071008-发育生物学
071009-细胞生物学
0710Z1-基因组学

发育生物学
生殖生物学
基因组学

2013-08--2018-06   犹他大学医学院   博士
2009-09--2013-07   北京大学生命科学学院   理学学士

   

2021-12~现在, 中国科学院动物研究所, 研究员
2020-07~2021-11,犹他大学医学院, 助理教授
2018-08~2020-07,犹他大学医学院, 博士后

   

[1] Xichen Nie, Sarah K Munyoki, Meena Sukhwani, Nina Schmid, Annika Missel, Benjamin R Emery, DonorConnect, JanBernd Stukenborg, Artur Mayerhofer, Kyle E Orwig, Kenneth I Aston, James M Hotaling, Bradley R Cairns, Jingtao Guo. Single-cell analysis of human testis aging and correlation with elevated body mass index. Developmental Cell[J]. 2022, 57(9): 1160-1176.e5, https://doi.org/10.1016/j.devcel.2022.04.004.
[2] Grow, Edward J, Weaver, Bradley D, Smith, Christina M, Guo, Jingtao, Stein, Paula, Shadle, Sean C, Hendrickson, Peter G, Johnson, Nicholas E, Butterfield, Russell J, Menafra, Roberta, Kloet, Susan L, van der Maarel, Silvere M, Williams, Carmen J, Cairns, Bradley R. p53 convergently activates Dux/DUX4 in embryonic stem cells and in facioscapulohumeral muscular dystrophy cell models. NATURE GENETICS[J]. 2021, 53(8): 1207-1220, http://dx.doi.org/10.1038/s41588-021-00893-0.
[3] Guo, Jingtao, Sosa, Enrique, Chitiashvili, Tsotne, Nie, Xichen, Rojas, Ernesto Javier, Oliver, Elizabeth, Plath, Kathrin, Hotaling, James M, Stukenborg, JanBernd, Clark, Amander T, Cairns, Bradley R, DonorConnect. Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment. CELL STEM CELL[J]. 2021, 28(4): 764-778, http://dx.doi.org/10.1016/j.stem.2020.12.004.
[4] Mahyari, Eisa, Guo, Jingtao, Lima, Ana C, Lewinsohn, Daniel P, Stendahl, Alexandra M, VighConrad, Katinka A, Nie, Xichen, Nagirnaja, Liina, Rockweiler, Nicole B, Carrell, Douglas T, Hotaling, James M, Aston, Kenneth, I, Conrad, Donald F. Comparative single-cell analysis of biopsies clarifies pathogenic mechanisms in Klinefelter syndrome. AMERICAN JOURNAL OF HUMAN GENETICS[J]. 2021, 108(10): 1924-1945, http://dx.doi.org/10.1016/j.ajhg.2021.09.001.
[5] Guo, Jingtao, Nie, Xichen, Giebler, Maria, Mlcochova, Hana, Wang, Yueqi, Grow, Edward J, DonorConnect, Kim, Robin, Tharmalingam, Melissa, Matilionyte, Gabriele, Lindskog, Cecilia, Carrell, Douglas T, Mitchell, Rod T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R. The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty. CELL STEM CELL[J]. 2020, 26(2): 262-276, http://dx.doi.org/10.1016/j.stem.2019.12.005.
[6] Patrick J Murphy, Jingtao Guo, Timothy G Jenkins, Emma R James, John R Hoidal, Thomas Huecksteadt, Dallin S Broberg, James M Hotaling, David F Alonso, Douglas T Carrell, Bradley R Cairns, Kenneth I Aston. NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure. PLOS GENETICS[J]. 2020, 16(6): https://doaj.org/article/f1c39d09b6eb4aa9abd6df5fcde7696e.
[7] Guo Jingtao. Isolation and Enrichment of Spermatogonial Stem Cells from Human Testis Tissues. Current Protocols in Stem Cell Biology. 2019, [8] Guo, Jingtao, Grow, Edward J, Mlcochova, Hana, Maher, Geoffrey J, Lindskog, Cecilia, Nie, Xichen, Guo, Yixuan, Takei, Yodai, Yun, Jina, Cai, Long, Kim, Robin, Carrell, Douglas T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R. The adult human testis transcriptional cell atlas. CELL RESEARCH[J]. 2018, 28(12): 1141-1157, http://lib.cqvip.com/Qikan/Article/Detail?id=6100228435.
[9] Guo, Jingtao, Grow, Edward J, Yi, Chongil, Mlcochova, Hana, Maher, Geoffrey J, Lindskog, Cecilia, Murphy, Patrick J, Wike, Candice L, Carrell, Douglas T, Goriely, Anne, Hotaling, James M, Cairns, Bradley R. Chromatin and Single-Cell RNA- Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development. CELL STEM CELL[J]. 2017, 21(4): 533-+, http://dx.doi.org/10.1016/j.stem.2017.09.003.

（1） The Potential of CRISPR/Cas Gene Editing to Correct Male Infertility, Springer, 2020-03, 第 2 作者