基本信息

Alberto Macho  男  博导  中国科学院分子植物科学卓越创新中心(植物生理生态研究所)
电子邮件: alberto.macho@cemps.ac.cn
通信地址: 松江区辰花路3888号科研中心PSC9
邮政编码:201602

研究领域

植物与细菌相互作用研究

招生信息

   
招生专业
071010-生物化学与分子生物学
招生方向
植物与细菌性病原体的交互作用

教育背景

2005-01--2010-07   西班牙马拉加大学   博士
2004-09--2006-09   西班牙马拉加大学   硕士
1999-09--2004-09   西班牙马拉加大学   本科学士

工作经历

   
工作简历
2020-05~现在, 中国科学院分子植物科学卓越创新中心, 研究员
2015-01~2020-04,中国科学研究院上海生命科学研究院, 研究员
2011-02~2014-12,英国诺维奇塞恩斯伯里实验室, 博士后
2010-08~2011-01,西班牙马拉加大学, 博士后

教授课程

Plant-Bacteria Interaction
Salicylic Acid
Type III-secreted effectors
Plant Stress Biology

专利与奖励

   
奖励信息
(1) FEBS杰出青年科学家奖, 一等奖, 其他, 2015
(2) 获得FEBS长期博士后奖, 一等奖, 其他, 2011
(3) 马拉加大学杰出博士生奖, 一等奖, 研究所(学校), 2010
(4) EMBO 短期奖学金, 一等奖, 其他, 2008

