基本信息
刘金涛 男 博导 上海有机化学研究所
电子邮件:jtliu@sioc.ac.cn
通信地址:上海零陵路345号
邮政编码:200032

研究领域

有机氟化学/功能材料

招生信息

   
招生专业
070303-有机化学
招生方向
有机氟化学
功能材料

教育背景

1987-09--1992-12 中国科学院上海有机化学研究所 理学博士
1983-09--1987-07 复旦大学 理学学士
学历
研究生
学位
博士

工作经历

   
工作简历
2000-12~现在, 中国科学院上海有机化学研究所, 研究员、博导、课题组长
1996-10~2000-11,中国科学院上海有机化学研究所, 副研究员、课题组长
1994-03~1996-07,美国Clemson大学, 博士后
1993-03~1993-12,中国科学院上海有机化学研究所, 助理研究员

教授课程

有机氟化学

专利与奖励

   

出版信息

   
发表论文
[1] Li, JiaHui, Xu, JiaHong, Jiang, Min, Song, LiPing, Liu, JinTao. The Perfluoroalkylthiolation Reaction of Indoles and Activated Arenes with Perfluoroalkanesulfenic Acids. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2022, 2022(43): [2] DongWei Sun, YongYan Zhou, Min Jiang, Tang Nian, JinTao Liu. CF3SOCl-promoted intramolecular cyclization of β-diketones: An efficient synthesis of flavones. TETRAHEDRON[J]. 2021, 91: http://dx.doi.org/10.1016/j.tet.2021.132226.
[3] Xu, JiaHong, Jiang, Min, Song, LiPing, Liu, JinTao. A New Approach for the Synthesis of Perfluoroalkanesulfenic Acids. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2021, 2021(12): 1919-1923, https://www.webofscience.com/wos/woscc/full-record/WOS:000632946900014.
[4] Qian Liu, XiaoBo Li, Min Jiang, ZhenJiang Liu, JinTao Liu. Synthesis of α-alkynyl perfluoroalkyl sulfoxides by the reaction of terminal alkynes and perfluoroalkanesulfinyl chlorides. TETRAHEDRON[J]. 2021, 83: http://dx.doi.org/10.1016/j.tet.2021.131994.
[5] Zhao, Juan, Jiang, Min, Liu, JinTao. Transition metal-free aminofluorination of beta,gamma-unsaturated hydrazones: base-controlled regioselective synthesis of fluorinated dihydropyrazole and tetrahydropyridazine derivatives (vol 5, pg 1155, 2018). ORGANIC CHEMISTRY FRONTIERSnull. 2020, 7(10): 1297-1297, https://www.webofscience.com/wos/woscc/full-record/WOS:000536816700013.
[6] Yan, Jun, Jiang, Min, Song, LiPing, Liu, JinTao. Oxytrifluoromethylthiolation of 2,3-Allenoates with Trifluoromethanesulfinyl Chloride: A Synthetic Approach to Trifluoromethylthiolated 4-Oxo-2(E)-alkenoates and Furans. ADVANCED SYNTHESIS & CATALYSIS[J]. 2020, 362(14): 2882-2887, https://www.webofscience.com/wos/woscc/full-record/WOS:000541484500001.
[7] Li, Peng, Sun, DongWei, Jiang, Min, Liu, JinTao. Asymmetric aza-Henry reaction of fluoromethylated imines catalyzed by cinchona-derived bifunctional thiourea. TETRAHEDRON[J]. 2019, 75(5): 603-607, http://dx.doi.org/10.1016/j.tet.2018.12.055.
[8] Li, Xiaobo, Zhao, Juan, Liu, Qian, Jiang, Min, Liu, Jintao. Addition of Perfluoroalkanesulfenic Acids to Alkynes and Allenes. CHINESE JOURNAL OF ORGANIC CHEMISTRY[J]. 2019, 39(1): 183-191, http://dx.doi.org/10.6023/cjoc201808036.
[9] Yue, ShengLi, Jiang, Min, Li, Hui, Liu, JinTao. Triflylation of 1,4-Benzoquinones with sodium trifluoromethanesulfinate. JOURNAL OF FLUORINE CHEMISTRY[J]. 2019, 228: http://dx.doi.org/10.1016/j.jfluchem.2019.109410.
[10] Sun, DongWei, Jiang, Min, Liu, JinTao. Novel Bifunctionalization of Activated Methylene: Base-Promoted Trifluoromethylthiolation of beta-Diketones with Trifluoromethanesulfinyl Chloride. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2019, 25(46): 10797-10802, https://www.webofscience.com/wos/woscc/full-record/WOS:000481420300004.
