General

Bao Yang, PhD, Professor
Functional Food Science Group

South China Botanical Garden (Formerly South China Institute of Botany)

Chinese Academy of Sciences

Email: yangbao@scbg.ac.cn
Address: 723 Xingke Road, Tianhe District, Guangzhou 510650, China


Research Areas

◆ Identification of novel prenylated phenolics and polysaccharides from edible plants , evaluation of their biological activities and mechanisms.

Exploring novel enzymes for heterologously biological synthesis of prenylated phenolics by metabolic engineering.



Experience

2006.06-2008.07, Postdoctor, South China Botanical Garden, Chinese Academy of Sciences

2008.07-2013.12, Associate Professor, South China Botanical Garden, Chinese Academy of Sciences

2012.3-2013.3, Visiting Scholar, Purdue University, USA

2014.01-present, Professor, South China Botanical Garden, Chinese Academy of Sciences

Honors & Distinctions

Top Cited Scholar of China (Elsevier database).

LUJIAXI Outstanding Young Scholar Award winner of Chinese Academy of Sciences.

Editorial board member of Food Chemistry (IF9.2) and Food Chemistry:X (IF6.4).


 


Publications

Chen Yipeng, Jiang Yueming, Wen Lingrong, Yang Bao*. Structure, stability and bioaccessibility of icaritin-loaded pectin nanoparticle. Food Hydrocolloids, 2022, 129, 107663.

Sheng Zhili, Wen Lingrong, Yang Bao*. Structure identification of a polysaccharide in mushroom Lingzhi spore and its immunomodulatory activity. Carbohydrate Polymers, 2022, 278, 118939.

Bo Shengtao, Chang Sui Kiat, Zhu Hong, Jiang Yueming, Yang Bao*. Naturally occurring prenylated stilbenoids - food sources, biosynthesis, applications and health benefits. Critical Reviews in Food Science and Nutrition, in press.

Bo Shengtao, Chang Sui Kiat, Zhou Ting, Zhu Hong, Jiang Yueming, Yang Bao*. Heterologous biosynthesis of prenylated resveratrol and evaluation of antioxidant activity. Food Chemistry, 2022, 378, 132118.

Zhou Ting, Yang Bao*. Novel strategy to produce prenylated resveratrol by prenyltransferase iacE and evaluation of neuroprotective mechanisms. Biochemical and Biophysical Research Communications, 2022, 609, 127-133.

Wen Lingrong, Sheng Zhili, Wang Jinping, Jiang Yueming, Yang Bao*. Structure of water-soluble polysaccharides in spore of Ganoderma lucidum and their anti-inflammatory activity. Food Chemistry, 2022, 373, 131374.

Wen Lingrong, Bi Huimin, Zhou Xuesong, Jiang Yueming, Zhu Hong, Fu Xiong, Yang Bao*. Structure characterization of soybean peptides and their protective activity against intestinal inflammation. Food Chemistry, 2022, 387, 132868.

Xu Meijuan, Zou Jian, Zhao Xiaodong, Feng Yongting, Duan Ruoyu, Yang Bao*. Effect of lactobacteria fermentation on structure and physicochemical properties of Chinese yam starch (Dioscorea opposita Thunb.). Food Chemistry, 2022, 387, 132873.

Wen Lingrong, Zhou Ting, Jiang Yueming, Chang Sui Kiat, Yang Bao*. Prenylated flavonoids in foods and their applications on cancer prevention. Critical Reviews in Food Science and Nutrition, 2021, https://doi.org/10.1080/10408398.2021.1881437.

Wen Lingrong, Jiang Yueming, Zhou Xuesong, Bi Huimin, Yang Bao*. Structure identification of soybean peptides and their immunomodulatory activity. Food Chemistry, 2021, 359, 129970.

Wen Lingrong, He Mingyang, Yin Chunxiao, Jiang Yueming, Luo Donghui, Yang Bao*. Phenolics in Citrus aurantium fruit identified by UHPLC-MS/MS and their bioactivities. LWT-Food Science and Technology, 2021, 147, 111671.

Zhou Ting, Jiang Yueming, Wen Lingrong, Yang Bao*. Characterization of polysaccharide structure in Citrus reticulate ‘Chachi’ peel during storage and their bioactivity. Carbohydrate Research, 2021, 508, 108398.

Sheng Zhili, Liu Junmei, Yang Bao*. Structure differences of water soluble polysaccharides in Astragalus membranaceus induced by origin and their bioactivity. Foods, 2021, 10, 1755.

