微流控芯片

   

070302-分析化学
100704-药物分析学

生物微流控芯片
生物微纳材料

2001-09--2007-01   中国科学院大连化学物理研究所   博士

   

2007-04~现在, 中国科学院大连化学物理研究所, 副研究员

   

（1） 全集成细胞芯片系统, 二等奖, 省级, 2017
（2） 全集成微流控芯片核酸分析系统, 一等奖, 市地级, 2010

   

[1] Xuening Jiang, Xueping Zhao, Yuxin Sun, Yige He, Lei Jiang. Laser-patterned PEDOT:PSS-aramid nanofiber composite electrodes for in-plane supercapacitors with high performance, shape-diversity and ultrahigh deformation resistance. CHEMICAL ENGINEERING JOURNAL[J]. 2023, 462: http://dx.doi.org/10.1016/j.cej.2023.142209.
[2] Jiang, Xuening, Gao, Rixia, Liu, Gang, Luo, Hao, Zhao, Xueping, Jiang, Lei. Construction of Graphene-Based "In-Paper" 3D Interdigital Microelectrodes for High Performance Metal-Free Flexible Supercapacitors. SMALL METHODS[J]. 2022, 6(5): http://dx.doi.org/10.1002/smtd.202101454.
[3] Idrees, Asim, Jiang, Xuening, Jiang, Lei, Zhang, Qingyu. Properties of composite cathodes composed of Pr3+-deficient perovskite oxide and ionic conductor Ce0.8Sm0.2O1.9. CERAMICS INTERNATIONAL[J]. 2020, 46(11): 17532-17539, http://dx.doi.org/10.1016/j.ceramint.2020.04.051.
[4] Xu, Cong, Zhang, Min, Chen, Wenwen, Jiang, Lei, Chen, Chunying, Qin, Jianhua. Assessment of Air Pollutant PM2.5 Pulmonary Exposure Using a 3D Lung-on-Chip Model. ACS BIOMATERIALS SCIENCE & ENGINEERING[J]. 2020, 6(5): 3081-3090, https://www.webofscience.com/wos/woscc/full-record/WOS:000535188500053.
[5] Su, Wentao, Yu, Hao, Jiang, Lei, Chen, Wenwen, Li, Hongjing, Qin, Jianhua. Integrated Microfluidic Device for Enrichment and Identification of Circulating Tumor Cells from the Blood of Patients with Colorectal Cancer. DISEASE MARKERS[J]. 2019, 2019: https://doaj.org/article/efaae9ffb2f747dd8661d9a604243232.
[6] Idrees, Asim, Jiang, Xuening, Liu, Gang, Luo, Hao, Zhang, Qingyu, Jiang, Lei, Li, Xiannan, Xu, Baomin. An optimized synthesis route for high performance composite cathode based on a layered perovskite oxide of PrBa0.92CO2O6-delta with cationic deficiency. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY[J]. 2019, 44(8): 4271-4280, http://cas-ir.dicp.ac.cn/handle/321008/166138.
[7] Liu, Hui, Wang, Yaqing, Chen, Wenwen, Yu, Yue, Jiang, Lei, Qin, Jianhua. A microfluidic strategy to fabricate ultra-thin polyelectrolyte hollow microfibers as 3D cellular carriers. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS[J]. 2019, 104: 109705-, http://dx.doi.org/10.1016/j.msec.2019.04.084.
[8] Liu, Hui, Wang, Yaqing, Yu, Yue, Chen, Wenwen, Jiang, Lei, Qin, Jianhua. Simple fabrication of inner chitosan-coated alginate hollow microfiber with higher stability. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS[J]. 2019, 107(8): 2527-2536, https://www.webofscience.com/wos/woscc/full-record/WOS:000488626300008.
[9] Li, Zhongyu, Jiang, Lei, Zhu, Yujuan, Su, Wentao, Xu, Cong, Tao, Tingting, Shi, Yang, Qin, Jianhua. Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice. TOXICOLOGY IN VITRO[J]. 2018, 46: 1-8, http://cas-ir.dicp.ac.cn/handle/321008/168478.
[10] Wang, Yaqing, Su, Wentao, Wang, Li, Jiang, Lei, Liu, Yang, Hui, Lijian, Qin, Jianhua. Paper supported long-term 3D liver co-culture model for the assessment of hepatotoxic drugs. TOXICOLOGY RESEARCH[J]. 2018, 7(1): 13-21, http://cas-ir.dicp.ac.cn/handle/321008/169176.
