基本信息
陈桂林  男  硕导  中国科学院武汉植物园
email: glchen@wbgcas.cn
address: 湖北省武汉市东湖新技术开发区九峰一路201号
postalCode:

招生信息

   
招生专业
071001-植物学
100800-中药学
100800-中药学
招生方向
植物化学生物学

工作经历

   
工作简历
2019-09~2021-07,中国科学院武汉植物园, 副研究员
2017-07~2019-08,中国科学院武汉植物园, 助理研究员

专利与奖励

   
专利成果
( 1 ) 一种快速筛选抗寄生虫活性化合物的方法, 2022, 第 3 作者, 专利号: 202210000231.7

( 2 ) 一种快速筛选天然产物中拓扑异构酶I抑制剂的方法, 2016, 第 2 作者, 专利号: CN105717250A

出版信息

   
发表论文
(1) Gymnema sylvestre extract ameliorated streptozotocin-induced hyperglycemia in T2DM rats via gut microbiota, Food Frontiers, 2023, 第 1 作者
(2) New Lignanamides with Antioxidant and Anti-Inflammatory Activities Screened Out and Identified from Warburgia ugandensis Combining Affinity Ultrafiltration LC-MS with SOD and XOD Enzymes, ANTIOXIDANTS, 2021, 第 2 作者
(3) Phenolic Compounds from Carissa spinarum Are Characterized by Their Antioxidant, Anti-Inflammatory and Hepatoprotective Activities, ANTIOXIDANTS, 2021, 第 5 作者
(4) Identification of Anti-Inflammatory and Anti-Proliferative Neolignanamides from Warburgia ugandensis Employing Multi-Target Affinity Ultrafiltration and LC-MS, PHARMACEUTICALS, 2021, 第 3 作者
(5) Anti-Inflammatory Properties and Potential Bioactive Components from Moringa oleifera Leaves Revealed by Affinity Ultrafiltration LC−MS and Molecular Docking, ACS Food Science & Technology, 2021, 第 1 作者
(6) Insecticidal Activities Against Odontotermes formosanus and Plutella xylostella and Corresponding Constituents of Tung Meal from Vernicia fordii, INSECTS, 2021, 第 2 作者
(7) Antioxidant and Antiproliferative Potentials of Ficus glumosa and Its Bioactive Polyphenol Metabolites, PHARMACEUTICALS, 2021, 第 6 作者
(8) Hypoglycemic and hypolipidemic effects of Moringa oleifera leaves and their functional chemical constituents, FOOD CHEMISTRY, 2020, 第 1 作者
(9) Antioxidant, Anti-inflammatory Activities and Polyphenol Profile of Rhamnus prinoides, PHARMACEUTICALS, 2020, 第 1 作者
(10) Headspace gas chromatographic method for antimicrobial screening: Minimum inhibitory concentration determination, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 第 3 作者
(11) Screening for natural inhibitors of human topoisomerases from medicinal plants with bio-affinity ultrafiltration and LC-MS, PHYTOCHEMISTRY REVIEWS, 2020, 第 2 作者
(12) 非洲白参的抗氧化活性及其化学成分研究, Antioxidant activities and chemical constituents of roots of Mondia whiteii(Hook.f.)Skeels, 植物科学学报, 2020, 第 4 作者
(13) 响应面法优化飞龙掌血中总生物碱的提取工艺, Optimization of the extraction process of total alkaloids in Toddalia asiatica(L.)Lam.by response surface methodology, 植物科学学报, 2020, 第 2 作者
(14) Antioxidant and Anti-Proliferative Properties of Hagenia abyssinica Roots and Their Potentially Active Components, ANTIOXIDANTS, 2020, 第 2 作者
(15) Recent Advances in Molecular Docking for the Research and Discovery of Potential Marine Drugs, MARINE DRUGS, 2020, 第 1 作者
(16) Antiproliferative and Enzyme Docking Analysis of Engleromycin from Engleromyces goetzei, MOLECULES, 2019, 第 2 作者
(17) In-situ headspace analysis of metabolic carbon dioxide of aerobic bacteria for assessing antimicrobial activity of natural products, JOURNAL OF CHROMATOGRAPHY A, 2019, 第 3 作者
(18) Advances in MS Based Strategies for Probing Ligand-Target Interactions: Focus on Soft Ionization Mass Spectrometric Techniques, FRONTIERSINCHEMISTRY, 2019, 第 1 作者
(19) Comparative and chemometric analysis of correlations between the chemical fingerprints and anti-proliferative activities of ganoderic acids from three Ganoderma species, PHYTOCHEMICAL ANALYSIS, 2019, 第 3 作者
