基本信息
胡宝洋 男 博导 动物研究所
电子邮件:byhu@ioz.ac.cn
通信地址:北京市朝阳区北辰西路1号院5号C107
邮政编码:100101

研究领域

   

招生信息

   
招生专业
071009-细胞生物学
071008-发育生物学
071006-神经生物学
招生方向
干细胞与再生医学
神经干细胞与神经修复
干细胞生物学

教育背景

1999-07--2004-07 复旦大学 博士
1990-07--1995-07 济宁医学院 学士

工作经历

   
工作简历
2011-02--今 中国科学院动物研究所 研究员
2009-04--2010-09 University of Wisconsin-Madison Assistant Scientist
2005-10--2009-03 University of Wisconsin-Madison Research Associate
2004-07--2005-10 济宁医学院 教师
1995-07--1999-07 济宁医学院 教师

教授课程

干细胞研究进展系列讲座

专利与奖励

   

出版信息

   
发表论文
(1) One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system,One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system,Cell Research,2015,第5作者
(2) Human-derived neural progenitors functionally replace astrocytes in adult mice,Human-derived neural progenitors functionally replace astrocytes in adult mice,J Clin Invest,2015,第5作者
(3) Rapid and Efficient Assembly of Transcription Activator-Like Effector Genes by USER Cloning,Rapid and Efficient Assembly of Transcription Activator-Like Effector Genes by USER Cloning,Journal of Genetics and Genomics,2014,通讯作者
(4) Induced pluripotency for translational research,Induced pluripotency for translational research,Genomics Proteomics Bioinformatics,2013,通讯作者
(5) Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.,Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.,Cell Stem Cell,2012,第2作者
(6) Specification of functional neurons and glia from human pluripotent stem cells.,Specification of functional neurons and glia from human pluripotent stem cells.,Protein Cell,2012,通讯作者
(7) Directed differentiation of neural-stem cells and subtype-specific neurons from hESCs.,Directed differentiation of neural-stem cells and subtype-specific neurons from hESCs.,Methods Mol Biol.,2010,第1作者
(8) Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency.,Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency.,Proc Natl Acad Sci U S A.,2010,第1作者
(9) Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines. ,Cre recombination-mediated cassette exchange for building versatile transgenic human embryonic stem cells lines.,Stem Cells,2009,第2作者
(10) Differentiation of spinal motor neurons from pluripotent human stem cells.,Differentiation of spinal motor neurons from pluripotent human stem cells.,Nat Protoc.,2009,第1作者
(11) Differentiation of human oligodendrocytes from pluripotent stem cells.,Differentiation of human oligodendrocytes from pluripotent stem cells.,Nat Protoc.,2009,第1作者
(12) Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules.,Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules.,Stem Cells,2008,第2作者
(13) Acute photoreceptor degeneration down-regulates melanopsin expression in adult rat retina.,Acute photoreceptor degeneration down-regulates melanopsin expression in adult rat retina.,Neurosci Lett.,2006,第3作者
发表著作
(1) 新生物学年鉴2013,Advances in Biology 2013,科学出版社,2014-01,第1作者
(2) 分子生物学方法-编程与重编程章节:神经特定细胞类型定向分化,Directed differentiation of neural and subtype specific neuronal cells from hESCs. in Reprogramming and Programming of Cell Fate, Methods in Molecular Biology,Humana Press.,2009-07,第1作者
(3) 人胚干细胞实用手册章节:人胚干细胞和运动神经元定向分化,Differentiation of human embryonic stem cells into spinal motor neurons, in Human Embryonic Stem Cells: The Practical Handbook,Wiley Publishing,2007-07,第1作者
(4) 医学发育生物学章节:中枢神经系统发育,Development of Central Nervous System, in Developmental Neurobiology,科学出版社,2004-07,第1作者

科研活动

   
科研项目
(1) 人特异性miRNA-F1对人脑发育调控研究,主持,国家级,2015-01--2019-12
(2) 体外定向分化神经干细胞移植及功能整合,参与,国家级,2014-01--2018-12
(3) 神经外胚层细胞R-C化和D-V化的调控网络,主持,国家级,2012-12--2016-12
(4) 人多能干细胞分化神经细胞移植的免疫耐受诱导,主持,院级级,2012-08--2015-12
(5) 干细胞与神经再生,主持,院级级,2012-07--2015-06
(6) 人多能干细胞来源OLIG2+前体细胞向运动神经元的分化调控,主持,国家级,2012-01--2015-12
(7) 灵长类ES和iPS细胞分化为多巴胺神经细胞,参与,国家级,2012-01--2016-12
(8) 干细胞医学转化研究,主持,院级级,2011-02--2013-02
参与会议
   

合作情况

   
项目协作单位
   

指导学生

已指导学生

曹旭  硕士研究生  085238-生物工程  

现指导学生

王崧  博士研究生  071008-发育生物学  

蒋远  博士研究生  071008-发育生物学  

陈桂来  博士研究生  071008-发育生物学  

杨亚明  硕士研究生  071008-发育生物学  

丁德文  博士研究生  071008-发育生物学  

王毅  博士研究生  071008-发育生物学  

吴孟华  博士研究生  071008-发育生物学  

夏隆阔  硕士研究生  071008-发育生物学  

朱文亮  博士研究生  071008-发育生物学  

莫凡  硕士研究生  071008-发育生物学