[11] Liu, HaiTao, Wang, Hui, Wei, WenBo, Liu, Hui, Jiang, Lei, Qin, JianHua. A Microfluidic Strategy for Controllable Generation of Water-in-Water Droplets as Biocompatible Microcarriers. SMALL[J]. 2018, 14(36): https://www.webofscience.com/wos/woscc/full-record/WOS:000443812600006.
[12] Zhang, Min, Xu, Cong, Jiang, Lei, Qin, Jianhua. A 3D human lung-on-a-chip model for nanotoxicity testing. TOXICOLOGY RESEARCH[J]. 2018, 7(6): http://cas-ir.dicp.ac.cn/handle/321008/166782.
[13] Idrees, Asim, Jiang, Xuening, Liu, Gang, Luo, Hao, Jia, Guoqiang, Zhang, Ngyu, Jiang, Lei, Li, Xiangnan, Xu, Baomin. Structures and Properties of LaFe0.8Cu0.2O3-delta and BaFe0.8Cu0.2O3-delta as Cobalt-Free Perovskite-Type Cathode Materials for the Oxygen Reduction Reaction. CHEMISTRYOPEN[J]. 2018, 7(9): 688-695, http://cas-ir.dicp.ac.cn/handle/321008/166814.
[14] Li, Zhongyu, Jiang, Lei, Tao, Tingting, Su, Wentao, Guo, Yaqiong, Yu, Hao, Qin, Jianhua. Assessment of cadmium-induced nephrotoxicity using a kidney-on-a-chip device. TOXICOLOGY RESEARCH[J]. 2017, 6(3): 372-380, [15] Xu, Cong, Wang, Li, Yu, Yue, Yin, Fangchao, Zhang, Xiaoqing, Jiang, Lei, Qin, Jianhua. Bioinspired onion epithelium-like structure promotes the maturation of cardiomyocytes derived from human pluripotent stem cells. BIOMATERIALS SCIENCE[J]. 2017, 5(9): 1810-1819, http://cas-ir.dicp.ac.cn/handle/321008/149878.
[16] Jiang, Xuening, Wang, Jiao, Jia, Guoqiang, Qie, Zijian, Shi, Yuchao, Idrees, Asim, Zhang, Qingyu, Jiang, Lei. Characterization of PrBa0.92CoCuO6-delta as a potential cathode material of intermediate-temperature solid oxide fuel cell. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY[J]. 2017, 42(9): 6281-6289, https://www.webofscience.com/wos/woscc/full-record/WOS:000399507100066.
[17] Tao, Shengyang, Ding, Yunzhe, Jiang, Lei, Li, Guangtao. Preparation of magnetic hierarchically porous microspheres with temperature-controlled wettability for removal of oils. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2017, 492: 73-80, http://cas-ir.dicp.ac.cn/handle/321008/169480.
[18] Zhu, Yujuan, Wang, Li, Yu, Hao, Yin, Fangchao, Wang, Yaqing, Liu, Haitao, Jiang, Lei, Qin, Jianhua. In situ generation of human brain organoids on a micropillar array. LAB ON A CHIP[J]. 2017, 17(17): 2941-2950, http://cas-ir.dicp.ac.cn/handle/321008/149845.
[19] Xu, Hui, Li, Zhongyu, Yu, Yue, Sizdahkhani, Saman, Ho, Winson S, Yin, Fangchao, Wang, Li, Zhu, Guoli, Zhang, Min, Jiang, Lei, Zhuang, Zhengping, Qin, Jianhua. A dynamic in vivo-like organotypic blood-brain barrier model to probe metastatic brain tumors. SCIENTIFIC REPORTS[J]. 2016, 6: http://cas-ir.dicp.ac.cn/handle/321008/169826.
[20] 朱国丽, 尹方超, 王丽, 张敏, 姜雷, 秦建华. 基于微流控芯片的高糖对模式生物线虫寿命影响及白藜芦醇苷保护性作用考察. 色谱[J]. 2016, 34(2): 140-145, http://lib.cqvip.com/Qikan/Article/Detail?id=667923657.
[21] Zhu, Guoli, Yin, Fangchao, Wang, Li, Wei, Wenbo, Jiang, Lei, Qin, Jianhua. Modeling type 2 diabetes-like hyperglycemia in C-elegans on a microdevice. INTEGRATIVE BIOLOGY[J]. 2016, 8(1): 30-38, http://cas-ir.dicp.ac.cn/handle/321008/171492.
