基本信息
黄新异  男  博导  中国科学院兰州化学物理研究所
电子邮件: huangxy@licp.cas.cn
通信地址: 甘肃省兰州市天水中路18号
邮政编码: 730000

招生信息

   
招生专业
070302-分析化学
招生方向
分离分析科学
天然药物制备技术

教育背景

2007-09--2010-07   中国科学院研究生院   博士
2002-09--2005-06   兰州理工大学   硕士
1998-09--2002-06   兰州理工大学   本科

工作经历

   
工作简历
2019-08~现在, 中国科学院兰州化学物理研究所, 研究员
2014-01~2014-12,布鲁奈尔大学(Brunel University), 访问学者
2011-12~2019-07,中国科学院兰州化学物理研究所, 副研究员
2008-04~2011-11,中国科学院兰州化学物理研究所, 助理研究员
2007-09~2010-07,中国科学院研究生院, 博士
2005-06~2008-03,中国科学院兰州化学物理研究所, 研实员
2002-09~2005-06,兰州理工大学, 硕士
1998-09~2002-06,兰州理工大学, 本科
社会兼职
2017-04-01-今,甘肃省药学学会药物分析专业委员会, 委员
2016-01-01-2019-12-31,中国科学院青年创新促进会, 会员
2014-03-01-今,中国化学会, 会员

专利与奖励

   
奖励信息
(1) 特色营养健康食品研究开发与产业化, 一等奖, 省级, 2021
(2) 油橄榄副产物综合利用技术开发及产业化, 其他, 2020
(3) 棘豆扶正颗粒抗肿瘤药物临床前研究, 三等奖, 市地级, 2020
(4) 马铃薯绿色高效种植关键技术研究与应用, 三等奖, 省级, 2017
专利成果
( 1 ) 一种油橄榄果中降血脂活性组分的提取方法及降血脂活性组分、降血脂活性组分的评估方法, 2021, 第 3 作者, 专利号: CN113230312A

