基本信息
祁学斌  男  硕导  中国科学院昆明动物研究所
电子邮件: qixuebin@mail.kiz.ac.cn
通信地址: 云南省昆明市教场东路32号
邮政编码: 650223

招生信息

   
招生专业
071007-遗传学
招生方向
青藏高原人和动物的适应性进化

教育背景

2001-02--2004-06   International Livestock Research Institute (ILRI)   访问博士研究生
2000-09--2004-07   兰州大学   理学博士
1997-09--2000-07   甘肃农业大学   农学硕士
1993-09--1997-07   甘肃农业大学   农学学士

工作经历

   
工作简历
2014-01~现在, 中国科学院昆明动物研究所, 副研究员
2007-01~2013-12,中国科学院昆明动物研究所, 助理研究员
2004-10~2006-12,中国科学院昆明动物研究所, 博士后
2004-07~2004-09,International Livestock Research Institute (ILRI), 访问学者

专利与奖励

   
奖励信息
(1) 青藏高原史前人类定居历史及其对高原低氧环境的遗传适应机制, 二等奖, 省级, 2015
(2) 灵长类大脑进化与人类智力起源的遗传机制, 一等奖, 省级, 2014

出版信息

   
发表论文
(1) Bhandari, S.#, Zhang, X.#, Cui, C.#, Yangla, Liu, L., Ouzhuluobu, Baimakangzhuo, Gonggalanzi, Bai, C., Bianba, Peng, Y., Zhang, H., Xiang, K., Shi, H., Liu, S., Gengdeng, Wu, T., Qi, X.* & Su, B.* Sherpas share genetic variations with Tibetans for high-altitude adaptation, Mol Genet Genomic Med 5, 76-84, 2017, 通讯作者
(2) Guo, Y.#, He, Y.#, Cui, C.#, Ouzhuluobu, Baimakangzhuo, Duojizhuoma, Dejiquzong, Bianba, Peng, Y., Bai, C., Gonggalanzi, Pan, Y., Qula, Kangmin, Cirenyangji, Guo, W., Yangla, Zhang, H., Zhang, X., Zheng, W., Xu, S., Chen, H., Zhao, S., Cai, Y., Liu, S., Wu, T., Qi, X.* & Su, B.* GCH1 plays a role in high altitude adaptation of Tibetans, Zoological Research, 38, 155-162, 2017, 通讯作者
(3) Peng, Y.#, Cui, C.#, He, Y.#, Ouzhuluobu#, Zhang, H.#, Yang, D.#, Zhang, Q.#, Bianbazhuoma, Yang, L., He, Y., Xiang, K., Zhang, X., Bhandari, S., Shi, P., Yangla, Dejiquzong, Baimakangzhuo, Duojizhuoma, Pan, Y., Cirenyangji, Baimayangji, Gonggalanzi, Bai, C., Bianba, Basang, Ciwangsangbu, Xu, S., Chen, H., Liu, S., Wu, T.*, Qi, X.* & Su, B.* Down-regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-altitude Hypoxia, Mol Biol Evol 34, 818-830, 2017, 通讯作者
(4) Zhang, H.#, He, Y.#, Cui, C.#, Ouzhuluobu, Baimakangzhuo, Duojizhuoma, Dejiquzong, Bianba, Gonggalanzi, Pan, Y., Qula, Kangmin, Cirenyangji, Baimayangji, Bai, C., Guo, W., Yangla, Peng, Y., Zhang, X., Xiang, K., Yang, Z., Liu, S., Tao, X., Gengdeng, Zheng, W., Guo, Y., Wu, T., Qi, X.* & Su, B.* Cross-altitude analysis suggests a turning point at the elevation of 4,500m for polycythemia prevalence in Tibetans, Am J Hematol, 10.1002/ajh.24809, 2017, 通讯作者
(5) Zheng, W.#, He, Y.#, Cui, C.#, Ouzhuluobu, Dejiquzong, Peng, Y., Bai, C., Duojizhuoma., Gonggalanzi, Bianba, Baimakangzhuo, Pan, Y., Qula, Kangmin, Cirenyangji, Guo, W., Yangla, Zhang, H., Zhang, X., Guo, Y., Xu, S., Chen, H., Zhao, S., Cai, Y., Liu, S., Wu, T., Qi, X.* & Su, B.* EP300 contributes to high altitude adaptation of Tibetans by regulating nitric oxide production, Zoological Research, 38, 163-170, 2017, 通讯作者
(6) Yang, D., Peng, Y., Ouzhuluobu, Bianbazhuoma, Cui, C., Bianba, Wang, L., Xiang, K., He, Y., Zhang, H., Zhang, X., Liu, J., Shi, H., Pan, Y., Duojizhuoma, Dejiquzong, Cirenyangji, Baimakangzhuo, Gonggalanzi, Liu, S., Gengdeng, Wu, T., Chen, H., Qi, X.* & Su, B.* HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans., Human Mutation 37, 216-23, 2016, 通讯作者
(7) Yang, Z., Zhong, H., Chen, J., Zhang, X., Zhang, H., Luo, X., Xu, S., Chen, H., Lu, D., Han, Y., Li, J., Fu, L., Qi, X., Peng, Y., Xiang, K., Lin, Q., Guo, Y., Li, M., Cao, X., Zhang, Y., Liao, S., Peng, Y., Zhang, L., Guo, X., Dong, S., Liang, F., Wang, J., Willden, A., Seang Aun, H., Serey, B., Sovannary, T., Bunnath, L., Samnom, H., Mardon, G., Li, Q., Meng, A., Shi, H. & Su, B. A Genetic Mechanism for Convergent Skin Lightening during Recent Human Evolution, Molecular Biology and Evolution 33, 1177-87, 2016, 第 4 作者
(8) Bhandari, S., Zhang, X., Cui, C., Bianba, Liao, S., Peng, Y., Zhang, H., Xiang, K., Shi, H., Ouzhuluobu, Baimakongzhuo, Gonggalanzi, Liu, S., Gengdeng, Wu, T., Qi, X. & Su, B.* Genetic evidence of a recent Tibetan ancestry to Sherpas in the Himalayan region, Scientific Reports 5, 16249, 2015, 通讯作者
(9) Zhang, X., Liao, S., Qi, X., Liu, J., Kampuansai, J., Zhang, H., Yang, Z., Serey, B., Sovannary, T., Bunnath, L., Seang Aun, H., Samnom, H., Kangwanpong, D., Shi, H. & Su, B.* Y-chromosome diversity suggests southern origin and Paleolithic backwave migration of Austro-Asiatic speakers from eastern Asia to the Indian subcontinent, Scientific Reports 5, 15486, 2015, 第 1 作者
(10) Zhang, X., Kampuansai, J., Qi, X., Yan, S., Yang, Z., Serey, B., Sovannary, T., Bunnath, L., Aun, H.S., Samnom, H., Kutanan, W., Luo, X., Liao, S., Kangwanpong, D., Jin, L., Shi, H. & Su, B.* An updated phylogeny of the human Y-chromosome lineage O2a-M95 with novel SNPs, PLoS One 9, e101020, 2014, 第 1 作者
(11) Qi, X., Cui, C., Ouzhuluobu, Wu, T. & Su, B.* Prehistoric Colonization and Demographic History of Modern Humans on the Tibetan Plateau, eLS, John Wiley and Sons Ltd, Chichester, 2014, 第 1 作者
(12) A genetic adaptive pattern-low hemoglobin concentration in the Himalayan highlanders, Chinese Journal of Applied Physiology 29, 481-493, 2014, 通讯作者
(13) Hematological parameters in high altitude residents: Tibetan natives versus Han migrants, Chinese Journal of Applied Physiology, 2014, 通讯作者
(14) Qi, X., Cui, C., Peng, Y., Zhang, X., Yang, Z., Zhong, H., Zhang, H., Xiang, K., Cao, X., Wang, Y., Ouzhuluobu, Basang, Ciwangsangbu, Bianba, Gonggalanzi, Wu, T., Chen, H., Shi, H. & Su, B.* Genetic evidence of paleolithic colonization and neolithic expansion of modern humans on the tibetan plateau, Molecular Biology and Evolution 30(8): 1761-1778, 2013, 第 1 作者
(15) Xiang, K., Ouzhuluobu, Peng, Y., Yang, Z., Zhang, X., Cui, C., Zhang, H., Li, M., Zhang, Y., Bianba, Gonggalanzi, Basang, Ciwangsangbu, Wu, T., Chen, H., Shi, H., Qi, X. & Su, B.* Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation, Molecular Biology and Evolution 30 (8): 1889-1898, 2013, 通讯作者
(16) Analysis of mitochondrial genome diversity identifies novel and ancient maternal lineages in Cambodian aborigines, Nature Communications 4:2599, 2013, 第 1 作者
(17) Genetic evidence of an East Asian origin and Paleolithic northward migration of Y-chromosome haplogroup N, PLoS ONE 8(6): e66102, 2013, 第 1 作者
(18) Extended Y chromosome investigation suggests postglacial migrations of modern humans into East Asia via the northern route, Molecular Biology and Evolution, 28: 717-727, 2011, 第 3 作者
(19) Assessment of cattle genetic introgression into domestic yak populations using mitochondrial and microsatellite DNA markers, Animal Genetics 41: 242-252, 2010, 第 1 作者
(20) Global distribution of Y-chromosome haplogroup C reveals the prehistoric migration routes of African exodus and early settlement in East Asia, Journal of Human Genetics, 55: 428-435, 2010, 第 3 作者
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发表著作
( 1 ) 进化, Evolution, 科学出版社, 2010-04, 第 3 作者
( 2 ) 高原病的诊断、预防和治疗指南, Guidelines for the Diagnosis, Prevention and Treatment of High Altitutde Disease, 兰州大学出版社, 2014-02, 第 5 作者