[22] 苏文涛, 姜雷, 秦建华. Y-SHORT TANDEM REPEAT TYPING USING LOW COST MICROFLUIDIC SYSTEM. 31st international symposium on microscale bioseparationsnull. 2015, http://cas-ir.dicp.ac.cn/handle/321008/143450.
[23] Shi, Yang, Ma, Jingyun, Zhang, Xu, Li, Hongjing, Jiang, Lei, Qin, Jianhua. Hypoxia combined with spheroid culture improves cartilage specific function in chondrocytes. INTEGRATIVE BIOLOGY[J]. 2015, 7(3): 289-297, http://cas-ir.dicp.ac.cn/handle/321008/146106.
[24] Wen, Hui, Yu, Yue, Zhu, Guoli, Jiang, Lei, Qin, Jianhua. A droplet microchip with substance exchange capability for the developmental study of C-elegans. LAB ON A CHIP[J]. 2015, 15(8): 1905-1911, http://cas-ir.dicp.ac.cn/handle/321008/146152.
[25] Su, Wentao, Gao, Xinghua, Jiang, Lei, Qin, Jianhua. Microfluidic platform towards point-of-care diagnostics in infectious diseases. JOURNAL OF CHROMATOGRAPHY A[J]. 2015, 1377: 13-26, http://dx.doi.org/10.1016/j.chroma.2014.12.041.
[26] 苏文涛, 姜雷, 秦建华. ON-CHIP DNA PURIFICATION FROM WHOLE BLOOD SAMPLE. 31st international symposium on microscale bioseparationsnull. 2015, http://cas-ir.dicp.ac.cn/handle/321008/143451.
[27] Jiang, Xuening, Shi, Yuchao, Zhou, Wenlong, Li, Xiangnan, Su, Zhixian, Pang, Shengli, Jiang, Lei. Effects of Pr3+-deficiency on structure and properties of PrBaCo2O5+delta cathode material-A comparison with Ba2+-deficiency case. JOURNAL OF POWER SOURCES[J]. 2014, 272: 371-377, http://dx.doi.org/10.1016/j.jpowsour.2014.08.091.
[28] 温慧, 于跃, 朱国丽, 姜雷, 秦建华. DropletChip: A Scalable Bioprocessor for Long-term Study of Post-embryonic Development in Caenorhabditis elegans. the 18th international conference on miniaturized systems for chemistry and life sciencesnull. 2014, http://cas-ir.dicp.ac.cn/handle/321008/143663.
[29] 石杨, 马静云, 张旭, HongjingLi, 姜雷, 秦建华. Hypoxia Combined with Spheroid Culture in Concave Microwells Promotes Maintenance of Articular Chondrocyte Phenotype and Function. lab on a chip industry workshop- microfluidic applicationsnull. 2014, http://cas-ir.dicp.ac.cn/handle/321008/143509.
[30] Li, Xiangnan, Jiang, Xuening, Xu, Hongxia, Xu, Qiuli, Jiang, Lei, Shi, Yuchao, Zhang, Qingyu. Scandium-doped PrBaCo2-xScxO6-delta oxides as cathode material for intermediate-temperature solid oxide fuel cells. INTERNATIONAL JOURNAL OF HYDROGEN ENERGY[J]. 2013, 38(27): 12035-12042, http://159.226.238.44/handle/321008/137652.
[31] Jiang, Xuening, Xu, Hongxia, Wang, Qian, Jiang, Lei, Li, Xiangnan, Xu, Qiuli, Shi, Yuchao, Zhang, Qingyu. Fabrication of GdBaCo2O5+delta cathode using electrospun composite nanofibers and its improved electrochemical performance. JOURNAL OF ALLOYS AND COMPOUNDS[J]. 2013, 557: 184-189, http://159.226.238.44/handle/321008/137845.
[32] 马静云, 姜雷, 秦建华. Synthesis of Hollow Titania Microspheres by Using Microfluidic Droplet Template. 第三届国际微纳流控学进展学术会议null. 2012, 90-, http://159.226.238.44/handle/321008/117167.
[33] 张旭, 高兴华, 姜雷, 秦建华. Microfluidic Based Approach to Generate Gradient Electrospinning Nanofibers. 第三届国际微纳流控学进展学术会议null. 2012, 92-, http://159.226.238.44/handle/321008/117166.