( 2 ) 一种提取分离枸杞果实中玉米黄质及其棕榈酸酯色素单体的方法, 2021, 第 3 作者, 专利号: CN112142636B

( 3 ) 一种分离枸杞色素单体的方法, 2021, 第 1 作者, 专利号: CN111153843B

( 4 ) 一种油橄榄果中橄榄油的提取方法, 2021, 第 3 作者, 专利号: CN112481019A

( 5 ) 一种样品提取与色谱联用装置, 2020, 第 1 作者, 专利号: CN211785352U

( 6 ) 一种分离制备克级高纯度天然产物的方法, 2020, 第 3 作者, 专利号: CN110922439A

( 7 ) 一种大孔树脂联用制备液相色谱分离高纯度橄榄苦苷的方法, 2020, 第 1 作者, 专利号: CN106967137B

( 8 ) 从油橄榄叶中同步分离纯化橄榄苦苷和羟基酪醇的方法, 2019, 第 3 作者, 专利号: CN109400658A

( 9 ) 一种循环皂化萃取提取茄尼醇的方法, 2018, 第 1 作者, 专利号: CN107663146A

( 10 ) 一种分离高纯度橄榄苦苷的方法, 2017, 第 1 作者, 专利号: CN106967136A

( 11 ) 一种从油橄榄果水中分离制备羟基酪醇的方法, 2017, 第 4 作者, 专利号: CN106883102A

( 12 ) 一种含棘豆的中药复方组合物, 2017, 第 3 作者, 专利号: CN106344658A

( 13 ) 一种列管式连续液-液逆流萃取设备, 2016, 第 1 作者, 专利号: CN205730456U

( 14 ) 一种油橄榄叶中抗糖尿病活性部位的提取方法, 2014, 第 2 作者, 专利号: CN103830332A

( 15 ) 采用大孔树脂吸附提取油橄榄叶抗糖尿病有效部位的方法, 2014, 第 2 作者, 专利号: CN103830333A

( 16 ) 一种逆流色谱法分离苦马豆素的方法, 2013, 第 2 作者, 专利号: CN103073544A

( 17 ) 从油橄榄果渣中提取含有山楂酸和齐墩果酸混合物的方法, 2013, 第 2 作者, 专利号: CN103169771A

( 18 ) 从甜叶菊中制备甜菊糖苷的工艺方法, 2011, 第 2 作者, 专利号: CN102060891A

( 19 ) 从甘肃棘豆中提取总生物碱提取物的制备工艺, 2011, 第 2 作者, 专利号: CN102100725A

( 20 ) 从甘肃棘豆中分离提取苦马豆素的工艺方法, 2010, 第 2 作者, 专利号: CN101177426B

( 21 ) 具有抗癌活性的核桃素及其制备方法, 2010, 第 3 作者, 专利号: CN101824013A

( 22 ) 具有抗癌活性的核桃素及其制备方法和应用, 2009, 第 3 作者, 专利号: CN101456797

( 23 ) 具有抗癌活性的核桃素及其制备方法, 2009, 第 3 作者, 专利号: CN100567285

( 24 ) 一种黄参多糖含片及其生产工艺, 2009, 第 2 作者, 专利号: CN101461524

( 25 ) 一种黄参多糖制备方法, 2009, 第 2 作者, 专利号: CN101463094

( 26 ) 一种当归精油的提取方法, 2008, 第 3 作者, 专利号: CN101176740

出版信息

   
发表论文
(1) Comprehensive separation of a wide variety of compounds from olive leaves by counter-current chromatography with three-phase solvent system, JOURNAL OF SEPARATION SCIENCE, 2022, 通讯作者
(2) The separation regularity of the three-phase solvent system of counter-current chromatography based on polarity parameter modeling, JOURNAL OF CHROMATOGRAPHY A, 2022, 通讯作者
(3) Identification of characteristic flavour compounds and quality analysis in extra virgin olive oil based on HS-GC-IMS, INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 2022, 通讯作者
(4) Role of three-phase solvent system in the counter-current chromatography, JOURNAL OF SEPARATION SCIENCE, 2022, 通讯作者
(5) A model for continuous sample feed and separation with counter-current chromatography based on elution-extrusion mode and its application, JOURNAL OF SEPARATION SCIENCE, 2022, 通讯作者
(6) Recovery and recycling of solvent of counter-current chromatography: The sample of isolation of zeaxanthin in theLycium barbarumL. fruits, JOURNAL OF SEPARATION SCIENCE, 2021, 通讯作者
(7) Development of an effective method based upon second-order overlapping repeated sample injections for isolation of carotenoids from Lycium barbarum L. fruits with elution-extrusion counter-current chromatography, JOURNAL OF CHROMATOGRAPHY A, 2021, 通讯作者
(8) Role of three-phase solvent system in the counter-current chromatography, JOURNAL OF SEPARATION SCIENCE, 2021, 通讯作者
(9) Chemical constituents from the pericarps of Zanthoxylum bungeanum and their chemotaxonomic significance, BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2021, 第 5 作者
(10) Quality Assessment and Classification of Goji Berry by an HPLC-based Analytical Platform Coupled with Multivariate Statistical Analysis, FOOD ANALYTICAL METHODS, 2020, 第 3 作者
(11) Full use of the liquid nature of the stationary phase: The development of elution-extrusion counter current chromatography, JOURNAL OF SEPARATION SCIENCE, 2020, 通讯作者
