071005-微生物学
071010-生物化学与分子生物学

单细胞分析分选新方法

2010-09--2015-09   华中科技大学   博士
2006-09--2010-07   潍坊医学院   学士

   

2021-01~现在, 中国科学院青岛生物能源与过程研究所, 副研究员
2018-04~2020-12,中国科学院青岛生物能源与过程研究所, 助理研究员
2015-12~2018-03,中国科学院青岛生物能源与过程研究所, 博士后

   

[1] 马波, 刁志钿, 王喜先, 徐腾, 徐健. 基于光热效应进行微量液滴操控的微流控芯片及方法. CN: CN112871227A, 2021-06-01.

[2] 马波, 徐健, 王喜先, 任立辉, 籍月彤. 一种拉曼激活液滴分选系统和方法. CN: CN109706053B, 2021-04-23.

   

[1] Wang, Xixian, Xin, Yi, Ren, Lihui, Sun, Zheng, Zhu, Pengfei, Ji, Yuetong, Li, Chunyu, Xu, Jian, Ma, Bo. Positive dielectrophoresis-based Raman-activated droplet sorting for culture-free and label-free screening of enzyme function in vivo. SCIENCE ADVANCES[J]. 2020, 6(32): https://www.webofscience.com/wos/woscc/full-record/WOS:000560452300026.
[2] Ma, Peng, Wang, Shanshan, Guan, Ruixue, Hu, Liang, Wang, Xixian, Ge, Anle, Zhu, Jinchi, Du, Wei, Liu, BiFeng. An integrated microfluidic device for studying controllable gas embolism induced cellular responses. TALANTA[J]. 2020, 208: http://dx.doi.org/10.1016/j.talanta.2019.120484.
[3] Wang, Yu, Wang, Xixian, Ge, Anle, Hu, Liang, Du, Wei, Liu, BiFeng. A dual-stimulation strategy in a micro-chip for the investigation of mechanical associative learning behavior of C. elegans. TALANTA[J]. 2020, 215: http://dx.doi.org/10.1016/j.talanta.2020.120900.
[4] Ge, Anle, Wang, Xixian, Ge, Minghai, Hu, Liang, Feng, Xiaojun, Du, Wei, Liu, BiFeng. Profile analysis of C-elegans rheotaxis behavior using a microfluidic device. LAB ON A CHIP[J]. 2019, 19(3): 475-483, http://dx.doi.org/10.1039/c8lc01087k.
[5] He, Yuehui, Wang, Xixian, Ma, Bo, Xu, Jian. Ramanome technology platform for label-free screening and sorting of microbial cell factories at single-cell resolution. BIOTECHNOLOGY ADVANCESnull. 2019, 37(6): http://dx.doi.org/10.1016/j.biotechadv.2019.04.010.
[6] Cui, Xiaonan, Ren, Lihui, Shan, Yufei, Wang, Xixian, Yang, Zhenlong, Li, Chunyu, Xu, Jian, Ma, Bo. Smartphone-based rapid quantification of viable bacteria by single-cell microdroplet turbidity imaging. ANALYST[J]. 2018, 143(14): 3309-3316, https://www.webofscience.com/wos/woscc/full-record/WOS:000438056400006.
[7] Hu, Liang, Ge, Anle, Wang, Xixian, Wang, Shanshan, Yue, Xinpei, Wang, Jie, Feng, Xiaojun, Du, Wei, Liu, BiFeng. Real-time monitoring of immune responses under pathogen invasion and drug interference by integrated microfluidic device coupled with worm-based biosensor. BIOSENSORS & BIOELECTRONICS[J]. 2018, 110: 233-238, http://dx.doi.org/10.1016/j.bios.2018.03.058.
[8] Wang, Xixian, Ge, Anle, Hu, Liang, Feng, Xiaojun, Du, Wei, Liu, BiFeng. A microfluidic microfilter chip driven by electrotaxis and fluid flow for size-dependent C-elegans sorting with high purity and efficiency. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 260: 311-319, http://dx.doi.org/10.1016/j.snb.2018.01.077.
[9] Liang Hu, Anle Ge, Xixian Wang, Shanshan Wang, Xinpei Yue, Jie Wang, Xiaojun Feng, Wei Du, BiFeng Liu. Real-time monitoring of immune responses under pathogen invasion and drug interference by integrated microfluidic device coupled with worm-based biosensor. BIOSENSORS AND BIOELECTRONICS. 2018, 110: 233-238, http://dx.doi.org/10.1016/j.bios.2018.03.058.
[10] Ge, Anle, Hu, Liang, Wang, Xixian, Zhu, Jinchi, Feng, Xiaojun, Du, Wei, Liu, BiFeng. Logarithmic bacterial gradient chip for analyzing the effects of dietary restriction on C. elegans growth. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 255: 735-744, http://dx.doi.org/10.1016/j.snb.2017.08.088.
[11] Wang, Xixian, Ren, Lihui, Su, Yetian, Ji, Yuetong, Liu, Yaoping, Li, Chunyu, Li, Xunrong, Zhang, Yi, Wang, Wei, Hu, Qiang, Han, Danxiang, Xu, Jian, Ma, Bo. Raman-Activated Droplet Sorting (RADS) for Label-Free High-Throughput Screening of Microalgal Single-Cells. ANALYTICAL CHEMISTRY[J]. 2017, 89(22): 12569-12577, http://dx.doi.org/10.1021/acs.analchem.7b03884.
[12] Wang, Xixian, Ge, Anle, Hu, Liang, Feng, Xiaojun, Du, Wei, Liu, BiFeng. A novel on-chip immobilization strategy for imaging analysis of neuronal response to gas cues in C. elegans. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2017, 244: 1152-1159, http://dx.doi.org/10.1016/j.snb.2017.01.083.
[13] Wang, Xixian, Hu, Rui, Ge, Anle, Hu, Liang, Wang, Shanshan, Feng, Xiaojun, Du, Wei, Liu, BiFeng. Highly efficient microfluidic sorting device for synchronizing developmental stages of C. elegans based on deflecting electrotaxis. LAB ON A CHIP[J]. 2015, 15(11): 2513-2521, http://www.irgrid.ac.cn/handle/1471x/981936.

   

（ 1 ） 基于单细胞拉曼光谱的高通量表型检测与分选方法学研究, 主持, 国家级, 2020-01--2023-12
（ 2 ） 单细胞水平高产虾青素雨生红球藻高通量筛选新方法研究, 主持, 国家级, 2017-01--2019-12
（ 3 ） 基于单细胞拉曼光谱的合成生物表型测试与分选关键技术开发, 主持, 市地级, 2020-01--2021-12