出版信息

   
发表论文
[1] Alberto Macho, Pengcheng Wang, JianKang Zhu. Modification of the susceptibility gene TaPsIPK1‑a win‑win for wheat disease resistance and yield. 逆境生物学(英文)[J]. 2022, 2(1): 1-4, http://lib.cqvip.com/Qikan/Article/Detail?id=7108154720.
[2] Suhui Lv, Yu Yang, Gang Yu, Li Peng, Shuai Zheng, Sunil Kumar Singh, Juan Ignacio Vlchez, Richa Kaushal, Hailing Zi, Dian Yi, Yuhua Wang, Shaofan Luo, Xiaoxuan Wu, Ziwei Zuo, Weichang Huang, Renyi Liu, Jiamu Du, Alberto P Macho, Kai Tang, Huiming Zhang. Dysfunction of histone demethylase IBM1 in Arabidopsis causes autoimmunity and reshapes the root microbiome. THE ISME JOURNAL. 2022, 16(11): 2513-2524, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9561531/.
[3] Julian Dindas, Thomas A DeFalco, Gang Yu, Lu Zhang, Pascale David, Marta Bjornson, MarieChristine Thibaud, Valria Custdio, Gabriel Castrillo, Laurent Nussaume, Alberto P Macho, Cyril Zipfel. Direct inhibition of phosphate transport by immune signaling in Arabidopsis. CURRENT BIOLOGY. 2022, 32(2): 488-495.e5, http://dx.doi.org/10.1016/j.cub.2021.11.063.
[4] Yu, Gang, Derkacheva, Maria, Rufian, Jose S, Brillada, Carla, Kowarschik, Kathrin, Jiang, Shushu, Derbyshire, Paul, Ma, Miaomiao, DeFalco, Thomas A, Morcillo, Rafael J L, Stransfeld, Lena, Wei, Yali, Zhou, JianMin, Menke, Frank L H, Trujillo, Marco, Zipfel, Cyril, Macho, Alberto P. The Arabidopsis E3 ubiquitin ligase PUB4 regulates BIK1 and is targeted by a bacterial type-III effector. EMBO JOURNAL[J]. 2022, 41(23): http://dx.doi.org/10.15252/embj.2020107257.
[5] Rufian, Jose S, RuedaBlanco, Javier, LopezMarquez, Diego, Macho, Alberto P, Beuzon, Carmen R, RuizAlbert, Javier. The bacterial effector HopZ1a acetylates MKK7 to suppress plant immunity. NEW PHYTOLOGIST[J]. 2021, 231(3): 1138-1156, http://dx.doi.org/10.1111/nph.17442.
[6] Gang Yu, Liu Xian, Haiyan Zhuang, Alberto P Macho. SGT1 is not required for bacterial PAMP-triggered immunity. Molecular Plant Pathology[J]. 2021, [7] Liping Wang, Gang Yu, Alberto P Macho, Rosa LozanoDurn. Split-luciferase Complementation Imaging Assay to Study Protein-protein Interactions in Nicotiana benthamiana. BIO-PROTOCOL. 2021, 11(23): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678545/.
[8] Li, Zicong, Luo, Xiao, Ou, Yang, Jiao, Huijun, Peng, Li, Fu, Xing, Macho, Alberto P, Liu, Renyi, He, Yuehui. JASMONATE-ZIM DOMAIN proteins engage Polycomb chromatin modifiers to modulate Jasmonate signaling in Arabidopsis. MOLECULAR PLANT[J]. 2021, 14(5): 732-747, http://lib.cqvip.com/Qikan/Article/Detail?id=7105117296.
[9] Yu, Gang, Xian, Liu, Zhuang, Haiyan, Macho, Alberto P. SGT1 is not required for plant LRR-RLK-mediated immunity. MOLECULAR PLANT PATHOLOGY[J]. 2021, 22(1): 145-150, https://www.webofscience.com/wos/woscc/full-record/WOS:000588111400001.
[10] HoPlagaro, Tania, Morcillo, Rafael J L, TamayoNavarrete, Maria Isabel, Huertas, Raul, MolineroRosales, Nuria, LopezRaez, Juan Antonio, Macho, Alberto P, GarciaGarrido, Jose Manuel. DLK2 regulates arbuscule hyphal branching during arbuscular mycorrhizal symbiosis. NEW PHYTOLOGIST[J]. 2021, 229(1): 548-562, http://dx.doi.org/10.1111/nph.16938.
[11] Wenjia Yu, Alberto P Macho. A Fast and Easy Method to Study Ralstonia solanacearum Virulence upon Transient Gene Expression or Gene Silencing in Nicotiana benthamiana Leaves. BIO-PROTOCOL. 2021, 11(15): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376586/.
[12] RuizLopez, Noemi, PerezSancho, Jessica, Esteban del Valle, Alicia, Haslam, Richard P, Vanneste, Steffen, Catala, Rafael, PereaResa, Carlos, Van Damme, Daniel, GarciaHernandez, Selene, Albert, Armando, Vallarino, Jose, Lin, Jinxing, Friml, Jiri, Macho, Alberto P, Salinas, Julio, Rosado, Abel, Napier, Johnathan A, AmorimSilva, Vitor, Botella, Miguel A. Synaptotagmins at the endoplasmic reticulum-plasma membrane contact sites maintain diacylglycerol homeostasis during abiotic stress. PLANT CELL[J]. 2021, 33(7): 2431-2453, http://dx.doi.org/10.1093/plcell/koab122.
