071021-生物信息学
071023-计算生物学
071022-基因组学

生物信息学；
系统生物学
病毒分子进化；

   

[1] Chen, Ping, Wang, Jingfang, Xu, Xintian, Li, Yuping, Zhu, Yan, Li, Xuan, Li, Ming, Hao, Pei. Molecular dynamic simulation analysis of SARS-CoV-2 spike mutations and evaluation of ACE2 from pets and wild animals for infection risk. COMPUTATIONAL BIOLOGY AND CHEMISTRY[J]. 2022, 96: http://dx.doi.org/10.1016/j.compbiolchem.2021.107613.
[2] Tang, Guiyue, Xie, Bingran, Hong, Xiangna, Qin, Hang, Wang, Jingfang, Huang, Hai, Hao, Pei, Li, Xuan. Creating RNA Specific C-to-U Editase from APOBEC3A by Separation of Its Activities on DNA and RNA Substrates. ACS SYNTHETIC BIOLOGY[J]. 2021, 10(5): 1106-1115, http://dx.doi.org/10.1021/acssynbio.0c00627.
[3] Chen, Zechuan, Yang, Zeruo, Yuan, Xiaojun, Zhang, Xiaoming, Hao, Pei. scSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy. BMC BIOINFORMATICS[J]. 2021, 22(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063398/.
[4] Hao, Pei, Zhong, Wu, Song, Shiyang, Fan, Shiyong, Li, Xuan. Is SARS-CoV-2 originated from laboratory? A rebuttal to the claim of formation via laboratory recombination. EMERGING MICROBES & INFECTIONSnull. 2020, 9(1): 545-547, https://www.webofscience.com/wos/woscc/full-record/WOS:000519043200001.
[5] Xu, Xintian, Chen, Ping, Wang, Jingfang, Feng, Jiannan, Zhou, Hui, Li, Xuan, Zhong, Wu, Hao, Pei. Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. SCIENCE CHINA-LIFE SCIENCES[J]. 2020, 63(3): 457-460, http://lib.cqvip.com/Qikan/Article/Detail?id=7101235361.
[6] Yuan, Jie, Chang, SiYuan, Yin, ShiGang, Liu, ZhiYang, Cheng, Xiu, Liu, XiJuan, Jiang, Qiang, Gao, Ge, Lin, DeYing, Kang, XinLei, Ye, ShiWei, Chen, Zheng, Yin, JiangAn, Hao, Pei, Jiang, Lubin, Cai, ShiQing. Two conserved epigenetic regulators prevent healthy ageing. NATURE[J]. 2020, 579(7797): 118-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000516702000006.
[7] Wang, Jingfang, Xu, Xintian, Zhou, Xinbo, Chen, Ping, Liang, Huiying, Li, Xuan, Zhong, Wu, Hao, Pei. Molecular simulation of SARS-CoV-2 spike protein binding to pangolin ACE2 or human ACE2 natural variants reveals altered susceptibility to infection. JOURNAL OF GENERAL VIROLOGY[J]. 2020, 101(9): 921-924, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654750/.
[8] Zhang, Niubing, Jing, Xinyun, Liu, Yuanhua, Chen, Minjie, Zhu, Xianfeng, Jiang, Jing, Wang, Hongbing, Li, Xuan, Hao, Pei. Interfering with retrotransposition by two types of CRISPR effectors: Cas12a and Cas13a. CELL DISCOVERY[J]. 2020, 6(1): https://doaj.org/article/5642b9fd1956435baaf938c39d250207.
[9] Wenhao Qian, Ting Ma, Mao Ye, Zhiyao Li, Yuanhua Liu, Pei Hao. Microbiota in the apical root canal system of tooth with apical periodontitis. BMC GENOMICS[J]. 2019, 20(S2): 175-185, https://doaj.org/article/eaf5582d58ce43f5b80463e9e5b8762e.
