1）  癌症免疫学（肿瘤免疫治疗）

2）  纳米医学（纳米药物的肿瘤靶向与免疫治疗）

3）  免疫学（巨噬细胞，IL-1家族，炎症因子）

4）  纳米免疫安全性 （纳米毒理学）

1）  免疫学,生物学

2）  纳米医学，纳米生物学

3）  化学（化学生物学）

071010-生物化学与分子生物学
0703J1-纳米科学与技术
100102-免疫学

纳米医学，纳米免疫安全性
癌症免疫，免疫检查点治疗
天然免疫系统，天然免疫记忆

2011-11--2014-10   萨尔斯堡大学   博士

   

2016-09~2018-06,科罗拉多大学, 博士后
2015-07~2016-08,堪萨斯纳米技术研发中心, 博士后
2014-10~2014-12,意大利国家科学院, 博士后
2011-10~2014-10,意大利国家研究院, 玛丽居里研究员/博士

   

（1） 国际纳米毒理学大会旅行奖, 一等奖, 专项, 2016
（2） 优秀自费留学生奖学金, 一等奖, 国家级, 2013
（3） 玛丽居里奖学金, 一等奖, 其他, 2011

   

（1） Modulation of the inflammatory tumor microenvironment - a new approach for photothermal-synergized cancer immunotherapy, Nanomedicine, 2019, 通讯作者
（2） Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation, Nanotoxicology, 2017, 第 1 作者
（3） Endotoxin contamination in nanomaterials leads to the misinterpretation of immunosafety results, Frontiers in immunology, 2017, 第 1 作者
（4） An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanoma, Journal of Investigative Dermatology, 2017, 第 1 作者
（5） Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles, Nanomedicine, 2016, 第 1 作者
（6） Endotoxin contamination: a key element in the interpretation of nanosafety studies, Nanomedicine, 2016, 第 1 作者
（7） Assessing the Immunosafety of Engineered Nanoparticles with a Novel in Vitro Model Based on Human Primary Monocytes, ACS Applied Materials & Interfaces, 2016, 第 1 作者
（8） Optimising the use of commercial LAL assays for the analysis of endotoxin contamination in metal colloids and metal oxide nanoparticles, Nanotoxicology, 2015, 第 1 作者
（9） Uptake and bio-reactivity of polystyrene nanoparticles is affected by surface modifications, ageing and LPS adsorption: in vitro studies on neural tissue cells, Nanoscale, 2015, 第 3 作者
（10） Multiwall Carbon Nanotubes Mediate Macrophage Activation and Promote Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway, Small, 2013, 第 4 作者
（11） The contributions of metal impurities and tube structure to the toxicity of carbon nanotube materials, NPG Asia Materials, 2012, 第 2 作者
（12） Acute pulmonary and moderate cardiovascular responses of spontaneously hypertensive rats after exposure to single-wall carbon nanotubes, Nanotoxicology, 2012, 第 7 作者
（13） The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways, Biomaterials, 2012, 第 1 作者

   

（ 1 ） 纳米颗粒蛋白质晕(biocorona)对炎症小体激活和白介素1分泌的调控, 主持, 国家级, 2018-01--2020-12

（1）Autoinflammation from the imbalance of IL-1 over IL-1Ra contributes to tumor progression in metastatic melanoma   Yang Li   2017-08-26
（2）An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanoma   Yang Li   2017-04-26
（3）Protein coronas affect the mechanisms of cell uptake and inflammatory effects of gold nanoparticles   2016-10-26
（4）Cellular uptake mechanism of gold nanoparticles with three different surface coatings and protein corona effects on cell uptake in human epidermal keratinocytes   2016-06-01
（5）Evaluating engineered nanoparticle immunosafety: effects on the course of the innate immune reaction of human primary monocytes in vitro   2014-06-18
（6）Bacterial endotoxin binds to the surface of gold nanoparticles and triggers inflammation   2014-04-23
（7）An in vitro model based on human primary monocytes for evaluating the effects of engineered nanoparticles on the course of an inflammatory defence reaction   2014-04-23
（8）Assessing interference of nanoparticles with the inflammatory response by a novel in vitro model based on human primary monocytes   2013-09-05
（9）Assessing immune toxicity of engineered nanoparticles: modulation of inflammation in a novel in vitro model based on human primary monocytes   Yang LI   2013-08-22
（10）Human primary monocytes as reference cells for assessing interference of nanoparticles with the inflammatory defence reaction   Yang Li   2013-02-27
（11）The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways   2012-09-04
（12）The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways   2012-02-27