基本信息
Alberto Macho  男  博导  中国科学院分子植物科学卓越创新中心(植物生理生态研究所)
电子邮件: alberto.macho@sibs.ac.cn
通信地址: 松江区辰花路3888号科研中心317A
邮政编码:
部门/实验室:逆境中心

研究领域

植物与细菌相互作用研究

招生信息

   
招生专业
071010-生物化学与分子生物学
招生方向
植物与细菌性病原体的交互作用

教育背景

2005-01--2010-07   西班牙马拉加大学   博士
2004-09--2006-09   西班牙马拉加大学   硕士
1999-09--2004-09   西班牙马拉加大学   本科学士
学历
   
学位
   

工作经历

   
工作简历
2015-01~现在, 中国科学研究院上海生命科学研究院, 研究员
2011-02~2014-12,英国诺维奇塞恩斯伯里实验室, 博士后
2010-08~2011-01,西班牙马拉加大学, 博士后
社会兼职
   

教授课程

Plant-Bacteria Interaction
Salicylic Acid
Type III-secreted effectors
Plant Stress Biology

专利与奖励

   
奖励信息
(1) FEBS杰出青年科学家奖, 一等奖, 其他, 2015
(2) 获得FEBS长期博士后奖, 一等奖, 其他, 2011
(3) 马拉加大学杰出博士生奖, 一等奖, 研究所(学校), 2010
(4) EMBO 短期奖学金, 一等奖, 其他, 2008
专利成果
   

