General
Our group interest is natural product chemistry, mainly about the natural compounds and its activities from traditional Chinese medicinal plants.

Research Areas

natural product chemistry, plant chemistry

Education

1989.9–1992.6, Lanzhou University,  Ph.D., Organic Chemistry

1986.9–1989.6, Lanzhou University, M.Sc., Organic Chemistry

       1982.9–1986.7, Chengdu University of Science & Technology (Sichuan University), B.Sc., Physical Chemistry


Experience

   
Work Experience

2015.12-               Chengdu Institute of Biology,  professor

2001.9-2015.12.   HOYA Vision Care Company, Senior Researcher

1999.4-2001.8     Chengdu Institute of Biology, Associate professor

1998.1-1999.4     The University of Wisconsin-Madison, Research Associate

1995.4-1997.12   Chengdu Institute of Biology, Associate professor and depute head of Phytochemistry Division

1994.4–1995.4    Toray Basic Research Institute, Research Associate

1992.7–1994.12  Chengdu Institute of Biology, Assistant professor


Publications

    Up to now, 126 research papers were published. 30 Patents were applied and 20 patents were registered.

Papers

1.     Fu Li, Bao-Wen Du, Dan-Feng Lu, Wen-Xuan Wu, Kanjana Wongkrajang, Lun Wang, Wen-Chen Pu, Chang-Lu Liu, Han-Wei Liu, Ming-Kui Wang & Fei Wang. Flavonoid glycosides isolated from Epimedium brevicornum and their estrogen biosynthesis-promoting effects. Scientific Reports, 2017. DOI:10.1038/s41598-017-08203-7

2.     Wang, Lun, Jiang, Xi-Lan, Zhang, Wen-Ming, Li, Fu, Khan, Ashfaq-Ahmad, Liu, Xin, Yu, Kai, Wang, Ming-Kui. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogon japonicus. PHYTOCHEMISTRY, 2017, 136, 125-132.

3.     Gu, Xin-Yue, Wu, Zhou-Wei, Wang, Lun, Li, Fu, Chen, Bin, Yu, Kai, Wang, Ming-Kui. C-21 steroidal glycosides and oligosaccharides from the root bark of Periploca sepium. FITOTERAPIA, 2017, 118: 6-12.

4.     Li, Fu, Yang, Fumei, Liu, Xin, Wang, Lun, Chen, Bin, Li, Lianhong, Wang, Mingkui. Cucurbitane glycosides from the fruit of Siraitia grosvenori and their effects on glucose uptake in human HepG2 cells in vitro. FOOD CHEMISTRY, 2017, 228: 567-573.

5.     Jiayou Sun, Lun Wang, Mingkui Wang, Zhizhong Wang & Fu Li. Two new polyacetylene glycosides from the roots of Codonopsis tangshen Oliv. Natural Product Research, 2016, 30(20): 2338-2343.

6.     Xiao-Long Zhang, Ashfaq-Ahmad Khan, Lun Wang, Kai Yu, Fu Li, Ming-Kui Wang. Four new phorbol diesters from Croton tiglium and their cytotoxic activities. Phytochemistry Letters, 2016, 16: 82–86.

7.     Chunyan Yang, Fu Li, Lun Wang, Wenjun He, Bin Chen, and Mingkui Wang*. Phenolic Compounds From Glycyrrhiza Uralensis And Their Radical-Scavenging Activity, Chemistry of Natural Compounds, 2016, 52(3): 490-491.