[11] Jin-Tao Liu. CuX2-mediated halocyclization of 1,1-difluoro-2,3-allenylphosphonic acid monoesters esynthesis of novel cyclic phosphate mimics. Tetrahedron. 2018, [12] Sun, DongWei, Jiang, Xu, Jiang, Min, Lin, Yun, Liu, JinTao. POCl3-Promoted Trifluoromethylthiolation-Based Vicinal Bifunctionalization of Indoles with CF3SO2Na. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 2018(18): 2078-2081, https://www.webofscience.com/wos/woscc/full-record/WOS:000432225700005.
[13] Zhao, Juan, Jiang, Min, Liu, JinTao. Transition metal-free aminofluorination of ss,gamma-unsaturated hydrazones: base-controlled regioselective synthesis of fluorinated dihydropyrazole and tetrahydropyridazine derivatives. ORGANIC CHEMISTRY FRONTIERS[J]. 2018, 5(7): 1155-1159, https://www.webofscience.com/wos/woscc/full-record/WOS:000428670900014.
[14] Zhao, Juan, Jiang, Min, Liu, JinTao. Synthesis of Fluoromethyl-Substituted Isoxazolines via Transition Metal-Free Oxyfluorination of Alkenyl Oximes. ADVANCED SYNTHESIS & CATALYSIS[J]. 2017, 359(10): 1626-1630, https://www.webofscience.com/wos/woscc/full-record/WOS:000401528100004.
[15] JunLi Li, XianJin Yang, Min Jiang, JinTao Liu. The preparation and cycloaddition reaction of 1-sulfonyl-1-trifluoromethyl allenes. TETRAHEDRON LETTERS[J]. 2017, 3377-3379, http://dx.doi.org/10.1016/j.tetlet.2017.07.050.
[16] Xu, ZeFeng, Jiang, Min, Liu, JinTao. Preparation and Reactions of Perfluoroalkanesulfenyl Chlorides. CHINESE JOURNAL OF CHEMISTRY[J]. 2017, 35(4): 442-446, http://lib.cqvip.com/Qikan/Article/Detail?id=672412960.
[17] Cao, ChunRu, Ou, Song, Jiang, Min, Liu, JinTao. An efficient method for the synthesis of gem-difluoroolefins. TETRAHEDRON LETTERS[J]. 2017, 58(5): 482-485, http://dx.doi.org/10.1016/j.tetlet.2016.12.070.
[18] Sun, DongWei, Jiang, Xu, Jiang, Min, Lin, Yun, Liu, JinTao. Selective Trifluoromethylthiolation and Trifluoromethylsulfinylation of Indoles with Sodium Trifluoromethanesulfinate Promoted by Phosphorus Reagents. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2017, 2017(24): 3505-3511, https://www.webofscience.com/wos/woscc/full-record/WOS:000405126400017.
[19] Zhang Fan, Jiang Min, Liu JinTao. Base-controlled reaction of α,β-unsaturated trifluoromethyl ketone and dialkyl phosphite. TETRAHEDRON LETTERS[J]. 2017, 58(19): 1871-1874, http://dx.doi.org/10.1016/j.tetlet.2017.04.002.
[20] Li, XiaoBo, Zhao, Juan, Jiang, Min, Liu, JinTao. The addition of polyfluoroalkanesulfenic acids to alkenes. JOURNAL OF FLUORINE CHEMISTRY[J]. 2016, 185: 24-30, http://dx.doi.org/10.1016/j.jfluchem.2016.03.002.
[21] Wang, Yanan, Jiang, Min, Liu, JinTao. Copper-Catalyzed Diastereoselective Synthesis of Trifluoromethylated Tetrahydrofurans. ADVANCED SYNTHESIS & CATALYSIS[J]. 2016, 358(8): 1322-1327, https://www.webofscience.com/wos/woscc/full-record/WOS:000374556600015.
[22] Li, JunLi, Yang, XianJin, Wang, Yanan, Liu, JinTao. Synthesis of trifluoromethylated compounds from alcohols via alkoxydiphenylphosphines. JOURNAL OF FLUORINE CHEMISTRY[J]. 2015, 178: 254-259, http://dx.doi.org/10.1016/j.jfluchem.2015.08.011.