[13] Wang, Yaru, Zhao, Achen, Morcillo, Rafael J L, Yu, Gang, Xue, Hao, Rufian, Jose S, Sang, Yuying, Macho, Alberto P. A bacterial effector protein uncovers a plant metabolic pathway involved in tolerance to bacterial wilt disease. MOLECULAR PLANT[J]. 2021, 14(8): 1281-1296, http://dx.doi.org/10.1016/j.molp.2021.04.014.
[14] Xingang Wang, Min Ren, Danni Liu, Dabao Zhang, Cuijun Zhang, Zhaobo Lang, Alberto P Macho, Min Zhang, Jian-Kang Zhu. Large-scale eQTL identification in Arabidopsis reveals novel candidate regulators of immune responses and other processes. Journal of Integrative Plant Biology[J]. 2020, [15] Yali Wei, Alexandra Balaceanu, Jose S Rufian, Ccile Segonzac, Achen Zhao, Rafael J L Morcillo, Alberto P Macho. An immune receptor complex evolved in soybean to perceive a polymorphic bacterial flagellin. NATURE COMMUNICATIONS[J]. 2020, 11(1): 1-11, http://dx.doi.org/10.1038/s41467-020-17573-y.
[16] Lee, EunKyoung, Santana, Brenda Vila Nova, Samuels, Elizabeth, BenitezFuente, Francisco, Corsi, Erica, Botella, Miguel A, PerezSancho, Jessica, Vanneste, Steffen, Friml, Jiri, Macho, Alberto, Azevedo, Aristea Alves, Rosado, Abel. Rare earth elements induce cytoskeleton-dependent and PI4P-associated rearrangement of SYT1/SYT5 endoplasmic reticulum-plasma membrane contact site complexes in Arabidopsis. JOURNAL OF EXPERIMENTAL BOTANY[J]. 2020, 71(14): 3986-3998, https://www.webofscience.com/wos/woscc/full-record/WOS:000553125400007.
[17] Xian, Liu, Yu, Gang, Wei, Yali, Rufian, Jose S, Li, Yansha, Zhuang, Haiyan, Xue, Hao, Morcillo, Rafael Jl, Macho, Alberto P. A Bacterial Effector Protein Hijacks Plant Metabolism to Support Pathogen Nutrition. CELL HOST & MICROBE[J]. 2020, 28(4): 548-+, http://dx.doi.org/10.1016/j.chom.2020.07.003.
[18] Yuying Sang, Wenjia Yu, Haiyan Zhuang, Yali Wei, Lida Derevnina, Gang Yu, Jiamin Luo, Alberto P Macho. Intra-strain Elicitation and Suppression of Plant Immunity by Ralstonia solanacearum Type-III Effectors in Nicotiana benthamiana. PLANT COMMUNICATIONS. 2020, 1(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747989/.
[19] Morcillo, Rafael J L, Zhao, Achen, TamayoNavarrete, Maria, I, GarciaGarrido, Jose M, Macho, Alberto P. Tomato Root Transformation Followed by Inoculation with Ralstonia Solanacearum for Straightforward Genetic Analysis of Bacterial Wilt Disease. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS[J]. 2020, http://dx.doi.org/10.3791/60302.
[20] Yu, Gang, Xian, Liu, Xue, Hao, Yu, Wenjia, Rufian, Jose S, Sang, Yuying, Morcillo, Rafael J L, Wang, Yaru, Macho, Alberto P. A bacterial effector protein prevents MAPK-mediated phosphorylation of SGT1 to suppress plant immunity. PLOS PATHOGENS[J]. 2020, 16(9): https://doaj.org/article/983aaf6438284844802ae45a34e944a4.
[21] Alberto Macho. A versatile method for tomato root transformation followed by inoculation with Ralstonia solanacearum allows straightforward genetic analysis for the study of bacterial wilt disease. JOURNALOFVISUALIZEDEXPERIMENTS. 2020, [22] Morcillo, Rafael J L, Singh, Sunil K, He, Danxia, An, Guo, Vilchez, Juan, I, Tang, Kai, Yuan, Fengtong, Sun, Yazhou, Shao, Chuyang, Zhang, Song, Yang, Yu, Liu, Xiaomin, Dang, Yashan, Wang, Wei, Gao, Jinghui, Huang, Weichang, Lei, Mingguang, Song, ChunPeng, Zhu, JianKang, Macho, Alberto P, Pare, Pual W, Zhang, Huiming. Rhizobacterium-derived diacetyl modulates plant immunity in a phosphate-dependent manner. EMBO JOURNAL[J]. 2020, 39(2): https://www.webofscience.com/wos/woscc/full-record/WOS:000500576700001.
