基本信息

赵超  女  博导  中国科学院深圳先进技术研究院
电子邮件: chao.zhao@siat.ac.cn
通信地址: 深圳市南山区西丽大学城学苑大道1068号
邮政编码: 518055

招生信息

   
招生专业
070302-分析化学
071010-生物化学与分子生物学
083100-生物医学工程
招生方向
单细胞质谱多组学和成像研究
肿瘤代谢
环境毒理

教育背景

2009-09--2013-06   中科院生态环境研究中心   博士
2006-09--2009-06   大连海事大学   硕士
2002-09--2006-06   沈阳工业大学   学士

工作经历

   
2019-09~现在, 中国科学院深圳先进技术研究院医工所, 副研究员
2014-12~2019-07,香港浸会大学环境与生物分析国家重点实验室, 博士后
2013-09~2014-11,中科院生态环境研究中心环境化学与生态毒理学国家重点实验室, 博士后

奖励

   
(1) 中国分析测试协会科学技术奖 (CAIA奖) (6/10), 特等奖, 国家级, 2020
(2) 深圳市海外高层次人才“孔雀计划”C类, 省级, 2019
(3) 中国科学院深圳先进技术研究“优秀青年创新基金”, 研究所(学校), 2019
(4) Young Scientist Travel Award-Asia Oceania Mass Spectrometry Conference 2017, 其他, 2017
(5) 中国分析测试协会科学技术奖 (CAIA奖) (4/10), 特等奖, 国家级, 2015
(6) 香江学者奖, 专项, 2014
(7) 中国分析测试协会科学技术奖 (CAIA奖) (7/10), 一等奖, 国家级, 2013

发表论文

   
(1) Data Filtering and Its Prioritization in Pipelines for Spatial Segmentation of Mass Spectrometry Imaging, ANALYTICAL CHEMISTRY, 2021, 通讯作者
(2) Breast cancer proliferation and deterioration-associated metabolic heterogeneity changes induced by exposure of bisphenol S, a widespread replacement of bisphenol A, JOURNAL OF HAZARDOUS MATERIALS, 2021, 第 1 作者
(3) 基于质谱成像和组学分析的环境毒理研究, 化学进展, 2021, 第 1 作者
(4) Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy, SCIENCE BULLETIN, 2021, 第 1 作者
(5) Three-dimensional quantitative mass spectrometry imaging in complex system: From subcellular to whole organism, MASS SPECTROMETRY REVIEWS, 2020, 第 1 作者
(6) 孕鼠PM2.5暴露如何影响后代行为变化?, How does gestational PM2.5 exposure affect the offspring behaviors?, 科学通报, 2020, 第 2 作者
(7) Evaluation of the splenic injury following exposure of mice to bisphenol S: A mass spectrometry-based lipidomics and imaging analysis, ENVIRONMENT INTERNATIONAL, 2020, 第 1 作者
(8) Preparation of Frozen Sections of Multicellular Tumor Spheroids Coated with Ice for Mass Spectrometry Imaging, ANALYTICAL CHEMISTRY, 2020, 第 2 作者
(9) Metabolic perturbation, proliferation and reactive oxygen species jointly contribute to cytotoxicity of human breast cancer cell induced by tetrabromo and tetrachloro bisphenol A, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 第 1 作者
(10) Bisphenol S induced epigenetic and transcriptional changes in human breast cancer cell line MCF-7, ENVIRONMENTAL POLLUTION, 2019, 第 2 作者
(11) Immunotoxic Potentials of Bisphenol F Mediated through Lipid Signaling Pathways on Macrophages, Environmental Science & Technology, 2019, 第 1 作者
(12) Omics approach reveals metabolic disorders associated with the cytotoxicity of airborne particulate matter in human lung carcinoma cells, ENVIRONMENTAL POLLUTION, 2019, 第 1 作者
(13) Identification of glycerophospholipid fatty acid remodeling by using mass spectrometry imaging in bisphenol S induced mouse liver, CHINESE CHEMICAL LETTERS, 2018, 第 1 作者
(14) MALDI-MS Imaging Reveals Asymmetric Spatial Distribution of Lipid Metabolites from Bisphenol S-Induced Nephrotoxicity, ANALYTICAL CHEMISTRY, 2018, 第 1 作者
(15) Liquid chromatography-mass spectrometry-based metabolomics and lipidomics reveal toxicological mechanisms of bisphenol F in breast cancer xenografts, JOURNAL OF HAZARDOUS MATERIALS, 2018, 第 1 作者
(16) Bisphenol S exposure modulate macrophage phenotype as defined by cytokines profiling, global metabolomics and lipidomics analysis, SCIENCE OF THE TOTAL ENVIRONMENT, 2017, 第 1 作者
(17) Boronic acid-mediated polymerase chain reaction for gene- and fragment-specific detection of 5-hydroxymethylcytosine, NUCLEIC ACIDS RESEARCH, 2014, 第 1 作者
(18) Capillary Monolithic Bioreactor of Immobilizing Snake Venom Phosphodiesterase for Mass Spectrometry Based Oligodeoxynucleotide Sequencing, Analytical Chemistry, 2012, 第 1 作者
发表著作
(1) Air Pollution, Climate, and Health: An Integrated Perspective on Their Interactions, Chapter 9: Airborne particulate matter and its organic components: Complex triggers of human disease, Elsevier, 2021-05, 第 1 作者

