基本信息

荆莉红  博士 研究生导师  中国科学院化学研究所
电子邮件: jinglh@iccas.ac.cn
通信地址: 北京市海淀区中关村北一街2号
邮政编码: 100190

研究领域

半导体纳米晶及其复合材料的液相合成、光学及磁学性质研究
近红外I-II区发光纳米探针的构建研究
磁性/光学多模态分子影像探针的构建研究
重大疾病如肿瘤活体影像诊断
重大疾病如肿瘤恶性生物学事件的无创、实时监测及预后评估
重大传染病相关医疗大数据管理及活体高通量生物信息分析

招生信息

化学,材料学,纳米科学与技术,生物医学工程,化学生物学,分子生物学,肿瘤学,免疫学、影像学等

招生专业
070304-物理化学
招生方向
半导体纳米晶体的设计合成及光学性能调控机制
肿瘤活体影像诊断及高通量生物信息分析

教育背景

2011-01--2011-03   香港城市大学   Research Assistant
2005-09--2011-07   中国科学院化学研究所   硕博连读/博士学位
2001-09--2005-07   河南大学   学士学位

工作经历

   
工作简历
2017-01~2018-02,美国麻省理工学院 (MIT), 访问学者
2016-09~2016-10,香港城市大学 (CityU), Research Fellow
2015-04~现在, 中国科学院化学研究所 (ICCAS), 副研究员
2013-02~2013-05,香港城市大学, Research Associate
2011-07~2015-03,中国科学院化学研究所, 助理研究员

专利与奖励

奖励信息
(1) 中国科学院化学研究所青年科学奖特别优秀奖, 特等奖, 研究所(学校), 2020
(2) 中国科学院化学研究所青年科学奖特别优秀奖, 特等奖, 研究所(学校), 2016
(3) 中国科学院化学研究所青年科学奖特别优秀奖, 特等奖, 研究所(学校), 2015
专利成果
( 1 ) 一种半导体纳米晶的表面生物相容性修饰方法, 发明, 2021, 第 1 作者, 专利号: 202110110770.1
( 2 ) 一种近红外发光的磁性量子点及其制备方法与应用, 发明, 2021, 第 1 作者, 专利号: 202110109924.5
( 3 ) 一种温度敏感的准硫化亚铜发光二维半导体的制备方法, 发明, 2020, 第 3 作者, 专利号: 202011221740X
( 4 ) 一种醇类辅助制备长余辉纳米晶体的方法, 发明, 2020, 第 3 作者, 专利号: 2020112224210