[23] Alberto Macho. Diacetyl determines plant-bacteria relation via phosphate-dependent modulation of plant immunity. EMBO Journal. 2020, [24] Wang, Pengcheng, Hsu, ChuanChih, Du, Yanyan, Zhu, Peipei, Zhao, Chunzhao, Fu, Xing, Zhang, Chunguang, Paez, Juan Sebastian, Macho, Alberto P, Tao, W Andy, Zhu, JianKang. Mapping proteome-wide targets of protein kinases in plant stress responses. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2020, 117(6): 3270-3280, https://www.webofscience.com/wos/woscc/full-record/WOS:000513898000071.
[25] Xue, Hao, LozanoDuran, Rosa, Macho, Alberto P. Insights into the Root Invasion by the Plant Pathogenic Bacterium Ralstonia solanacearum. PLANTS-BASELnull. 2020, 9(4): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000539578900110.
[26] Sabbagh, Cyrus Raja Rubenstein, Carrere, Sebastien, Lonjon, Fabien, Vailleau, Fabienne, Macho, Alberto P, Genin, Stephane, Peeters, Nemo. Pangenomic type III effector database of the plant pathogenic Ralstonia spp.. PEERJ[J]. 2019, 7: https://doaj.org/article/3bf7271f22ec45a18f77906a39dbd58e.
[27] Macho, Alberto P, LozanoDuran, Rosa. Molecular dialogues between viruses and receptor-like kinases in plants. MOLECULAR PLANT PATHOLOGYnull. 2019, 20(9): 1191-1195, https://www.webofscience.com/wos/woscc/full-record/WOS:000483704700003.
[28] Duan, Jianli, Lee, Keun Pyo, Dogra, Vivek, Zhang, Siyuan, Liu, Kaiwei, CaceresMoreno, Carlos, Lv, Shanshan, Xing, Weiman, Kato, Yusuke, Sakamoto, Wataru, Liu, Renyi, Macho, Alberto P, Kim, Chanhong. Impaired PSII Proteostasis Promotes Retrograde Signaling via Salicylic Acid. PLANT PHYSIOLOGY[J]. 2019, 180(4): 2182-2197, https://www.webofscience.com/wos/woscc/full-record/WOS:000477951400035.
[29] Wang, Yuanzheng, Li, Yansha, RosesDiaz, Tabata, CaceresMoreno, Carlos, LozanoDuran, Rosa, Macho, Alberto P. The IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING 9 Protein Is a Regulator of Basal Immunity in Arabidopsis thaliana. MOLECULAR PLANT-MICROBE INTERACTIONS[J]. 2019, 32(1): 65-75, https://www.webofscience.com/wos/woscc/full-record/WOS:000460413600008.
[30] AmorimSilva, Vitor, GarciaMoreno, Alvaro, Castillo, Araceli G, Lakhssassi, Naoufal, del Valle, Alicia Esteban, PerezSancho, Jessica, Li, Yansha, Pose, David, PerezRodriguez, Josefa, Lin, Jinxing, Valpuesta, Victoriano, Borsani, Omar, Zipfel, Cyril, Macho, Alberto P, Botella, Miguel A. TTL Proteins Scaffold Brassinosteroid Signaling Components at the Plasma Membrane to Optimize Signal Transduction in Arabidopsis. PLANT CELL[J]. 2019, 31(8): 1807-1828, https://www.webofscience.com/wos/woscc/full-record/WOS:000478959700014.
[31] Zheng, Xueao, Li, Xiaojing, Wang, Bingsen, Cheng, Dong, Li, Yanping, Li, Wenhao, Huang, Mengshu, Tan, Xiaodan, Zhao, Guozhen, Song, Botao, Macho, Alberto P, Chen, Huilan, Xie, Conghua. A systematic screen of conserved Ralstonia solanacearum effectors reveals the role of RipAB, a nuclear-localized effector that suppresses immune responses in potato. MOLECULAR PLANT PATHOLOGY[J]. 2019, 20(4): 547-561, https://www.webofscience.com/wos/woscc/full-record/WOS:000461896600007.
[32] Yu, Gang, Xian, Liu, Sang, Yuying, Macho, Alberto P. Cautionary notes on the use of Agrobacterium-mediated transient gene expression upon SGT1 silencing in Nicotiana benthamiana. NEW PHYTOLOGISTnull. 2019, 222(1): 14-17, https://www.webofscience.com/wos/woscc/full-record/WOS:000459928400004.
[33] Lourdes Rubio, Jordi DazGarca, Vtor AmorimSilva, Alberto P Macho, Miguel A Botella, Jos A Fernndez. Molecular Characterization of ZosmaNRT2, the Putative Sodium Dependent High-Affinity Nitrate Transporter of Zostera marina L.. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2019, 20(15): https://doaj.org/article/f72164d020274c71aa988dbace0e2e7f.
[34] Borja Garnelo Gmez, Dan Zhang, Tbata RosasDaz, Yali Wei, Alberto P Macho, Rosa LozanoDurn. The C4 Protein from Tomato Yellow Leaf Curl Virus Can Broadly Interact with Plant Receptor-Like Kinases. VIRUSES[J]. 2019, 11(11): https://doaj.org/article/11819e0ff40740809a29ac30f5ba8f60.