[23] Wang, Yanan, Jiang, Min, Liu, JinTao. Copper-catalyzed stereoselective oxytrifluoro-methylation of propargyl amides for the construction of oxazolines. ORGANIC CHEMISTRY FRONTIERS[J]. 2015, 2(5): 542-547, https://www.webofscience.com/wos/woscc/full-record/WOS:000364445300016.
[24] Yang, Kai, Jiang, Min, Liu, JinTao. Synthesis of Chiral beta-Aminomalonates from 2-Chlorotetrafluoroethanesulfinyl Aldimines through the Mannich Reaction. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 2015(14): 3109-3115, https://www.webofscience.com/wos/woscc/full-record/WOS:000354212000018.
[25] Cao, ChunRu, Jiang, Min, Liu, JinTao. Metal-Mediated Reformatsky Reaction of Bromodifluoromethyl Ketone and Imine. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY[J]. 2015, 2015(5): 1144-1151, https://www.webofscience.com/wos/woscc/full-record/WOS:000349391700028.
[26] Yang, Kai, Liu, JinTao. One-pot asymmetric reductive amination of ketones induced by polyfluoroalkanesulfinamide. JOURNAL OF FLUORINE CHEMISTRY[J]. 2015, 173: 18-22, http://dx.doi.org/10.1016/j.jfluchem.2015.01.019.
[27] Jin-Tao Liu. Asymmetric Pudovik reaction of chiral fluoroalkyl α,β-unsaturated ketimines and diphenyl phosphate. Chin. J. Chem.. 2014, [28] Yan Zhao, XiaoJin Wang, Yun Lin, ChenXin Cai, JinTao Liu. Highly enantioselective direct Michael addition of 1,3-dicarbonyl compounds to β-fluoroalkyl-α-nitroalkenes. TETRAHEDRON. 2014, 2523-2528, http://dx.doi.org/10.1016/j.tet.2014.02.062.
[29] Yang Kai, Liu Lijuan, Liu Jintao. The Synthesis and Strecker Reaction of 2-Chlorotetrafluoroethanesulfinyl Ketimines. J. ORG. CHEM.[J]. 2014, 79(7): 3215-3220, http://ir.sioc.ac.cn/handle/331003/38837.
[30] Yan Zhao, XiaoJin Wang, ChenXin Cai, JinTao Liu. Organocatalytic aldol and domino Michael-aldol reactions of α,α-difluoro-β-keto esters with acetone. JOURNAL OF FLUORINE CHEMISTRY. 2014, 61-66, http://dx.doi.org/10.1016/j.jfluchem.2014.06.010.
[31] Liu, LiJuan, Liu, JinTao. 2-Chlorotetrafluoroethanesulfinamide induced asymmetric vinylogous Mannich reaction. TETRAHEDRON[J]. 2014, 70(6): 1236-1245, http://dx.doi.org/10.1016/j.tet.2013.12.071.
[32] 王亚南, 蒋敏, 刘金涛. Copper-Catalyzed Regioselective Oxytrifluoromethylation of Allenes Using a CF3-Transfer Reagent. ADVSYNTHCATAL[J]. 2014, 356(14-15): 2907-2912, http://ir.sioc.ac.cn/handle/331003/38840.
[33] Jin-Tao Liu. Synthesis and identification of novel solution-stable sulfenic acids: perfluoroalkanesulfenic acids. Eur. J. Org. Chem.. 2014, [34] Cao Chunru, Ou Song, Jiang Min, Liu Jintao. A practical route for the highly stereoselective synthesis of tetrasubstituted fluoroalkenes. ORG. BIOMOL. CHEM.[J]. 2014, 12(3): 467-473, http://ir.sioc.ac.cn/handle/331003/38832.
[35] 刘丽娟, 刘金涛. Zinc promoted asymmetric propargylation of N-(2-chlorotetrafluoroethanesulfin)imines. J. FLUOR. CHEM.[J]. 2014, 168: 44-49, http://ir.sioc.ac.cn/handle/331003/38843.
[36] Xu Zefeng, Cai Chenxin, Jiang Min, Liu Jintao. Copper-Catalyzed Regio- and Stereoselective O-Arylation of Enolates. ORG. LETT.[J]. 2014, 16(13): 3436-3439, http://ir.sioc.ac.cn/handle/331003/38838.