(12) The applicability of high-speed counter current chromatography to the separation of natural antioxidants, JOURNAL OF CHROMATOGRAPHY A, 2020, 通讯作者
(13) Effective on-line high-speed shear dispersing emulsifier technique coupled with high-performance countercurrent chromatography method for simultaneous extraction and isolation of carotenoids fromLycium barbarumL. fruits, JOURNAL OF SEPARATION SCIENCE, 2020, 通讯作者
(14) 离子液体在高速逆流色谱分离制备天然产物中的研究进展, Advance in the separation and preparation of natural products for ionic liquids by high-speed counter-current chromatography, 天然产物研究与开发, 2020, 第 2 作者
(15) Chiral counter-current chromatography: A survey of its instrument, mechanism, procedure, and applications, CHIRALITY, 2020, 通讯作者
(16) Strategy for the separation of strongly polar antioxidant compounds from Lycium barbarum L. via high-speed counter-current chromatography, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 第 4 作者
(17) 基于高速逆流色谱的大极性海参多肽分离方法研究, Separation study of strong polar polypeptide from sea cucumber by high speed countercurrent chromatography, 天然产物研究与开发, 2019, 第 5 作者
(18) 溶剂系统极性在高速逆流色谱分离油橄榄叶多酚类化合物过程中的影响, The influence of the solvent system polarity for the isolation of polyphenols of Olive leaves by high-speed counter-current chromatography, 天然产物研究与开发, 2019, 第 4 作者
(19) 基于新型溶剂系统筛选的高速逆流色谱分离油橄榄叶中的多酚类化合物, High-speed countercurrent chromatography based on screening of new solvent systems in separation of polyphenols compounds from olive leaves, 北京中医药大学学报, 2019, 第 6 作者
(20) Rapid screening and separating two radical scavengers in Lycium barbarum L. by DPPH-HPLC analysis-combined dual-mode high-speed countercurrent chromatography, SEPARATION SCIENCE AND TECHNOLOGY, 2019, 通讯作者
(21) 芪豆扶正提取物对H22荷瘤小鼠的抗肿瘤作用研究, The Research on Anti-tumor Effects of Qidou Fuzheng Extracts on H22 Tumor-bearing Mice, 西部中医药, 2019, 第 5 作者
(22) Counter-current chromatography melamine-modified column and its separation mechanism, JOURNAL OF SEPARATION SCIENCE, 2019, 通讯作者
(23) Continuous separation of maslinic and oleanolic acids from olive pulp by high-speed countercurrent chromatography with elution-extrusion mode, JOURNAL OF SEPARATION SCIENCE, 2019, 第 1 作者
(24) A review on chiral separation by counter-current chromatography: Development, applications and future outlook, JOURNAL OF CHROMATOGRAPHY A, 2018, 通讯作者
(25) Variable selection and chemometric models for discriminating symptomatic gout based on a metabolic target analysis, JOURNAL OF CHEMOMETRICS, 2018, 第 3 作者
(26) 高速逆流色谱分离制备油橄榄叶中橄榄苦苷, 中成药, 2018, 第 5 作者
(27) 油橄榄叶提取物对2型糖尿病大鼠血糖血脂影响的研究, Study on Effect of Olea europaea L. Leaf Extracts on Blood Sugar and lipid of Type 2 Diabetic Mellitus Rats, 中药药理与临床, 2018, 第 3 作者
(28) Development of overlapping repeated separation of steviol glycosides with counter current chromatography and a comparison with a conventional repeated separation method, JOURNAL OF SEPARATION SCIENCE, 2018, 第 1 作者
(29) The development of biphasic chiral recognition in chiral separation, CHIRALITY, 2018, 第 1 作者
(30) Isolation of high-purity peptide Val-Val-Tyr-Pro from Globin Peptide using MCI gel column combined with high-speed counter-current chromatography, JOURNAL OF SEPARATION SCIENCE, 2018, 第 3 作者
(31) A simple gradient equilibrium method for better separation in countercurrent chromatography, JOURNAL OF SEPARATION SCIENCE, 2018, 通讯作者
(32) 甘肃棘豆的研究进展, 中成药, 2018, 第 3 作者
(33) 施用新型农药控失剂对马铃薯晚疫病的防治效果和产量的影响, Effect of Novel Fungicide Loss-control Agent on Potato Late Blight and Yield, 中国马铃薯, 2017, 第 6 作者
