基本信息
王怀雨  男  硕导  中国科学院深圳先进技术研究院
电子邮件: hy.wang1@siat.ac.cn
通信地址: 深圳市南山区西丽深圳大学城学苑大道1068号
邮政编码: 518055

研究领域

骨科植入材料

纳米生物材料

表面功能化修饰


招生信息

招收生物材料及相关领域研究生

招生专业
083100-生物医学工程
招生方向
生物材料
表面改性
生物学评价

教育背景

2004-09--2009-07   中国科学院理化技术研究所   博士学位
2000-09--2004-07   北京大学医学部   学士学位

工作经历

2017-01--至今       中国科学院深圳先进技术研究院 研究员

2013-08--2016-12 中国科学院深圳先进技术研究院 副研究员

2012-08--2013-08 香港城市大学 Postdoctoral Fellow
2009-06--2012-08 香港城市大学 Senior Research Associate
2007-03--2009-03 香港城市大学 Research Assistant


专利

1. 喻学锋,邵俊东,王怀雨。一种聚合物包裹的黑磷及其制备方法。专利号:ZL 201610729312.5

2. 喻学锋,赵岳涛,王怀雨。一种经芳香族化合物修饰的黑磷及其制备方法与应用。专利号: ZL 201610707744.6

3. 喻学锋, 孙正博,王怀雨。一种黑磷纳米片及其制备方法与应用。专利号:ZL 201610680032.X

4. 王怀雨,赵岳涛,喻学锋。经钛配体修饰的黑磷及其制备方法与应用。专利号: ZL 201510956724.8

5. 王喆,叶忱,潘浩波,王怀雨一种麦麸微晶纤维素及其制备方法。专利号:201510280359.3

6. 张维, 王怀雨, 季君晖。采用磁控溅射技术制备医用高分子材料的方法。专利号: ZL 201110190842.4

7. Jian Lu, Huaiyu Wang. Application of the Newly Developed Technology in Stainless Steel for Biomedical Implant. Patent No.: US 9579772 B2




发表论文

1.       #Guomin Wang, #Hongqing Feng, Liangsheng Hu, Weihong Jin, Qi Hao, Ang Gao, Xiang Peng, Wan Li, Kwok-Yin Wong, *Huaiyu Wang(通讯作者), *Zhou Li, *Paul K. Chu. An Antibacterial Platform Based on Capacitive Carbon-Doped TiO2 Nanotubes after Charging with Direct/Alternating Currents. Nature Communications, 9, 2055, 2018.  IF: 12.124

2.       Jundong Shao, Changshun Ruan, Hanhan Xie, Zhibin Li, *Huaiyu Wang(通讯作者), Paul K. Chu, *Xuefeng Yu. Black-Phosphorus-Incorporated Hydrogel as a Sprayable, Biodegradable, and Bactericidal Platform for Postsurgical Treatment of Cancer. Advanced Science, 5, 1700848, 2018.  IF: 9.034

3.       Huaiyu Wang, *Xuefeng Yu, Few-Layered Black Phosphorus: From Fabrication and Customization to Biomedical Applications. Small, 14, 1702830, 2018.  IF: 8.643

4.       Jundong Shao, Hanhan Xie, *Huaiyu Wang(通讯作者), Wenhua Zhou, Qian Luo, *Xuefeng Yu, *Paul K. Chu. 2D Material-Based Nanofibrous Membrane for Photothermal Cancer Therapy. ACS Applied Materials & Interfaces, 10, pp 1155-1163, 2018.  IF: 7.504

5.       Ang Gao, Ruiqiang Hang, Wan Li, Wei Zhang, Penghui Li, Guomin Wang, Long Bai, Xuefeng Yu, *Huaiyu Wang(通讯作者), *Liping Tong, *Paul K. Chu. Linker-free Covalent Immobilization of Heparin, SDF-1α, and CD47 on PTFE Surface by Plasma Treatment for Antithrombogenicity, Endothelialization and Anti-Inflammation. Biomaterials, 140, pp 201-211, 2017.  IF: 8.402

6.       Zhibin Li, Jundong Shao, Qian Luo, *Xuefeng Yu, Hanhan Xie, Haidi Fu, Siying Tang, *Huaiyu Wang(通讯作者), Guangli Han, *Paul K. Chu. Cell-Borne 2D Nanomaterials for Efficient Cancer Targeting and Photothermal Therapy. Biomaterials, 133, pp 37-48, 2017.  IF: 8.402

7.       Zhengbo Sun, Yuetao Zhao, Zhibin Li, Haodong Cui, Yayan Zhou, Weihao Li, Wei Tao, *Han Zhang, *Huaiyu Wang(通讯作者), Paul K. Chu, *Xuefeng Yu. TiL4-Coordinated Black Phosphorus Quantum Dots as an Efficient Contrast Agent for In Vivo Photoacoustic Imaging of Cancer. Small, 13, 1602896, 2017.  IF: 8.643