[35] Lee, Eunkyoung, Vanneste, Steffen, PerezSancho, Jessica, BenitezFuente, Francisco, Strelau, Matthew, Macho, Alberto P, Botella, Miguel A, Friml, Jiri, Rosado, Abel. Ionic stress enhances ER-PM connectivity via phosphoinositide-associated SYT1 contact site expansion in Arabidopsis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 116(4): 1420-1429, [36] Rufian, Jose S, Lucia, Ainhoa, RuedaBlanco, Javier, Zumaquero, Adela, Guevara, Carlos M, OrtizMartin, Inmaculada, RuizAldea, Gonzalo, Macho, Alberto P, Beuzon, Carmen R, RuizAlbert, Javier. Suppression of HopZ Effector-Triggered Plant Immunity in a Natural Pathosystem. FRONTIERS IN PLANT SCIENCE[J]. 2018, 9: https://doaj.org/article/42e220f505824ec48b813280d14b67ff.
[37] Sang, Yuying, Wang, Yaru, Ni, Hong, Cazale, AnneClaire, She, YiMin, Peeters, Nemo, Macho, Alberto P. The Ralstonia solanacearum type III effector RipAY targets plant redox regulators to suppress immune responses. MOLECULAR PLANT PATHOLOGY[J]. 2018, 19(1): 129-142, http://dx.doi.org/10.1111/mpp.12504.
[38] Perraki, Artemis, DeFalco, Thomas A, Derbyshire, Paul, Avila, Julian, Sere, David, Sklenar, Jan, Qi, Xingyun, Stransfeld, Lena, Schwessinger, Benjamin, Kadota, Yasuhiro, Macho, Alberto P, Jiang, Shushu, Couto, Daniel, Torii, Keiko U, Menke, Frank L H, Zipfel, Cyril. Phosphocode-dependent functional dichotomy of a common co-receptor in plant signalling. NATURE[J]. 2018, 561(7722): 248-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000444437900045.
[39] Zhao, Yang, Zhang, Zhengjing, Gao, Jinghui, Wang, Pengcheng, Hu, Tao, Wang, Zegang, Hou, YuehJu, Wan, Yizhen, Liu, Wenshan, Xie, Shaojun, Lu, Tianjiao, Xue, Liang, Liu, Yajie, Macho, Alberto P, Tao, W Andy, Bressan, Ray A, Zhu, JianKang. Arabidopsis Duodecuple Mutant of PYL ABA Receptors Reveals PYL Repression of ABA-Independent SnRK2 Activity. CELL REPORTS[J]. 2018, 23(11): 3340-+, http://dx.doi.org/10.1016/j.celrep.2018.05.044.
[40] Wei, Yali, CaceresMoreno, Carlos, JimenezGongora, Tamara, Wang, Keke, Sang, Yuying, LozanoDuran, Rosa, Macho, Alberto P. The Ralstonia solanacearum csp22 peptide, but not flagellin-derived peptides, is perceived by plants from the Solanaceae family. PLANT BIOTECHNOLOGY JOURNAL[J]. 2018, 16(7): 1349-1362, https://www.webofscience.com/wos/woscc/full-record/WOS:000435096400009.
[41] Alberto Macho. Analysis of PAMP-triggered ROS Burst in Plant Immunity. Methods in Molecular Biology. 2017, [42] Alberto Macho. Genome sequencing and analysis of Ralstonia solanacearum phylotype I strains FJAT-91, FJAT-452 and FJAT-462 isolated from tomato, eggplant, and chilli pepper in China. Standards in Genomic Sciences. 2017, [43] Wei, Yali, Sang, Yuying, Macho, Alberto P. The Ralstonia solanacearum Type III Effector RipAY Is Phosphorylated in Plant Cells to Modulate Its Enzymatic Activity. FRONTIERS IN PLANT SCIENCE[J]. 2017, 8: https://doaj.org/article/19e07482ba2d4a77880ca8c820561917.
[44] Jiang, Gaofei, Wei, Zhong, Xu, Jin, Chen, Huilan, Zhang, Yong, She, Xiaoman, Macho, Alberto P, Ding, Wei, Liao, Boshou. Bacterial Wilt in China: History, Current Status, and Future Perspectives. FRONTIERS IN PLANT SCIENCEnull. 2017, 8: https://doaj.org/article/6d67bd9ef4864cf396ea349cabd6adf8.
[45] Puigvert, Marina, GuarischiSousa, Rodrigo, Zuluaga, Paola, Coll, Nuria S, Macho, Alberto P, Setubal, Joao C, Valls, Marc. Transcriptomes of Ralstonia solanacearum during Root Colonization of Solanum commersonii. FRONTIERS IN PLANT SCIENCE[J]. 2017, 8: https://www.webofscience.com/wos/woscc/full-record/WOS:000396760400001.
[46] Alberto Macho. Confocal microscopy reveals in planta dynamic interactions between pathogenic, avirulent and non-pathogenic Pseudomonas syringae strains. . Molecular Plant Pathology. 2017, [47] Sun, Yidan, Wang, Keke, CaceresMoreno, Carlos, Jia, Wei, Chen, Aojun, Zhang, Heng, Liu, Renyi, Macho, Alberto P. Genome sequencing and analysis of Ralstonia solanacearum phylotype I strains FJAT-91, FJAT-452 and FJAT-462 isolated from tomato, eggplant, and chili pepper in China. STANDARDS IN GENOMIC SCIENCES[J]. 2017, 12(1): http://dx.doi.org/10.1186/s40793-017-0241-7.
