarina C Pacheco, Lun Yao, Elton P Hudson, Paula Tamagnini, Paul M DAgostino, Ndia Eusbio, ngela Brito. CRISPRi as a Tool to Repress Multiple Copies of Extracellular Polymeric Substances (EPS)-Related Genes in the Cyanobacterium Synechocystis sp. PCC 6803. Life. 2021, 11(11): [3] Lun Yao, Kiyan Shabestary, Sara M Bjrk, Johannes AsplundSamuelsson, Haakan N Joensson, Michael Jahn, Elton P Hudson. Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes. NATURE COMMUNICATIONS[J]. 2020, 11(1): http://dx.doi.org/10.1038/s41467-020-15491-7.
[4] Shabestary, Kiyan, Anfelt, Josefine, Ljungqvist, Emil, Jahn, Michael, Yao, Lun, Hudson, Elton P. Targeted Repression of Essential Genes To Arrest Growth and Increase Carbon Partitioning and Biofuel Titers in Cyanobacteria. ACS SYNTHETIC BIOLOGY[J]. 2018, 7(7): 1669-1675, https://www.webofscience.com/wos/woscc/full-record/WOS:000439761800003.
[5] Kaczmarzyk, Danuta, Cengic, Ivana, Yao, Lun, Hudson, Elton P. Diversion of the long-chain acyl-ACP pool in Synechocystis to fatty alcohols through CRISPRi repression of the essential phosphate acyltransferase PlsX. METABOLIC ENGINEERING[J]. 2018, 45: 59-66, http://dx.doi.org/10.1016/j.ymben.2017.11.014.
[6] Yao, Lun, Cengic, Ivana, Anfelt, Josefine, Hudson, Elton P. Multiple Gene Repression in Cyanobacteria Using CRISPRi. ACS SYNTHETIC BIOLOGY[J]. 2016, 5(3): 207-212, https://www.webofscience.com/wos/woscc/full-record/WOS:000372672500003.
[7] Wu, Wei, Zhang, Lei, Yao, Lun, Tan, Xiaoming, Liu, Xufeng, Lu, Xuefeng. Genetically assembled fluorescent biosensor for in situ detection of bio-synthesized alkanes. SCIENTIFIC REPORTS[J]. 2015, 5: http://ir.qibebt.ac.cn/handle/337004/6776.
[8] Yao, Lun, Qi, Fengxia, Tan, Xiaoming, Lu, Xuefeng. Improved production of fatty alcohols in cyanobacteria by metabolic engineering. BIOTECHNOLOGY FOR BIOFUELS[J]. 2014, 7(1): 94-94, http://www.irgrid.ac.cn/handle/1471x/1001224.
[9] Qi, Fengxia, Yao, Lun, Tan, Xiaoming, Lu, Xuefeng. Construction, characterization and application of molecular tools for metabolic engineering of Synechocystis sp.. BIOTECHNOLOGY LETTERS[J]. 2013, 35(10): 1655-1661, http://www.irgrid.ac.cn/handle/1471x/830101.
[10] Liu, Aiqiu, Tan, Xiaoming, Yao, Lun, Lu, Xuefeng. Fatty alcohol production in engineered E-coli expressing Marinobacter fatty acyl-CoA reductases. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2013, 97(15): 7061-7071, http://www.irgrid.ac.cn/handle/1471x/1001220.
[11] Tan, Xiaoming, Yao, Lun, Gao, Qianqian, Wang, Weihua, Qi, Fengxia, Lu, Xuefeng. Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria. METABOLIC ENGINEERING[J]. 2011, 13(2): 169-176, http://dx.doi.org/10.1016/j.ymben.2011.01.001.