8.       Yuetao Zhao, *Huaiyu Wang(通讯作者), Hao Huang, Quanlan Xiao, Yanhua Xu, Zhinan Guo, Hanhan Xie, Jundong Shao, Zhengbo Sun, Weijia Han, *Xuefeng Yu, Penghui Li, *Paul K. Chu. Surface Coordination of Black Phosphorus for Robust Air and Water Stability. Angewandte Chemie International Edition, 55, pp 5003-5007, 2016.  IF: 11.994

9.       Yuetao Zhao, Liping Tong, Yong Li, Haobo Pan, Wei Zhang, Min Guan, Weihao Li, Yixin Chen, Qing Li, Zhongjun Li, *Huaiyu Wang(通讯作者), *Xuefeng Yu, *Paul K. Chu. Lactose-Functionalized Gold Nanorods for Sensitive and Rapid Serological Diagnosis of Cancer. ACS Applied Materials & Interfaces, 8, pp 5813-5820, 2016.  IF: 7.504

10.   #Zhibin Li, #Siying Tang, #Beike Wang, Yong Li, Hao Huang, *Huaiyu Wang(通讯作者), Penghui Li, *Chengzhang Li, *Paul K. Chu, Xuefeng Yu. Metabolizable Small Gold Nanorods: Size-dependent Cytotoxicity, Cell Uptake and In Vivo Biodistribution. ACS Biomaterials Science & Engineering, 2, pp 789-797, 2016.  IF: 3.234

11.   #Liping Tong, #Wenhua Zhou, Yuetao Zhao, Xuefeng Yu, *Huaiyu Wang(通讯作者), *Paul K. Chu. Enhanced Cytocompatibility and Reduced Genotoxicity of Polydimethylsiloxane Modified by Plasma Immersion Ion Implantation. Colloids and Surfaces B: Biointerfaces, 148, pp 139-146, 2016.  IF: 3.887

12.   Changshun Ruan, Yang Hu, Lixin Jiang, Qingqing Cai, Haobo Pan, *Huaiyu Wang (通讯作者). Tunable Degradation of Piperazine-Based Polyurethane Ureas. Journal of Applied Polymer Science, 131, 40527, 2014.  IF: 1.86

13.   #Shenglin Mei, #Huaiyu Wang (共同第一作者), Wei Wang, Liping Tong, Haobo Pan, Changshun Ruan, Qianli Ma, Mengyuan Liu, Huiling Yang, Liang Zhang, Yicheng Cheng, *Yumei Zhang, *Lingzhou Zhao, *Paul K. Chu. Antibacterial Effects and Biocompatibility of Titanium Surfaces with Graded Silver Incorporation in Titania Nanotubes. Biomaterials, 35, pp 4255-4265, 2014.  IF: 8.402

14.   Huaiyu Wang, Dixon T. K. Kwok, Ming Xu, Haigang Shi, Zhengwei Wu, Wei Zhang, *Paul K. Chu. Tailoring of Mesenchymal Stem Cells Behavior on Plasma-Modified Polytetrafluoroethylene. Advanced Materials, 24, pp 3315-3324, 2012.  IF: 19.791

15.   Huaiyu Wang, *Ming Xu, Zhengwei Wu, Wei Zhang, Junhui Ji, *Paul K. Chu. Biodegradable Poly(Butylene Succinate) Modified by Gas Plasmas and Their In Vitro Functions as Bone Implants. ACS Applied Materials & Interfaces, 4, pp 4380-4386, 2012.  IF: 7.504

16.   Huaiyu Wang, Ming Xu, Wei Zhang, Dixon T. K. Kwok, Jiang Jiang, Zhengwei Wu, *Paul K. Chu. Mechanical and Biological Characteristics of Diamond-Like Carbon Coated Poly Aryl-Ether-Ether-Ketone. Biomaterials, 31, pp 8181-8187, 2010.  IF: 8.402

17.   Huaiyu Wang, Dixon T. K. Kwok, Wei Wang, Zhengwei Wu, Liping Tong, Yumei Zhang, *Paul K. Chu. Osteoblast Behavior on Polytetrafluoroethylene Modified by Long Pulse, High Frequency Oxygen Plasma Immersion Ion Implantation. Biomaterials, 31, pp 413-419, 2010.  IF: 8.402

18.   Huaiyu Wang, Junhui Ji, Wei Zhang, Wei Wang, Yihe Zhang, Zhengwei Wu, Yumei Zhang, *Paul K. Chu. Rat Calvaria Osteoblast Behavior and Antibacterial Properties of O2 and N2 Plasma-Implanted Biodegradable Poly(Butylene Succinate). Acta Biomaterialia, 6, pp 154-159, 2010.  IF: 6.319

