基本信息
范克龙  男  博导  中国科学院生物物理研究所
电子邮件: fankelong@ibp.ac.cn
通信地址: 北京市朝阳区大屯路15号
邮政编码:

研究领域

研究方向为纳米酶的仿生合成及其生物医学应用。取得的主要学术成果如下:

①首次提出模拟天然酶活性中心,仿生设计纳米酶的新理念,实现高活性单原子纳米酶的设计合成。
②发明铁蛋白纳米酶:发现铁蛋白独特的新功能,识别肿瘤标志分子TfR1及穿越血脑屏障。据此,仿生设计铁蛋白纳米酶,结合铁蛋白新特性,实现纳米酶在肿瘤诊断和催化治疗领域的突破,研究成果入选中国十大科学进展。
③发现铁蛋白存在温度敏感型药物通道,突破药物装载技术瓶颈,发展了铁蛋白药物载体。

上述成果以第一/共通讯发表在Nat NanoNat CommunAngew ChemACS Nano等权威期刊,发明专利授权并转让6000万。获得贝时璋青年生物物理学家奖(2019),全国创新创业好青年(2019),中国科学院优秀博士毕业论文(2015)等奖项。



招生信息

本课题组将招收至少一位硕博连读生。欢迎对铁蛋白或纳米酶的仿生设计领域感兴趣的本科应届毕业生推免或者报考


招生专业
071010-生物化学与分子生物学
083100-生物医学工程
0703Z1-化学生物学
招生方向
纳米生物学与纳米医学
纳米酶的仿生设计
蛋白质药物载体

教育背景

2009-09--2014-07   中国科学院大学   博士
2005-09--2009-07   中国矿业大学(北京)   学士

工作经历

   
工作简历
2019-07~现在, 中国科学院生物物理研究所, 研究员
2018-02~2019-07,中国科学院生物物理研究所, 副研究员
2014-08~2018-01,中国科学院生物物理研究所, 博士后,副研究员(资格)
社会兼职
2022-05-01-今,Frontiers in Chemistry 副主编, 副主编
2021-03-31-2023-04-30,Exploration杂志, 副主编
2019-07-01-2022-07-01,中国生物物理学会纳米酶分会, 副秘书长

专利与奖励

   
奖励信息
(1) 贝时璋青年生物物理学家奖, 其他, 2019
(2) 全国向上向善好青年, 国家级, 2019
(3) 中国医师协会优秀青年科技工作者, 其他, 2019
(4) 中国科学院优秀博士学位论文, 院级, 2015
(5) 中国科学院院长特别奖, 院级, 2013
专利成果
[1] 阎锡蕴, 高利增, 范克龙, 孟祥芹. 硫铁矿纳米酶、抗肿瘤药物及应用. CN: CN112791099A, 2021-05-14.

[2] 阎锡蕴, 范克龙, 赵帅. 一种用于恶性脑疟治疗的新型试剂及方法. CN: CN111840250A, 2020-10-30.

[3] 阎锡蕴, 江冰, 范克龙. 一种用于肝癌诊断的特异性靶点及诊断试剂. CN: CN109852666A, 2019-06-07.

[4] 阎锡蕴, 范克龙, 江冰. 一种装载抗肿瘤药物的纳米药物载体、其制备方法及应用. CN: CN109512799A, 2019-03-26.

[5] 阎锡蕴, 丁辉, 范克龙, 杨明. 纳米酶小体在催化光声成像中的应用. CN: CN109364272A, 2019-02-22.

[6] 阎锡蕴, 范克龙, 高利增, 段德民. 优化纳米酶颗粒活性的方法. CN: CN108067309A, 2018-05-25.

[7] 阎锡蕴, 范克龙, 高利增, 段德民, 张德玺, 桑建彬. 一种具有止血、杀菌功能的纳米酶止血剂及其应用. CN: CN107496449A, 2017-12-22.

[8] 史桂芝, 范克龙, 张德玺, 桑建彬, 阎锡蕴. 分子标记物CD71及在子宫内膜癌诊断、分期及预后中的应用. CN: CN107102141A, 2017-08-29.

