1. Genome editing in resource plants 

2. Molecular mechanisms of heavy metal stress in plants

3. Phytoremediation of heavy metal pollution

1992-1996 Undergraduate student, Department of Tea Science, Hunan Agricultural University, Changsha, China

1996-1999, Graduate student, Department of Plant Physiology and Biochemistry, China Agricultural University, Beijing, China

1999-2003, Ph. D. student, Institute of Botany, Chinese Academy of Sciences, Beijing, China

   

2003-2011, Research Assistant, Assistant Professor, Institute of Botany, Chinese Academy of Sciences, Beijing, China

2012-Now, Associate Professor, Institute of Botany, Chinese Academy of Sciences, Beijing, China

2013-2014, Visiting Scholar, Herbert Wertheim College of Medicine, Florida International University, Florida, U.S.A

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Selected publications

1. Haixia Zhao, Liangsheng Wang, Fang-Jie Zhao, Longhua Wu, Anna Liu, Wenzhong Xu*. SpHMA1 is a chloroplast cadmium exporter protecting photochemical reactions in the Cd hyperaccumulator Sedum plumbizincicola. Plant, Cell & Environment, 2019, 42:1112-1124.
2. Dandan Yin, Shanshan Li, Qingyan Shu, Zhaoyu Gu, Qian Wu, Chengyong Feng, Wenzhong Xu*, Liangsheng Wang*. Identification of microRNAs and long non-coding RNAs involved in fatty acid biosynthesis in tree peony seeds. Gene, 2018, 5; 666:72-82.
3. Dandan Yin, Wenzhong Xu, Qingyan Shu, Shanshan Li*, Qian Wu, Chengyong Feng, Zhaoyu Gu, Liangsheng Wang*. Fatty acid desaturase 3 (PsFAD3) from Paeonia suffruticosa reveals high α-linolenic acid accumulation. Plant Science, 2018, 274: 212-222.
4. 尹丹丹、李珊珊、吴倩、冯成庸、李冰、王倩玉、王亮生*、徐文忠*. 我国6种主要木本油料作物的研究进展. 植物学报，2018, 53(1): 110-125.
5. Qian Wu, Pengcheng Li, Huijin Zhang, Chengyong Feng, Shanshan Li*, Dandan Yin, Jie Tian, Wenzhong Xu, Liangsheng Wang*. Relationship between the flavonoid composition and flower colour variation in Victoria. Plant Biol (Stuttg), 2018, 20(4): 674-681.
6. Huan Liu, Haixia Zhao, Longhua Wu, Anna Liu, Fang-Jie Zhao, Wenzhong Xu*. Heavy metal ATPase 3 (HMA3) confers cadmium hypertolerance on the cadmium/zinc hyperaccumulator Sedum plumbizincicola. New Phytologist, 2017, 215(2): 687-698.
7. Huan Liu, Haixia Zhao, Longhua Wu*, Wenzhong Xu*. A genetic transformation method for cadmium hyperaccumulator Sedum plumbizincicola and non-hyperaccumulating ecotype of Sedum alfredii. Frontiers in Plant Science, 2017, 8:1047.
8. Bo Wang^†, Hong Du^†, Zhennan Zhang, Wenzhong Xu*, Xin Deng*. BhbZIP60 from Resurrection plant Boea hygrometrica is an mRNA splicing-activated endoplasmic reticulum stress regulator involved in drought tolerance. Frontiers in Plant Science, 2017, 8:245.
9. Dongmei Li, Zhenpeng Guo*, Cuimei Liu, Jincheng Li, Wenzhong Xu, Yi Chen*. Quantification of near-attomole gibberellins in floral organs dissected from a single Arabidopsis thaliana flower. Plant Journal, 2017, 91(3):547-557.
10. Hongmei Xi, Hua Xu, Wenxiu Xu, Zhenyan He, Wenzhong Xu*, Mi Ma*. A SAL1 loss-of-function Arabidopsis mutant exhibits enhanced cadmium tolerance in association with alleviation of endoplasmic reticulum stress. Plant & Cell Physiology, 2016, 57(6): 1210–1219.
