General

Rosa Lozano-Duran, Female, Principal Investigator,  CAS Center for Excellence in Molecular Plant Sciences(SIPPE)
Email: lozano-duran@sibs.ac.cn
Address: 317B Reaearch Center, Chenhua Road 3888, Songjiang District, Shanghai, China
Zip code: 201602


Research Areas

Molecular Plant - Virus Interactions

Education

2010/09  PhD, University of Málaga, Spain (Summa cum laude)

2007/06  M.Sc. Biotechnology, University Pablo de Olavide, Spain

2007/06   University Specialist in Scientific Journalism and Outreach, UNED (National University for Distance Education), Spain

2005/06  B.Sc. Biology, University of Málaga, Spain (first in graduating class)


Experience

Since May 2017 Principal Investigator, Shanghai Center for Plant Stress Biology, Shanghai, China

Since Nov 2017 Adjunct Professor, Institute of Plant Protection, Beijing, China

Since Oct 2017 Principal Investigator, CAS Center for Excellence in Molecular Plant Sciences

2015-2017      Junior Group Leader, Shanghai Center for Plant Stress Biology, Shanghai, China

2012-2015 Research Associate, The Sainsbury Laboratory, Norwich, United Kingdom

2011-2012   Postdoctoral Research Fellow, The Sainsbury Laboratory, Norwich, United Kingdom

2008 (3 months) Visiting student, Yale University, New Haven, CT, United States

2007 (3 months) Visiting student, Yale University, New Haven, CT, United States

2005-2010   PhD student, University of Málaga, Spain


Publications

30. Tabata Rosas-Diaz, Dan Zhang, Pengfei Fan, Liping Wang, Xue Ding, Yuli Jiang, Tamara Jimenez-Gongora, Laura Medina-Puche, Xinyan Zhao, Zhengyan Feng, Guiping Zhang, Xiaokun Liu, Eduardo R Bejarano, Li Tan, Heng Zhang, Jian-Kang Zhu, Weiman Xing, Christine Faulkner, Shingo Nagawa, Rosa Lozano-Duran. A virus-targeted plant receptor-like kinase promotes cell-to-cell spread of RNAi. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1388-1393. doi: 10.1073/pnas.1715556115.

 

29. Wei Y, Caceres-Moreno C, Jimenez-Gongora T, Wang K, Sang Y, Lozano-Duran R, Macho AP. The Ralstonia solanacerasum csp22 peptide, but not flagellin-derived peptides, is perceived by plants from the Solanaceae family. Plant Biotechnology Journal. In press.

 

28. Wang L, Tan H, Wu M, Jimenez-Gongora T, Tan L, Lozano-Duran R. Dynamic virus-dependent subnuclear localization of the capsid protein from a geminivirus. Front Plant Sci. In press.  

 

27. Wang L, Ding X, Xiao J, Jimenez-Gongora T, Liu R, Lozano-Duran R. Inference of a geminivirus-host protein-protein interaction network through affinity purification and mass spectrometry analysis. Viruses, Sep 25:9(10).

 

26. Rosas-Diaz T, Zhang D, Fan P, Wang L, Ding X, Jiang Y, Jimenez-Gongora T, Medina-Puche L, Zhao X, Feng Z, Zhang G, Liu X, Bejarano ER, Tan L, Zhu JK, Xing W, Faulkner C, Nagawa S, Lozano-Duran R. A plant receptor-like kinase promotes cell-to-cell spread of RNAi and is targeted by a virus (2017). BioRxiv, https://doi.org/10.1101/180380.

 

25. Luna AP, Rodriguez-Negrete EA, Morilla G, Wang L, Lozano-Duran R, Castillo AG, Bejarano ER. V2 from a curtovirus is a suppressor or post-transcriptional gene silencing. Journal of General Virology, in press.

 

24. Rosas-Díaz T, Zhang Dan, Lozano-Durán R. No evidence of seed transmissibility of Tomato yellow leaf curl virus in Nicotiana benthamiana. J Zhejiang Univ Sci B. 2017 May;18(5):437-440. doi: 10.1631/jzus.B1600463.

 

23. Rosas-Díaz T, Cana-Quijada P, Amorim-Silva V, Botella MA, Lozano-Durán R* and Bejarano ER*. Arabidopsis NahG plants as a suitable and efficient system for transient expression using Agrobacterium tumefaciens. Mol Plant. 2017 Feb 13;10(2):353-356. doi: 10.1016/j.molp.2016.11.005. Epub 2016 Nov 17. *Co-corresponding authors.