[9] 阎锡蕴, Fan Kelong, Liang Minmin, Wang Fei, Duan Demin, Zhang Dexi, Feng Jing, Yang Dongling. DRUG CARRIER FOR TUMOR-SPECIFIC TARGETED DRUG DELIVERY AND USE THEREOF. CN: US20170189343A1, 2017-07-06.

[10] 阎锡蕴, 范克龙, 梁敏敏, 郑继燕, 冯静, 杨东玲. 一种肿瘤特异性靶向给药的药物载体及其应用. CN: CN104013599A, 2014-09-03.

[11] 阎锡蕴, 梁敏敏, 范克龙, 潘永信, 曹长乾, 杨东玲, 卢迪, 冯静. 一种双功能肿瘤诊断试剂及方法. CN: CN102778567A, 2012-11-14.

出版信息

   
发表论文
[1] Wenhui Gao, Jiuyang He, Lei Chen, Xiangqin Meng, Yana Ma, Liangliang Cheng, Kangsheng Tu, Xingfa Gao, Cui Liu, Mingzhen Zhang, Kelong Fan, Dai-Wen Pang, Xiyun Yan. Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme. NATURE COMMUNICATIONS[J]. 2023, 14(1): 1-15, http://dx.doi.org/10.1038/s41467-023-35828-2.
[2] Liu, Cui, Fan, Wenbin, Cheng, WenXiang, Gu, Yiping, Chen, Yiming, Zhou, Wenhua, Yu, XueFeng, Chen, Minghai, Zhu, Minrong, Fan, Kelong, Luo, QingYing. Red Emissive Carbon Dot Superoxide Dismutase Nanozyme for Bioimaging and Ameliorating Acute Lung Injury. ADVANCED FUNCTIONAL MATERIALS[J]. 2023, [3] Wang, Zhuoran, Zhao, Yue, Hou, Yaxin, Tang, Guoheng, Zhang, Ruofei, Yang, Yili, Yan, Xiyun, Fan, Kelong. A Thrombin-Activated Peptide-Templated Nanozyme for Remedying Ischemic Stroke via Thrombolytic and Neuroprotective Actions. ADVANCED MATERIALS. 2023, http://dx.doi.org/10.1002/adma.202210144.
[4] Zhang, Baoli, Chen, Xuehui, Tang, Guoheng, Zhang, Ruofei, Li, Jingyun, Sun, Guoming, Yan, Xiyun, Fan, Kelong. Constructing a nanocage-based universal carrier for delivering TLR- activating nucleic acids to enhance antitumor immunotherapy. NANO TODAY[J]. 2022, 46: http://dx.doi.org/10.1016/j.nantod.2022.101564.
[5] Pang, Jing, Feng, Xu, Liang, Qian, Zheng, Xiaoyan, Duan, Yiman, Zhang, Xin, Zhang, Jubiao, Chen, Yang, Fan, Kelong, Gao, Lizeng, Li, Juxue. Ferritin-Nanocaged ATP Traverses the Blood-Testis Barrier and Enhances Sperm Motility in an Asthenozoospermia Model. ACS NANO[J]. 2022, 16(3): 4175-4185, http://dx.doi.org/10.1021/acsnano.1c10029.
[6] Jiang, Bing, Jia, Xiaohua, Ji, Tianjiao, Zhou, Meng, He, Jiuyang, Wang, Kun, Tian, Jie, Yan, Xiyun, Fan, Kelong. Ferritin nanocages for early theranostics of tumors via inflammation-enhanced active targeting. SCIENCE CHINA-LIFE SCIENCES[J]. 2022, 65(2): 328-340, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000693359700004.
[7] Zhang, Ruofei, Xue, Bai, Tao, Yanhong, Zhao, Hanqing, Zhang, Zixia, Wang, Xiaonan, Zhou, Xinyao, Jiang, Bing, Yang, Zhenglin, Yan, Xiyun, Fan, Kelong. Edge-Site Engineering of Defective Fe-N-4 Nanozymes with Boosted Catalase-Like Performance for Retinal Vasculopathies. ADVANCED MATERIALS[J]. 2022, 34(39): http://dx.doi.org/10.1002/adma.202205324.
