植物在生长过程中与环境微生物有密切的互作，其中包括病原微生物、有益微生物和其它微生物。病原微生物导致的病害是影响全球作物产量和食品安全的一大危害。植物病理学的一个经典定律-病害三角学说阐明了病原物致病不仅需要感病的宿主和有致病力的病原物，而且需要适宜的环境条件（如自然界中绝大多数植物病害的发生需要适宜的温度和湿度等）。本课题组以拟南芥和水稻等为研究对象，运用分子生物学、植物遗传学、生物化学、细胞生物学、生物信息学等多种手段，在植物-微生物-环境三者的互作机制开展研究工作。

   

071001-植物学

植物与微生物互作

2008-08--2014-04   美国密歇根州立大学   博士
2004-09--2008-06   中国农业大学   本科

博士

哲学博士(Ph.D.)

2014-04--2017-08    美国密歇根州立大学 博士后

2014-04~2017-07,美国密歇根州立大学, 博士后

   

植物生理与分子生物学

   

（1） Bessey Graduate Research Award, , 研究所（学校）, 2014
（2） Dissertation Continuation Fellowship, , 研究所（学校）, 2013

   

[1] Jingni Wu, Xiao Mei, Jinyu Zhang, Luhuan Ye, Yezhou Hu, Tao Chen, Yiping Wang, Yijing Zhang, Xiu-Fang Xin. CURLYLEAF modulates apoplast water status in Arabidopsis leaves. Plant Physiology[J]. 2023, [2] Minhang Yuan, Boying Cai, XiuFang Xin, Rosa LozanoDurn. Plant immune receptor pathways as a united front against pathogens. PLOS PATHOGENS[J]. 2023, 19(2): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9910753/.
[3] Hu, Yezhou, Ding, Yanxia, Cai, Boying, Qin, Xiaohui, Wu, Jingni, Yuan, Minhang, Wan, Shiwei, Zhao, Yang, Xin, XiuFang. Bacterial effectors manipulate plant abscisic acid signaling for creation of an aqueous apoplast. CELL HOST & MICROBE[J]. 2022, 30(4): 518-+, http://dx.doi.org/10.1016/j.chom.2022.02.002.
[4] Gong, Tianyu, Xin, XiuFang. Phyllosphere microbiota: Community dynamics and its interaction with plant hosts. JOURNAL OF INTEGRATIVE PLANT BIOLOGY[J]. 2021, 63(2): 297-304, https://www.webofscience.com/wos/woscc/full-record/WOS:000617301100004.
[5] Yuan, Minhang, Jiang, Zeyu, Bi, Guozhi, Nomura, Kinya, Liu, Menghui, Wang, Yiping, Cai, Boying, Zhou, JianMin, He, Sheng Yang, Xin, XiuFang. Pattern-recognition receptors are required for NLR-mediated plant immunity. NATURE[J]. 2021, 592(7852): 105-+, http://dx.doi.org/10.1038/s41586-021-03316-6.
[6] Yuan, Minhang, Ngou, Bruno Pok Man, Ding, Pingtao, XiuFan, Xin. PTI-ETI crosstalk: an integrative view of plant immunity. CURRENT OPINION IN PLANT BIOLOGYnull. 2021, 62: http://dx.doi.org/10.1016/j.pbi.2021.102030.
[7] Chen, Tao, Nomura, Kinya, Wang, Xiaolin, Sohrabi, Reza, Xu, Jin, Yao, Lingya, Paasch, Bradley C, Ma, Li, Kremer, James, Cheng, Yuti, Zhang, Li, Wang, Nian, Wang, Ertao, Xin, XiuFang, He, Sheng Yang. A plant genetic network for preventing dysbiosis in the phyllosphere. NATURE[J]. 2020, 580(7805): 653-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000529600500017.
[8] Xin, XiuFang, Kvitko, Brian, He, Sheng Yang. Pseudomonas syringae: what it takes to be a pathogen. NATURE REVIEWS MICROBIOLOGYnull. 2018, 16(5): 316-328, http://dx.doi.org/10.1038/nrmicro.2018.17.
[9] Xin, XiuFang, Nomura, Kinya, Aung, Kyaw, Velasquez, Andre C, Yao, Jian, Boutrot, Freddy, Chang, Jeff H, Zipfel, Cyril, He, Sheng Yang. Bacteria establish an aqueous living space in plants crucial for virulence. NATURE[J]. 2016, 539(7630): 524-+, http://dx.doi.org/10.1038/nature20166.
[10] 徐华强. Structural basis of JAZ-mediated repression of MYC transcription factors in jasmonate signaling. Nature. 2015, [11] Zhang, Li, Yao, Jian, Withers, John, Xin, XiuFang, Banerjee, Rahul, Fariduddin, Qazi, Nakamura, Yoko, Nomura, Kinya, Howe, Gregg A, Boland, Wilhelm, Yan, Honggao, He, Sheng Yang. Host target modification as a strategy to counter pathogen hijacking of the jasmonate hormone receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2015, 112(46): 14354-14359, https://www.webofscience.com/wos/woscc/full-record/WOS:000365170400071.
[12] Xin Xiufang. Pseudomonas syringae effector AvrE localizes to the host plasma membrane and down-regulates the expression of the NDR/HIN1-like 13 gene required for antibacterial immunity in Arabidopsis. Plant Physiology. 2015, [13] Xin, XiuFang, He, Sheng Yang, VanAlfen, NK. Pseudomonas syringae pv. tomato DC3000: A Model Pathogen for Probing Disease Susceptibility and Hormone Signaling in Plants. ANNUAL REVIEW OF PHYTOPATHOLOGY, VOL 51null. 2013, 51: 473-498, http://dx.doi.org/10.1146/annurev-phyto-082712-102321.
[14] Xin, XiuFang, Nomura, Kinya, Underwood, William, He, Sheng Yang. Induction and Suppression of PEN3 Focal Accumulation During Pseudomonas syringae pv. tomato DC3000 Infection of Arabidopsis. MOLECULAR PLANT-MICROBE INTERACTIONS[J]. 2013, 26(8): 861-867, https://doaj.org/article/247b1ae0be38464f98d13e9f2b737816.

Subcellular localization of Pseudomonas syringae pv. tomato effector proteins in plants, Springer New York, 2017-05, 第 2 作者

   

现指导学生

袁民航  博士研究生  071007-遗传学  

胡叶舟  硕士研究生  071007-遗传学  

蔡博莹  硕士研究生  071007-遗传学