[10] 马婷, 黄海, 郝沛. 乙肝病毒（HBV）感染对肝细胞癌（HCC）患者A-to-I RNA编辑的影响. 复旦学报:医学版[J]. 2019, 46(6): 744-749, http://lib.cqvip.com/Qikan/Article/Detail?id=7100421788.
[11] Wu, Chunmei, Fu, Qiong, Guo, Qiang, Chen, Sheng, Goswami, Shyamal, Sun, Shuhui, Li, Teng, Cao, Xingjian, Chu, Fuying, Chen, Zechuan, Liu, Mei, Liu, Yuanhua, Fu, Ting, Hao, Pei, Hao, Yi, Shen, Nan, Bao, Chunde, Zhang, Xiaoming. Lupus-associated atypical memory B cells are mTORC1-hyperactivated and functionally dysregulated. ANNALS OF THE RHEUMATIC DISEASES[J]. 2019, 78(8): 1090-1100, https://www.webofscience.com/wos/woscc/full-record/WOS:000484452500026.
[12] Jiazi Ren, Lei Han, Jinyi Tang, Yuanhua Liu, Xiaoxue Deng, Qiuyue Liu, Pei Hao, Xiaoming Feng, Bin Li, Hui Hu, Haikun Wang. Foxp1 is critical for the maintenance of regulatory T-cell homeostasis and suppressive function.. PLOS BIOLOGY[J]. 2019, 17(5): https://doaj.org/article/c566ec49ae9a43ae9a6e3c1af4699393.
[13] Huabin Liang, Jinyi Tang, Zhihua Liu, Yuanhua Liu, Yuanyuan Huang, Yongfen Xu, Pei Hao, Zhinan Yin, Jin Zhong, Lilin Ye, Xia Jin, Haikun Wang. ZIKV infection induces robust Th1-like Tfh cell and long-term protective antibody responses in immunocompetent mice. NATURE COMMUNICATIONS[J]. 2019, 10(1): 1-16, http://dx.doi.org/10.1038/s41467-019-11754-0.
[14] Ye, Yan, Liu, Mei, Tang, Longhai, Du, Fang, Liu, Yuanhua, Hao, Pei, Fu, Qiong, Guo, Qiang, Yan, Qingran, Zhang, Xiaoming, Bao, Chunde. Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis. ARTHRITIS RESEARCH & THERAPY[J]. 2019, 21(1): https://doaj.org/article/495c723bc07a429a97b2b4178b4f42be.
[15] Wan, Xiaoling, Liu, Lulu, Zhou, Peipei, Hui, Xinhui, He, Qiaomei, Yu, Fangfang, Zhang, Wei, Ding, Xiaodan, Yuan, Xiujie, Zhang, Na, Zhao, Yingxi, Zhu, Ruihong, Liu, Yuanhua, Hao, Pei, Auwerx, Johan, Song, Xianmin, Leng, Qibin, Zhang, Yan. The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo. BLOOD ADVANCES[J]. 2019, 3(4): 644-657, http://dx.doi.org/10.1182/bloodadvances.2018022756.
[16] Xufeng Chen, Jingyao Zhao, Chan Gu, Yu Cui, Yuling Dai, Guangrong Song, Haifeng Liu, Hao Shen, Yuanhua Liu, Yuya Wang, Huayue Xing, Xiaoyan Zhu, Pei Hao, Fan Guo, Xiaolong Liu. Med23 serves as a gatekeeper of the myeloid potential of hematopoietic stem cells. NATURE COMMUNICATIONS[J]. 2018, 9(1): [17] Huang, Yaowei, Cao, Yingying, Li, Jiarui, Liu, Yuanhua, Zhong, Wu, Li, Xuan, Chen, Chen, Hao, Pei. A survey on cellular RNA editing activity in response to Candida albicans infections. BMC GENOMICS[J]. 2018, 19(S1): https://doaj.org/article/d88e8fd780a54fed97a79f7ec831bd3b.