[8] Zhu, Daoming, Chen, Hao, Huang, Chunyu, Li, Guoxin, Wang, Xing, Jiang, Wei, Fan, Kelong. H2O2 Self-Producing Single-Atom Nanozyme Hydrogels as Light-Controlled Oxidative Stress Amplifier for Enhanced Synergistic Therapy by Transforming "Cold" Tumors. ADVANCED FUNCTIONAL MATERIALS[J]. 2022, 32(16): http://dx.doi.org/10.1002/adfm.202110268.
[9] 范克龙, 魏辉, 许华平, 王树涛, 曲晓刚, 张灿. 生物活性纳米材料用于重大疾病治疗的研究进展. 中国基础科学[J]. 2022, 57-67, http://lib.cqvip.com/Qikan/Article/Detail?id=00002EGM55987JP0MLDO8JP1MDR.
[10] Hong, Chaoyi, Meng, Xiangqin, He, Jiuyang, Fan, Kelong, Yan, Xiyun. Nanozyme: A promising tool from clinical diagnosis and environmental monitoring to wastewater treatment. PARTICUOLOGYnull. 2022, 71(12): 90-107, http://dx.doi.org/10.1016/j.partic.2022.02.001.
[11] 谢佳颖, 金奕良, 范克龙. 铁蛋白:疫苗设计新平台. 科学. 2022, 74(4): 44-48, http://lib.cqvip.com/Qikan/Article/Detail?id=7107917611.
[12] Zhang, Shuai, Zhang, Ruofei, Yan, Xiyun, Fan, Kelong. Nanozyme-Based Artificial Organelles: An Emerging Direction for Artificial Organelles. SMALLnull. 2022, 18(33): http://dx.doi.org/10.1002/smll.202202294.
[13] Meng, Xiangqin, Li, Dandan, Chen, Lei, He, Helen, Wang, Qian, Hong, Chaoyi, He, Jiuyang, Gao, Xingfa, Yang, Yili, Jiang, Bing, Nie, Guohui, Yan, Xiyun, Gao, Lizeng, Fan, Kelong. High-Performance Self-Cascade Pyrite Nanozymes for Apoptosis-Ferroptosis Synergistic Tumor Therapy. ACS NANO[J]. 2021, 15(3): 5735-5751, http://dx.doi.org/10.1021/acsnano.1c01248.
[14] Xi, Juqun, Zhang, Ruofei, Wang, Liming, Xu, Wei, Liang, Qian, Li, Jingyun, Jiang, Jian, Yang, Yili, Yan, Xiyun, Fan, Kelong, Gao, Lizeng. A Nanozyme-Based Artificial Peroxisome Ameliorates Hyperuricemia and Ischemic Stroke. ADVANCED FUNCTIONAL MATERIALS[J]. 2021, 31(9): http://dx.doi.org/10.1002/adfm.202007130.
[15] Zeng, Li, Cheng, Hui, Dai, Yuwei, Su, Zhipeng, Wang, Chengde, Lei, Lei, Lin, Deqing, Li, Xingyi, Chen, Hao, Fan, Kelong, Shi, Shuai. In Vivo Regenerable Cerium Oxide Nanozyme-Loaded pH/H2O2-Responsive Nanovesicle for Tumor-Targeted Photothermal and Photodynamic Therapies. ACS APPLIED MATERIALS & INTERFACES[J]. 2021, 13(1): 233-244, https://www.webofscience.com/wos/woscc/full-record/WOS:000611066000018.
[16] Wang, Daji, Zhang, Bin, Ding, Hui, Liu, Dan, Xiang, Jianquan, Gao, Xuejiao J, Chen, Xuehui, Li, Zhongjun, Yang, Lei, Duan, Hongxia, Zheng, Jiyan, Liu, Zheng, Jiang, Bing, Liu, Yang, Xie, Ni, Zhang, Han, Yan, Xiyun, Fan, Kelong, Nie, Guohui. TiO2 supported single Ag atoms nanozyme for elimination of SARS-CoV2. NANO TODAY[J]. 2021, 40: 101243-101243, http://dx.doi.org/10.1016/j.nantod.2021.101243.
[17] Wu, Chunling, Shi, Huigang, Zhu, Dongjie, Fan, Kelong, Zhang, Xinzheng. Low-cooling-rate freezing in biomolecular cryo-electron microscopy for recovery of initial frames. QRB Discovery[J]. 2021, [18] 向建全, 周彩玉, 张若飞, 曾凡才, 范克龙. 铁蛋白装载“铁-阿霉素”新策略. 中国科学:生命科学[J]. 2021, 51(7): 871-878, https://www.sciengine.com/doi/10.1360/SSV-2021-0134.
