基本信息

常钰磊  男  研究员 博士生导师

发光学及应用国家重点实验室

中国科学院长春光学精密机械与物理研究所
电子邮件: yuleichang@ciomp.ac.cn
通信地址: 东南湖大路3888号
邮政编码: 130033

主页:

研究领域

在凝聚态物质中的元激发,凝聚态中的发光动力学过程研究以及光电子材料与器件、生物体系中的光与生物分子的相互作用、荧光共振能量传递等研究领域具有坚实的理论基础和丰富的工作经验。在稀土发光材料与物理、生物光子学等研究方向具有研究特色和优势。


招生信息

热烈欢迎具有物理、材料、化学,光学工程等学科背景的同学报考硕士、博士研究生,鼓励学科交叉。热诚期待相关方向的博士毕业生开展博士后合作研究!

优先考虑背景包括:

•稀土(镧系)掺杂发光材料和物理

•生物光子学:NIR-II荧光成像/光疗/生物传感检测

•纳米颗粒的表面修饰:相转移/抗体偶联等

•发光的动态调控:铁电/磁光调制等

•发光动力学过程模拟:蒙特卡罗或其他方法


招生专业
070205-凝聚态物理
招生方向
无机光功能材料
稀土发光材料与物理

教育背景

2008-09--2013-06   吉林大学   博士
2004-09--2008-06   吉林大学   学士

工作经历

   

专利与奖励

1

一种Bi基纳米复合材料及其制备方法和应用

ZL 2021 1 1091782.0

2022-10-04


2

一种内外兼修的复合纳米光敏剂及其制备方法和应用

ZL 2019 10020528.8

2021-06-29


3

一种复合物及其应用

ZL 2016 1 1239573.5

2020-07-24


4

一种凝血酶的检测方法

ZL 2016 1 1178768.3

2019-10-25


5

一种核酸检测的复合物及其制备方法与核酸检测的方法

CN 106636405 B

2021-01-05



奖励信息
(1) 光子上转换纳米材料、物理及其生物医学应用研究, 二等奖, 省级, 2021
(2) 新型多功能复合纳米药物载体的合成及在肺癌早期诊断治疗上研究, 二等奖, 省级, 2013