(20) One-Pot Synthesis of Epirubicin-Capped Silver Nanoparticles and Their Anticancer Activity against Hep G2 Cells, PHARMACEUTICS, 2019, 第 2 作者
(21) Antioxidant and Anti-Inflammatory Activities of the Crude Extracts of Moringa oleifera from Kenya and Their Correlations with Flavonoids, ANTIOXIDANTS, 2019, 第 2 作者
(22) Antioxidant and anti-inflammatory properties of flavonoids from lotus plumule, FOOD CHEMISTRY, 2019, 第 1 作者
(23) Research advances in traditional and modern use of Nelumbo nucifera: phytochemicals, health promoting activities and beyond, CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2019, 第 1 作者
(24) Antioxidant and anti-inflammatory properties of flavonoids from lotus plumule, 3RD INTERNATIONAL SYMPOSIUM ON PHYTOCHEMICALS IN MEDICINE AND FOOD (ISPMF), 2019, 第 1 作者
(25) Enrichment and analysis of quaternary alkaloids from Zanthoxylum simulans using weak cation exchange solid-phase extraction coupled with LC-MS, PHYTOCHEMICAL ANALYSIS, 2019, 第 3 作者
(26) Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants, PHYTOCHEMICAL ANALYSIS, 2018, 第 2 作者
(27) Current advances in screening for bioactive components from medicinal plants by affinity ultrafiltration mass spectrometry, PHYTOCHEMICAL ANALYSIS, 2018, 第 1 作者
(28) Screening for anti-proliferative and anti-inflammatory components from Rhamnus davurica Pall. using bio-affinity ultrafiltration with multiple drug targets, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2018, 第 1 作者
(29) Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam., FRONTIERS IN PHARMACOLOGY, 2018, 第 4 作者
(30) Rapid re-evaluation of bioactive saponins from Paris polyphylla using affinity ultrafiltration-LC/MS with multiple drug targets, INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2018, 第 1 作者
(31) Screening for Natural Inhibitors of Topoisomerases I from Rhamnus davurica by Affinity Ultrafiltration and High-Performance Liquid Chromatography-Mass Spectrometry, FRONTIERS IN PLANT SCIENCE, 2017, 第 1 作者
(32) Comparative Analysis of Saponins from Different Phytolaccaceae Species and Their Antiproliferative Activities, MOLECULES, 2017, 第 2 作者
(33) Rapid Screening for alpha-Glucosidase Inhibitors from Gymnema sylvestre by Affinity Ultrafiltration-HPLC-MS, FRONTIERS IN PHARMACOLOGY, 2017, 第 1 作者
(34) Screening for inhibitors of topoisomerase I from Lycoris radiata by combining ultrafiltration with liquid chromatography/mass spectrometry, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2016, 第 1 作者
(35) Analysis of Flavonoids in Rhamnus davurica and Its Antiproliferative Activities, MOLECULES, 2016, 第 1 作者
(36) Mass spectrometry based translational proteomics for biomarker discovery and application in colorectal cancer, PROTEOMICS CLINICAL APPLICATIONS, 2016, 第 2 作者
(37) Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I, SCIENTIFIC REPORTS, 2016, 第 1 作者

科研活动

   
科研项目
( 1 ) 基于药物蛋白质组学与多靶点超滤筛选研究匙羹藤干预餐后高血糖的作用机制与活性物质基础, 负责人, 国家任务, 2020-01--2022-12
( 2 ) 中国科学院青年创新促进会, 负责人, 中国科学院计划, 2020-01--2023-12
( 3 ) 基于多靶点超滤质谱研究中药匙羹藤降糖的活性物质基础与作用机制, 负责人, 地方任务, 2019-09--2021-09
( 4 ) 高荷叶碱荷叶种质资源开发研究, 负责人, 地方任务, 2022-06--2024-06
( 5 ) 非洲传统药用植物资源保护与可持续性利用合作研究, 负责人, 中国科学院计划, 2021-01--2023-12
参与会议
(1)Gymnema sylvestre ameliorates streptozotocin-induced hyperglycemia in T2DM rats via gut microbiota   第六届医药与食品中的植物化学物质国际会议   2022-08-08