基本信息

隋南  博导  中国科学院心理研究所
电子邮件: suin@psych.ac.cn
通信地址: 北京市朝阳区林萃路16号院
邮政编码: 100101

研究领域

以小鸡、啮齿类动物及树鼩为主要动物行为模型,通过内窥成像、光遗传学等神经生物学手段,研究药物成瘾的脑机制。并拓展到行为成瘾与药物成瘾患者行为决策认知机制的研究,胚胎期成瘾药物暴露对子代神经发育及成瘾易感性的影响,以及对抑郁症神经机制的研究和新型抗抑郁药物的筛选。

具体方向:
1.药物成瘾的DNA甲基化机制。
2.胚胎期成瘾药物暴露影响子代学习记忆能力及成瘾易感性的GABA机制。
3.近灵长类动物(树鼩)药物成瘾模型的创建及成瘾行为神经生物学机制的研究。
4.树鼩抑郁症机制的研究及新型抗抑郁药物的筛选。
5.行为成瘾与药物成瘾患者行为决策认知机制的研究。

教育背景

2007-01--2007-12   瑞士洛桑联邦理工学院   访问学者
2003-01--2003-04   Michigan Univerisity, Mayo医学院,美国   访问学者
1998-07--1998-10   Dept. of Biopsychology, UNED,西班牙   访问学者
1995-10--1996-10   Open University, 英国   访问学者

工作经历

   
工作简历
1998-05~2011-07,中国科学院心理研究所, 研究员,博士生导师
1996-05~1998-05,中国科学院心理研究所, 副研究员
1992-10~1996-05,中国科学院心理研究所, 助理研究员
社会兼职
2010-01-01-今,《心理科学进展》主编,
2010-01-01-今,《心理学报》编委,
2009-01-01-2017-12-31,中国心理学会生理心理学分会主任,
2009-01-01-今,中国心理学会生理心理学分会理事长,
2008-01-01-今,北京神经科学学会常务理事,

教授课程

临床心理学

科研活动

   
科研项目
( 1 ) 胚胎期阿片类药物对小鸡成瘾易感性影响的中枢GABA机制, 主持, 国家级, 2012-01--2015-12
( 2 ) DNA甲基化在阿片类药物调控情绪环路功能中的作用及其神经机制, 主持, 国家级, 2014-01--2016-12
( 3 ) 成瘾记忆相关神经元的识别和功能, 参与, 国家级, 2015-01--2019-08
代表性文章

(1) Peng Liu (#),Jianjun Zhang  (#),Ming Li,Nan Sui(*) ,Distinctive Roles of 5-aza-2′-deoxycytidine in Anterior Agranular Insular and Basolateral Amygdala in Reconsolidation of Aversive Memory Associated with Morphine in Rats.,Frontiers in Behavioral Neuroscience,2016,10.
(2) Ying Duan(#) ,Fang Shen  (#),Tingting Gu,Nan Sui(*),Addiction: from 
context-induced hedonia to appetite, based on transition of micro-behaviors in morphine abstinent tree shrews.,Frontiers in Psychology,2016,7:816.
(3) Jun Gao,Min Feng,Natashia Swalve,Collin Davis, Nan Sui
(*),Ming Li(*),Effects of repeated quetiapine treatment on conditioned avoidance responding in rats,European Journal of Pharmacology,2015,769:154-161.
(4) Min Feng ,Jun Gao,Nan Sui(*),Ming Li (*),Effects of central 
activation of serotonin 5-HT2A/2C or dopamine D-2/3 receptors on the acute and repeated effects of clozapine in the conditioned avoidance response test,Psychopharmacology,2015,232(7):1219-1230.
(5) 段颖
(#),沈芳(#), 隋南(*),强迫性用药行为的神经生物学机制研究进展,科学通报,2015,60(13):1160-1166.
(6) Jianjun Zhang(#) ,Jin Han,Nan Sui(*) ,Okadaic acid blocks the effects 
of 5-aza-2-deoxycytidine on consolidation, acquisition and retrieval of morphine-induced place preference in rats.,Neuropharmacology,2014,86:282-293.