[19] Zhang, Yanan, Li, Yingni, Zhang, Jianlin, Chen, Xuehui, Zhang, Ruofei, Sun, Guoming, Jiang, Bing, Fan, Kelong, Li, Zhanguo, Yan, Xiyun. Nanocage-Based Capture-Detection System for the Clinical Diagnosis of Autoimmune Disease. SMALL[J]. 2021, 17(25): http://dx.doi.org/10.1002/smll.202101655.
[20] Jiang, Bing, Jia, Xiaohua, Ji, Tianjiao, Zhou, Meng, He, Jiuyang, Wang, Kun, Tian, Jie, Yan, Xiyun, Fan, Kelong. Ferritin nanocages for early theranostics of tumors via inflammation-enhanced active targeting. SCIENCE CHINA-LIFE SCIENCES[J]. 2021, 65: 13-, https://www.sciengine.com/doi/10.1007/s11427-021-1976-0.
[21] Fan, Kelong, Lin, Youhui, Bansal, Vipul. Editorial: Nanozymes: From Rational Design to Biomedical Applications. FRONTIERS IN CHEMISTRY[J]. 2021, 9: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042218/.
[22] Wang, Zhuoran, Zhang, Shuai, Zhang, Ruofei, Chen, Xuehui, Sun, Guoming, Zhou, Meng, Han, Qiubai, Zhang, Baoli, Zhao, Yue, Jiang, Bing, Yang, Yili, Yan, Xiyun, Fan, Kelong. Bioengineered Dual-Targeting Protein Nanocage for Stereoscopically Loading of Synergistic Hydrophilic/Hydrophobic Drugs to Enhance Anticancer Efficacy. ADVANCED FUNCTIONAL MATERIALS[J]. 2021, 31(29): http://dx.doi.org/10.1002/adfm.202102004.
[23] 赵越, 孟祥芹, 阎锡蕴, 范克龙. 纳米酶:一种新型的生物安全材料. 应用化学[J]. 2021, 38(5): 524-545, http://lib.cqvip.com/Qikan/Article/Detail?id=00002EKD593O7JP0MNDO4JP1MDR.
[24] 焦健, 范克龙, 胡志刚, 杜鹏. 纳米生物学的研究现状与关键科学问题. 中国科学:生命科学[J]. 2020, 50(7): 778-787, https://www.sciengine.com/doi/10.1360/SSV-2019-0296.
[25] Zhang, Ruofei, Fan, Kelong, Yan, Xiyun. Nanozymes: created by learning from nature. SCIENCE CHINA-LIFE SCIENCES[J]. 2020, 63(8): 1183-1200, http://lib.cqvip.com/Qikan/Article/Detail?id=7102433154.
[26] Liang, Qian, Xi, Juqun, Gao, Xuejiao J, Zhang, Ruofei, Yang, Yili, Gao, Xingfa, Yan, Xiyun, Gao, Lizeng, Fan, Kelong. A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy. NANO TODAY[J]. 2020, 35: http://dx.doi.org/10.1016/j.nantod.2020.100935.
[27] Jiaying Xie, Yiliang Jin, Kelong Fan, Xiyun Yan. The prototypes of nanozyme-based nanorobots. 生物物理学报:英文版[J]. 2020, 6(6): 223-244, http://lib.cqvip.com/Qikan/Article/Detail?id=7103702509.
[28] 侯亚欣, 张若飞, 阎锡蕴, 范克龙. 纳米酶:疾病治疗新选择. 中国科学:生命科学[J]. 2020, 50(3): 311-328, https://www.sciengine.com/doi/10.1360/SSV-2019-0216.
[29] Zhu, Daoming, Lyu, Meng, Huang, Qinqin, Suo, Meng, Liu, Ying, Jiang, Wei, Duo, Yanhong, Fan, Kelong. Stellate Plasmonic Exosomes for Penetrative Targeting Tumor NIR-II Thermo-Radiotherapy. ACS APPLIED MATERIALS & INTERFACES[J]. 2020, 12(33): 36928-36937, https://www.webofscience.com/wos/woscc/full-record/WOS:000563074900011.