19.   Huaiyu Wang, Junhui Ji, Wei Zhang, Yihe Zhang, Jiang Jiang, Zhengwei Wu, Shihao Pu, *Paul K. Chu. Biocompatibility and Bioactivity of Plasma-Treated Biodegradable Poly(Butylene Succinate). Acta Biomaterialia, 5, pp 279-287, 2009.  IF: 6.319



发表论文
(1) 2D Material-Based Nanofibrous Membrane for Photothermal Cancer Therapy, ACS Applied Materials & Interfaces, 2018, 通讯作者
(2) Few-Layered Black Phosphorus: From Fabrication and Customization to Biomedical Applications, Small, 2018, 第 1 作者
(3) Black-Phosphorus-Incorporated Hydrogel as a Sprayable, Biodegradable, and Bactericidal Platform for Postsurgical Treatment of Cancer, Advanced Science, 2018, 通讯作者
(4) An Antibacterial Platform Based on Capacitive Carbon-Doped TiO2 Nanotubes after Charging with Direct/Alternating Currents, Nature Communications, 2018, 通讯作者
(5) TiL4-Coordinated Black Phosphorus Quantum Dots as an Efficient Contrast Agent for In Vivo Photoacoustic Imaging of Cancer, Small, 2017, 通讯作者
(6) Cell-Borne 2D Nanomaterials for Efficient Cancer Targeting and Photothermal Therapy, Biomaterials, 2017, 通讯作者
(7) Linker-free Covalent Immobilization of Heparin, SDF-1α, and CD47 on PTFE Surface by Plasma Treatment for Antithrombogenicity, Endothelialization and Anti-Inflammation, Biomaterials, 2017, 通讯作者
(8) Enhanced Cytocompatibility and Reduced Genotoxicity of Polydimethylsiloxane Modified by Plasma Immersion Ion Implantation, Colloids and Surfaces B: Biointerfaces, 2016, 通讯作者
(9) Metabolizable Small Gold Nanorods: Size-dependent Cytotoxicity, Cell Uptake and In Vivo Biodistribution, ACS Biomaterials Science & Engineering, 2016, 通讯作者
(10) Lactose-Functionalized Gold Nanorods for Sensitive and Rapid Serological Diagnosis of Cancer, ACS Applied Materials & Interfaces, 2016, 通讯作者
(11) Surface Coordination of Black Phosphorus for Robust Air and Water Stability., Angewandte Chemie International Edition, 2016, 通讯作者
(12) Antibacterial effects and biocompatibility of titanium surfaces with graded silver incorporation in titania nanotubes, Biomaterials, 2014, 第 2 作者
(13) Study on the tunable degradation of piperazine-based polyurethane ureas, Journal of Applied Polymer Science, 2014, 通讯作者
(14) Tailoring of mesenchymal stem cells behavior on plasma-modified polytetrafluoroethylene, Advanced Materials, 2012, 第 1 作者
(15) Biodegradable poly(butylene succinate) modified by gas plasmas and their in vitro functions as bone implants, ACS Applied Materials and Interfaces, 2012, 第 1 作者
(16) Mechanical and biological characteristics of diamond-like carbon coated poly aryl-ether-ether-ketone, Biomaterials, 2010, 第 1 作者
(17) Osteoblast behavior on polytetrafluoroethylene modified by long pulse, high frequency oxygen plasma immersion ion implantation, Biomaterials, 2010, 第 1 作者
(18) Rat calvaria osteoblast behavior and antibacterial properties of O2 and N2 plasma-implanted biodegradable poly(butylene succinate), Acta Biomaterialia, 2010, 第 1 作者
(19) Biocompatibility and bioactivity of plasma-treated biodegradable poly(butylene succinate), Acta Biomaterialia, 2009, 第 1 作者
书籍章节

Characterization of biomaterials, Chapter 4: Surface characterization of biomaterials, Elsevier, 2013-07

获批项目

  1. 中国科学院STS区域重点项目,2018.01-2019.12,200万,主持,在研
  2. 中国科学院青年创新促进会会员,2017.01-2020.12, 80万,主持在研
  3. 兴发集团二维黑磷项目,2016.11-2021.10,2500万,参与(2/2),在研;
  4. 深圳市基础研究(学科布局),2016.06-2019.05,200万,主持,在研;
  5. 广东省特支计划青年拔尖人才,2016.06-2019.0530万,主持在研
  6. 深圳市孔雀团队,2016.01-2020.12, 1500万,参与(3/4),在研;
  7. 国家自然科学基金青年项目,2016.01-2018.1224万主持在研
  8. 深圳市基础研究(自由探索),2015.10-2017.0950万,主持在研
  9. 国家自然科学基金面上项目,2015.01-2016.1230万主持已结题


荣誉奖励

广东省科技创新青年拔尖人才;

深圳市海外高层次“孔雀计划”B类人才;

中国科学院青年促进会会员