(7) Weihai Chen (#)(*),Qi Zhang,Wenxin Su,Haorong Zhang,Yu Yang,Jing Qiao, Nan Sui(*),Ming Li(*),Effects of 5-hydroxytryptamine 2C receptor agonist MK212 and 2A receptor antagonist MDL100907 on maternal behavior in postpartum female rats.,Pharmacology Biochemistry and Behavior,2014,117:25-33.
(8) Wansen Yan,Yonghui Yan, Nan San
(*),The relationship between recent stressful life events, personality traits, perceived family functioning and internet addiction among college students.,Stress and Health,2014,30(1):3-11.
(9) Wansen Yan,Yonghui Li,Lin Xiao,Ning Zhu,Antoine Bechara, Nan Sui
(*),Working memory and affective decision-making in addiction: a neurocognitive comparison between heroin addicts, pathological gamblers and healthy controls.,Drug and Alcohol Dependence,2014,134:194-200.
(10) Yan Wu,Yonghui Li,Xiaoyan Yang, Nan Sui
(*),Differential effect of beta-adrenergic receptor antagonism in basolateral amygdala on reconsolidation of aversive and appetitive memories associated with morphine in rats.,Addiction Biology,2014,19(1):5-15.
(11) Fang Shen,Ying Duan,Shubo Jin, Nan Sui
(*),Varied behavioral responses induced by morphine in the tree shrew: a possible model for human opiate addiction.,Frontiers in Behavioral Neuroscience,2014,8:333-333.
(12) Xiao Jiang,Jianjun Zhang,Mengya Wang, Nan Sui
(*),Differential Muscarinic Modulation of Synaptic Transmission in Dorsal and Ventral Regions of the Rat Nucleus Accumbens Core,Physiological Research,2014,63(1):135-142.
(13) Keke Qi,Chuguang Wei,Yonghui Li
(*), Nan Sui(*),Orexin receptors within the nucleus accumbens shell mediate the stress but not drug
priming-induced reinstatement of morphine conditioned place preference,Frontiers in Behavioral Neuroscience,2013,7.
(14) Chunlu Li,Ning Zhu,Xiaolu Meng,Yonghui Li, Nan Sui
(*),Effects of inactivating the agranular or granular insular cortex on the acquisition of the morphine-induced conditioned place preference and naloxone-precipitated conditioned place aversion in rats,Journal of Psychopharmacology,2013,27(9):837-844.
(15) 张建军,刘鹏,朱宁, 隋南
(*),药物成瘾诱导相关大脑核团功能和行为改变的DNA甲基化机制,心理科学进展,2013,(06):975-981.
(16) Jun Gao,Yonghui Li,Ning Zhu,Stephen Brimijoin, Nan Sui
(*),Roles of dopaminergic innervation of nucleus accumbens shell and dorsolateralcaudate-putamen in cue-induced morphine seeking after prolonged abstinence and the underlying D1- and D2-like receptor mechanisms in rats,Journal of Psychopharmacology,2013,27(2):181-191.
(17) Min Feng, Nan Sui
(*),Ming Li(*),Avoidance disruptive effect of clozapine and olanzapine is potentiated by increasing the test trials: Further
test of the motivational salience hypothesis,Pharmacology Biochemistry and Behavior,2013,103(3):467-473.
(18) Chunlu Li,Ning Zhu,Yonghui Li,Xiaolu Meng,Jun Gao, Nan Sui
(*),The Role of Interoception and Insular Cortex in Addiction,Progress in Biochemistry and Biophysics,2013,40(1):15-21.
(19) Min Feng, Nan Sui
(*),Ming Li(*),Environmental and behavioral controls of the expression of clozapine tolerance: Evidence from a novel
across-model transfer paradigm.,Behavioural Brain Research,2013,238:178-187.
(20) Jiuqing Cheng,Yanhong Lu,Xiaodong Han,Claudia Gonzalez-Vallejo, Nan Sui
(*),Temporal Discounting in Heroin-Dependent Patients: No Sign Effect, Weaker Magnitude Effect, and the Relationship With Inhibitory Control,Experimental and Clinical Psychopharmacology,2012,20(5):400-409.
(21) Min Feng, Nan Sui
(*),Ming Li(*),Avoidance disruptive effect of clozapine and olanzapine is potentiated by increasing the test trials: Further
test of the motivational salience hypothesis,Pharmacology Biochemistry and Behavior,2012,103(3):467-473.
(22) Yan Wu,Yonghui Li,Xiaoyan Yang, Nan Sui
(*),Differential effect of beta-adrenergic receptor antagonism in basolateral amygdala on reconsolidation of aversive and appetitive memories associated with morphine in rats,Addic Biol,2012,20(5):400-409.
(23) Yan Wu,Yonghui Li,Jun Gao, Nan Sui
(*),Differential effect of NMDA receptor antagonist in the nucleus accumbens on reconsolidation of morphine-related positive and aversive memory in rats,European Journal of Pharmacology,2012,674(2-3):321-326.
(24) Xu, W.,Li, Y. H.,Tan, B. P.,Luo, X. J.,Xiao, L.,Zheng, X. G.,Yang, X. Y., Sui, N.
(*),Inhibition of the Acquisition of Conditioned Place Aversion by Dopaminergic Lesions of the Central Nucleus of the Amygdala in Morphine-Treated Rats,Physiological Research,2012,61(4):437-442.