[30] Yang, Yang, Zhu, Daoming, Liu, Ying, Jiang, Bing, Jiang, Wei, Yan, Xiyun, Fan, Kelong. Platinum-carbon-integrated nanozymes for enhanced tumor photodynamic and photothermal therapy. NANOSCALE[J]. 2020, 12(25): 13548-13557, http://dx.doi.org/10.1039/d0nr02800b.
[31] Jiang, Bing, Chen, Xuehui, Sun, Guoming, Chen, Xiangru, Yin, Yufang, Jin, Yiliang, Mi, Qian, Ma, Long, Yang, Yili, Yan, Xiyun, Fan, Kelong. A natural drug entry channel in the ferritin nanocage. NANO TODAY[J]. 2020, 35: http://dx.doi.org/10.1016/j.nantod.2020.100948.
[32] Jia, Xiaohua, Fan, Kelong, Zhang, Ruofei, Zhang, Dan, Zhang, Jianjun, Gao, Yuan, Zhang, Tao, Li, Wanjun, Li, Junlai, Yan, Xiyun, Tian, Jie. Precise visual distinction of brain glioma from normal tissues via targeted photoacoustic and fluorescence navigation. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE[J]. 2020, 27: http://dx.doi.org/10.1016/j.nano.2020.102204.
[33] Hu, Xi, Li, Fangyuan, Xia, Fan, Guo, Xia, Wang, Nan, Liang, Lili, Yang, Bo, Fan, Kelong, Yan, Xiyun, Ling, Daishun. Biodegradation-Mediated Enzymatic Activity-Tunable Molybdenum Oxide Nanourchins for Tumor-Specific Cascade Catalytic Therapy. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2020, 142(3): 1636-1644, http://dx.doi.org/10.1021/jacs.9b13586.
[34] Wang, Zhuoran, Zhang, Ruofei, Yan, Xiyun, Fan, Kelong. Structure and activity of nanozymes: Inspirations for de novo design of nanozymes. MATERIALS TODAYnull. 2020, 41: 81-119, http://dx.doi.org/10.1016/j.mattod.2020.08.020.
[35] Shen, Xinyu, Ma, Ruonan, Huang, Yixin, Chen, Lei, Xu, Zhuobin, Li, Dandan, Meng, Xiangqin, Fan, Kelong, Xi, Juqun, Yan, Xiyun, Koo, Hyun, Yang, Yili, Jiang, Jing, Gao, Lizeng. Nano-decocted ferrous polysulfide coordinates ferroptosis-like death in bacteria for anti-infection therapy. NANO TODAY[J]. 2020, 35: http://dx.doi.org/10.1016/j.nantod.2020.100981.
[36] Meng, Xiangqin, Zare, Iman, Yan, Xiyun, Fan, Kelong. Protein-protected metal nanoclusters: An emerging ultra-small nanozyme. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGYnull. 2020, 12(3): http://dx.doi.org/10.1002/wnan.1602.
[37] Jiang, Bing, Fang, Long, Wu, Kongming, Yan, Xiyun, Fan, Kelong. Ferritins as natural and artificial nanozymes for theranostics. THERANOSTICSnull. 2020, 10(2): 687-706, http://dx.doi.org/10.7150/thno.39827.
[38] 马龙, 范克龙. 纳米酶和铁蛋白新特性的发现和应用. 自然杂志[J]. 2020, 42(1): 1-11, http://lib.cqvip.com/Qikan/Article/Detail?id=7101105425.
[39] Xu, Bolong, Wang, Hui, Wang, Weiwei, Gao, Lizeng, Li, Shanshan, Pan, Xueting, Wang, Hongyu, Yang, Hailong, Meng, Xiangqin, Wu, Qiuwen, Zheng, Lirong, Chen, Shenming, Shi, Xinghua, Fan, Kelong, Yan, Xiyun, Liu, Huiyu. A Single-Atom Nanozyme for Wound Disinfection Applications. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(15): 4911-4916, https://www.webofscience.com/wos/woscc/full-record/WOS:000463739900018.