 

22. Lozano-Duran R* and Belkhadir Y*. A technical framework for studying the signaling nexus of brassinosteroids and immunity. Methods for Brassinosteroid Analysis. Methods Mol Biol. 2017;1564:49-61. doi: 10.1007/978-1-4939-6813-8_6. *Co-corresponding authors.

21. Rosas-Díaz T, Macho AP, Beuzón C, Lozano-Durán R*, Bejarano ER*. The C2 protein from the geminivirus Tomato yellow leaf curl Sardinia virus decreases sensitivity to jasmonates and suppresses jasmonate-mediated defences. Plants. 2016, 5, 8; doi:10.3390. *Co-corresponding authors.

 

20. Jiménez-Góngora T, Kim S-K, Lozano-Durán R* and Zipfel C*. Flg22-triggered immunity negatively regulates key BR biosynthetic genes. Front Plant Sci. 2015 Nov 9;6:981. *Co-corresponding authors.

 

19. Lozano-Durán R. Geminiviruses for biotechnology: the art of parasite taming. New Phytologist. New Phytol. 2015 Jul 27. doi: 10.1111/nph.13564.

 

18. Couto D, Stransfeld L, Arruabarrena A, Zipfel C* and Lozano-Durán R*. Broad application of a simple and affordable protocol for isolating plant RNA. BMC Res Notes. 2015 Apr 16;8:154.*Co-corresponding authors.

 

17. Macho AP, Lozano-Durán R and Zipfel C. Importance of tyrosine phosphorylation in receptor kinase complexes. Trends Plant Sci. 2015 May;20(5):269-72.

 

16. Lozano-Durán R* and Robatzek S (2015). 14-3-3 proteins in plant-pathogen interactions. Mol Plant Microbe Interact. 2015 May;28(5):511-8.  *Corresponding author.

 

15. Lozano-Durán R* and Zipfel C* (2015). Trade-off between growth and immunity: role of brassinosteroids. Trends in Plant Science. doi: 10.1016/j.tplants.2014.09.003. *Co-corresponding authors.

 

14. Alberto P Macho, Benjamin Schwessinger, Vardis Ntoukakis, Alexander Brutus, Cecile Segonzac, Sonali Roy, Yasuhiro Kadota, Man-ho Oh, Jan Sklenar, Paul Derbyshire, Rosa Lozano-Durán, Frederikke Gro Malinovsky, Jacqueline Monaghan, Frank L Menke, Steven C Huber, Sheng Yang and Cyril Zipfel (2014). A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation. Science, 343 (6178): 1509-1512. (Featured in The Faculty of 1000).

 

13. Rosa Lozano-Durán, Gildas Bourdais, Sheng Yang He and Silke Robatzek (2014). The bacterial effector HopM1 suppresses PAMP-triggered oxidative burst and stomatal immunity. New Phytologist, 202: 259–269. doi: 10.1111/nph.12651.

 

12.  Rosa Lozano-Durán, Freddy Boutrot, Alberto P Macho, Cecile Segonzac, Imre Somssich and Cyril Zipfel (2013). The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth. eLife, 2013;2:e00983.

 

11. Cañizares MC, Lozano-Durán R, Cantó T, Bejarano ER, Bisaro DM, Navas-Castillo J, Moriones E (2013). Effects of the crinivirus coat protein-interacting plant protein SAHH on post-transcriptional RNA silencing and its suppression. Molecular Plant-Microbe Interactions, 26(9):1004-15. (Editor’s pick).

 

10. Edgar Rodríguez-Negrete, Rosa Lozano-Durán, Alvaro Piedra-Aguilera, Lucia Cruzado, Eduardo R. Bejarano and Araceli G. Castillo (2013). Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Suppresses Transcriptional Gene Silencing. New Phytologist, 199(2):464-75.

 

9. Czosnek H, Eybishtz A, Sade D, Gorovits R, Bejarano ER, Rosas-Diaz T and Lozano-Duran R (2013). Tobacco Rattle virus-based Post Transcriptional Gene Silencing (TRV-PTGS) to discover host genes involved in the infection by the Tomato yellow leaf curl virus family and in the establishment of resistance to the virus. Viruses, 5(3): 998–1022.

 

8. Lozano-Durán R*, Caracuel Z* and Bejarano ER (2012). Plant Signaling and Behavior, 7(12): 1705–1708. C2 from Beet curly top virus meddles with the cell cycle: a novel function for an old pathogenicity factor. *Equal contributors.