8.     Lun Wang, Fu Li, Xin Liu, Bin Chen, Kai Yu, Ming-Kui Wang. Meroterpenoids and a Naphthoquinone from Arnebia euchroma and Their Cytotoxic Activity. Planta Medica. 2015, 81(4):320-6. (DOI: 10.1055/s-0035-1545693) (Impact Factor: 2.35)

9.     Cao, Mei-Na; Zhou, Yu-Bo; Gao, An-Hui; Cao, Jia-Yi; Gao, Li-Xin; Sheng, Li; Xu, Lei; Su, Ming-Bo; Cao, Xian-Chao; Han, Meng-meng; Wang, Ming-Kui; Li, Jia, Curcusone D, a novel ubiquitin-proteasome pathway inhibitor via ROS-induced DUB inhibition, is synergistic with bortezomib against multiple myeloma cell growth. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, DIO10.1016/j.bbagen.2014.02.006.

10. Lun Wang, Fu Li, Chun-Yan Yang, Ashfaq-Ahmad Khan, Xin Liu, Ming-Kui Wang. Neolignans, lignans and glycoside from the fruits of Melia toosendan. Fitoterapia, 2014, 99: 92-98.

11. Wenjun He, Chunyan Yang, Mingkui Wang, Fu Li. A novel phenolic acid from the fruits of Rosa Soulieana. Natural Product Research, 2014, 28(15): 1127-1133. 

12. Chunyan Yang, Fu Li, Baowen Du, Bin Chen, Fei Wang, Mingkui Wang. Isolation and Characterization of New Phenolic Compounds with Estrogen Biosynthesis- Inhibiting and Antioxidation Activities from Broussonetia papyrifera Leaves. PLoS ONE, 2014, 9(4): e94198. doi:10.1371/journal.pone.0094198.

13. Fu Li, Hong-Mei Pan, Xin Liu, Bin Chen, Ya-Xiong Tang, Xing-Jun Xi, Mingkui Wang. New phenanthrene glycosides from Dendrobium denneanum and their cytotoxic activity. Phytochemistry Letters, 2013, 6: 640–644.

14. Lun Wang, Jing Wang, Fu Li, Xin Liu, Bin Chen, Ya-Xiong Tang, Mingkui Wang. Cytotoxic Sesquiterpene Lactones from Aerial Parts of Xanthium sibiricum. Planta Medica, 2013, 79(8): 661-665.

15. Xiao-Long Zhang, Lun Wang, Xin Liu, Fu Li, Kai Yu and Ming-Kui Wang. Cytotoxic Phorbol Esters of Croton tiglium. Journal of Natural Products, 2013, 76(5): 858-864.

16. Chunyan Yang, Fu Li, Xiaolong Zhang, Lun Wang, Zhiqiong Zhou and Mingkui Wang. Phenolic antioxidants from Rosa soulieana flowers. Natural Product Research, 2013, 27(21): 2055-2058.

17. Cheng Zhi, Wang Lun, Li Fu, Wang Ming-Kui. A New Thiazinedione Glycoside from the Fruit of Xanthium sibiricum. Chemistry of Natural Compounds, 2013, 49(5): 977-979.



Students

已指导学生

程智  硕士研究生  077901-药物化学  

瞿庆喜  硕士研究生  100701-药物化学  

钟汉庭  硕士研究生  077901-药物化学  

李甫  博士研究生  100701-药物化学  

潘红玫  硕士研究生  077901-药物化学  

张小龙  博士研究生  100701-药物化学  

贺文君  硕士研究生  077901-药物化学  

杨春艳  博士研究生  100701-药物化学  

吴文轩  硕士研究生  085235-制药工程  

王伦  博士研究生  100701-药物化学  

蒋锡兰  硕士研究生  078001-药物化学  

辜新月  硕士研究生  085235-制药工程  

吴周维  硕士研究生  085238-生物工程  

伍丙兰  硕士研究生  078001-药物化学  

现指导学生

王玉伟  硕士研究生  085238-生物工程  

杨凡  博士研究生  100701-药物化学  

侯晓余  硕士研究生  078001-药物化学  

普行艺  博士研究生  100701-药物化学  

张霞  博士研究生  100701-药物化学  

杨彬彬  硕士研究生  085238-生物工程  

蒋锡兰  博士研究生  100701-药物化学