083100-生物医学工程

生物医用水凝胶
新型抗菌药物开发
活性药物递送

2008-09--2013-06   南京大学   博士
2004-09--2008-06   中国药科大学   学士

   

2014-05~2015-04,韩国蔚山国立科技大学, 博士后
2014-01~2017-11,南京大学, 博士后
2008-09~2013-06,南京大学, 博士
2004-09~2008-06,中国药科大学, 学士

   

（ 1 ） 一种酰胺类化合物及其制备方法, 2022, 第 1 作者, 专利号: 202210056304.4

   

（1） Design, Synthesis and Molecular Docking of 1,3,4-Oxadiazole-2(3H)-thione Derivatives Containing 1,4-Benzodioxane Skeleton as Potential FabH Inhibitors, CHEMISTRY & BIODIVERSITY, 2023, 通讯作者
（2） Design, Synthesis and Antitumor Activity of FAK/PLK1 Dual Inhibitors with Quinazolinone as the Skeleton, CHEMISTRY & BIODIVERSITY, 2023, 通讯作者
（3） Design, synthesis and antibacterial activities of novel amide derivatives bearing dioxygenated rings as potential β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitors, Chemical and Pharmaceutical Bulletin, 2022, 第 1 作者
（4） Co2+-Mediated Hydrogels with Enhanced Mechanical Properties for Flexible Sensing, ACS APPLIED POLYMER MATERIALS, 2022, 通讯作者
（5） A mechanically adaptive "all-sugar" hydrogel for cell-laden injection, EUROPEAN POLYMER JOURNAL, 2022, 第 4 作者
（6） Thiazolidinedione: A provikeged scaffold for the design of anticancer agents, Curr. Top. Med. Chem., 2021, 通讯作者
（7） Ultrastretchable, highly transparent, self-adhesive, and 3D-printable ionic hydrogel for multimode tactical sensing, Chemistry of Materials, 2021, 第 6 作者
（8） Gold complexes of bis-indazole-derived N-Heterocyclic carbene: Synthesis, structural characterizations, and catalysis, JOURNAL OF MOLECULAR STRUCTURE, 2021, 通讯作者
（9） Three-Dimensional-Printable Thermo/Photo-Cross-Linked Methacrylated Chitosan-Gelatin Hydrogel Composites for Tissue Engineering, ACS APPLIED MATERIALS & INTERFACES, 2021, 第 4 作者
（10） Reinforced macromolecular micelle-crosslinked hyaluronate gels induced by water/DMSO binary solvent, SOFT MATTER, 2020, 通讯作者
（11） Understanding of Growth Mechanism and Structure of Multilayer Thin Films via Layer-by-Layer Hydrogen Bonded Assembly from Polymer Brushes-Grafted Surface, NANOSCIENCE AND NANOTECHNOLOGY LETTERS, 2020, 通讯作者
（12） Mechano-Responsive, Tough, and Antibacterial Zwitterionic Hydrogels with Controllable Drug Release for Wound Healing Applications, ACS APPLIED MATERIALS & INTERFACES, 2020, 第 7 作者
（13） Stretchable, self-healing and tissue-adhesive zwitterionic hydrogels as strain sensors for wireless monitoring of organ motions, MATERIALS HORIZONS, 2020, 第 3 作者
（14） Biomimetic epidermal sensors assembled from polydopamine-modified reduced graphene oxide/polyvinyl alcohol hydrogels for the real-time monitoring of human motions, JOURNAL OF MATERIALS CHEMISTRY B, 2020, 
（15） Direct 3D Printed Biomimetic Scaffolds Based on Hydrogel Microparticles for Cell Spheroid Growth, ADVANCED FUNCTIONAL MATERIALS, 2020, 第 4 作者
（16） Effect of solvent-matrix interactions on structures and mechanical properties of micelle-crosslinked gels, JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 2019, 第 7 作者
（17） A quinoxalinone-derivated fluorescence sensor with optimized solubility for cysteine detection and biological imaging, DYES AND PIGMENTS, 2019, 通讯作者
（18） Flexible and wearable strain sensors based on tough and self-adhesive ion conducting hydrogels, JOURNAL OF MATERIALS CHEMISTRY B, 2019, 第 5 作者
（19） Development of novel chromeno4,3-cpyrazol-4(2H)-one derivates containing piperazine as inhibitors of PI3K alpha, BIOORGANIC CHEMISTRY, 2019, 第 2 作者
（20） Development of novel chromeno4,3-cpyrazol-4(2H)-one derivates containing piperazine as inhibitors of PI3Kα, BIOORGANIC CHEMISTRY, 2019, 第 2 作者
（21） Tough, Adhesive, Self-Healable, and Transparent Ionically Conductive Zwitterionic Nanocomposite Hydrogels as Skin Strain Sensors, ACS APPLIED MATERIALS & INTERFACES, 2019, 第 3 作者
（22） Synergistic pH and Temperature-Driven Actuation of Poly(NIPAM-co-DMAPMA)/Clay Nanocomposite Hydrogel Bilayers, ACS OMEGA, 2018, 第 5 作者

   

（ 1 ） 基于β-酮酰-ACP缩合酶的多靶点硫内酯霉素结构修饰与抗菌活性研究, 负责人, 国家任务, 2021-01--2023-12
（ 2 ） 新型硫脲-醚甜菜碱两性离子水凝胶的合成、力学性能、自愈性能及抗粘附性研究, 负责人, 地方任务, 2019-01--2021-12
（ 3 ） 骨诱导及抗菌型超高分子量聚乙烯-多孔钛涂层人工关节关键技术研究, 参与, 其他国际合作项目, 2020-01--2021-12
（ 4 ） 基于β-酮酰-ACP缩合酶的新型多靶点抗菌药物开发, 负责人, 地方任务, 2020-09--2023-08