基本信息
王浩 男 博导 国家纳米科学中心
电子邮件:wanghao@nanoctr.cn
通信地址:北京市海淀区中关村北一条11号
邮政编码:100190
部门/实验室:纳米生物效应与安全性研究室

研究领域

纳米生物材料的设计与合成
微流芯片用于纳米材料的初筛和癌症的体外诊断
癌症的体外、体内早期诊断纳米技术


教育背景

2000-09--2005-09 南开大学 博士
1996-09--2000-06 南开大学 本科
学历
博士研究生
学位

博士

工作经历

   
工作简历
2011-09--今 国家纳米科学中心 研究员
2007-08--2011-08 美国加州大学洛杉矶分校 博士后
2005-09--2007-06 德国维尔茨堡大学 博士后

教授课程

   

专利与奖励

   
奖励信息
(1) 中科院百人计划,院级级,2011
专利成果
(1) A Supramolecular Approach for Preparation of Size-Controllable Nanoparticles,发明,2012,第2作者,专利号:WO/2010/099466
(2) 3D Nanostructured Substrates for Highly Efficient Capture of Circulating Tumor Cells (CTCs),发明,2012,第3作者,专利号:WO/2010/108003
(3) 一种组织工程界面修饰材料、其修饰方法及应用,发明,2014,第1作者,专利号:201410095314.4
(4) 一种具有压致变色性质的双芘类化合物、制备方法及其应用,发明,2014,第1作者,专利号:201410147961.5
(5) 一种具有抗肿瘤活性的多肽聚合物及其制备方法和应用,发明,2014,第1作者,专利号:201410160139.2
(6) 一种靶向光声造影剂的制备及其体内细菌感染检测应用,发明,2014,第1作者,专利号:201410213818.1
(7) 一种金磷炔化合物、其制备方法及用途,发明,2013,第1作者,专利号:201310439357.5
(8) 一种双芘类化合物及其荧光纳米聚集体和应用,发明,2013,第1作者,专利号:201310294411.1