出版信息

   
发表论文
(1) Amplifying oxidative stress utilizing multiband luminescence of lanthanide nanoparticles for eliciting systemic antitumor immunity, Chemical Engineering Journal, 2023, 通讯作者
(2) ​Super-enhancement Photon Upconversion Nanoparticles for Photo-activated Nanocryometer, Nano Letters, 2023, 通讯作者
(3) Bright Tm(3+)-based downshifting luminescence nanoprobe operating around 1800 nm for NIR-IIb and c bioimaging, Nature Communications, 2023, 通讯作者
(4) Ultra-Sensitive water detection based on NaErF4@NaYF4 high-level-doping upconversion nanoparticles, Applied Surface Science, 2022, 通讯作者
(5) Manipulating the injected energy flux via host-sensitized nanostructure for improving multiphoton upconversion luminescence of Tm3+, Nano Letters, 2022, 通讯作者
(6) Modulation of the Tumor Immune Microenvironment by Bi2 Te3 -Au/Pd-Based Theranostic Nanocatalysts Enables Efficient Cancer Therapy, Adv Healthc Mater, 2022, 通讯作者
(7) AIE-active Ir(III) complexes functionalised with a cationic Schiff base ligand: synthesis, photophysical properties and applications in photodynamic therapy, Dalton Transactions, 2022, 通讯作者
(8) An active-passive strategy for enhanced synergistic photothermal-ferroptosis therapy in the NIR-I/II biowindows†, Biomaterials Science, 2022, 通讯作者
(9) AIE-active iridium(III) complex integrated with upconversion nanoparticles for NIR-irradiated photodynamic therapy, CHEMICAL COMMUNICATIONS, 2022, 通讯作者
(10) Hybrid Nanoplatform: Enabling a Precise Antitumor Strategy via Dual-Modal Imaging-Guided Photodynamic/Chemo-/Immunosynergistic Therapy, ACS NANO, 2021, 通讯作者
(11) Mitochondria-Immobilized Unimolecular Fluorescent Probe for Multiplexing Imaging of Living Cancer Cells, ANALYTICAL CHEMISTRY, 2020, 通讯作者
(12) Polyphotosensitizer nanogels for GSH-responsive histone deacetylase inhibitors delivery and enhanced cancer photodynamic therapy, COLLOIDS AND SURFACES B-BIOINTERFACES, 2020, 通讯作者
(13) Optical imaging and pH-awakening therapy of deep tissue cancer based on specific upconversion nanophotosensitizers, BIOMATERIALS, 2020, 通讯作者
(14) Assembly of upconversion nanophotosensitizer in vivo to achieve scatheless real-time imaging and selective photodynamic therapy, BIOMATERIALS, 2019, 通讯作者
(15) Near- infrared light- mediated and nitric oxide- supplied nanospheres for enhanced synergistic thermo- chemotherapy, JOURNAL OF MATERIALS CHEMISTRY B, 2019, 通讯作者
(16) Near-infrared light-mediated and nitric oxide-supplied nanospheres for enhanced synergistic thermo-chemotherapy, Journal of Materials Chemistry B, 2019, 通讯作者
(17) Near Infrared Light Sensitive Ultraviolet-Blue Nanophotoswitch for Imaging-Guided "Off-On" Therapy, ACS NANO, 2018, 通讯作者
(18) An 800 nm driven NaErF4@NaLuF4 upconversion platform for multimodality imaging and photodynamic therapy, NANOSCALE, 2018, 通讯作者
(19) Precise Photodynamic Therapy of Cancer via Subcellular Dynamic Tracing of Dual-loaded Upconversion Nanophotosensitizers, SCIENTIFIC REPORTS, 2017, 第 1 作者
(20) Bcl-2 inhibitor uploaded upconversion nanophotosensitizers to overcome the photodynamic therapy resistance of cancer through adjuvant intervention strategy, BIOMATERIALS, 2017, 通讯作者
(21) Amphiphilic copolymer and TPGS mixed magnetic hybrid micelles for stepwise targeted co-delivery of DOX/TPP-DOX and image-guided chemotherapy with enhanced antitumor activity in liver cancer, RSC ADVANCES, 2017, 通讯作者
(22) Investigation on Ligand Exchange Kinetics on CdSe/ZnS Quantum Dot Surface Utilizing Pyrene as Flourescent Probe, CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 第 1 作者
(23) A highly effective in vivo photothermal nanoplatform with dual imaging-guided therapy of cancer based on the charge reversal complex of dye and iron oxide, JOURNAL OF MATERIALS CHEMISTRY B, 2015, 第 1 作者
(24) Dendrimer functionalized water soluble magnetic iron oxide conjugates as dual imaging probe for tumor targeting and drug delivery, POLYMER CHEMISTRY, 2013, 第 1 作者
(25) Synthesis and characterization of DOX-conjugated dendrimer-modified magnetic iron oxide conjugates for magnetic resonance imaging, targeting, and drug delivery, JOURNAL OF MATERIALS CHEMISTRY, 2012, 第 1 作者
(26) Novel water-soluble and pH-responsive anticancer drug nanocarriers: Doxorubicin–PAMAM dendrimer conjugates attached to superparamagnetic iron oxide nanoparticles (IONPs), JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2011, 第 1 作者

科研活动

   
参与会议
(1)Tm3+基纳米发光材料设计及其NIR-II生物成像应用   第九届全国掺杂纳米材料发光性质学术会议   2023-05-19
(2)Tm3+ -based luminescence nanoprobe for NIR-II bioimaging   第十六届生物医学光子学与成像技术国际学术研讨会   2023-03-29
(3)稀土光功能纳米材料的生物应用研究   中国稀土学会2021学术年会   2021-10-22
(4)铒基光功能纳米材料的生物应用探索   2021中国光学学会学术大会   2021-08-30
(5)高浓度稀土活性离子基纳米发光材料设计及其生物成像应用   第八届全国掺杂纳米材料发光性质学术会议   2021-07-22
(6)稀土纳米晶的尺寸、形貌结构可控合成及发光性质研究    中国化学会第32届学术年会,第六分会:无机固态化学   常钰磊*1,王旺,解小雨,杨建龙,陈浩然,涂浪平,孔祥贵   2021-04-19
(7)稀土发光纳米晶生物诊疗现状与趋势分析   稀土晶体专业委员会青年工作委员会第一次会议   2019-12-27
(8)Rare Earth Doped Nanoparticles for Tumor Theranostics   2019-11-16
(9)上转换纳米生物平台的构建及肿瘤诊治中的应用   第一届全国稀土晶体材料与应用研讨会暨稀土化学国际论坛   2019-10-23