出版信息

   
发表论文
(1) Impaired PSII proteostasis promotes retrograde signaling via salicylic acid, Plant Physiology, 2019, 其他(合作组作者)
(2) TTL proteins scaffold brassinosteroid signaling components at the plasma membrane to optimize signal transduction in Arabidopsis, The Plant Cell, 2019, 其他(合作组作者)
(3) Molecular dialogues between viruses and receptor-like kinases in plants, Molecular Plant Pathology, 2019, 通讯作者
(4) Ionic stress enhances ER-PM connectivity via phosphoinositide-associated SYT1 contact site expansion in Arabidopsis., PNAS, 2019, 第 6 作者
(5) A systematic screen of conserved R. solanacearum effectors reveals the role of RipAB, a nuclear-localized effector that suppresses immune responses in potato., Molecular Plant Pathology, 2019, 其他(合作组作者)
(6) Cautionary notes on the use of Agrobacterium-mediated transient expression upon SGT1 silencing in Nicotiana benthamiana, New Phytologist, 2019, 通讯作者
(7) The IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING 9 protein is a regulator of basal immunity in Arabidopsis thaliana, Molecular Plant-Microbe Interactions, 2019, 通讯作者
(8) Phosphocode-dependent functional dichotomy of the common co-receptor BAK1 in plant signaling, Nature, 2019, 其他(合作组作者)
(9) Suppression of HopZ effector-triggered plant immunity in a natural pathosystem, Frontiers in Plant Science, 2018, 第 8 作者
(10) Arabidopsis Duodecuple Mutant of PYL ABA Receptors Reveals PYL Repression of ABA-Independent SnRK2 Activity, Cell Reports, 2018, 其他(合作组作者)
(11) The Ralstonia solanacearum csp22 peptide, but not flagellin-derived peptides, is perceived by plants from the Solanaceae family, Plant Biotechnology Journal, 2018, 通讯作者
(12) Confocal microscopy reveals in planta dynamic interactions between pathogenic, avirulent and non-pathogenic Pseudomonas syringae strains. , Molecular Plant Pathology, 2017, 第 2 作者
(13) Transcriptomes of Ralstonia solanacearum during root colonization of Solanum commersonii, Frontiers in Plant Science, 2017, 第 5 作者
(14) Genome sequencing and analysis of Ralstonia solanacearum phylotype I strains FJAT-91, FJAT-452 and FJAT-462 isolated from tomato, eggplant, and chilli pepper in China, Standards in Genomic Sciences, 2017, 通讯作者
(15) Bacterial Wilt in China: history, current status and future perspectives, Frontiers in Plant Science, 2017, 第 7 作者
(16) The Ralstonia solanacearum type III effector RipAY is phosphorylated in plant cells to modulate its enzymatic activity, Frontiers in Plant Science, 2017, 通讯作者
(17) Analysis of PAMP-triggered ROS Burst in Plant Immunity, Methods in Molecular Biology, 2017, 通讯作者
(18) SUMO proteases ULP1c and ULP1d are required for development and osmotic stress responses in Arabidopsis thaliana, Plant Molecular Biology, 2016, 第 5 作者
(19) The Ralstonia solanacearum type-III effector RipAY targets plant redox regulators to suppress immune responses, Molecular Plant Pathology, 2016, 通讯作者
(20) The C2 Protein from the Geminivirus Tomato Yellow Leaf Curl Sardinia Virus Decreases Sensitivity to Jasmonates and Suppresses Jasmonate-Mediated Defences, Plants, 2016, 第 2 作者
(21) Competitive Index: Mixed Infection-Based Virulence Assays for Genetic Analysis in Pseudomonas syringae-Plant Interactions, Methods in Molecular Biology, 2016, 第 1 作者
(22) Immunoprecipitation of Plasma Membrane Receptor-Like Kinases for Identification of Phosphorylation Sites and Associated Proteins, Methods in Molecular Biology, 2016, 第 2 作者
(23) Subversion of plant cellular functions by bacterial type-III effectors: beyond suppression of immunity, New Phytologist, 2016, 第 1 作者
(24) Targeting of PRR-triggered immunity by type-III effectors from plant pathogenic bacteria, Current Opinion in Microbiology, 2015, 第 1 作者
(25) Importance of tyrosine phosphorylation in receptor kinase complexes, Trends in Plant Science, 2015, 通讯作者
(26) Auto-acetylation on K289 is not essential for HopZ1a-mediated plant defense suppression, Frontiers in Microbiology, 2015, 第 3 作者
(27) Plant PRRs and the activation of innate immune signaling, Molecular Cell, 2014, 第 1 作者
(28) A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation, Science, 2014, 第 1 作者
(29) Negative control of BAK1 by Protein Phosphatase 2A during plant innate immunity, EMBO Journal, 2014, 第 2 作者
(30) The transcriptional regulator BZR1 mediates trade-off between plant innate immunity and growth, eLife, 2013, 第 2 作者
(31) Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex, Science, 2013, 第 3 作者
(32) Aspartate Oxidase plays an important role in Arabidopsis stomatal immunity, Plant Physiology, 2012, 第 1 作者
(33) Genetic analysis of the individual contribution to virulence of the type III effector inventory of Pseudomonas syringae pv. Phaseolicola, PLoS One, 2012, 第 1 作者
(34) Insights into plant immunity signaling: The bacterial competitive index angle, Plant Signaling & Behavior, 2010, 第 1 作者
(35) The Pseudomonas syringae type III effector HopZ1a suppresses effector-triggered immunity, New Phytologist, 2010, 第 1 作者
(36) A competitive index assay identifies several Ralstonia solanacearum Type III effector mutant strains with reduced fitness in host plants, Molecular Plant-Microbe Interactions, 2010, 第 1 作者
(37) Approaching the role of the type III effector inventory of Pseudomonas syringae pv. phaseolicola 1448a in the interaction with the plant, Journal of Bacteriology, 2010, 第 2 作者
(38) Positive regulation of the Hrp type III secretion system in Pseudomonas syringae pv. Phaseolicola, Molecular Plant-Microbe Interactions, 2010, 第 3 作者
(39) Identification of new type III effectors and analysis of the plant response by competitive index, Molecular Plant Pathology, 2009, 第 1 作者
(40) Early detection of bean infection by Pseudomonas syringae in asymptomatic leaf areas using chlorophyll fluorescente imaging, Photosynthesis research, 2008, 第 4 作者
(41) Competitive index in mixed infections: a sensitive and accurate assay for the genetic analysis of Pseudomonas syringae-plant interactions, Molecular Plant Pathology, 2007, 第 1 作者
(42) Suicide vectors for antibiotic marker exchange and rapid generation of multiple knockout mutants by allelic exchange in Gram-negative bacteria, Journal of Microbiological Methods, 2006, 第 2 作者
发表著作
(1) Competitive Index in Mixed Infection: A Sensitive and Accurate Method to Quantify Growth of Pseudomonas syringae in Different Plants, in Pseudomonas syringae Pathovars and Related Pathogens, Springer, 2008-06, 第 1 作者
(2) Chlorophyll Fluorescence Imaging for Detection of Bean Response to Pseudomonas syringae in Asymptomatic Leaf Areas, in Pseudomonas syringae Pathovars and Related Pathogens, Springer, 2008-06, 第 4 作者