11. Yangyang Sun^†, Wenzhong Xu^†(co-first author), Li Wu, Ruozhong Wang, Zhenyan He, Mi Ma*. An Arabidopsis mutant of inositol pentakisphosphate 2-kinase AtIPK1 displays reduced arsenate tolerance. Plant, Cell & Environment, 2016, 39: 416-426.
12. Zhuoya Zhao^†, Zenan Xing^†, Min Zhou, Yi Chen, Chenzhong Li, Ruozhong Wang, Wenzhong Xu*, Mi Ma. Functional analysis of synthetic DELLA domain peptides and bioactive gibberellin assay using surface plasmon resonance technology. Talanta, 2015, 144: 502–509.
13. Hui Dong, Wenzhong Xu, Jitesh K. Pillai, Charles Packianathan, Barry P. Rosen*. High-throughput screening-compatible assays of As(III) S-adenosylmethionine methyltransferase activity. Analytical Biochemistry, 2015, 480:67-73.
14. Wenzhong Xu^†, Wentao Dai^†, Huili Yan, Sheng Li, Hongling Shen, Yanshan Chen, Hua Xu, Yangyang Sun, Zhenyan He, Mi Ma*. Arabidopsis NIP3;1 plays an important role in arsenic uptake and root-to-shoot translocation under arsenite stress conditions. Molecular Plant, 2015, 8(5):722-33.
15. Zhuoya Zhao, Yanshan Chen, Wenzhong Xu*, Mi Ma. Surface plasmon resonance detection of transgenic Cry1Ac cotton (Gossypium spp.). Journal of Agricultural and Food Chemistry, 2013, 61(12):2964-2969.
16. Yanshan Chen^†, Wenzhong Xu^† (co-first author), Hongling Shen, Huili Yan, Wenxiu Xu, Zhenyan He, Mi Ma*. Engineering arsenic tolerance and hyperaccumulation in plants for phytoremediation by a PvACR3 transgenic approach. Environmental Science & Technology,2013, 47 (16): 9355–9362
17. Hua Xu^†, Wenzhong Xu^†(co-first author), Hongmei Xi, Wenwen Ma, Zhenyan He, Mi Ma*. The ER luminal binding protein (BiP) alleviates Cd^2%2b-induced programmed cell death through endoplasmic reticulum stress–cell death signaling pathway in tobacco cells. Journal of Plant Physiology, 2013, 170 (16): 1434–1441.
18. 吴俐、王若仲、徐文忠*. 拟南芥中myo-肌醇-多磷酸合成与代谢及其信号. 植物学报, 2013. 48 (1): 94–106.
19. Jiangbo Guo, Wenzhong Xu, Mi Ma*. The assembly of metals chelation by thiols and vacuolar compartmentalization conferred increased tolerance to and accumulation of cadmium and arsenic in transgenic Arabidopsis thaliana. Journal of Hazardous Materials, 2012. 199-200: 309-313.
20. 刘安娜、腾瑶、徐文忠*、麻密. 一个编码含VQ 模序蛋白的基因AtARVQ1参与拟南芥对砷酸盐的响应调控. 科学通报,2011.56(23):1891-1898.
21. Yao Teng, Wenzhong Xu*, Mi Ma. cGMP is required for seed germination in Arabidopsis thaliana. Journal of Plant Physiology, 2010, 167(11):885-9.
22. Beibei Li^†, Wenzhong Xu^†(co-first author), Yunyuan Xu, Yuanyuan Zhang, Tai Wang, Yue Bai, Chenggui Han, Aimin Zhang, Zhihong Xu and Kang Chong*. Integrative study on proteomics, molecular physiology, and genetics reveals an accumulation of cyclophilin-like protein, TaCYP20-2, leading to an increase of Rht protein and dwarf in a novel GA-insensitive mutant (gaid) in Wheat. Journal of Proteome Research, 2010, 9(8):4242-53.
23. Wenwen Ma^†, Wenzhong Xu^†(co-first author), Hua Xu, Yanshan Chen, Zhenyan He, Mi Ma*. Nitric oxide modulates cadmium influx during cadmium-induced programmed cell death in tobacco BY-2 cells. Planta, 2010, 232(2):325-35.