出版信息

   
发表论文
(1) Two-Dimensional and Subnanometer-Thin Quasi-Copper-Sulfide Semiconductor Formed upon Copper-Copper Bonding, ACS Nano, 2021, 通讯作者
(2) A Cyclodextrin-hosted Ir(III) Complex for Ratiometric Mapping of Tumor Hypoxia in vivo, Adv. Sci., 2021, 第 5 作者
(3) Turning-on Persistent Luminescence out of Zinc Aluminate Nanoparticles by Instilling Antisite Defect under Mild Conditions, Nanoscale, 2021, 通讯作者
(4) Continuous Flow Synthesis of Persistent Luminescent Chromium-Doped Zinc Gallate Nanoparticles, J. Phys. Chem. Lett., 2021, 通讯作者
(5) Longer and Stronger: Improving Persistent Luminescence in Size-Tuned Zinc Gallate Nanoparticles by Alcohol-Mediated Chromium Doping, ACS Nano, 2020, 通讯作者
(6) Doping Lanthanide Nanocrystals with Non-lanthanide ions to Simultaneously Enhance Up- and Down-conversion Luminescence, Front. Chem., 2020, 通讯作者
(7) Enabling Nanopore for Sensing Individual Amino Acids by a Derivatization Strategy, J. Mater. Chem. B, 2020, 通讯作者
(8) Nanoparticles Weaponized with Built-in Functions for Imaging-Guided Cancer Therapy, View, 2020, 第 1 作者
(9) Manganese-Mediated Growth of ZnS Shell on KMnF3:Yb,Er Cores towards Enhanced Up/Downconversion Luminescence, ACS Appl. Mater. Interfaces, 2020, 通讯作者
(10) Bio-inspired Cryoprotectants of Glucose-based Carbon Dots, ACS Appl. Bio Mater., 2020, 第 5 作者
(11) Biocompatible Near-infrared Quantum Dots Delivered to the Skin by Microneedle Patches Record Vaccination, Sci. Transl. Med., 2019, 第 1 作者
(12) Biocompatible Off-stoichiometric Copper Indium Sulfide Quantum Dots with Tunable Near-Infrared Emission via Aqueous Based Synthesis, Chem. Commun., 2019, 通讯作者
(13) Upconversion Luminescence Mediated Photodynamic Therapy through Hydrophilically Engineered Porphyrin, Chem. Eng. Process., 2019, 通讯作者
(14) Emitting/Sensitizing Ions Spatially Separated Lanthanide Nanocrystals for Visualizing Tumors Simultaneously through Up- and Down-conversion Near-infrared II Luminescence in Vivo, Small, 2019, 第 6 作者
(15) Thermally Activated Upconversion Near-Infrared Photoluminescence from Carbon Dots Synthesized via Microwave Assisted Exfoliation, Small, 2019, 其他(合作组作者)
(16) Narrowing the Photoluminescence of Aqueous CdTe Quantum Dots via Ostwald Ripening Suppression Realized by Programmed Dropwise Precursor Addition, J. Phys. Chem. C, 2018, 通讯作者
(17) Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents, Adv. Mater., 2018, 第 2 作者
(18) Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in vivo, J. Am. Chem. Soc., 2018, 第 6 作者
(19) Molecular Mechanisms for Delicately Tuning the Morphology and Property of Fe3O4 Nanoparticle Clusters, CrystEngComm, 2018, 第 2 作者
(20) Materials Aspects of Semiconductor Nanocrystals for Optoelectronic Applications, Mater. Horiz., 2017, 第 1 作者
(21) Growth Mechanism of Strongly Emitting CH3NH3PbBr3 Perovskite Nanocrystals with a Tunable Bandgap, Nat. Commun., 2017, 第 6 作者
(22) The Yin and Yang of Coordinating Co-Solvents in the Size-Tuning of Fe3O4 Nanocrystals through Flow Synthesis, Nanoscale, 2017, 第 2 作者
(23) Aqueous Based Semiconductor Nanocrystals, Chem. Rev., 2016, 第 1 作者
(24) Differently Sized Magnetic/Upconversion Luminescent NaGdF4:Yb,Er Nanocrystals: Flow Synthesis and Solvent Effects, Chem. Commun., 2016, 第 2 作者
(25) Detection of Early Primary Colorectal Cancer with Upconversion Luminescence NPs‐Based Molecular Probes, Nanoscale, 2016, 第 8 作者
(26) Insight into Strain Effects on Band Alignment Shifts, Carrier Localization and Recombination Kinetics in CdTe/CdS Core/Shell Quantum Dots, J. Am. Chem. Soc., 2015, 第 1 作者