科研活动

   
科研项目
( 1 ) 植物细菌病原体毒性的激活机制研究, 主持, 国家级, 2016-01--2019-12
( 2 ) 中央**** 青年项目, 主持, 国家级, 2015-01--2018-12
( 3 ) 病原体侵染与植物营养代谢相互作用的机制研究, 主持, 部委级, 2018-06--2023-05
参与会议
(1)The molecular interface between plants and Ralstonia solanacearum: beyond activation and suppression of immunity   2019-06-26
(2)An immune receptor complex evolved to perceive the polymorphic flagellin from Ralstonia solanacearum   2019-06-24
(3)Ralstonia solanacearum subverts plant metabolism to support bacterial nutrition and cause bacterial wilt disease   2019-06-19
(4)The molecular interface between plants and Ralstonia solanacearum: beyond activation and suppression of immunity   2018-08-01
(5)Deciphering the molecular interface between plants and bacterial pathogens.   2018-05-01
(6)Deciphering the subversion of plant cellular functions by Ralstonia solanacearum type-III effectors   2017-09-15
(7)Analyses of plant immunity and the disruption by bacterial effectors   2016-11-30
(8)current work on thé plant pathogen Ralstonia solanacearum   2016-07-05
(9)Characterizing bacterial type-III effectors to decipher the molecular interface between plants and bacterial pathogens   Alberto Macho   2016-01-10
(10)Bacterial type-III effectors and the suppression of plant immune signalling   Alberto Macho   2015-06-04
(11)A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation   Alberto Macho   2014-10-01
(12)A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation   Alberto Macho   2014-09-01
(13)Role of phosphorylation in the activation of plant innate immune receptors   Alberto Macho   2014-08-01
(14)A bacterial tyrosine phosphatase inhibits plant pattern recognition receptor activation   Alberto Macho   2014-07-01
(15)Role of phosphorylation in surface immune receptor complexes and its targeting by a bacterial effector protein   Alberto Macho   2012-10-01
(16)The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunity   Alberto Macho   2012-07-15
(17)The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunity   Alberto Macho   2012-07-01
(18)The novel short LRR-RK SEL is a positive regulator of PAMP-triggered immunity   Alberto Macho   2012-05-01
(19)The Pseudomonas syringae type III effector HopZ1a suppresses effector-triggered immunity   Alberto Macho   2010-08-01

合作情况

   
项目协作单位
   

指导学生

已指导学生

王远征  博士研究生  071010-生物化学与分子生物学  

现指导学生

鲜刘  博士研究生  071010-生物化学与分子生物学  

王亚如  博士研究生  071010-生物化学与分子生物学  

罗佳敏  博士研究生  071010-生物化学与分子生物学  

魏雅丽  博士研究生  071010-生物化学与分子生物学  

薛好  硕士研究生  071010-生物化学与分子生物学  

刘昕  硕士研究生  0710J3-生物信息学  

于文佳  博士研究生  071010-生物化学与分子生物学  

赵阿晨  硕士研究生  071007-遗传学