[48] Alberto Macho. The Ralstonia solanacearum type-III effector RipAY targets plant redox regulators to suppress immune responses. Molecular Plant Pathology. 2016, [49] Alberto Macho. Competitive Index: Mixed Infection-Based Virulence Assays for Genetic Analysis in Pseudomonas syringae-Plant Interactions. Methods in Molecular Biology. 2016, [50] Tbata RosasDaz, Alberto P Macho, Carmen R Beuzn, Rosa LozanoDurn, Eduardo R Bejarano. The C2 Protein from the Geminivirus Tomato Yellow Leaf Curl Sardinia Virus Decreases Sensitivity to Jasmonates and Suppresses Jasmonate-Mediated Defences. PLANTS[J]. 2016, 5(1): https://doaj.org/article/193f4fd008c94755aae64e4f8420b836.
[51] Alberto Macho. Immunoprecipitation of Plasma Membrane Receptor-Like Kinases for Identification of Phosphorylation Sites and Associated Proteins. Methods in Molecular Biology. 2016, [52] Castro, Pedro Humberto, Couto, Daniel, Freitas, Sara, Verde, Nuno, Macho, Alberto P, Huguet, Stephanie, Botella, Miguel Angel, RuizAlbert, Javier, Tavares, Rui Manuel, Bejarano, Eduardo Rodriguez, Azevedo, Herlander. SUMO proteases ULP1c and ULP1d are required for development and osmotic stress responses in Arabidopsis thaliana. PLANT MOLECULAR BIOLOGY[J]. 2016, 92(1-2): 143-159, http://dx.doi.org/10.1007/s11103-016-0500-9.
[53] Macho, Alberto P. Subversion of plant cellular functions by bacterial type-III effectors: beyond suppression of immunity. NEW PHYTOLOGISTnull. 2016, 210(1): 51-57, http://dx.doi.org/10.1111/nph.13605.
[54] Alberto Macho. Targeting of PRR-triggered immunity by type-III effectors from plant pathogenic bacteria. Current Opinion in Microbiology. 2015, [55] Macho, Alberto P, LozanoDuran, Rosa, Zipfel, Cyril. Importance of tyrosine phosphorylation in receptor kinase complexes. TRENDS IN PLANT SCIENCEnull. 2015, 20(5): 269-272, http://dx.doi.org/10.1016/j.tplants.2015.02.005.
[56] Rufian, Jose S, Lucia, Ainhoa, Macho, Alberto P, OrozcoNavarrete, Begona, ArroyoMateos, Manuel, Bejarano, Eduardo R, Beuzon, Carmen R, RuizAlbert, Javier. Auto-acetylation on K289 is not essential for HopZ1a-mediated plant defense suppression. FRONTIERS IN MICROBIOLOGY[J]. 2015, 6: https://doaj.org/article/265617a9855e4773b8ab5b3e4be5f3b5.
[57] Macho, Alberto P, Zipfel, Cyril. Plant PRRs and the Activation of Innate Immune Signaling. MOLECULAR CELLnull. 2014, 54(2): 263-272, http://dx.doi.org/10.1016/j.molcel.2014.03.028.
[58] Macho, Alberto P, Schwessinger, Benjamin, Ntoukakis, Vardis, Brutus, Alexandre, Segonzac, Cecile, Roy, Sonali, Kadota, Yasuhiro, Oh, ManHo, Sklenar, Jan, Derbyshire, Paul, LozanoDuran, Rosa, Malinovsky, Frederikke Gro, Monaghan, Jacqueline, Menke, Frank L, Huber, Steven C, He, Sheng Yang, Zipfel, Cyril. A Bacterial Tyrosine Phosphatase Inhibits Plant Pattern Recognition Receptor Activation. SCIENCE[J]. 2014, 343(6178): 1509-1512, https://www.webofscience.com/wos/woscc/full-record/WOS:000333471000047.
[59] Segonzac, Cecile, Macho, Alberto P, Sanmartin, Maite, Ntoukakis, Vardis, SanchezSerrano, Jose Juan, Zipfel, Cyril. Negative control of BAK1 by protein phosphatase 2A during plant innate immunity. EMBO JOURNAL[J]. 2014, 33(18): 2069-2079, http://dx.doi.org/10.15252/embj.201488698.
[60] Sun, Yadong, Li, Lei, Macho, Alberto P, Han, Zhifu, Hu, Zehan, Zipfel, Cyril, Zhou, JianMin, Chai, Jijie. Structural Basis for flg22-Induced Activation of the Arabidopsis FLS2-BAK1 Immune Complex. SCIENCE[J]. 2013, 342(6158): 624-628, http://dx.doi.org/10.1126/science.1243825.
[61] LozanoDuran, Rosa, Macho, Alberto P, Boutrot, Freddy, Segonzac, Cecile, Somssich, Imre E, Zipfel, Cyril. The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth. ELIFE[J]. 2013, 2: https://doaj.org/article/7c7b0e8ce51d4f6a877274149917edd4.