[37] Wang, Yanan, Jiang, Min, Liu, JinTao. Copper-Catalyzed Intramolecular Carbotrifluoromethylation of Alkynes for the Construction of Trifluoromethylated Heterocycles. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2014, 20(47): 15315-15319, https://www.webofscience.com/wos/woscc/full-record/WOS:000345234800006.
[38] Wang, Yanan, Jiang, Min, Liu, JinTao. Enantioselective Michael addition of cyclic ketones to nitroolefins catalyzed by a novel fluorine-insertion organocatalyst. TETRAHEDRON-ASYMMETRY[J]. 2014, 25(3): 212-218, http://dx.doi.org/10.1016/j.tetasy.2013.12.015.
[39] 欧松, 曹春如, 蒋敏, 刘金涛. A Synthetic Approach to Tetrasubstituted Alkenes: Using beta-Carbonyl Benzothiazol-2-yl Sulfones as Electrophiles. EUR. J. ORG. CHEM.[J]. 2013, 2013(29): 6510-6513, http://www.irgrid.ac.cn/handle/1471x/869986.
[40] Ou, Song, Jiang, Min, Liu, JinTao. Synthesis of 2,2-difluoro-2H-chromenes through the tandem reaction of ethyl 3-bromo-3,3-difluoropropionate with salicylaldehyde derivatives. TETRAHEDRON[J]. 2013, 69(51): 10820-10825, http://dx.doi.org/10.1016/j.tet.2013.10.091.
[41] Xu Zefeng, Cai Chenxin, Liu Jintao. Copper-Catalyzed Regioselective Reaction of Internal Alkynes and Diaryliodonium Salts. ORG. LETT.[J]. 2013, 15(9): 2096-2099, http://www.irgrid.ac.cn/handle/1471x/848171.
[42] Hui Yao, ChunRu Cao, Min Jiang, JinTao Liu. Metal-mediated Reformatsky reaction of bromodifluoromethyl ketone and aldehyde using water as solvent. JOURNAL OF FLUORINE CHEMISTRY[J]. 2013, 45-50, http://dx.doi.org/10.1016/j.jfluchem.2013.08.012.
[43] Zhang Tao, Zhuo Ying, Jia XiaoPeng, Liu JinTao, Gao Hong, Song FuHang, Liu Mei, Zhang LiXin. Cloning and characterization of the gene cluster required for beauvericin biosynthesis in Fusarium proliferatum. SCIENCE CHINA-LIFE SCIENCES[J]. 2013, 56(7): 628-637, http://dx.doi.org/10.1007/s11427-013-4505-1.
[44] Zhen-Jiang Liu, Fan Zhang, Jin-Tao Liu. Regiospecific and diastereoselective aldol reaction of chiral N-sulfinyl metalloenamines with α,β-unsaturated trifluoromethyl ketones: Asymmetric synthesis of tertiary trifluoromethyl allylic carbinols. JOURNAL OF FLUORINE CHEMISTRY. 2012, 133: 102-107, http://dx.doi.org/10.1016/j.jfluchem.2011.09.002.
[45] Zhang, Tao, Jia, XiaoPeng, Zhuo, Ying, Liu, Mei, Gao, Hong, Liu, JinTao, Zhang, Lixin. Cloning and characterization of a novel 2-ketoisovalerate reductase from the beauvericin producer Fusarium proliferatum LF061. BMC BIOTECHNOLOGY[J]. 2012, 12(1): 55-55, http://dx.doi.org/10.1186/1472-6750-12-55.
[46] Jiang, XiuZhao, Cai, ChenXin, Liu, Tao, Uno, Hidemitsu. Novel syntheses and properties of meso-tetraaryl-octabromo-tetranaphtho2,3porphyrins (Ar(4)Br(8)TNPs). ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2012, 10(15): 3110-3115, https://www.webofscience.com/wos/woscc/full-record/WOS:000301958100028.
[47] Jin-Tao Liu. 8-Diazabicyclo[5.4.0]undec-7-ene (DBU) catalyzed regiospecific and diastereoselective reaction of chiral N-(tert-butanesulfinyl) ketimines and α,β-unsaturated trifluoromethyl ketones. Chin. J. Chem.. 2011, [48] Jin-Tao Liu. 2-Chlorotetrafluoroethanesulfinamide induced diastereoselective three-component aminoallylation of aromatic aldehydes. 2011, [49] 林云, 刘金涛. A facile method to construct cyclic alpha,alpha-difluoromethylenephosphonate-A novel cyclic phosphate mimic. J. FLUOR. CHEM.[J]. 2011, 132(5): 310-317, http://www.irgrid.ac.cn/handle/1471x/594171.