(34) Spiral counter-current chromatography: Design, development, application, and challenges, JOURNAL OF SEPARATION SCIENCE, 2017, 通讯作者
(35) 马铃薯茎叶中茄尼醇提取方法优化与比较, Optimization and Comparison of Extracting Methods of Solanesol in Potato Stem and Leaf, 河南农业科学, 2017, 第 4 作者
(36) Effects of Different Wall-breaking Methods on Extraction of Solanesol from Stems and Leaves of Potato, Effects of Different Wall-breaking Methods on Extraction of Solanesol from Stems and Leaves of Potato, 农业生物技术:英文版, 2017, 第 4 作者
(37) Advances in Technology of Countercurrent Chromatography for Separation of Protein and Peptide, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2016, 第 2 作者
(38) 逆流色谱技术分离蛋白质和多肽的研究进展, 分析化学, 2016, 第 2 作者
(39) DPPH-HPLC-DAD analysis combined HSCCC for screening and identification of radical scavengers in Cynomorium songaricum Rupr, NEW JOURNAL OF CHEMISTRY, 2016, 通讯作者
(40) 新型肥料增效剂对马铃薯肥料减施增效作用研究, Novel Fertilizer Synergist on Saving Fertilizer and ImprovingFertilizer Efficiency, 中国马铃薯, 2016, 第 3 作者
(41) 植物提取物防治马铃薯晚疫病研究进展, Progress in Plant Extracts for Control of Potato Late Blight, 中国马铃薯, 2016, 第 1 作者
(42) An overview of recent progress in elution mode of counter current chromatography, TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2016, 第 1 作者
(43) 逆流色谱新型溶剂体系分离蛋白质和多肽的研究进展, Advances in New Solvent Systems of Countercurrent Chromatography for Separation of Protein and Peptide, 食品工业, 2016, 第 2 作者
(44) 马铃薯茎、叶中茄尼醇皂化研究, Saponification Reaction of Solanesol in Potato Stems and Leaves, 安徽农业科学, 2016, 第 4 作者
(45) An overview of recent progress in elution mode of counter- current chromatography, Trac Trends in Analytical Chemistry, 2016, 
(46) Advances in Technology of Countercurrent Chromatography for Separation of Protein and Peptide, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2016, 第 2 作者
(47) Adsorption mechanism of quercetin, kaempferol and luteolin on surface-modified PTFE films., Adsorption Science & Technology., 2015, 
(48) Adsorption of Quercetin, Kaempferol and Luteolin on Surface-Modified Polytetrafluoroethylene Films, ADSORPTION SCIENCE & TECHNOLOGY, 2015, 第 3 作者
(49) Adsorption of Quercetin, Kaempferol and Luteolin on Surface-Modified Polytetrafluoroethylene Films, ADSORPTION SCIENCE AND TECHNOLOGY, 2015, 第 3 作者
(50) Surface modification of polytetrafluoroethylene column for two-stationary phase separations by counter-current chromatography, JOURNAL OF CHROMATOGRAPHY A, 2015, 第 2 作者
(51) Chiral separation by counter-current chromatography, TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2015, 第 1 作者
(52) Effect of Ionic Liquid on Separation and Purification of Tea Polyphenols Using Counter Current Chromatography, ASIAN JOURNAL OF CHEMISTRY, 2014, 第 2 作者
(53) Use of O-carboxymethyl chitosan in high-speed counter-current chromatography: a novel additive for a biphasic solvent system, NEW JOURNAL OF CHEMISTRY, 2014, 第 3 作者
(54) EFFECTIVE ON-LINE COMBINATION OF HIGH SHEAR TECHNIQUE AND CONTINUOUS SAMPLE INJECTION IN HIGH-PERFORMANCE COUNTER-CURRENT CHROMATOGRAPHY FOR ISOLATION AND PURIFICATION OF POLYPHENOLS IN GREEN TEA, JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2014, 第 3 作者
(55) Efficient method for the screening and identification of anti-diabetic components in the leaves of Olea europaea L., NEW JOURNAL OF CHEMISTRY, 2014, 通讯作者
(56) Effect of Ionic Liquids on Preparative Separation of Flavonoid Compounds in the Extract from Brassica napus L. Pollen using High-Performance Counter-Current Chromatography, SEPARATION SCIENCE AND TECHNOLOGY, 2013, 第 3 作者