[18] Chen, Ping, Jing, Xinyun, Ren, Jian, Cao, Han, Hao, Pei, Li, Xuan. Modelling BioNano optical data and simulation study of genome map assembly. BIOINFORMATICS[J]. 2018, 34(23): 3966-3974, http://dx.doi.org/10.1093/bioinformatics/bty456.
[19] Cao, Yingying, Cao, Ruiyuan, Huang, Yaowei, Zhou, Hongxia, Liu, Yuanhua, Li, Xuan, Zhong, Wu, Hao, Pei. A comprehensive study on cellular RNA editing activity in response to infections with different subtypes of influenza a viruses. BMC GENOMICS[J]. 2018, 19(S1): https://doaj.org/article/edcfcad20db0400b8536a7cf43771a20.
[20] Bai, Fang, Liu, Kangdong, Li, Huiliang, Wang, Jiawei, Zhu, Junsheng, Hao, Pei, Zhu, Lili, Zhang, Shoude, Shan, Lei, Ma, Weiya, Bode, Ann M, Zhang, Weidong, Li, Honglin, Dong, Zigang. Veratramine modulates AP-1-dependent gene transcription by directly binding to programmable DNA. NUCLEIC ACIDS RESEARCH[J]. 2018, 46(2): 546-557, https://www.webofscience.com/wos/woscc/full-record/WOS:000423812300011.
[21] Jing, Xinyun, Xie, Bingran, Chen, Longxian, Zhang, Niubing, Jiang, Yiyi, Qin, Hang, Wang, Hongbing, Hao, Pei, Yang, Sheng, Li, Xuan. Implementation of the CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editing. NUCLEIC ACIDS RESEARCH[J]. 2018, 46(15): http://dx.doi.org/10.1093/nar/gky433.
[22] 郝沛. The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection.. PLoS Genetics. 2017, [23] Zhang, Chao, Hua, Rui, Cui, Yuanyuan, Wang, Shasha, Yan, Hongqing, Li, Dongmei, Zhang, Yonghong, Tu, Zhengkun, Hao, Pei, Chen, Xinyue, Zhong, Jin, Niu, Junqi, Jin, Xia. Comprehensive mapping of antigen specific T cell responses in hepatitis C virus infected patients with or without spontaneous viral clearance. PLOS ONE[J]. 2017, 12(2): https://doaj.org/article/1325cf04b06046f28ec605b0c0f30240.
[24] Cao, RuiYuan, Xu, Yongfen, Zhang, TianHong, Yang, JingJing, Yuan, Ye, Hao, Pei, Shi, Yi, Zhong, Jin, Zhong, Wu. Pediatric Drug Nitazoxanide: A Potential Choice for Control of Zika. OPEN FORUM INFECTIOUS DISEASES[J]. 2017, 4(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000405678200063.
[25] Cao, Yingying, Huang, Yaowei, Xu, Ke, Liu, Yuanhua, Li, Xuan, Xu, Ye, Zhong, Wu, Hao, Pei. Differential responses of innate immunity triggered by different subtypes of influenza a viruses in human and avian hosts. BMC MEDICAL GENOMICS[J]. 2017, 10(S4): https://doaj.org/article/34a867577e214feea9781ec27be6e34e.
[26] Zhu, Yan, Chen, Longxian, Zhang, Chengjun, Hao, Pei, Jing, Xinyun, Li, Xuan. Global transcriptome analysis reveals extensive gene remodeling, alternative splicing and differential transcription profiles in non-seed vascular plant Selaginella moellendorffii. BMC GENOMICS[J]. 2017, 18(Suppl 1): http://dx.doi.org/10.1186/s12864-016-3266-1.
[27] Sun, Jin, Li, Min, Wang, Yinan, Hao, Pei, Jin, Xia. Elaboration of tetravalent antibody responses against dengue viruses using a subunit vaccine comprised of a single consensus dengue envelope sequence. VACCINE[J]. 2017, 35(46): 6308-6320, http://dx.doi.org/10.1016/j.vaccine.2017.09.063.