[50] 刘丽娟, 陈玲君, 李鹏, 李晓波, 刘金涛. Optically Pure Polyfluoroalkanesulfinamides: Synthesis and Application as Promising and Monitorable Chiral Auxiliaries. J. ORG. CHEM.[J]. 2011, 76(11): 4675-4681, http://www.irgrid.ac.cn/handle/1471x/594170.
[51] Li Peng, Liu Lijuan, Liu Jintao. Per(poly) fluoroalkanesulfinamides assisted diastereoselective three-component inverse-electron-demand aza Diels-Alder reaction. ORG. BIOMOL. CHEM.[J]. 2011, 9(1): 74-77, http://www.irgrid.ac.cn/handle/1471x/594169.
[52] 张帆, 刘振江, 刘金涛. Asymmetric aza-Henry reaction of chiral fluoroalkyl alpha,beta-unsaturated N-tert-butanesulfinyl ketoimines: an efficient approach to enantiopure fluoroalkylated alpha,beta-diamines and alpha,beta-diamino acids. ORG. BIOMOL. CHEM.[J]. 2011, 9(10): 3625-3628, http://www.irgrid.ac.cn/handle/1471x/594172.
[53] Jian Xu, Zhen-Jiang Liu, Xian-Jin Yang, Li-Min Wang, Guan-Long Chen, Jin-Tao Liu. One-pot asymmetric synthesis of α-trifluoromethylated amines from α-trifluoromethyl ketones. TETRAHEDRON. 2010, 66(46): 8933-8937, http://dx.doi.org/10.1016/j.tet.2010.09.047.
[54] Gao, Hong, Liu, Mei, Zhou, Xianlong, Liu, Jintao, Zhuo, Ying, Gou, Zhongxuan, Xu, Bing, Zhang, Wenquan, Liu, Xiangyang, Luo, Aiqun, Zheng, Chuansen, Chen, Xiaoping, Zhang, Lixin. Identification of avermectin-high-producing strains by high-throughput screening methods. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2010, 85(4): 1219-1225, http://www.irgrid.ac.cn/handle/1471x/768308.
[55] Li, Peng, Liu, ZhenJiang, Liu, JinTao. Iodocyclization of trifluoromethylallenic phosphonates: an efficient approach to trifluoromethylated oxaphospholenes. TETRAHEDRON[J]. 2010, 66(51): 9729-9732, http://dx.doi.org/10.1016/j.tet.2010.10.040.
[56] Gao, Hong, Liu, Mei, Zhuo, Ying, Zhou, Xianlong, Liu, Jintao, Chen, Difei, Zhang, Wenquan, Gou, Zhongxuan, Shang, Peng, Zhang, Lixin. Assessing the Potential of an Induced-Mutation Strategy for Avermectin Overproducers. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2010, 76(13): 4583-4586, http://124.16.144.217/handle/311023/1501.
[57] Fan Zhang, Zhen-Jiang Liu, Jin-Tao Liu. Michael addition of N-sulfinyl metalloenamines to β-trifluoromethyl-α,β-unsaturated ester: an efficient access to chiral 4-trifluoromethyl-2-piperidones. TETRAHEDRON. 2010, 66(34): 6864-6868, http://dx.doi.org/10.1016/j.tet.2010.06.047.

科研活动

   
科研项目
(1) 氟烷基次磺酸及其衍生物的合成及性质研究,主持,国家级,2016-01--2019-12
(2) 手性含氟化合物的合成及其在不对称反应中的应用研究研究,主持,国家级,2012-01--2015-12

指导学生

已指导学生

王小进  01  19132  

赵富录  01  19132  

林云  01  19132  

欧松  01  19132  

杨先金  01  19132  

李俊力  01  19132  

李晓波  01  19132  

陈玲君  02  19132  

梅英桥  01  19132  

刘振江  01  19132  

姚辉  02  19132  

赵燕  01  19132  

张帆  01  19132  

李鹏  01  19132  

耿晓宇  02  19132  

刘丽娟  01  19132  

姜秀召  01  19132  

曹春如  01  19132  

徐泽锋  01  19132  

杨凯  01  19132  

王亚南  01  19132  

现指导学生

赵娟  01  19132  

孙东伟  01  19132