硕士研究生

博士研究生

071009-细胞生物学
071010-生物化学与分子生物学
071007-遗传学

表观遗传学调控，转录调控，染色质重塑

2014-09--2017-06   北京大学   医学生物化学与分子生物学博士
2009-09--2014-07   北京大学   医学学士

2021-09--现在, 中科院上海有机化学研究所, 研究员、课题组长
2017-11--2021-07,哈佛大学医学院, 博士后

   

（1） Targeting RIPK1 kinase for modulating inflammation in human diseases, FRONTIERS IN IMMUNOLOGY, 2023, 第 1 作者，共同通讯作者 

（2） Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response, Cell Research, 2022, 第 1 作者，共同通讯作者 

（3） A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1, NATURE, 2020, 共同第 1 作者 

（4）The FOXN3-NEAT1-SIN3A repressor complex promotes progression of hormonally responsive breast cancer, JOURNAL OF CLINICAL INVESTIGATION, 2017, 第 1 作者 

（5） Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020

（6） ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner, CELL DEATH AND DIFFERENTIATION, 2019 

（7） TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging, CELL, 2018

（8） Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis, Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis, CELL RESEARCH, 2018

（9） ZNF516 suppresses EGFR by targeting the CtBP/LSD1/CoREST complex to chromatin, NATURE COMMUNICATIONS, 2017

（10） Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis, MOLECULAR CELL, 2017