[34] Jiang, Lei, Zhang, Min, Li, Jiaxing, Wen, Weijia, Qin, Jianhua. Simple Localization of Nanofiber Scaffolds via SU-8 Photoresist and Their Use for Parallel 3D Cellular Assays. ADVANCED MATERIALS[J]. 2012, 24(16): 2191-2195, http://www.irgrid.ac.cn/handle/1471x/721727.
[35] Zhang, Xu, Gao, Xinghua, Jiang, Lei, Qin, Jianhua. Flexible Generation of Gradient Electrospinning Nanofibers Using a Microfluidic Assisted Approach. LANGMUIR[J]. 2012, 28(26): 10026-10032, http://www.irgrid.ac.cn/handle/1471x/721381.
[36] Zhang, Xu, Gao, Xinghua, Jiang, Lei, Zhang, Xulang, Qin, Jianhua. Nanofiber-modified surface directed cell migration and orientation in microsystem. BIOMICROFLUIDICS[J]. 2011, 5(3): 032007-032007-10, http://www.irgrid.ac.cn/handle/1471x/456657.
[37] 马静云, 姜雷, 秦建华. 微流控液滴软模板制备二氧化钛中空微球. 色谱[J]. 2011, 29(9): 890-895, http://lib.cqvip.com/Qikan/Article/Detail?id=39380542.
[38] 潘小艳, 姜雷, 刘开颖, 林炳承, 秦建华. A microfluidic device integrated with multichamber polymerase chain reaction and multichannel separation for genetic analysis. ANALYTICA CHIMICA ACTA[J]. 2010, 674: 110-115, http://159.226.238.44/handle/321008/103435.
[39] Ma, Jingyun, Jiang, Lei, Pan, Xiaoyan, Ma, Huipeng, Lin, Bingcheng, Qin, Jianhua. A simple photolithography method for microfluidic device fabrication using sunlight as UV source. MICROFLUIDICS AND NANOFLUIDICS[J]. 2010, 9(6): 1247-1252, http://159.226.238.44/handle/321008/103431.
[40] Pan, Xiaoyan, Jiang, Lei, Liu, Kaiying, Lin, Bingcheng, Qin, Jianhua. A microfluidic device integrated with multichamber polymerase chain reaction and multichannel separation for genetic analysis. ANALYTICA CHIMICA ACTA[J]. 2010, 674(1): 110-115, http://dx.doi.org/10.1016/j.aca.2010.06.005.
[41] 潘小艳, 姜雷, 刘开颖, 李艳峰, 秦建华, 林炳承. A microfluidic-based platform integrated with multichamber PCR and multichannel CE for pathogen detection. 9th asian-pacific international symposium on microscale separations and analysis & 1st asian-pacific international symposium on lab-on-chipnull. 2009, 175/2-, http://159.226.238.44/handle/321008/113760.
[42] 高兴华, 姜雷, 秦建华, 林炳承. Microvalves actuated sandwich immunoassay on an integrated microfluidic system. advances in microfluidics and nanofluidicsnull. 2009, 135/3-, http://159.226.238.44/handle/321008/113482.
[43] Li, Bowei, Jiang, Lei, Xie, Hua, Gao, Yan, Qin, Jianhua, Lin, Bingcheng. Development of micropump-actuated negative pressure pinched injection for parallel electrophoresis on array microfluidic chip. ELECTROPHORESIS[J]. 2009, 30(17): 3053-3057, http://159.226.238.44/handle/321008/102071.
[44] 姜雷, 秦建华, 林炳承. Development of an electric-controlling focus LIF detector for microfluidic system. the 9th asian-pacific international symposium on microscale separations and analysis & the 1st asian-pacific international symposium lab-on-chipnull. 2009, 106/2-, http://159.226.238.44/handle/321008/113750.
[45] 马静云, 姜雷, 潘小艳, 秦建华, 林炳承. A simple lethography method for microfluidic chip fabrication using sunlight as UV source. the 9th asian-pacific international symposium on microscale separations and analysis & the 1st asian-pacific international symposium lab-on-chipnull. 2009, 108/2-, http://159.226.238.44/handle/321008/113752.