 

7. Frei Dit Frey N, Mbengue M, Kwaaitaal M, Nitsch L, Altenbach D, Häweker H, Lozano-Duran R, Njo MF, Beeckman T, Huettel B, Borst JW, Panstruga R, Robatzek S (2012). Plasma membrane calcium ATPases are important components of receptor-mediated signaling in plant immune responses and development. Plant Physiology, 159(2):798-809.

 

6. Lozano-Durán R*, García I, Balzergue S, Romero LC, Bejarano ER (2012). Geminivirus C2 protein represses genes involved in sulfur assimilation, and this effect can be counteracted by jasmonate treatment. European Journal of Plant Pathology, 134(1):49-59. *Corresponding author.

 

5. Caracuel Z*, Lozano-Durán R*, Balzergue S, Arroyo MA, Rodríguez-Negrete EA, Bejarano ER (2012). C2 from Beet curly top virus promotes a cell environment suitable for efficient replication of geminiviruses, providing a novel mechanism of viral synergism. New Phytologist, 2012 May;194(3):846-58. *Equal contributors.

 

4. Lozano-Durán R*, Rosas-Díaz T*, Luna AP and Bejarano ER (2011). Identification of host genes involved in geminivirus infection using a reverse genetics approach. PLoS ONE 2011;6(7):e22383. *Equal contributors.

 

3. Lozano-Durán R, Bejarano ER (2011). Mutation in Arabidopsis CSN5A partially complements the defects in viral infectivity produced by L2 mutation in the geminivirus Beet curly top virus. Journal of Plant Pathology and Microbiology 2011, 2:3.

 

2. Lozano-Durán R* and Bejarano ER (2011). Geminivirus C2 protein might be the key player for geminiviral co-option of SCF-mediated ubiquitination. Plant Signaling and Behavior, 6:7, 1-3. *Corresponding author.

 

1. Lozano-Durán R, Rosas-Díaz T, Gusmaroli G, Luna AP, Tacconat L, Deng XW and Bejarano ER (2011). Geminiviruses subvert ubiquitination by altering CSN-mediated de-rubylation of SCF E3 ligase complexes and inhibit jasmonate signalling. The Plant Cell, Vol. 23: 1-19. (Featured in The Faculty of 1000).


Conferences

Conferences, invited

 

2018    Plant Biotic Stresses and Resistance Mechanisms, Vienna, Austria

2017    Plant-Virus Interactions Workshop, Hohhot, China

2017 Asian Conference for Plant Pathology, Jeju Island, Korea

2017 Symposium on Plant Development, Signaling, and Epigenetics, Shenzhen, China.

2017 Plant Biotic Interactions Workshop, Huhhot, China

2017 EMBO Workshop on Intercellular Communication in Development and Disease, Berlin, Germany

2017 EMBO Conference on Micro and Metabolic Regulators in Plants, Kerala,    India

2015 The 2nd International Brassinosteroid Conference, Wuhan, China

2015 12th International conference on the Frontiers of Plant Biology, Chengdu, China


Students

已指导学生

张丹  硕士研究生  071010-生物化学与分子生物学  

现指导学生

吴梦诗  博士研究生  071010-生物化学与分子生物学  

丁雪  博士研究生  071010-生物化学与分子生物学  

王立平  博士研究生  071010-生物化学与分子生物学  

丁怡  硕士研究生  071010-生物化学与分子生物学  

范芃菲  硕士研究生  071010-生物化学与分子生物学  

谭煌  博士研究生  071010-生物化学与分子生物学  

葛丹凤  博士研究生  071010-生物化学与分子生物学  

肖嘉靖  博士研究生  071010-生物化学与分子生物学  

于颜玲  硕士研究生  071007-遗传学  

高曼  博士研究生  071010-生物化学与分子生物学  

魏华  硕士研究生  071010-生物化学与分子生物学  

Honors & Distinctions

2015/03 100 Talent Program of the Chinese Academy of Sciences

2014/12 Finalist of The Tansley Medal Award, New Phytologist

2011/09  Postdoctoral fellowship from Fundación Ramón Areces

2010/03 Best Presentation Award, II Meeting of the Spanish Network for Plant Virology  

2007/09  EMBO Short term fellowship

2005/05 Predoctoral Fellowship from the Spanish Ministry of Education (FPU program)

2005/01 Predoctoral fellowship from Fundación Ramón Areces (declined)

2004/10 Introduction to Research Fellowship from the Spanish Council for Scientific Research (CSIC)

2003/10 Research Fellowship for Undergraduate Students from the Spanish Ministry of Education

1999/08  Stockholm Junior Water Prize

1999/09 XII Young Researchers Contest, Spanish Ministry of Education