[62] Macho, Alberto P, Zumaquero, Adela, GonzalezPlaza, Juan J, OrtizMartin, Inmaculada, Rufian, Jose S, Beuzon, Carmen R. Genetic Analysis of the Individual Contribution to Virulence of the Type III Effector Inventory of Pseudomonas syringae pv. phaseolicola. PLOS ONE[J]. 2012, 7(4): https://doaj.org/article/c54c98b2aa1848029e293a2ef305a87e.
[63] Macho, Alberto P, Boutrot, Freddy, Rathjen, John P, Zipfel, Cyril. ASPARTATE OXIDASE Plays an Important Role in Arabidopsis Stomatal Immunity. PLANT PHYSIOLOGY[J]. 2012, 159(4): 1845-1856, https://www.webofscience.com/wos/woscc/full-record/WOS:000307236700041.
[64] Macho, Alberto P, Guidot, Alice, Barberis, Patrick, Beuzon, Carmen R, Genin, Stephane. A Competitive Index Assay Identifies Several Ralstonia solanacearum Type III Effector Mutant Strains with Reduced Fitness in Host Plants. MOLECULAR PLANT-MICROBE INTERACTIONS[J]. 2010, 23(9): 1197-1205, http://dx.doi.org/10.1094/MPMI-23-9-1197.
[65] Alberto Macho. Approaching the role of the type III effector inventory of Pseudomonas syringae pv. phaseolicola 1448a in the interaction with the plant. Journal of Bacteriology. 2010, [66] OrtizMartin, Inmaculada, Thwaites, Richard, Macho, Alberto P, Mansfield, John W, Beuzon, Carmen R. Positive Regulation of the Hrp Type III Secretion System in Pseudomonas syringae pv. phaseolicola. MOLECULAR PLANT-MICROBE INTERACTIONS[J]. 2010, 23(5): 665-681, https://www.webofscience.com/wos/woscc/full-record/WOS:000276845000013.
[67] Macho, Alberto P, Beuzon, Carmen R. Insights into plant immunity signaling The bacterial competitive index angle. PLANT SIGNALING & BEHAVIOR[J]. 2010, 5(12): 1590-1593, [68] Alberto Macho. The Pseudomonas syringae type III effector HopZ1a suppresses effector-triggered immunity. New Phytologist. 2010, [69] Macho, Alberto P, RuizAlbert, Javier, Tornero, Pablo, Beuzon, Carmen R. Identification of new type III effectors and analysis of the plant response by competitive index. MOLECULAR PLANT PATHOLOGY[J]. 2009, 10(1): 69-80, http://dx.doi.org/10.1111/j.1364-3703.2008.00511.x.
[70] Alberto Macho. Early detection of bean infection by Pseudomonas syringae in asymptomatic leaf areas using chlorophyll fluorescente imaging. Photosynthesis research. 2008, [71] Macho, Alberto P, Zumaquero, Adela, OrtizMartin, Inmaculada, Beuzon, Carmen R. Competitive index in mixed infections: a sensitive and accurate assay for the genetic analysis of Pseudomonas syringae-plant interactions. MOLECULAR PLANT PATHOLOGY[J]. 2007, 8(4): 437-450, http://dx.doi.org/10.1111/J.1364-3703.2007.00404.X.
[72] OrtizMartin, Inmaculada, Macho, Alberto P, Lambersten, Lotte, Ramos, Cayo, Beuzon, Carmen R. Suicide vectors for antibiotic marker exchange and rapid generation of multiple knockout mutants by allelic exchange in Gram-negative bacteria. JOURNAL OF MICROBIOLOGICAL METHODS[J]. 2006, 67(3): 395-407, http://dx.doi.org/10.1016/j.mimet.2006.04.011.
[73] Segonzac Cécile, Macho Alberto P, Sanmartín Maite, Ntoukakis Vardis, Sánchez-Serrano José Juan, Zipfel Cyril. Negative control of BAK1 by protein phosphatase 2A during plant innate immunity. THE EMBO JOURNAL. 33(18): 2069-2079, [74] Liu Xian, Gang Yu, Alberto P Macho, Caitilyn Allen. The GABA transaminase GabT is required for full virulence of Ralstonia solanacearum in tomato. MICROPUBLICATION BIOLOGY. 2021: 
发表著作
(1) Competitive Index in Mixed Infection: A Sensitive and Accurate Method to Quantify Growth of Pseudomonas syringae in Different Plants, in Pseudomonas syringae Pathovars and Related Pathogens, Springer, 2008-06, 第 1 作者
(2) Chlorophyll Fluorescence Imaging for Detection of Bean Response to Pseudomonas syringae in Asymptomatic Leaf Areas, in Pseudomonas syringae Pathovars and Related Pathogens, Springer, 2008-06, 第 4 作者