Wen Lingrong, Zhou Ting, Jiang Yueming, Gong Liang, Yang Bao*. Identification of prenylated phenolics in mulberry leaf and their neuroprotective activity, Phytomedicine, 2021, 90, 153641.

Zhou Ting, Guo Wei, Ren Shengchao, Li Yuming, Wu Jinming, Yang Bao*. Flavonoid glycosides and other bioactive compounds in Citrus reticulate ‘Chachi’ peel analysed by tandem mass spectrometry and their changes during storage. Carbohydrate Research, 2021, 510, 108462.

Sheng Zhili, Jiang Yueming, Liu Junmei, Yang Bao*. Analysis on flavonoids composition in Astragalus membranaceus and their antioxidant activity. Antioxidants, 2021, 10, 1852.

Sui Kiat Chang, Yueming Jiang, Bao Yang*. An update of prenylated phenolics: Food sources, chemistry and health benefits. Trends in Food Science & Technology, 2021, 108, 197-213.

Lingrong Wen, Dingding Shi, Ting Zhou, Jiaming Tu, Mingyang He, Yueming Jiang, Bao Yang*. Identification of two novel prenylated flavonoids in mulberry leaf and their bioactivities. Food Chemistry, 2020, 315, 126236.

Jiali Yang, Ting Zhou, Yueming Jiang, Bao Yang*. Substrate specificity change of a flavonoid prenyltransferase AhPT1 induced by metal ion. International Journal of Biological Macromolecules, 2020, 153, 264-275.

Dingding Shi, Jiali Yang, Yueming Jiang, Lingrong Wen*, Zhubin Wang, Bao Yang*. The antioxidant activity and neuroprotective mechanism of isoliquiritigenin. Free Radical Biology and Medicine, 2020, 152, 207-215.

Jiali Yang, Lingrong Wen, Yueming Jiang, Bao Yang*. Natural estrogen receptor modulators and their heterologous biosynthesis. Trends in Endocrinology and Metabolism, 2019, 30, 66-76. 

Bao Yang*, Huiling Liu, Jiali Yang, Vijai Kumar Gupta*, Yueming Jiang*. New insights on bioactivities and biosynthesis of flavonoid glycosides. Trends in Food Science and Technology, 2018, 79, 116-124.

Jiali Yang, Lingrong Wen, Yupeng Zhao, Yueming Jiang, Bao Yang*. Structure identification of an arabinogalacturonan in Citrus reticulata Blanco ‘Chachiensis’ peel. Food Hydrocolloids, 2018, 84, 481-488.

Juan Liu, Yupeng Zhao, Qixian Wu, Afiya John, Yueming Jiang, Jiali Yang, Huiling Liu, Bao Yang*. Structure characterisation of polysaccharides in vegetable “okra” and evaluation of hypoglycemic activity. Food Chemistry, 2018, 242, 211-216.

Hongxin Liu, Yu Wang, Xueying Guo, Luqiong Huo, Zhifang Xu, Weimin Zhang, Shengxiang Qiu, Bao Yang*, Haibo Tan. A bioinspired cascade sequence enables facile assembly of methanodibenzo[b,f][1,5]dioxocin flavonoid scaffold. Organic Letters, 2018, 20, 546-549.

Hongxin Liu, Luqiong Huo, Bao Yang, Yunfei Yuan, Weimin Zhang, Zhifang Xu, Shengxiang Qiu, Haibo Tan. Biomimetic-inspired syntheses of myrtucommuacetalone and myrtucommulone J. Organic Letters, 2017, 19, 4786-4789.

      Lingrong Wen, Yupeng Zhao, Yueming Jiang, Limei Yu, Xiaofang Zeng, Jiali Yang, Miaomiao Tian, Huiling Liu, Bao Yang*. Identification of a flavonoid C-glycoside as potent antioxidant. Free Radical Biology and Medicine, 2017, 110, 92-101.

Lingrong Wen, Yueming Jiang, Jiali Yang, Yupeng Zhao, Miaomiao Tian, Bao Yang*. Structure, bioactivity and synthesis of methylated flavonoids. Annals of the New York Academy of Sciences, 2017, 1398, 120-129.

 Lingrong Wen, Lijun You, Xiaoman Yang, Jiali Yang, Feng Chen, Yueming Jiang, Bao Yang*. Identification of phenolics in litchi and evaluation of anticancer cell proliferation activity and intracellular antioxidant activity. Free Radical Biology & Medicine, 2015, 84, 171-184.

 Qinqin Zhu, Yueming Jiang, Sen Lin, Lingrong Wen, Dan Wu, Mouming Zhao, Feng Chen, Yongxia Jia, Bao Yang*. Structural identification of (1→6)-α-D-glucan, a key responsible for the health benefits of longan, and evaluation of anticancer activity. Biomacromolecules, 2013, 14, 1999-2003.

