基本信息
卜德超  男  硕导  中国科学院计算技术研究所
电子邮件: budechao@ict.ac.cn
通信地址: 科学院南路6号
邮政编码:

招生信息

   
招生专业
081203-计算机应用技术
081202-计算机软件与理论
0812J3-生物信息学
招生方向
医疗多模态人工智能
医学图像处理

教育背景

2011-09--2015-06   中国科学院计算技术研究所   博士
2009-09--2011-06   中国科学院计算技术研究所   硕士
2005-09--2009-07   山东大学   学士

工作经历

   
工作简历
2015-07~现在, 中国科学院计算技术研究所, 任职
社会兼职
2022-02-01-今,Frontiers in Bioengineering and Biotechnology, Review Editor
2021-10-01-2023-12-31,中华中医学会感染病分会, 第六届委员会青年委员
2021-02-01-今,Frontiers in Genetics, Review Editor
2020-12-22-2021-12-31,中国抗癌协会肿瘤标志专业委员会, 肿瘤多学科诊断(MDD)协作组委员

专利与奖励

   
奖励信息
(1) Clarivate2022全球高被引学者, , 国家级, 2022
(2) 浙江省生物信息学会自然科学奖, 一等奖, 省级, 2021
专利成果
[1] 任菲, 罗坚诚, 刘志勇, 刘玉东, 张弘, 卜德超. 基于病理图像的TMB分类方法、系统及TMB分析装置. CN: CN110866893B, 2021-04-06.

