基本信息
陈建军  男  硕导  中国科学院武汉病毒研究所
电子邮件: chenjj126@126.com
通信地址: 武昌小洪山中区44号
邮政编码:

研究领域

1、流感病毒在家禽和野鸟中的流行趋势、遗传规律


2、流感病毒在不同宿主中致病力差异的影响因素分析


3、设计和评价具有广谱抗流感病毒作用的通用疫苗


招生信息

   
招生专业
071005-微生物学
招生方向
流感病毒

教育背景

   
学历

l 1996.9-2000.6 湖南师范大学生科院   生物教育专业 学士学位

l 2000.9-2003.6 湖南师范大学生科院   生物化学与分子生物学专业 硕士学位

l 2005.9-2008.6 中国科学院武汉病毒所   微生物专业 博士学位

l 2011.62011.10 美国Emory大学 微生物与免疫学系 博士后


学位
博士学位

工作经历

l 2003.7-2005.12 中科院武汉病毒所流感病毒学科组   实习研究员

l 2005.12-2010.12 中科院武汉病毒所流感病毒学科组   助理研究员

l 2010.12      中科院武汉病毒所流感病毒学科组 副研究员


工作简历
2010-09~现在, 中科院武汉病毒所, 副研究员
社会兼职
   

教授课程

   

