基本信息

李洋 男 硕导 中国科学院深圳先进技术研究院
电子邮件: yang.li@siat.ac.cn
通信地址: 中科院深圳医药所纳米中心
邮政编码:
电子邮件: yang.li@siat.ac.cn
通信地址: 中科院深圳医药所纳米中心
邮政编码:
研究领域
1) 癌症免疫学(肿瘤免疫治疗)
2) 纳米医学(纳米药物的肿瘤靶向与免疫治疗)
3) 免疫学(巨噬细胞,IL-1家族,炎症因子)
4) 纳米免疫安全性 (纳米毒理学)
招生信息
1) 免疫学,生物学
2) 纳米医学,纳米生物学
3) 化学(化学生物学)
招生专业
071010-生物化学与分子生物学0703J1-纳米科学与技术100102-免疫学
招生方向
纳米医学,纳米免疫安全性癌症免疫,免疫检查点治疗天然免疫系统,天然免疫记忆
教育背景
2011-11--2014-10 萨尔斯堡大学 博士
工作经历
工作简历
2016-09~2018-06,科罗拉多大学, 博士后2015-07~2016-08,堪萨斯纳米技术研发中心, 博士后2014-10~2014-12,意大利国家科学院, 博士后2011-10~2014-10,意大利国家研究院, 玛丽居里研究员/博士
专利与奖励
奖励信息
(1) 国际纳米毒理学大会旅行奖, 一等奖, 专项, 2016(2) 优秀自费留学生奖学金, 一等奖, 国家级, 2013(3) 玛丽居里奖学金, 一等奖, 其他, 2011
出版信息
发表论文
(1) Modulation of the inflammatory tumor microenvironment - a new approach for photothermal-synergized cancer immunotherapy, Nanomedicine, 2019, 通讯作者(2) Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation, Nanotoxicology, 2017, 第 1 作者(3) Endotoxin contamination in nanomaterials leads to the misinterpretation of immunosafety results, Frontiers in immunology, 2017, 第 1 作者(4) An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanoma, Journal of Investigative Dermatology, 2017, 第 1 作者(5) Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles, Nanomedicine, 2016, 第 1 作者(6) Endotoxin contamination: a key element in the interpretation of nanosafety studies, Nanomedicine, 2016, 第 1 作者(7) Assessing the Immunosafety of Engineered Nanoparticles with a Novel in Vitro Model Based on Human Primary Monocytes, ACS Applied Materials & Interfaces, 2016, 第 1 作者(8) Optimising the use of commercial LAL assays for the analysis of endotoxin contamination in metal colloids and metal oxide nanoparticles, Nanotoxicology, 2015, 第 1 作者(9) Uptake and bio-reactivity of polystyrene nanoparticles is affected by surface modifications, ageing and LPS adsorption: in vitro studies on neural tissue cells, Nanoscale, 2015, 第 3 作者(10) Multiwall Carbon Nanotubes Mediate Macrophage Activation and Promote Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway, Small, 2013, 第 4 作者(11) The contributions of metal impurities and tube structure to the toxicity of carbon nanotube materials, NPG Asia Materials, 2012, 第 2 作者(12) Acute pulmonary and moderate cardiovascular responses of spontaneously hypertensive rats after exposure to single-wall carbon nanotubes, Nanotoxicology, 2012, 第 7 作者(13) The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways, Biomaterials, 2012, 第 1 作者
科研活动
科研项目
( 1 ) 纳米颗粒蛋白质晕(biocorona)对炎症小体激活和白介素1分泌的调控, 主持, 国家级, 2018-01--2020-12
参与会议
(1)Autoinflammation from the imbalance of IL-1 over IL-1Ra contributes to tumor progression in metastatic melanoma Yang Li 2017-08-26(2)An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanoma Yang Li 2017-04-26(3)Protein coronas affect the mechanisms of cell uptake and inflammatory effects of gold nanoparticles 2016-10-26(4)Cellular uptake mechanism of gold nanoparticles with three different surface coatings and protein corona effects on cell uptake in human epidermal keratinocytes 2016-06-01(5)Evaluating engineered nanoparticle immunosafety: effects on the course of the innate immune reaction of human primary monocytes in vitro 2014-06-18(6)Bacterial endotoxin binds to the surface of gold nanoparticles and triggers inflammation 2014-04-23(7)An in vitro model based on human primary monocytes for evaluating the effects of engineered nanoparticles on the course of an inflammatory defence reaction 2014-04-23(8)Assessing interference of nanoparticles with the inflammatory response by a novel in vitro model based on human primary monocytes 2013-09-05(9)Assessing immune toxicity of engineered nanoparticles: modulation of inflammation in a novel in vitro model based on human primary monocytes Yang LI 2013-08-22(10)Human primary monocytes as reference cells for assessing interference of nanoparticles with the inflammatory defence reaction Yang Li 2013-02-27(11)The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways 2012-09-04(12)The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways 2012-02-27