基本信息
郝立凯  男  博导  中国科学院地球化学研究所
email: haolikai@mail.gyig.ac.cn
address: 贵阳林城西路99号
postalCode: 550081

招生信息

   
招生专业
070902-地球化学
0709Z1-地球生物学
招生方向
重金属微生物地球化学
环境分析显微镜技术

教育背景

2011-05--2015-09   德国图宾根大学   地质学博士-环境分析显微镜技术
2004-08--2007-06   山东大学   微生物学硕士
2000-09--2004-06   河北科技大学   生物技术学士

工作经历

   
工作简历
2016-10~现在, 中国科学院地球化学研究所, 研究员
2011-05~2015-09,德国图宾根大学, 地质学博士-环境分析显微镜技术
2011-04~2016-09,德国图宾根大学, 研究助理
2010-03~2010-06,大洋协会 大洋一号, 科考队员
2009-01~2009-04,德国马普海洋微生物所, 访问学者
2009-01~2009-04,丹麦哥本哈根大学, 访问学者
2008-05~2008-08,大洋协会 大洋一号, 科考队员
2007-07~2010-12,厦门大学, 高级显微镜工程师
2004-08~2007-06,山东大学, 微生物学硕士
2000-09~2004-06,河北科技大学, 生物技术学士
社会兼职
2017-02-20-今,中国矿物岩石地球化学学会会员,
2015-10-18-今,中国旅德学者化学化工学会会员,
2012-05-11-今,中国化学会会员,
2012-02-21-今,欧洲地球化学学会会员,

专利与奖励

   
奖励信息
(1) 贵州省省管专家, 一等奖, 省级, 2021
(2) 贵阳生态环境专家, 一等奖, 市地级, 2021
(3) 2014年度国家优秀自费留学生奖学金, 部委级, 2014
专利成果
( 1 ) 可调节采样深度的水体连续采样装置, 2020, 第 3 作者, 专利号: CN211042838U

出版信息

   
发表论文
(1) Coal-source acid mine drainage reduced the soil multidrug-dominated antibiotic resistome but increased the heavy metal(loid) resistome and energy production-related metabolism, SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 通讯作者
(2) Metagenomic analysis characterizes resistomes of an acidic, multimetal(loid)-enriched coal source mine drainage treatment system, JOURNAL OF HAZARDOUS MATERIALS, 2023, 通讯作者
(3) Effect and mechanism of simultaneous cadmium-tetracycline removal by a self-assembled microbial-photocatalytic coupling system, JOURNAL OF HAZARDOUS MATERIALS, 2023, 第 9 作者
(4) Glutathione assisting the waste tobacco leaf to synthesize versatile biomass-based carbon dots for simultaneous detection and efficient removal of mercury ions, JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2022, 通讯作者
(5) Effect of Environmental pH on Mineralization of Anaerobic Iron-Oxidizing Bacteria, FRONTIERS IN MICROBIOLOGY, 2022, 通讯作者
(6) 酸性矿山废水微生物组时空演变特征及微生物-矿物互作机制, Spatio-temporal Evolution Characteristics of Microbiome in Acid Mine Drainage and Microbial-mineral Interaction Mechanism, 生态环境学报, 2022, 第 2 作者
(7) High-Efficiency Utilization of Waste Tobacco Stems to Synthesize Novel Biomass-Based Carbon Dots for Precise Detection of Tetracycline Antibiotic Residues, NANOMATERIALS, 2022, 通讯作者
(8) Rhizosphere Microbial Communities and Geochemical Constraining Mechanism of Antimony Mine Waste-Adapted Plants in Southwestern China, MICROORGANISMS, 2022, 通讯作者
(9) Integrated chamber-free microbial fuel cell for wastewater purification and bioenergy generation, CHEMICAL ENGINEERING JOURNAL, 2022, 其他(合作组作者)
(10) The substrate-dependent regulatory effects of the AfeI/R system in Acidithiobacillus ferrooxidans reveals the novel regulation strategy of quorum sensing in acidophiles, ENVIRONMENTAL MICROBIOLOGY, 2021, 第 3 作者
(11) Secondary Sulfate Minerals from Pyrite Oxidation in Lanmuchang Hg-Tl Deposit, Southwest Guizhou Province, China: Geochemistry and Environmental Significance, BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2021, 第 3 作者
(12) 环境pH对微生物生物膜吸附重金属的影响研究进展, Research Progress of the Effect of pH on the Adsorption of Heavy Metals by Microbial Biofilms, 地球与环境, 2021, 第 4 作者
(13) 激光扫描共聚焦荧光显微镜技术及其在地球生物学中的应用, Confocal Laser Scanning Microscopy and its Application in Geobiology, 矿物岩石地球化学通报, 2020, 第 1 作者
(14) Biological Fe(II) and As(III) oxidation immobilizes arsenic in micro-oxic environments, GEOCHIMICA ET COSMOCHIMICA ACTA, 2019, 第 3 作者
(15) 铁还原细菌Shewanella oneidensis MR-4诱导水合氧化铁形成蓝铁矿的过程, Ferrihydrite reduction and vivianite biomineralization mediated by iron reducing bacterium Shewanella oneidensis MR-4, 微生物学报, 2018, 第 6 作者
(16) 印度洋深海沉积物可培养放线菌多样性及抗革兰阴性菌活性物质研究, Diversity of culturable actinomycetes from the Indian Ocean deep-sea sediment and the identification of the antibacterial metabolites against Gram-negative bacteria, 中国抗生素杂志, 2018, 第 3 作者
(17) Aqueous Fe(II)-Induced Phase Transformation of Ferrihydrite Coupled Adsorption/Immobilization of Rare Earth Elements, MINERALS, 2018, 第 10 作者
(18) Iron Isotope Fractionation during Fe(II) Oxidation Mediated by the Oxygen-Producing Marine Cyanobacterium Synechococcus PCC 7002, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 
(19) Submicron-Scale Heterogeneities in Nickel Sorption of Various Cell-Mineral Aggregates Formed by Fe(II)-Oxidizing Bacteria, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 第 3 作者
(20) Binding of heavy metal ions in aggregates of microbial cells, EPS and biogenic iron minerals measured in-situ using metal- and glycoconjugates-specific fluorophores, GEOCHIMICA ET COSMOCHIMICA ACTA, 2016, 通讯作者
(21) A novel approach to study the structure-property relationships and applications in living systems of modular Cu 2+ fluorescent probes, SCIENTIFIC REPORTS, 2016, 第 3 作者
(22) Novel Fluorescein-Based Fluorescent Probe for Detecting H2S and Its Real Applications in Blood Plasma and Biological Imaging, ANALYTICAL CHEMISTRY, 2016, 第 5 作者
(23) ScatterJ: An ImageJ plugin for the evaluation of analytical microscopy datasets, JOURNAL OF MICROSCOPY, 2016, 
(24) Solvent-dependent turn-on probe for dual monitoring of Ag+ and Zn2+ in living biological samples, ANALYTICA CHIMICA ACTA, 2015, 第 4 作者
(25) Physiology, Fe(II) oxidation, and Fe mineral formation by a marine planktonic cyanobacterium grown under ferruginous conditions, FRONTIERS IN EARTH SCIENCE, 2015, 第 3 作者
(26) Visualizing tributyltin (TBT) in bacterial aggregates by specific rhodamine-based fluorescent probes, ANALYTICA CHIMICA ACTA, 2015, 第 2 作者
(27) