基本信息

雷和花  女  硕导  中国科学院精密测量科学与技术创新研究院
电子邮件: leihh@wipm.ac.cn
通信地址: 武汉市武昌小洪山西30号物数所波谱楼
邮政编码: 430071

研究领域

环境毒理和环境健康代谢组学研究

招生信息

   
招生专业
070302-分析化学
招生方向
代谢组学

教育背景

2005-09--2008-06   中国科学院水生生物研究所   博士研究生博士学位
2002-09--2005-06   中南民族大学   研究生硕士学位
1997-09--2001-06   中南民族大学   本科学士学位

工作经历

   
工作简历
2014-10~现在, 中国科学院武汉物理与数学研究所, 副研究员
2011-05~2014-09,中国科学院武汉物理与数学研究所, 助理研究员
2008-07~2011-04,中国科学院武汉物理与数学研究所, 博士后

出版信息

   
发表论文
(1) Targeted metabolomics reveals that 2,3,7,8-tetrachlorodibenzofuran exposure induces hepatic steatosis in male mice, Environmental Pollution, 2020, 第 3 作者
(2) In vitro effects of Triclocarban on adipogenesis in murine preadipocyte and human hepatocyte, Journal of Hazardous Materials, 2020, 通讯作者
(3) Dose-Dependent Effects of Triclocarban Exposure on Lipid Homeostasis in Rats, Chem. Res. Toxicol., 2019, 通讯作者
(4) Quantitative analysis of 10 classes of phospholipids by ultrahighperformance liquid chromatography tandem triple-quadrupole mass spectrometer, Analyst, 2019, 第 2 作者
(5) Stimulated phospholipid synthesis is key for hepatitis B virus replications, Scientific Reports, 2019, 第 2 作者
(6) ombined Metabonomic and Quantitative RT-PCR Analyses Revealed Metabolic Reprogramming Associated with Fusarium graminearum Resistance in Transgenic Arabidopsis thaliana, FRONTIERS IN PLANT SCIENCE, 2018, 第 4 作者
(7) Interspecies Developmental Differences in Metabonomic Phenotypes of Lycium ruthenicum and L-barbarum Fruits, JOURNAL OF PROTEOME RESEARCH, 2018, 第 4 作者
(8) Dynamic metabolic responses of brown planthoppers towards susceptible and resistant rice plants, PLANT BIOTECHNOLOGY JOURNAL, 2017, 第 4 作者
(9) Simultaneous Quantification of Amino Metabolites in Multiple Metabolic Pathways Using Ultra-High Performance Liquid Chromatography with Tandemmass Spectrometry, SCIENTIFIC REPORTS, 2017, 第 3 作者
(10) Gender differences of peripheral plasma and liver metabolic profiling in APP/PS1 transgenic AD mice, Neuroscience, 2016, 第 3 作者
(11) Reprogramming of Seed Metabolism Facilitates Pre-harvest Sprouting Resistance of Wheat, Scientific Reports, 2016, 第 5 作者
(12) The metabolic responses to hepatitis B virus infection shed new light on pathogenesis and targets for treatment, Scientific Reports, 2015, 第 4 作者
(13) Metabonomic Analysis Reveals Efficient Ameliorating Effects of Acupoint Stimulations on the Menopause-caused Alterations in Mammalian Metabolism, Scientific Reports, 2014, 第 4 作者
(14) Systemic Responses of BALB/c Mice to Salmonella typhimurium Infection, Journal of Proteome Research, 2014, 第 2 作者
(15) Dynamic changes in metabolic profiles of rats subchronically exposed to mequindox., Molecular BioSystems, 2014, 第 4 作者
(16) 微囊藻毒素在银鲫肠道中的累积及其病理学影响, 生态毒理学报, 2014, 第 2 作者
(17) Metabolic Influence of Acute Cyadox Exposure on Kunming Mice, Journal of Proteome Research, 2013, 第 3 作者
(18) High-Fat Diet Induces Dynamic Metabolic Alterations in Multiple Biological Matrices of Rats, Journal of Proteome Research, 2013, 第 4 作者
(19) Combined NMR and GC?MS Analyses Revealed Dynamic Metabolic Changes Associated with the Carrageenan-Induced Rat Pleurisy,  Journal of Proteome Research, 2013, 第 4 作者
(20) Renal accumulation and effects of intraperitoneal injection of extracted microcystins in omnivorous crucian carp (Carassius auratus), Toxicon, 2013, 第 3 作者
(21) Systems Responses of Rats to Mequindox Revealed by Metabolic and Transcriptomic Profiling, Journal of Proteome Research, 2012, 第 5 作者
(22)  Dynamic metabolic response of mice to acute mequindox exposure., Journal of Proteome Research , 2011, 第 3 作者

科研活动

   
科研项目
( 1 ) 微囊藻毒素低剂量暴露影响大鼠代谢组变化的核磁共振研究, 主持, 国家级, 2013-01--2015-12