(57) 油橄榄果渣中山楂酸和齐墩果酸的提取工艺, Extraction Technology of Maslinic Acid and Oleanolic Acid from Olea europare L. Pomace, 精细化工, 2012, 第 2 作者
(58) 油橄榄叶中总黄酮含量测定方法探讨, Study on the Content Determination of Total Flavonoids in Olea europaea L. Leaves, SPECTROSCOPY AND SPECTRAL ANALYSIS, 2011, 第 4 作者
(59) Study on the Content Determination of Total Flavonoids in Olea europaea L. Leaves, SPECTROSCOPY AND SPECTRAL ANALYSIS, 2011, 第 4 作者
(60) 高速逆流色谱技术分离纯化天然产物中黄酮类化合物的研究进展, Advance of Application of High Speed Counter-current Chromatography in Separation and Purification of Flavonoids, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2011, 第 4 作者
(61) 甜菊糖大孔吸附树脂吸附分离工艺条件的正交设计优化, Orthogonal design optimization of steviosides separation technology by macropores resin, 应用化工, 2011, 第 4 作者
(62) 高速逆流色谱分离纯化天然产物中生物碱类成分的应用进展, Application of high-speed counter-current chromatography in separation and purification for alkaloids in natural products, 中草药, 2011, 第 2 作者
(63) The Separation of Steviosides in the leaves of Stevia rebaudiana Bertoni by Macroporous Resin, JOURNAL OF POLYMER MATERIALS, 2011, 第 3 作者
(64) UV—Vis光谱差减法测定油橄榄叶中橄榄苦苷含量初探, Study on the Content Determination of Oleuropein in Olea europaea L. Leaves by Substraction of UV- Visible Spectroscopy, 分析测试学报, 2011, 第 3 作者
(65) Determination of a novel diarylheptanoid (Juglanin B) from green walnut husks (Juglans regia L.) in rat plasma by high-performance liquid chromatography, BIOMEDICAL CHROMATOGRAPHY, 2010, 第 1 作者
(66) 甜叶菊水提取液的除杂工艺研究, 化学世界, 2010, 第 2 作者
(67) HPLC法测定小鼠血浆中苦马豆素浓度及药动学研究, HPLC determination of swainsonine in mice plasma and its pharmacokinetic study, 药物分析杂志, 2010, 第 2 作者
(68) 大孔吸附树脂预处理-HPLC法测定甘肃棘豆中苦马豆素含量, Pretreatment of Sample Based on Macroporous Adsorptive Resin and Content Determination of Swainsonine in Oxytropis Kansuensis Bunge by HPLC, 分析测试技术与仪器, 2010, 第 2 作者
(69) An improved lc-dad method for simultaneous determination of lutein, beta-carotene and lycopene in tomato and its products, CHROMATOGRAPHIA, 2010, 第 1 作者
(70) Preparative isolation and purification of steviol glycosides from Stevia rebaudiana Bertoni using high-speed counter-current chromatography, SEPARATION AND PURIFICATION TECHNOLOGY, 2010, 第 1 作者
(71) An Improved LC-DAD Method for Simultaneous Determination of Lutein, β-Carotene and Lycopene in Tomato and Its Products, CHROMATPGRAPHIA, 2010, 第 1 作者
(72) 番茄红素软胶囊质量标准研究, Study on quality standard for lycopene soft gels, 食品科技, 2009, 第 2 作者
(73) Simultaneous determination of three diarylheptanoids and an a-tetralone derivative in the green walnut husks (Juglans regia L.) by high-performance liquid chromatography with photodiode array detector., JOURNAL OF CHROMATOGR-APHY A, 2008, 第 4 作者
(74) Simultaneous determination of three diarylheptanoids and an alpha-tetralone derivative in the green walnut husks (Juglans regia L.) by high-performance liquid chromatography with photodiode array detector, JOURNAL OF CHROMATOGRAPHY A, 2008, 第 4 作者
(75) Two new diarylheptanoids from the pericarps of Juglans regia L., CHINESE CHEMICAL LETTERS, 2007, 第 3 作者
(76) Regiolone from the pericarps of Juglans regia L., ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 第 4 作者
(77) 逆流萃取法提取甘肃棘豆中的苦马豆素, Counter-flow Extraction of Swainsonine from Oxytrops kansuensis, 精细化工, 2007, 第 1 作者
(78) A New Flavonoid from Oxytropis kansuensis, CHINESE CHEMICAL LETTERS, 2006, 第 2 作者