出版信息

   
发表论文
(1) A pH-responsive natural cyclopeptide RA-V drug formulation for improved breast cancer therapy,J. Mater. Chem. B,2015,通讯作者
(2) Pathological Condition Driven Construction of Supramolecular Nano-Assemblies for Bacterial Infection Detection,Adv. Mater.,2015,通讯作者
(3) Supramolecular Nanosubstrate-Mediated Delivery for Reprogramming and Transdifferentiation of Mammalian Cells,Small,2015,通讯作者
(4) Recent Advances in Near-Infrared Absorption Nanomaterials as Photoacoustic Contrast Agents for Biomedical Imaging,Chin. J. Chem. ,2015,通讯作者
(5) Bis-Pyrene Based Reversibly Multi-Responsive Fluorescence Switches,J. Mater. Chem. C,2015,通讯作者
(6) An Adaptive Biointerface from Self-Assembled Functional Peptides for Tissue Engineering,Adv. Mater.,2015,通讯作者
(7) Self-assembly of Cytotoxic Peptide Conjugated Poly(β-amino ester)s for Synergistic Cancer Chemotherapy,J. Mater. Chem. B,2015,通讯作者
(8) Unprecedentedly High Tissue Penetration Capability of Co-Assembled Nanosystems for Two-Photon Fluorescence Imaging In Vivo,Adv. Opt. Mater.,2015,通讯作者
(9) Self-Assembled Autophagy-Inducing Polymeric Nanoparticles for Breast Cancer Interference in Vivo,Adv. Mater.,2015,通讯作者
(10) Synthesis of self-reporting polymeric nanoparticles for in situ monitoring of endocytic microenvironmental pH,Chem. Commun.,2015,通讯作者
(11) A pH-responsive natural cyclopeptide RA-V drug formulation for improved breast cancer therapy,J. Mater. Chem. B,2015,通讯作者
(12) Smart Supramolecular Nanosystems for Bioimaging and Drug Delivery,Chin. J. Chem.,2014,通讯作者
(13) Nano-Confined Squaraine Dye Assemblies: New Photoacoustic and Near-Infrared Fluorescence Dual-Modular Imaging Probes in Vivo,Bioconjugate Chem.,2014,通讯作者
(14) Rapid Screening of Peptide Probes through In Situ Single-Bead Sequencing Microarray,Anal. Chem. ,2014,通讯作者
(15) Molecular Recognition Enables Nanosubstrate-Mediated Delivery of Gene-Encapsulated Nanoparticles with High Efficiency,ACS Nano,2014,通讯作者
(16) Supramolecular Adducts of Squaraine and Protein for Noninvasive Tumor Imaging and Photothermal Therapy In Vivo,Biomaterials,2014,通讯作者
(17) Core-Shell Supramolecular Gelatin Nanoparticles for Adaptive and “On-Demand” Bacterial Infection Treatment,ACS Nano,2014,通讯作者
(18) Bis-Pyrene Carbocations for Chromogenic and Fluorogenic Dual-Detection of Fluoride Anion In-Situ,Tetrahedron,2014,通讯作者
(19) Bis-Pyrene-Based Supramolecular Aggregates with Reversibly Mechanochromic and Vapochromic Responsiveness,J. Mater. Chem. C,2014,通讯作者
(20) Molecular Structural Transformation Regulated Dynamic Disordering of Supramolecular Vesicles as pH-Responsive Drug Release Systems,J. Controlled Release,2014,通讯作者
(21) Dynamic Disordering of Liposomal Cocktails and the Spatio-Temporal Favorable Release of Cargoes to Circumvent Drug Resistance,Biomaterials,2014,通讯作者
(22) A Photoacoustic Approach for Monitoring the Drug Release of pH-sensitive Poly(β-amino ester)s,J. Mater. Chem. B,2014,通讯作者
(23) Synthesis and Molecular Recognition Studies on Small-Molecule Inhibitors for Thioredoxin Reductase ,J. Med. Chem.,2014,通讯作者
(24) One-pot Synthesis of pH-sensitive Poly(RGD-co-β-amino ester)s for Targeted Intracellular Drug Delivery,Polym. Chem. ,2014,通讯作者
(25) Host-Guest Supramolecular Nanosystems for Cancer Diagnostics and Therapeutics,Adv. Mater. ,2013,通讯作者
(26) Magneto-Controllable Capture and Release of Cancer Cells by Using a Micropillar Device Decorated with Graphite Oxide-Coated Magnetic Nanoparticles,Small,2013,第5作者
(27) A Non-Contact Strategy for Controlled Enrichment, Manipulation and Separation of Carbon Nanotubes by Surface Acoustic Waves,Appl. Phys. Lett.,2013,通讯作者
(28) On-Demand Drug Release System for In Vivo Cancer Treatment through Self-Assembled Magnetic Nanoparticles,Angew. Chem. Int. Ed,2013,第5作者
(29) Enzyme-Coated Mesoporous Silica Nanoparticles as Efficient Anti-bacterial Agents In Vivo,Adv. Healthcare Mater,2013,通讯作者
(30) Recent Advances in Biocompatible Supramolecular Assemblies for Biomolecular Detection and Delivery,Chin. Chem. Lett.,2013,通讯作者
(31) Supramolecular Gelatin Nanoparticles as Matrix Metalloproteinases Responsive Cancer Cell Imaging Probes,Chem. Commun,2013,通讯作者
(32) Delivery of Intact Transcription Factor Using Self-Assembled Supramolecular Nanoparticles,Angew Chem. Int. Ed.,2011,通讯作者
(33) A Rapid Pathway Toward a Superb Gene Delivery System: Programming Structural and Functional Diversity into a Supramolecular Nanoparticle Library,ACS Nano,2010,第1作者
(34) Photothermal Effects of Supramolecularly Assembled Gold Nanoparticles for the Targeted Treatment of Cancer Cells,Angew. Chem. Int. Ed.,2010,第4作者
(35) A Small Library of DNA-Encapsulated Supramolecular Nanoparticles for Targeted Gene Delivery,Chem. Commun.,2010,通讯作者
(36) A Supramolecular Approach for Preparation of Size-Controllable Nanoparticles,Angew Chem. Int. Ed.,2009,第1作者
(37) Perylene Bisimide J-Aggregates with Absorption Maxima in the NIR,Chem. Commun.,2008,第1作者
(38) Supramolecular Construction of Fluorescence J-Aggregates Based on Hydrogen-Bonded Perylene Dyes,Angew. Chem. Int. Ed.,2007,第2作者
发表著作
(1) 超分子纳米颗粒在癌症诊断和治疗中的应用研究,Supramolecular Nanoparticles for Molecular Diagnostics and Therapeutics,John Wiley Sons Ltd,2012-06,第3作者

科研活动

   
参与会议
   

指导学生

现指导学生

乔圣林  硕士研究生  070304-物理化学  

安红维  博士研究生  070304-物理化学  

王羿  博士研究生  0703J1-纳米科学与技术  

林耀新  博士研究生  070304-物理化学  

马洋  硕士研究生  085204-材料工程  

尚宁宁  硕士研究生  070304-物理化学  

外国留学生
Yeshan J Rajapaksha

王浩课题组主页

http://www.nanoctr.cn/wanghao