科研活动

   
科研项目
( 1 ) 植物细菌病原体毒性的激活机制研究, 主持, 国家级, 2016-01--2019-12
( 2 ) 中央**** 青年项目, 主持, 国家级, 2015-01--2018-12
( 3 ) 病原体侵染与植物营养代谢相互作用的机制研究, 主持, 部委级, 2018-06--2023-05
( 4 ) Engineering synthetic 14-3-3 proteins to achieve broad-spectrum disease resistance in plants, 主持, 研究所(学校), 2018-12--2021-11
( 5 ) 植物根系对病原细菌的天然免疫分子机制解析, 主持, 国家级, 2022-01--2025-12
参与会议
(1)The molecular interface between plants and Ralstonia solanacearum: beyond activation and suppression of immunity   2019-06-26
(2)An immune receptor complex evolved to perceive the polymorphic flagellin from Ralstonia solanacearum   2019-06-24
(3)Ralstonia solanacearum subverts plant metabolism to support bacterial nutrition and cause bacterial wilt disease   2019-06-19
(4)The molecular interface between plants and Ralstonia solanacearum: beyond activation and suppression of immunity   2018-08-01
(5)Deciphering the molecular interface between plants and bacterial pathogens.   2018-05-01
(6)Deciphering the subversion of plant cellular functions by Ralstonia solanacearum type-III effectors   2017-09-15
(7)Analyses of plant immunity and the disruption by bacterial effectors   2016-11-30
(8)current work on thé plant pathogen Ralstonia solanacearum   2016-07-05
(9)Characterizing bacterial type-III effectors to decipher the molecular interface between plants and bacterial pathogens   Alberto Macho   2016-01-10
(10)Bacterial type-III effectors and the suppression of plant immune signalling   Alberto Macho   2015-06-04
(11)A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation   Alberto Macho   2014-10-01
(12)A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation   Alberto Macho   2014-09-01
(13)Role of phosphorylation in the activation of plant innate immune receptors   Alberto Macho   2014-08-01
(14)A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation   Alberto Macho   2014-07-01
(15)Role of phosphorylation in surface immune receptor complexes and its targeting by a bacterial effector protein   Alberto Macho   2012-10-01
(16)The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunity   Alberto Macho   2012-07-15
(17)The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunity   Alberto Macho   2012-07-01
(18)The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunity   Alberto Macho   2012-05-01
(19)The Pseudomonas syringae type III effector HopZ1a suppresses effector-triggered immunity   Alberto Macho   2010-08-01

指导学生

已指导学生

王远征  博士研究生  071010-生物化学与分子生物学  

鲜刘  博士研究生  071010-生物化学与分子生物学  

王亚如  博士研究生  071010-生物化学与分子生物学  

罗佳敏  博士研究生  071010-生物化学与分子生物学  

魏雅丽  博士研究生  071010-生物化学与分子生物学  

薛好  硕士研究生  071010-生物化学与分子生物学  

现指导学生

于文佳  博士研究生  071010-生物化学与分子生物学  

刘昕  博士研究生  071010-生物化学与分子生物学  

陈玉姣  硕士研究生  071010-生物化学与分子生物学  

赵阿晨  博士研究生  071010-生物化学与分子生物学  

李蒙  硕士研究生  071010-生物化学与分子生物学  

董倩  硕士研究生  071001-植物学  

王文隽  硕士研究生  071007-遗传学  

戴雨沁  硕士研究生  071010-生物化学与分子生物学