[46] Kong, Jing, Jiang, Lei, Su, Xiaoou, Qin, Jianhua, Du, Yuguang, Lin, Bingcheng. Integrated microfluidic immunoassay for the rapid determination of clenbuterol. LAB ON A CHIP[J]. 2009, 9(11): 1541-1547, http://159.226.238.44/handle/321008/102065.
[47] 马慧, 姜雷, 施维维, 秦建华, 林炳承. A programmable microvalve-based microfluidic array for real-time characterization of neurotoxin-induced responses of individual C. Elegans. 9th asian-pacific international symposium on microscale separations and analysis & 1st asian-pacific international symposium on lab-on-chipnull. 2009, 202/2-, http://159.226.238.44/handle/321008/113766.
[48] Lu, Yao, Shi, Weiwei, Jiang, Lei, Qin, Jianhua, Lin, Bingcheng. Rapid prototyping of paper-based microfluidics with wax for low-cost, portable bioassay. ELECTROPHORESIS[J]. 2009, 30(9): 1497-1500, http://dx.doi.org/10.1002/elps.200800563.
[49] Zhong, Runtao, Pan, Xiaoyan, Jiang, Lei, Dai, Zhongpeng, Qin, Jianhua, Lin, Bingcheng. Simply and reliably integrating micro heaters/sensors in a monolithic PCR-CE microfluidic genetic analysis system. ELECTROPHORESIS[J]. 2009, 30(8): 1297-1305, http://159.226.238.44/handle/321008/102057.
[50] Gao, Xinghua, Jiang, Lei, Su, Xiaoou, Qin, Jianhua, Lin, Bingcheng. Microvalves actuated sandwich immunoassay on an integrated microfluidic system. ELECTROPHORESIS[J]. 2009, 30(14): 2481-2487, http://dx.doi.org/10.1002/elps.200800818.
[51] Ma, Hui, Jiang, Lei, Shi, Weiwei, Qin, Jianhua, Lin, Bingcheng. A programmable microvalve-based microfluidic array for characterization of neurotoxin-induced responses of individual C. elegans. BIOMICROFLUIDICS[J]. 2009, 3(4): http://dx.doi.org/10.1063/1.3274313.
[52] Xie, Hua, Li, Bowei, Zhong, Runtao, Jiang, Lei, Zhang, Yu, Qin, Jianhua, Lin, Bingcheng. An integrated microfluidic system for rapid enzyme analysis. JOURNAL OF BIOTECHNOLOGY[J]. 2008, 136: S196-S197, http://dx.doi.org/10.1016/j.jbiotec.2008.07.1841.
[53] Li, Bowei, Jiang, Lei, Wang, Qi, Oin, Jianhua, Lin, Bingcheng. Micropumps actuated negative pressure injection for microchip electrophoresis. ELECTROPHORESIS[J]. 2008, 29(24): 4906-4913, http://159.226.238.44/handle/321008/101589.
[54] 姜雷, 秦建华, 刘兆奕, 戴忠鹏, 林炳承. 电化学检测用塑料芯片. 科技开发动态[J]. 2004, 42-42, http://lib.cqvip.com/Qikan/Article/Detail?id=11496948.
[55] 姜雷, 林炳承. Integrated Carbon Fiber Electrochemical Detector for Capillary Electrophoresis Microchips. the fifth asia-pacific international symposium on microscale separations and analysisnull. 2004, 80/1-, http://159.226.238.44/handle/321008/111648.
[56] 姜雷, 秦建华, 周小棉, 林炳承. Development of Multi-Channel Electrochemical Detection System for Microchip Electrophoresis. the fourth asia-pacific international symposium on microscale separations and analysisnull. 2002, 71/1-, http://159.226.238.44/handle/321008/111232.
[57] 姜雷, 周小棉, 秦建华, 罗勇, 戴忠鹏, 林炳承. New Electrode Configuration for Microchip Electrophoresis with Electrochemical Detection. the fourth asia-pacific international symposium on microscale separations and analysisnull. 2002, 72/1-, http://159.226.238.44/handle/321008/111234.

   

（ 1 ） 集成纳米电纺丝支架微流控芯片肾仿生模型构建及药物肾毒性评价研究, 主持, 国家级, 2016-01--2019-12