(27) Chemical Spacer Design for Engineering the Relaxometric Properties of Core-Shell Structured Rare Earth Nanoparticles, Chem. Mater., 2015, 第 4 作者
(28) Flow Synthesis of Biocompatible Fe3O4 Nanoparticles: Insight into the Effects of Residence Time, Fluid Velocity, and Tube Reactor Dimension on Particle Size Distribution, Chem. Mater., 2015, 第 3 作者
(29) Super-stable Centimetre-scale Inverse Opal Belts Integrated with CdTe QDs for Narrow Band Fluorescence Optical Waveguiding, J. Mater. Chem. C, 2015, 第 7 作者
(30) Aqueous Synthesis of PEGylated Copper Sulfide Nanoparticles for Photoacoustic Imaging of Tumors, Nanoscale, 2015, 第 3 作者
(31) Magnetically Engineered Semiconductor Quantum Dots as Multimodal Imaging Probes, Adv. Mater., 2014, 第 1 作者
(32) Magnetically Engineered Cd-Free Quantum Dots as Dual-modality Probes for Fluorescence/Magnetic Resonance Imaging of Tumors, Biomaterials, 2014, 通讯作者
(33) Detection of Epstein-Barr Virus Infection In Cancer by Using Highly Specific Nanoprobe Based on dBSA Capped CdTe Quantum Dots, RSC Adv., 2014, 第 2 作者
(34) Revisiting the Coordination Chemistry for Preparing Manganese Oxide Nanocrystals in the Presence of Oleylamine and Oleic Acid, Nanoscale, 2014, 第 2 作者
(35) Anchoring Group Effects of Surface Ligand on Magnetic Properties of Fe3O4 Nanoparticles: Towards High Performance MRI Contrast Agents, Adv. Mater., 2014, 第 2 作者
(36) In Situ 111In-doping for Achieving Biocompatible and Non-leachable 111In-labeled Fe3O4 Nanoparticles, Chem. Commun., 2014, 第 5 作者
(37) Aqueous Manganese-Doped Core/Shell CdTe/ZnS Quantum Dots with Strong Fluorescence and High Relaxivity, J Phys. Chem. C, 2013, 第 1 作者
(38) Bifunctional Superparticles Achieved by Assembling Fluorescent CuInS2@ZnS Quantum Dots and Amphibious Fe3O4 Nanocrystals, J. Phys. Chem. C, 2013, 第 6 作者
(39) Surface-biofunctionalized Multicore/Shell CdTe@SiO2 Composite Particles for Immunofluorescence Assay, Nanotechnology, 2011, 第 1 作者
(40) Aqueous Synthesis of CdTe Nanocrystals: Progresses and Perspectives, Chem. Comm., 2011, 第 2 作者
(41) Quantum Dot-Antisense Oligonucleotide Conjugates for Multifunctional Gene Transfection, mRNA Regulation, and Tracking of Biological Processes, Biomaterials, 2011, 第 3 作者
(42) Gelification: An Effective Measure for Achieving Differently Sized Biocompatible Fe3O4 Nanocrystals through a Single Preparation Recipe, J. Am. Chem. Soc., 2011, 第 4 作者
(43) Lateral Flow Immunochromatographic Assay for Sensitive Pesticide Detection by Using Fe3O4 Nanoparticle Aggregates as Color Reagents, Anal. Chem., 2011, 第 6 作者
(44) Highly Fluorescent CdTe@SiO2 Particles Prepared via Reverse Microemulsion Method, Chem. Mater., 2010, 第 1 作者
(45) Decorating multi-walled carbon nanotubes with quantum dots for construction of multi-color fluorescent nanoprobes, Nanotechnology, 2010, 第 6 作者
(46) Schneider, Potential of Ultra Small Particles for Drug Delivery across Human Skin, J. Biomed. Nanotechnol., 2010, 第 3 作者
(47) Coating Aqueous Quantum Dots with Silica via Reverse Microemulsion Method: Towards Size-controllable and Robust Fluorescent Nanoarticles, Chem. Mater., 2007, 第 2 作者

科研活动

   
科研项目
( 1 ) 肿瘤相关巨噬细胞活体成像及胃癌预后研究, 主持, 国家级, 2017-01--2020-12
( 2 ) 基于过渡金属掺杂无镉量子点双模态分子影像探针的构建及性质研究, 主持, 国家级, 2013-01--2015-12
( 3 ) 基于纳米探针的疫苗在体释放动力学研究, 参与, 部委级, 2019-01--2021-12
( 4 ) 新型纳米氧化铁磁共振造影剂的宏量制备及临床转化研究, 参与, 国家级, 2018-05--2023-04
( 5 ) 面向肿瘤相关巨噬细胞在体动态可视化监测的多模态分子影像探针的构建研究, 主持, 市地级, 2019-01--2020-12
( 6 ) 基于双模态纳米探针的肿瘤相关巨噬细胞活体成像及其潜在胃癌预后监测应用研究, 主持, 市地级, 2015-08--2016-07