科研活动

   
科研项目
( 1 ) 青藏高原史前人类定居与迁徙模式的遗传学研究, 主持, 国家级, 2014-01--2017-12
( 2 ) 牦牛的人工选择、自然选择机制与研究, 主持, 国家级, 2013-01--2017-08
( 3 ) 慢性高原低氧损伤与长期适应的分子机制, 主持, 国家级, 2012-01--2016-08
( 4 ) 家养牦牛的起源、驯化与群体扩散的遗传学研究, 主持, 国家级, 2009-01--2011-12
( 5 ) 家养牦牛的起源、驯化及其群体扩散的研究, 主持, 部委级, 2008-01--2010-12
( 6 ) 中国人群中乳糖酶基因的变异及其分子进化, 主持, 国家级, 2008-01--2008-12
( 7 ) 中国汉藏民族人群中乳糖酶基因的变异及其分子进化, 主持, 省级, 2007-01--2010-12
( 8 ) 动物脑容量进化的遗传机制及其关键基因的功能解析, 参与, 国家级, 2014-06--2019-08
( 9 ) 解析藏族人群高原肺动脉高压的调控机制及其对高原低氧环境适应的遗传效应, 主持, 国家级, 2017-01--2018-12
( 10 ) 藏族人群高原低氧适应关键基因EPAS1和EGLN1互作的分子机制及功能验证研究, 参与, 国家级, 2017-01--2019-12
参与会议
(1)Genetic evidence of Paleolithic colonization and Neolithic expansion of modern humans on the Tibetan Plateau   祁学斌   2014-05-25