[40] Jiang, Bing, Zhang, Ruofei, Zhang, Jianlin, Hou, Yaxin, Chen, Xuehui, Zhou, Meng, Tian, Xiuyun, Hao, Chunyi, Fan, Kelong, Yan, Xiyun. GRP78-targeted ferritin nanocaged ultra-high dose of doxorubicin for hepatocellular carcinoma therapy. THERANOSTICS[J]. 2019, 9(8): 2167-2182, https://www.webofscience.com/wos/woscc/full-record/WOS:000464623500004.
[41] Tao Wang, Jiuyang He, Demin Duan, Bing Jiang, Peixia Wang, Kelong Fan, Minmin Liang, Xiyun Yan. Bioengineered magnetoferritin nanozymes for pathological identification of high-risk and ruptured atherosclerotic plaques in humans. 纳米研究:英文版[J]. 2019, 12(4): 863-868, http://lib.cqvip.com/Qikan/Article/Detail?id=7001880742.
[42] Jin, Yiliang, He, Jiuyang, Fan, Kelong, Yan, Xiyun. Ferritin variants: inspirations for rationally designing protein nanocarriers. NANOSCALEnull. 2019, 11(26): 12449-12459, https://www.webofscience.com/wos/woscc/full-record/WOS:000474160000002.
[43] Fan, Kelong, Yan, Xiyun. Nanozyme based tumor catalytic theranostics. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETYnull. 2019, 258: https://www.webofscience.com/wos/woscc/full-record/WOS:000525055501290.
[44] Zhang, Ruofei, Zhou, Yunlong, Yan, Xiyun, Fan, Kelong. Advances in chiral nanozymes: a review. MICROCHIMICA ACTAnull. 2019, 186(12): https://www.webofscience.com/wos/woscc/full-record/WOS:000498188200006.
[45] He, Jiuyang, Fan, Kelong, Yan, Xiyun. Ferritin drug carrier (FDC) for tumor targeting therapy. JOURNAL OF CONTROLLED RELEASEnull. 2019, 311: 288-300, http://dx.doi.org/10.1016/j.jconrel.2019.09.002.
[46] Ding, Hui, Cai, Yanjuan, Gao, Lizeng, Liang, Minmin, Miao, Beiping, Wu, Hanwei, Liu, Yang, Xie, Ni, Tang, Aifa, Fan, Kelong, Yan, Xiyun, Nie, Guohui. Exosome-like Nanozyme Vesicles for H2O2-Responsive Catalytic Photoacoustic Imaging of Xenograft Nasopharyngeal Carcinoma. NANO LETTERS[J]. 2019, 19(1): 203-209, https://www.webofscience.com/wos/woscc/full-record/WOS:000455561300025.
[47] 焦健, 范克龙, 胡志刚, 阎锡蕴, 杜鹏. 纳米酶的发展态势与优先领域分析. 中国科学:化学[J]. 2019, 49(12): 1442-1453, https://www.sciengine.com/doi/10.1360/SSC-2019-0138.
[48] Meng, Xiangqin, Fan, Kelong, Yan, Xiyun. Nanozymes: an emerging field bridging nanotechnology and enzymology. SCIENCE CHINA-LIFE SCIENCES[J]. 2019, 62(11): 1543-1546, http://lib.cqvip.com/Qikan/Article/Detail?id=7100346953.
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科研活动

   
科研项目
( 1 ) 中国科学院创新交叉团队, 主持, 部委级, 2021-01--2023-12
( 2 ) 一种肝细胞肝癌特异性靶分子的鉴定及其靶向纳米药物载体的设计, 主持, 国家级, 2019-01--2020-12
( 3 ) 一种可实现肿瘤超早期成像的多模靶向纳米探针, 主持, 国家级, 2020-01--2022-12
( 4 ) 纳米酶的仿生设计及其生物医学应用, 主持, 国家级, 2022-01--2024-12
( 5 ) 肿瘤微环境的免疫抑制关键机制研究和精准纳米基因治疗, 主持, 国家级, 2021-12--2026-11

指导学生

现指导学生

谢佳颖  硕士研究生  071010-生物化学与分子生物学  

张宝丽  博士研究生  071010-生物化学与分子生物学  

向建全  博士研究生  071010-生物化学与分子生物学  

李建茹  博士研究生  071010-生物化学与分子生物学