[28] Yu, Yao, Zhou, Hongxia, Kong, Yimeng, Pan, Bohu, Chen, Longxian, Wang, Hongbing, Hao, Pei, Li, Xuan. The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection. PLOS GENETICS[J]. 2016, 12(7): https://doaj.org/article/dae7f479175a4c70bcfe176806a99e10.
[29] Kong, Yimeng, Zhou, Hongxia, Yu, Yao, Chen, Longxian, Hao, Pei, Li, Xuan. The evolutionary landscape of intergenic trans-splicing events in insects. NATURE COMMUNICATIONS[J]. 2015, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000366297600001.
[30] Zheng, LuLu, Li, Chunyan, Ping, Jie, Zhou, Yanhong, Li, Yixue, Hao, Pei. The Domain Landscape of Virus-Host Interactomes. BIOMED RESEARCH INTERNATIONAL[J]. 2014, 2014: https://doaj.org/article/827284322de0449fb4858e472c2ff11f.
[31] Shu, Jiayi, Fan, Xiaojuan, Ping, Jie, Jin, Xia, Hao, Pei. Designing Peptide-Based HIV Vaccine for Chinese. BIOMED RESEARCH INTERNATIONAL[J]. 2014, 2014: https://doaj.org/article/e1fcfd553f444c49958bbc1506d98cb1.
[32] Yu, Yao, Li, Xuan, Hao, Pei, Wang, JingFang, Chou, KuoChen. Research/Review: Structure and Linkage Disequilibrium Analysis of Adamantane Resistant Mutations in Influenza Virus M2 Proton Channel. CURRENT DRUG METABOLISM[J]. 2014, 15(5): 526-534, http://dx.doi.org/10.2174/1389200215666140605130406.
[33] Yu, Shuhao, Zheng, Lulu, Li, Yixue, Li, Chunyan, Ma, Chenchen, Yu, Yang, Li, Xuan, Hao, Pei. Causal co-expression method with module analysis to screen drugs with specific target. GENE[J]. 2013, 518(1): 145-151, http://dx.doi.org/10.1016/j.gene.2012.11.051.
[34] Ma, LiangXiao, Wang, YaJun, Wang, JingFang, Li, Xuan, Hao, Pei. Expression Sensitivity Analysis of Human Disease Related Genes. BIOMED RESEARCH INTERNATIONAL[J]. 2013, 2013: https://doaj.org/article/65b0dbf5ac2746e1bbe8f74d5ce77624.
[35] Ping, Jie, Hao, Pei, Li, YiXue, Wang, JingFang. Molecular Dynamics Studies on the Conformational Transitions of Adenylate Kinase: A Computational Evidence for the Conformational Selection Mechanism. BIOMED RESEARCH INTERNATIONAL[J]. 2013, 2013: https://doaj.org/article/df9edd20fa25474f9af4ed2f2dc86783.
[36] Hu, Yunwen, Lu, Shuihua, Song, Zhigang, Wang, Wei, Hao, Pei, Li, Jianhua, Zhang, Xiaonan, Yen, HuiLing, Shi, Bisheng, Li, Tao, Guan, Wencai, Xu, Lei, Liu, Yi, Wang, Sen, Zhang, Xiaoling, Tian, Di, Zhu, Zhaoqin, He, Jing, Huang, Kai, Chen, Huijie, Zheng, Lulu, Li, Xuan, Ping, Jie, Kang, Bin, Xi, Xiuhong, Zha, Lijun, Li, Yixue, Zhang, Zhiyong, Peiris, Malik, Yuan, Zhenghong. Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance. LANCET[J]. 2013, 381(9885): 2273-2279, http://dx.doi.org/10.1016/S0140-6736(13)61125-3.