24. Xuexi Yang, Hui Chen, Xiaojing Dai, Wenzhong Xu, Zhenyan He and Mi Ma*. Evidence of vacuolar compartmentalization of arsenic in the hyperaccumulator Pteris vittata. Chinese Science Bulletin 2009, 54(22): 4229-4233.
25. Jiangbo Guo, Xiaojing Dai, Wenzhong Xu, Mi Ma*. Overexpressing GSH1 and AsPCS1 simultaneously increases the tolerance and accumulation of cadmium and arsenic in Arabidopsis thaliana. Chemosphere 2008, 72: 1020-1026.
26. Yongqiang Zheng, Xiaojing Dai, Lei Wang, Wenzhong Xu, Zhenyan He, Mi Ma*. Arsenate reduces copper phytotoxicity in gametophytes of Pteris vittata. Journal of Plant Physiology 2008, 165: 1906-1916.
27. Yongqiang Zheng, Wenzhong Xu, Zhenyan He, Mi Ma*.  Plant regeneration of the arsenic hyperaccumulator Pteris vittata L. from spores and identification of its tolerance and accumulation of arsenic and copper. Acta Physiologiae Plantarum 2008, 30: 249-255.
28. Xuexi Yang, Hui Chen, Wenzhong Xu, Zhenyan He, Mi Ma*.  Hyperaccumulation of arsenic by callus, sporophytes and gametophytes of Pteris vittata cultured in vitro. Plant Cell Reports 2007, 26: 1889-1897
29. Jiangchuan Li, Jiangbo Guo, Wenzhong Xu, Mi Ma*. RNAi-mediated silencing of phytochelatin synthase gene reduce cadmium accumulation in rice seeds. Journal of Integrative Plant Biology 2007, 49: 1032-1037.
30. Haiyan Zhang, Wenzhong Xu, Wentao Dai, Zhenyan He, Mi Ma*. Functional characterization of cadmium-responsive garlic gene AsMT2b: a new member of metallothionein family. Chinese Science Bulletin 2006, 51: 409-416.
31. Jiangchuan Li, Jiangbo Guo, Wenzhong Xu, Haiyan Zhang, Mi Ma*. Enhanced cadmium accumulation in transgenic tobacco expressing the phytochelatin synthase gene of Cynodon dactylon. Journal of Integrative Plant Biology 2006, 48: 928-937.
32. 詹宝、徐文忠、麻密*. 砷超富集植物蜈蚣草原生质体的分离及其抗砷性分析. 植物学通报 2006, 23(4): 363-367.
33. Haiyan Zhang, Wenzhong Xu, Jiangbo Guo, Zhenyan He, Mi Ma*. Coordinated responses of phytochelatins and metallothioneins to heavy metals in garlic seedlings. Plant Science 2005, 169: 1059-1065.
34. 徐文忠、雍伟东、徐云远、梁铁兵、白薇、种康*、谭克辉、许智宏、朱至清. 利用反义基因技术分析春化相关基因VER17在小麦花发育和开花中的功能. 植物生理与分子生物学学报 2005, 31: 71-77.
35. 孙振元*，徐文忠，赵梁军，刘淑兰. 高pH值和铁素对毛白杜鹃和迎红杜鹃根系Fe^3%2b还原酶活性的影响. 核农学报2005, 19(6): 456-460.
36. Wenzhong Xu, Xin Wang, Qi Feng, Lei Zhang, Yaoguang Liu, Bin Han, Kang Chong*, Zhihong Xu, Kehui Tan. The VER2 promoter contains repeated sequences and requires vernalization for its activity in winter wheat (Triticum aestivum L.). Chinese Science Bulletin 2004, 49: 355-362.
37. Xin Wang, Wenzhong Xu, Yunyuan Xu, Kang Chong*, Zhihong Xu, Guixian Xia. Wheat RAN1, a nuclear small G protein, is involved in regulation of cell division in yeast. Plant Science 2004, 167: 1183-1190.
38. Weidong Yong, Yunyuan Xu, Wenzhong Xu, Ning Li, Jinsong Wu, Tiebing Liang, Kang Chong*, Zhihong Xu, Kehui Tan. Functional analysis of the VER2 gene, related to vernalization during floral development in winter wheat. Planta 2003, 217: 261-270.
39. 孙振元*、徐文忠、刘淑兰、赵梁军. 毛白杜鹃耐碱突变体的离体筛选与鉴定. 中南林学院学报 2003, 23(5):53-55.
40. Shiqian Jia, Weidong Yong, Wenzhong Xu, Yunyuan Xu, Jingsong Wu, Kang Chong*, Kehui Tan, Zhihong Xu. Existence of homologous sequences corresponding to cDNA of the ver gene in diverse higher plant species. Cell Research 2001, 11(4):265-271.