出版信息

   
发表论文
(1) Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer, JOURNAL OF ADVANCED RESEARCH, 2022, 第 2 作者
(2) HERB: a high-throughput experiment- and reference-guided database of traditional Chinese medicine, NUCLEIC ACIDS RESEARCH, 2021, 第 7 作者
(3) Imbalance of TGF-beta 1/BMP-7 pathways induced by M2-polarized macrophages promotes hepatocellular carcinoma aggressiveness, MOLECULAR THERAPY, 2021, 第 3 作者
(4) Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity, Single-cell Long Non-coding RNA Landscape of T Cells in Human Cancer Immunity, GENOMICS PROTEOMICS & BIOINFORMATICS, 2021, 第 2 作者
(5) ncFANs v2.0: an integrative platform for functional annotation of non-coding RNAs, NUCLEIC ACIDS RESEARCH, 2021, 第 2 作者
(6) KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis, NUCLEIC ACIDS RESEARCH, 2021, 第 1 作者
(7) NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants, NUCLEIC ACIDS RESEARCH, 2021, 第 7 作者
(8) FangNet: Mining herb hidden knowledge from TCM clinical effective formulas using structure network algorithm, COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 第 1 作者
(9) A high‐quality walnut genome assembly reveals extensive gene expression divergences after whole‐genome duplication, PLANT BIOTECHNOLOGY JOURNAL, 2020, 第 6 作者
(10) 肥厚型心肌病可变剪接图谱分析, Analysis of Alternative Splicing Profile in Hypertrophic Cardiomyopathy, 中国分子心脏病学杂志, 2020, 第 2 作者
(11) SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping, NUCLEIC ACIDS RESEARCH, 2019, 第 5 作者
(12) CircRNAwrap - a flexible pipeline for circRNA identification, transcript prediction, and abundance estimation, FEBS LETTERS, 2019, 第 2 作者
(13) The Transcriptome Landscape of Walnut Interspecies Hybrid (Juglans hindsii x Juglans regia) and Regulation of Cambial Activity in Relation to Grafting, FRONTIERS IN GENETICS, 2019, 第 2 作者
(14) Identification and function annotation of long intervening noncoding RNAs., BRIEFINGS IN BIOINFORMATICS, 2017, 第 2 作者
(15) 哺乳动物长链非编码RNA的进化注释, 中国科学. 生命科学, 2016, 第 1 作者
(16) NONCODE 2016: an informative and valuable data source of long non-coding RNAs, NUCLEIC ACIDS RESEARCH, 2016, 第 8 作者
(17) Phenotype-Genotype Association Analysis of ACTH-Secreting Pituitary Adenoma and Its Molecular Link to Patient Osteoporosis, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 第 4 作者
(18) Evolutionary annotation of conserved long non-coding RNAs in major mammalian species, SCIENCE CHINA-LIFE SCIENCES, 2015, 第 1 作者
(19) 当生物医学遇上大数据, 北大商业评论, 2015, 第 2 作者
(20) NONCODEv4: exploring the world of long non-coding RNA genes, NUCLEIC ACIDS RESEARCH, 2014, 
(21) Downregulation of Insulin-like growth factor binding protein 6 is associated with ACTH-secreting pituitary adenoma growth, PITUITARY, 2014, 第 4 作者
(22) Comprehensive Characterization of 10,571 Mouse Large Intergenic Noncoding RNAs from Whole Transcriptome Sequencing, PLOS ONE, 2013, 第 4 作者
(23) 蛋白质基因组学:运用蛋白质组技术注释基因组, Proteogenomics:Improving Genomes Annotation by Proteomics, PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2013, 第 4 作者
(24) Long non-coding RNAs function annotation: a global prediction method based on bi-colored networks, NUCLEIC ACIDS RESEARCH, 2013, 
(25) Genome-wide identification of cancer-related polyadenylated and non-polyadenylated RNAs in human breast and lung cell lines, SCIENCE CHINA-LIFE SCIENCES, 2013, 
(26) Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts, NUCLEIC ACIDS RESEARCH, 2013, 第 3 作者
(27) Utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts, NUCLEIC ACIDS RESEARCH, 2013, 
(28) 蛋白质基因组学:运用蛋白质组技术注释基因组, Proteogenomics:Improving Genomes Annotation by Proteomics, PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2013, 第 4 作者
(29) 基于转录组测序在人类全基因组内鉴定与癌症相关的polyadenylation和non-polyadenylation RNA, 中国科学. 生命科学, 2013, 第 7 作者
(30) Systematic study of human long intergenic non-coding RNAs and their impact on cancer, SCIENCECHINALIFESCIENCES, 2013, 第 4 作者
(31) Genome-wide identification of cancer-related polyadenylated and non-polyadenylated RNAs in human breast and lung cell lines, SCIENCE CHINA-LIFE SCIENCES, 2013, 
(32) CloudLCA: finding the lowest common ancestor in metagenome analysis using cloud computing, PROTEIN & CELL, 2012, 
(33) NONCODE v3.0: integrative annotation of long noncoding RNAs, NUCLEIC ACIDS RESEARCH, 2012, 
(34) NcFANs: a web server for functional annotation of long non-coding RNAs, NUCLEIC ACIDS RESEARCH, 2011, 
(35) Large-scale prediction of long non-coding RNA functions in a coding–non-coding gene co-expression network, NUCLEIC ACIDS RESEARCH, 2011, 第 9 作者
发表著作
(1) RNA Mapping:De Novo Approach to Classify Protein-Coding and Noncoding Transcripts Based on Sequence Composition, Springer, 2014-06, 第 2 作者

科研活动

   
科研项目
( 1 ) 生物数据智能化管理及解析和检索系统, 负责人, 国家任务, 2021-12--2024-11
( 2 ) 名老中医经验研究与推广应用一体化平台构建, 负责人, 国家任务, 2018-12--2022-12
( 3 ) 基于多模态信息融合的交叉分析算法及智能挖掘技术研发, 负责人, 国家任务, 2022-11--2024-05
( 4 ) mRNA 疫苗核酸序列设计平台 TheraRNA的优化及验证, 负责人, 地方任务, 2023-01--2025-12

指导学生

现指导学生

徐珠峰  硕士研究生  085400-电子信息