[37] 郝沛. Optimizing de novo transcriptome assembly from short-read RNA-Seq data: a comparative study.. BMC System Biology. 2013, [38] 郝沛. Causal co-expression method with module analysis to screen drugs with specific target.. Gene. 2012, [39] Wang, YaJun, Wang, JingFang, Ping, Jie, Yu, Yao, Wang, Ying, Lian, Peng, Li, Xuan, Li, YiXue, Hao, Pei. Computational Studies on the Substrate Interactions of Influenza A Virus PB2 Subunit. PLOS ONE[J]. 2012, 7(9): https://doaj.org/article/5513593b654140c095470666824544cd.
[40] LuLu Zheng, YiXue Li, Juan Ding, XiaoKui Guo, KaiYan Feng, YaJun Wang, LeLe Hu, YuDong Cai, Pei Hao, KuoChen Chou. A Comparison of Computational Methods for Identifying Virulence Factors. PLOS ONE[J]. 2012, 7(8): http://www.corc.org.cn/handle/1471x/2296051.
[41] Yu, Shuhao, Zheng, Lulu, Li, Yun, Li, Chunyan, Ma, Chenchen, Li, Yixue, Li, Xuan, Hao, Pei. A cross-species analysis method to analyze animal models' similarity to human's disease state. BMC SYSTEMS BIOLOGY[J]. 2012, 6(Suppl 3): S18-S18, http://dx.doi.org/10.1186/1752-0509-6-S3-S18.
[42] Ping, Jie, Wang, YaJun, Wang, JingFang, Li, Xuan, Li, YiXue, Hao, Pei. Negatively Cooperative Binding Properties of Human Cytochrome P450 2E1 with Monocyclic Substrates. CURRENT DRUG METABOLISMnull. 2012, 13(7): 1024-1031, https://www.webofscience.com/wos/woscc/full-record/WOS:000307743000017.
[43] Li, Yun, Tu, Kang, Zheng, Siyuan, Wang, Jingfang, Li, Yixue, Hao, Pei, Li, Xuan. ASSOCIATION OF FEATURE GENE EXPRESSION WITH STRUCTURAL FINGERPRINTS OF CHEMICAL COMPOUNDS. JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY[J]. 2011, 9(4): 503-519, [44] Xu, Tao, Ping, Jie, Yu, Yao, Yu, Fudong, Yu, Yongtao, Hao, Pei, Li, Xuan. Revealing parasite influence in metabolic pathways in Apicomplexa infected patients. BMC BIOINFORMATICS[J]. 2010, 11(Suppl 11): S13-S13, http://dx.doi.org/10.1186/1471-2105-11-S11-S13.
[45] Yu, Yao, Xu, Tao, Yu, Yongtao, Hao, Pei, Li, Xuan. Association of tissue lineage and gene expression: conservatively and differentially expressed genes define common and special functions of tissues. BMC BIOINFORMATICS[J]. 2010, 11(Suppl 11): S1-S1, http://dx.doi.org/10.1186/1471-2105-11-S11-S1.
[46] Yu, Yao, Ping, Jie, Chen, Hui, Jiao, Longxian, Zheng, Siyuan, Han, ZeGuang, Hao, Pei, Huang, Jian. A comparative analysis of liver transcriptome suggests divergent liver function among human, mouse and rat. GENOMICS[J]. 2010, 96(5): 281-289, http://dx.doi.org/10.1016/j.ygeno.2010.08.003.
[47] Yixue Li, Pei Hao, Jie Ping, Guohui Ding, Yun Li, Siyuan Zheng, Kang Tu, Yao Yu. GEOGLE: context mining tool for the correlation between gene expression and the phenotypic distinction. 2009, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201706289666864ZK.
[48] Zheng, Siyuan, Sheng, Jia, Wang, Chuan, Wang, Xiaojing, Yu, Yao, Li, Yun, Michie, Alex, Dai, Jianliang, Zhong, Yang, Hao, Pei, Liu, Lei, Li, Yixue. MPSQ: a web tool for protein-state searching. BIOINFORMATICS[J]. 2008, 24(20): 2412-2413, https://www.webofscience.com/wos/woscc/full-record/WOS:000259973500028.