专利与奖励

   
奖励信息
   
专利成果
( 1 ) 检测甲型H1N1病毒抗原的免疫检测试剂, 发明, 2010, 第 2 作者, 专利号: ZL201010501551.8

出版信息

   
发表论文
(1) A 3-year follow-up study of the seroprevalence of antibodies to avian influenza A H5, H6, H7 and H10 viruses among the general population of Wuhan, China, J Clin Virol, 2016, 通讯作者
(2) Novel avian influenza A (H5N6) viruses isolated in migratory waterfowl before the first human case reported in China, 2014, Sci Rep, 2016, 通讯作者
(3) Highly pathogenic avian influenza H5N1 Clade 2.3.2.1c virus in migratory birds, 2014-2015, Virol Sin, 2016, 第 1 作者
(4) Two Novel Reassortants of Avian Influenza A(H5N6) Virus in China, J Gen Virol, 2015, 通讯作者
(5) Bifunctional magnetic nanobeads for sensitive detection of avian influenza A (H7N9) virus based on immunomagnetic separation and enzyme-induced metallization, Biosens Bioelectron, 2015, 通讯作者
(6) Biometallization-Based Electrochemical Magnetoimmunosensing Strategy for Avian Influenza A (H7N9) Virus Particle Detection, Chem Asian J, 2015, 通讯作者
(7) Rapid and Quantitative Detection of Avian Influenza A(H7N9) Virions in Complex Matrices Based on Combined Magnetic Capture and Quantum Dot Labeling, Small, 2015, 通讯作者
(8) Serological study of antibodies to influenza A viruses among general population in Wuhan city China, Journal of Clinical Virology, 2014, 通讯作者
(9) Genotype Diversity of H9N2 Viruses Isolated from Wild Birds and Chickens in Hunan Province, China, PLoS One, 2014, 通讯作者
(10)  An adjuvanted inactivated murine cytomegalovirus (MCMV) vaccine induces potent and long-term protective immunity against a lethal challenge with virulent MCMV, BMC Infect Dis, 2014, 通讯作者
(11) Perpetuation of H5N1 and H9N2 avian influenza viruses in natural water bodies, J Gen Virol, 2014, 第 3 作者
(12) Comparative analysis of antibody induction and protection against influenza virus infection by DNA immunization with HA, HAe, and HA1 in mice, Arch Virol, 2014, 通讯作者
(13)  Evaluation of neutralizing efficacy of monoclonal antibodies specific for 2009 pandemic H1N1 influenza A virus in vitro and in vivo, Arch Virol, 2014, 通讯作者
(14) Serological study of antibodies to influenza A viruses among general population in Wuhan city China, J Clin Virol, 2014, 通讯作者
(15)  Avian influenza A(H7N9) virus screening in patients with fever and flu-like symptoms in a tertiary hospital in an area with confirmed cases, PLoS One, 2013, 第 3 作者
(16) Genome Sequence of a Reassortant H5N1 Avian Influenza Virus Isolated from Domestic Green-Winged Teal,  Genome Announc, 2013, 通讯作者
(17)  Enhanced protective efficacy of H5 subtype influenza vaccine with modification of the multibasic cleavage site of hemagglutinin in retroviral pseudotypes, Virol Sin, 2013, 第 2 作者
(18) Immunization with cytomegalovirus envelope glycoprotein M and glycoprotein N DNA vaccines can provide mice with complete protection against a lethal murine cytomegalovirus challenge, Virol Sin, 2013, 通讯作者
(19) Complete Genome Sequence of a Novel Reassortant H3N6 Avian Influenza Virus Isolated from Domestic Green-Winged Teal, Genome Announc, 2013, 通讯作者
(20) NA Proteins of Influenza A Viruses H1N1/2009, H5N1, and H9N2 Show Differential Effects on Infection Initiation, Virus Release, and Cell-Cell Fusion, PLoS One, 2013, 第 3 作者
(21) A second CRM1-dependent nuclear export signal in the influenza A virus NS2 protein contributes to the nuclear export of viral ribonucleoproteins,  J Virol, 2013, 通讯作者
(22) Characterization of low-pathogenic H6N6 avian influenza viruses in central China, Arch Virol, 2013, 通讯作者
(23) Are the H5N1 viruses prepared for inter-human transmission, Virol Sin, 2012, 通讯作者
(24) H5N1 Influenza Virus-like Particles Produced by Transient Expression in Mammalian Cells Induce Humoral and Cellular Immune Responses in Mice, Can J Microbiol, 2012, 第 2 作者
(25) Characterization of an H10N8 influenza virus isolated from Dongting lake wetland, Virol J, 2011, 第 4 作者
(26)  Effect of mucosal and systemic immunization with virus-like particles of severe acute respiratory syndrome coronavirus in mice, Immunology, 2010, 通讯作者
(27) A live bivalent influenza vaccine based on a H9N2 virus strain,  Vaccine, 2010, 第 4 作者
(28) Virus Research, 2009, 第 1 作者
(29) Virus Gene, 2009, 第 1 作者
(30)  Generation and evaluation of an H9N1 influenza vaccine derived by reverse genetics that allows utilization of a DIVA strategy for control of H9N2 avian influenza, Arch Virol, 2009, 第 4 作者
(31) A single immunization with HA DNA vaccine by electroporation induces early protection against H5N1 avian influenza virus challenge in mice, BMC Infect Dis, 2009, 第 4 作者
(32) Characterization of highly pathogenic H5N1 avian influenza viruses isolated from poultry markets in central China,  Virus Res, 2009, 第 1 作者
(33) Characterization of H5N1 influenza A viruses isolated from domestic green-winged teal, Virus Genes, 2009, 第 1 作者
(34) Electroporation at low voltages enables DNA vaccine to provide protection against a lethal H5N1 avian influenza virus challenge in mice, Intervirology, 2008, 第 3 作者
(35) Vaccination with hemagglutinin or neuraminidase DNA protects BALB/c mice against influenza virus infection in presence of maternal antibody, BMC Infect Dis, 2007, 第 1 作者
(36) Protection against influenza virus infection in BALB/c mice immunized with a single dose of neuraminidase-expressing DNAs by electroporation, Vaccine , 2005, 第 1 作者
(37) Maternal immunization with both hemagglutinin- and neuraminidase-expressing DNAs provides an enhanced protection against a lethal influenza virus challenge in infant and adult mice, DNA Cell Biol, 2005, 第 1 作者
发表著作
   

科研活动

   
科研项目
( 1 ) 湖北省传染病病毒谱流行规律研究, 主持, 国家级, 2012-01--2015-12
( 2 ) 湖北省鸟类禽流感病毒监测, 主持, 国家级, 2013-01--2017-12
( 3 ) 武汉沉湖湿地候鸟、留鸟和家禽间禽流感病毒的传播, 主持, 国家级, 2016-01--2019-12
参与会议
   

合作情况

   
项目协作单位
   

指导学生

已指导学生

熊超超  02  63228  

刘思玲  02  19183