General
Wang Wei  Female  master's supervisor  Institute of Virology, CAS
email: wangwei@wh.iov.cn
address: Room 104, Institute of Virology, CAS, Xiaohongshan 44
zip code: 430071


Research Areas

We are interested in the molecular mechanism of the JEV and LASV envelope protein mediated virus-cell membrane fusion. Based on this, we are exploring the entry inhibitors.

Education

Wuhan University School of Medicine, China
Medical student
Sept. 1996-July. 2001

Bachelor of medicine, 2001


Wuhan University School of Medicine, China
Graduate student
Sept. 2001-July. 2005

Master of pathogeny biology, 2005


Huazhong University of Science and Technology, China
Graduate student
Sept. 2005-May. 2009
Doctor of biomedical engineering, 2009


Experience

Sept. 2011-present Research Associate in Virology,

Wuhan Institute of Virology, Chinese Academy of Sciences,


Sept. 2009-Aug. 2011 Postdoctoral Research Fellow
Wuhan Institute of Virology, Chinese Academy of Sciences,


Publications

   
Papers
(1) The ubiquitin-proteasome system is essential for the productive entry of Japanese encephalitis virus, Virology, 2016, corresponding author.
(2) Structure-function relationship of the mammarenavirus envelope glycoprotein, Virologica Sinica, 2016, corresponding author.
(3) Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus, journal of virology, 2016, 5th author.
(4) Subcellular quantitative proteomic analysis reveals host proteins involved in human cytomegalovirus infection, Biochim Biophys Acta., 2015, 3rd author.
(5) Peptide inhibitor of Japanese encephalitis virus infection targeting envelope protein domain III, Antiviral Res, 2014, corresponding author.
(6) Japanese encephalitis virus activates autophagy as a viral immune evasion strategy., PLoS One, 2013, corresponding author.
(7) Blocking peptides against HBV: preS1 protein selected from a phage display library, Biochem Biophys Res Commun, 2011, first author.
(8) Dual temperature/pH-sensitive drug delivery of poly(N-isopropylacrylamide-co-acrylic acid) nanogels conjugated with doxorubicin for potential application in tumor hyperthermia therapy, Colloids Surf B Biointerfaces, 2011, 2nd author.
(9) Protective effect of PEGylation against poly(amidoamine) dendrimer-induced hemolysis of human red blood cells, J Biomed Mater Res B Appl Biomater, 2010, first author.
(10) The decrease of PAMAM dendrimer-induced cytotoxicity by PEGylation via attenuation of oxidative stress, Nanotechnology, 2009, first author.


Patents
The usage of F and Fc fusion protein of RSV. 2013, No: 2013100900443


Conferences

(1)ubiquitin-proteasome system is essential for the productive entry of Japanese encephalitis virus   2016-04-18
(2)Japanese encephalitis virus activates autophagy as a viral immune evasion    Jin Rui   2013-07-12


Students

已指导学生

陈黎曼  硕士研究生  085238-生物工程  

王培林  硕士研究生  071010-生物化学与分子生物学  

朱雪芹  硕士研究生  071005-微生物学