科研活动

   
科研项目
( 1 ) 基于CIL@CNTs新型手性选择剂的合成及其在HSCCC手性分离中的应用基础研究, 负责人, 国家任务, 2016-01--2018-12
( 2 ) 医疗机构制剂-芪豆扶正胶囊临床前研究, 负责人, 中国科学院计划, 2015-09--2017-08
( 3 ) 基于手性离子液的泡沫逆流色谱对映体拆分应用基础研究, 负责人, 地方任务, 2015-07--2017-06
( 4 ) 马铃薯茎叶提取茄尼醇技术的开发和示范, 负责人, 地方任务, 2015-01--2017-12
( 5 ) 芪豆扶正胶囊临床前研究, 负责人, 地方任务, 2015-01--2017-12
( 6 ) 中国科学院青年创新促进会会员, 负责人, 中国科学院计划, 2016-01--2019-12
( 7 ) 天然药物新药-扶糖平临床前研究, 负责人, 国家任务, 2017-01--2020-12
( 8 ) 基于手性离子液和泡沫逆流色谱的手性分离新技术研究, 负责人, 国家任务, 2021-01--2024-12
( 9 ) 抗糖尿病天然药物新药-扶糖平临床前研究, 负责人, 地方任务, 2020-11--2022-10
( 10 ) 高品质橄榄油关键技术开发、集成示范与应用, 参与, 地方任务, 2021-10--2024-09
( 11 ) 枸杞多糖改善血糖功能产品创制与应用, 负责人, 地方任务, 2022-11--2024-10
( 12 ) 中国科学院区域发展青年学者, 负责人, 中国科学院计划, 2023-01--2027-12
参与会议
(1)基于洗脱-洗出模式的二阶重叠逆流色谱方法建立及其在枸杞色素分离中的应用   中国化学会第十三届全国生物医药色谱及相关技术学术交流会   2021-05-05
(2)高速逆流色谱在天然药物分离中的应用研究   中国科学院青年创新促进会第二届“百草”论坛   2020-11-22
(3)高速逆流色谱在药物分离中的应用   第十届全国药物分析大会   2020-11-20
(4)逆流色谱Elution-Extrusion模式实现天然产物中目标化合物的连续分离研究   第22届全国色谱学术报告会及仪器展览会   2019-04-21
(5)应用高速逆流色谱技术连续分离 天然产物中活性化合物    中国化学快报系列会议:第二届中国化学快报分析化学前沿论坛   2019-03-23
(6)Separation of strong polar polypeptides by high-speed counter current chromatography   2018-07-30
(7)高速逆流色谱在天然产物分离中的应用   中国中西部地区第六届色谱学术报告会   2018-07-28
(8)逆流色谱在中药化学成分分离中的应用   第十二届生物医药色谱及相关技术学术交流会   黄新异   2018-04-16
(9)Overlapping repeated separation by high-speed counter-current chromatography   黄新异   2017-11-10
(10)HSCCC对甜菊糖苷连续分离模式比较   第21届全国色谱学术报告会及仪器展览会   2017-05-19
(11)Separation of active compounds in traditional Chinese medicine with high-speed counter current chromatography   2017-05-11
(12)应用DPPH-HPLC-HSCCC联用快速分离复杂植物提取物中的天然抗氧化活性物质   2016全国生命分析化学学术大会   2016-12-17
(13)高速逆流色谱技术在天然产物分离中的应用   第十一届全国生物医药色谱及相关技术学术交流会   2016-04-26
(14)逆流色谱色谱技术研究进展   中国中西部地区第五届色谱学术报告会   2016-04-22
(15)Counter-Current Chromatography: A Unique Liquid-Liquid Chromatographic Technology   2015-11-07
(16)高速逆流色谱分离化合物新策略   第二十届全国色谱学术报告会及仪器展览会   2015-04-19