My research focus on stem cell, epigenetic regulation and aging process.

Ph.D.  GIBH

Master  Nankai University

Postdoc     University of North Carolina at Chapel Hill

Research scientist    Yale University

Ressociate research  at GIBH from 2010 to 2012.

1.  Wu, T.P., T. Wang, M.G. Seetin, Y. Lai, S. Zhu, K. Lin, Y. Liu, S.D. Byrum, S.G. Mackintosh, M. Zhong, A. Tackett, G. Wang, L.S. Hon, G. Fang, J.A. Swenberg, and A.Z. Xiao. DNA methylation on N(6)-adenine in mammalian embryonic stem cells. Nature. 2016. 532:329-333.

 

2.  Chen K, Long Q, Wang T, Zhao D, Zhou Y, Qi J, Wu Y, Li S, Chen C, Zeng X, Yang J, Zhou Z, Qin W, Liu X, Li Y, Huang X, Qin D, Chen J, Pan G, Scholer HR, Xu G, Pei D. Gadd45a is a heterochromatin relaxer that enhances iPS cell generation. EMBO Rep,2016.17: 1641-1656

 

3. Esteban, M.A. *, Wang, T. *, Qin, B. *, Yang, J., Qin, D., Cai, J., Li, W., Weng, Z., Chen, J., Ni, S., Chen, K., Li, Y., Liu, X., Xu, J., Zhang, S., Li, F., He, W., Labuda, K., Song, Y., Peterbauer, A., Wolbank, S., Redl, H., Zhong, M., Cai, D., Zeng, L., and Pei, D. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell, 2010. 6(1): 71-79. (*Contributed equally)

4. Wang, T., Chen, K., Zeng, X., Yang, J., Wu, Y., Shi, X., Qin, B., Zeng, L., Esteban, M.A., Pan, G., and Pei, D. The histone demethylases   Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. Cell Stem Cell, 2011. 9(6): 575-587.

 

        5. Chen, J., Liu, H., Liu, J., Qi, J., Wei, B., Yang, J., Liang, H., Chen, Y., Wu, Y., Guo, L., Zhu, J., Zhao, X., Peng, T., Zhang, Y., Chen, S., Li, X.,                Li, D., Wang, T., and Pei, D. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet, 2013. 45(1): 34-42.

现指导学生

付雨栋  博士研究生  071008-发育生物学