(25) Xiaqin Sun,Xiaolu Meng,Jie Zhang,Yonghui Li,Liping Wang,Xiaoyan Qin(*), Nan Sui(*),Yan Zhang(*),GABA Attenuates Amyloid Toxicity by Downregulating its Endocytosis and Improves Cognitive Impairment,Journal of Alzheimer's Disease,2012,31(3):635-649。
(26) Jun Gao,Ning Zhu,Min Feng,Xiaolu Meng, Nan Sui
(*),Intranucleus accumbens SKF38393 improved the impaired acquisition of morphine-conditioned place preference in depression-like rats,PsyCh Journal,2012,1:2-14.
(27) Jiang, Juan,He, Xingu,Wang, Meng-Ya
(*), Sui, Nan(*)​,Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks,Behavioural Brain Research,2011,219(2):363-366.
(28) 严万森,李纾, 隋南
(*),成瘾人群的决策障碍:研究范式与神经机制,Advances in Psychological Science,2011,(05):652-663.
(29) Xingu He,Yunfei Bao,Yonghui Li, Nan Sui
(*),The effects of morphine at different embryonic ages on memory consolidation and rewarding properties of morphine in day-old chicks,Neuroscience Letters,2010,482(1):12-16.
(30) Jin Han,Yonghui Li,Dongmei Wang,Chuguang Wei,Xiaoyan Yang, Nan Sui
(*),Effect of 5-aza-2-deoxycytidine microinjecting into hippocampus and prelimbic cortex on acquisition and retrieval of cocaine-induced place preference in C57BL/6 mice,European Journal of
Pharmacology,2010,642(1-3):93-98.
(31) Lixia Zhao,Yushan Zhu,Dongmei Wang,Ming Chen,Ping Gao,Weiming Xiao,Guanhua Rao,Xiaohui Wang,Haijing Jin,Lin Xu, Nan Sui
(*),Quan Chen(*), Morphine induces Beclin 1-and ATG5-dependent autophagy in human neuroblastoma
SH-SY5Y cells and in the rat hippocampus,Autophagy,2010,6(3):386-394.
(32) Xingu He,Lin Xiao, Nan Sui
(*),Effects of SCH23390 and spiperone administered into medial striatum and intermediate medial mesopallium on rewarding effects of morphine in day-old chicks,European Journal of Pharmacology,2010,627(1-3):136-141.
(33) 蒋娟, 隋南
(*),汪萌芽(*),小鸡脑片突触反应长时程增强的细胞内记录和多参数分析,生理学报,2009,61(06):577-584.
(34) Bai, Y. J.,Li, Y. H.,Zheng, X. G.,Han, J.,Yang, X. Y., Sui, N.
(*),Orexin A attenuates unconditioned sexual motivation in male
rats,Pharmacology Biochemistry and Behavior,2009,91(4):581-589.

(35) Li, YH,Zheng, XG,Bai, YJ,Yang, XY, Sui, N(*),Opposite effects of MK-801 on the expression of food and morphine-induced conditioned place preference in rats,Journal of Psychopharmacology,2006,20(1):40-46.
(36) Ya Yang(#),Xigeng Zheng(#),Yongfu Wang,Jun Dong,Zhifang 
Dong,Jingxia Cai, Nan Sui(*),Lin Xu(*),Stress enables synaptic depression in CA1 synapses by acute and chronic morphine: Possible mechanisms for corticosterone on opiate addiction.,Journal of Neuroscience,2004,24(10):2412-2420


指导学生

已指导学生

李勇辉  01  19044  

白云静  01  19044  

刘彩谊  01  19044  

罗小景  01  19044  

郑希耕  01  19044  

王冬梅  01  19044  

鞠平  01  19044  

须卫  01  19044  

鲍云非  02  19044  

刘杰  02  19044  

李杰  01  19047  

何欣嘏  01  19047  

吴艳  01  19047  

程九清  02  19047  

黄砚北  02  51792  

魏楚光  02  51792  

蒋娟  01  51792  

韩锦  01  51792  

江潇  01  19047  

高军  01  19047  

李春禄  01  19047  

王园园  02  51792  

孟肖路  01  19047  

严万森  01  19047  

冯敏  01  19047  

祁可可  01  19047  

刘鹏  01  19047  

现指导学生

顾婷婷  02  19179  

王春光  01  68267  

金书博  02  72175  

蒋丰泽  01  71983  

尚文  02  72175  

段颖  01  71983  

陈星  02  72175