科研活动

   
项目
( 1 ) 实时在线微流控芯片质谱技术用于乳腺肿瘤代谢分型的研究, 负责人, 研究所自主部署, 2020-01--2022-01
( 2 ) 双酚A类似物在人乳腺癌裸鼠模型中的代谢活化途径和毒理效应研究, 负责人, 国家任务, 2016-01--2018-12
( 3 ) 太原和广州市大气细颗粒物诱导呼吸系统疾病的质谱代谢组学研究, 参与, 国家任务, 2016-01--2019-12
( 4 ) 毛细管电泳-双光子荧光偏振单分子检测装置, 参与, 国家任务, 2014-01--2017-12
( 5 ) 基于多重分子相互作用的纳米材料生物效应的研究, 参与, 国家任务, 2011-01--2013-12
( 6 ) 基于 3D 细胞微球的质谱组学和成像新方法及其在 酚类污染物毒性评价中的应用, 负责人, 地方任务, 2021-01--2023-12
( 7 ) PM2.5跨代际暴露诱导神经退行性疾病作用机制研究, 负责人, 地方任务, 2021-01--2023-12
( 8 ) 基于多维度便携式微芯片分析传感系 统的环境污染物检测技术研发及应用示范, 参与, 地方任务, 2020-01--2022-12
( 9 ) 低剂量双酚A替代物影响乳腺癌肿瘤形成及其诱导脏器损伤的机制研究, 负责人, 国家任务, 2022-01--2025-12
口头报告
(1)Multiple Imaging Mass Spectrometry Analysis Reveals the Evolution of Tumor Metabolic Heterogeneity    中国质谱学术大会   2018-11-24
(2)Ceramide Accumulation and Altered RNA Splicing Contributing to Cytotoxicity of Human Lung Epithelial Cells Induced by Airborne Particulate Matter: Integrative Analysis of Metabolomics, Lipidomics and Proteomics   The international conference on environmental pollution and Health   2018-05-19
(3)MALDI-TOF MS Imaging for Environmental Toxicology   Clinical & Pharmaceutical Solutions through Analysis (CPSA)   2018-04-18
(4)Multi-omics and Spatial Imaging Analysis Reveal Toxicological Mechanisms of Bisphenol F in Breast Cancer Xenografts   7th Asia Oceania Mass Spectrometry Conference 2017   2017-12-12
(5)Reactive Oxygen Species and Nucleotide Metabolism Jointly Contribute to HepG2 Cytotoxicity Induced by Tetrabromobisphenol A   15th International Conference on Environmental Science and Technology   2017-09-01
(6)Liquid Chromatography-Mass Spectrometry-based Metabolomics and Lipidomics Reveal Toxicological Mechanisms of Bisphenol F in Breast Cancer Xenografts   HKSMS Symposium 2017 & 19th Annual General Meeting   2017-06-24

合作情况

西安交通大学第二附属医院

复旦大学肿瘤医院