基本信息
李洋  男  硕导  中国科学院深圳先进技术研究院
电子邮件: yang.li@siat.ac.cn
通信地址: 中科院深圳医药所纳米中心
邮政编码:
部门/实验室:医药所

招生信息

1)  免疫学,生物学

2)  纳米医学,纳米生物学

3)  化学(化学生物学)


招生专业
071010-生物化学与分子生物学
0703J1-纳米科学与技术
100102-免疫学
招生方向
纳米医学,纳米免疫安全性
癌症免疫,免疫检查点治疗
天然免疫系统,天然免疫记忆

教育背景

2011-11--2014-10   萨尔斯堡大学   博士

工作经历

   
工作简历
2016-09~2018-06,科罗拉多大学, 博士后
2015-07~2016-08,堪萨斯纳米技术研发中心, 博士后
2014-10~2014-12,意大利国家科学院, 博士后
2011-10~2014-10,意大利国家研究院, 玛丽居里研究员/博士

专利与奖励

   
奖励信息
(1) 国际纳米毒理学大会旅行奖, 一等奖, 专项, 2016
(2) 优秀自费留学生奖学金, 一等奖, 国家级, 2013
(3) 玛丽居里奖学金, 一等奖, 其他, 2011

出版信息

   
发表论文
(1) Modulation of the inflammatory tumor microenvironment - a new approach for photothermal-synergized cancer immunotherapy, Nanomedicine, 2019, 通讯作者
(2) Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation, Nanotoxicology, 2017, 第 1 作者
(3) Endotoxin contamination in nanomaterials leads to the misinterpretation of immunosafety results, Frontiers in immunology, 2017, 第 1 作者
(4) An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanoma, Journal of Investigative Dermatology, 2017, 第 1 作者
(5) Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles, Nanomedicine, 2016, 第 1 作者
(6) Endotoxin contamination: a key element in the interpretation of nanosafety studies, Nanomedicine, 2016, 第 1 作者
(7) Assessing the Immunosafety of Engineered Nanoparticles with a Novel in Vitro Model Based on Human Primary Monocytes, ACS Applied Materials & Interfaces, 2016, 第 1 作者
(8) Optimising the use of commercial LAL assays for the analysis of endotoxin contamination in metal colloids and metal oxide nanoparticles, Nanotoxicology, 2015, 第 1 作者
(9) Uptake and bio-reactivity of polystyrene nanoparticles is affected by surface modifications, ageing and LPS adsorption: in vitro studies on neural tissue cells, Nanoscale, 2015, 第 3 作者
(10) Multiwall Carbon Nanotubes Mediate Macrophage Activation and Promote Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway, Small, 2013, 第 4 作者
(11) The contributions of metal impurities and tube structure to the toxicity of carbon nanotube materials, NPG Asia Materials, 2012, 第 2 作者
(12) Acute pulmonary and moderate cardiovascular responses of spontaneously hypertensive rats after exposure to single-wall carbon nanotubes, Nanotoxicology, 2012, 第 7 作者
(13) The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways, Biomaterials, 2012, 第 1 作者

科研活动

   
科研项目
( 1 ) 纳米颗粒蛋白质晕(biocorona)对炎症小体激活和白介素1分泌的调控, 主持, 国家级, 2018-01--2020-12
参与会议
(1)Autoinflammation from the imbalance of IL-1 over IL-1Ra contributes to tumor progression in metastatic melanoma   Yang Li   2017-08-26
(2)An imbalance between IL-1 and IL-1Ra in human melanoma cells accounts for autoinflammation and contributes to tumor progression in metastatic melanoma   Yang Li   2017-04-26
(3)Protein coronas affect the mechanisms of cell uptake and inflammatory effects of gold nanoparticles   2016-10-26
(4)Cellular uptake mechanism of gold nanoparticles with three different surface coatings and protein corona effects on cell uptake in human epidermal keratinocytes   2016-06-01
(5)Evaluating engineered nanoparticle immunosafety: effects on the course of the innate immune reaction of human primary monocytes in vitro   2014-06-18
(6)Bacterial endotoxin binds to the surface of gold nanoparticles and triggers inflammation   2014-04-23
(7)An in vitro model based on human primary monocytes for evaluating the effects of engineered nanoparticles on the course of an inflammatory defence reaction   2014-04-23
(8)Assessing interference of nanoparticles with the inflammatory response by a novel in vitro model based on human primary monocytes   2013-09-05
(9)Assessing immune toxicity of engineered nanoparticles: modulation of inflammation in a novel in vitro model based on human primary monocytes   Yang LI   2013-08-22
(10)Human primary monocytes as reference cells for assessing interference of nanoparticles with the inflammatory defence reaction   Yang Li   2013-02-27
(11)The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways   2012-09-04
(12)The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways   2012-02-27

合作情况