 Xiaoman Yang, Yueming Jiang, Jiali Yang, Jirui He, Jian Sun, Feng Chen, Mingwei Zhang, Bao Yang*. Prenylated flavonoids, promising nutraceuticals with impressive health benefits. Trends in Food Science and Technology, 2015, 44, 

Bao Yang, Hongshun Yang, Feng Chen, Yanglin Hua, Yueming Jiang. Phytochemical analyses of Ziziphus jujuba Mill. var. spinosa seed by ultrahigh performance liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry. Analyst, 2013, 138, 6881-6888.

Lingrong Wen, Jirui He, Dan Wu, Yueming Jiang, K. Nagendra Prasad, Mouming Zhao, Sen Lin, Guoxiang Jiang, Wei Luo, Bao Yang*. Identification of sesquilignans in litchi (Litchi chinensis Sonn.) leaf and their anticancer activities. Journal of Functional Foods, 2014, 8, 26-34.

 Yunfei Yuan, Yan-Bo Wang, Yueming Jiang, K. Nagendra Prasad, Jiali Yang, Hongxia Qu, Ying Wang, Yongxia Jia, Hui Mo, Bao Yang*. Structure identification of a polysaccharide purified from Lycium barbarium fruit. International Journal of Biological Macromolecules, 2016, 82, 696-701.

Sen Lin, Jirui He, Yueming Jiang, Fuwang Wu, Hui Wang, Dan Wu, Jian Sun, Dandan Zhang, Hongxia Qu, Bao Yang*. Production of nigragillin and dihydrophaseic acid by biotransformation of litchi pericarp with Aspergillus awamori and their antioxidant activities. Journal of Functional Foods, 2014, 7, 278-286.

 Lingrong Wen, Dan Wu, Yueming Jiang, K. Nagendra Prasad, Sen Lin, Guoxiang Jiang, Jirui He, Mouming Zhao, Wei Luo, Bao Yang*. Identification of flavonoids in litchi (Litchi chinensis Sonn.) leaf and evaluation of anticancer activities. Journal of Functional Foods, 2014, 6, 555-563.

Bao Yang, K. Nagendra Prasad, Yueming Jiang. Structure identification of a polysaccharide purified from litchi (Litchi chinensis Sonn.) pulp. Carbohydrate Polymers, 2016, 137, 570-575.

Guoxiang Jiang, Sen Lin, Lingrong Wen, Yueming Jiang, Mouming Zhao, Feng Chen, K Nagendra Prasad, Xuewu Duan, Bao Yang*. Identification of a novel phenolic compound in litchi (Litchi chinensis Sonn.) pericarp and bioactivity evaluation. Food Chemistry, 2013, 136, 563-568.

Bao Yang, Feng Chen, Yanglin Hua, Shan-Shan Huang, Sen Lin, Lingrong Wen, Yueming Jiang. Prooxidant activities of quercetin, p-courmaric acid and their derivatives analysed by quantitative structure-activity relationship. Food Chemistry, 2012, 131, 508–512.

Guoxiang Jiang, Bao Yang*, Yueming Jiang, Rong Tsao, Haiyan Zhang, Feng Chen. Structural characteristics and antioxidant activities of oligosaccharides from longan fruit pericarp. Journal of Agricultural and Food Chemsitry, 2009, 57, 9293–9298.

Mouming Zhao*, Bao Yang*, Jinshui Wang, Yang Liu, Limei Yu, Yueming Jiang. Immunomodulatory and anticancer activities of flavonoids extracted from litchi (Litchi chinensis Sonn.) pericarp. International Immunopharmacology. 2007, 7, 162–166. 

Bao Yang, Yueming Jiang, John Shi, Feng Chen, Muhammad Ashraf. Extraction and pharmacological properties of bioactive compounds from longan (Dimocarpus longan Lour.) fruit – A review. Food Research International, 2011, 44, 1837–1842.


Grants

1. National Natural Science Foundation of China, Nos. 32071809, 31871851, 31671906, 30700557, 31071638, 30910103040, 31010103044, 31110103046, 2008.01-present, Principal Investigator.

2. National Key Research and Development Program of China, No. 2017YFD0401301,  Principal Investigator.

3. International foundation for Science (Sweden), No. F/4451-1, F/4451-2, Principal Investigator.

4. Key Program of Chinese Academy of Sciences, No. QYZDB-SSW-SMC018, Principal Investigator.

5. Outstanding Young Scholar Fund of Guangdong Province, No S2013050014131, Principal Investigator.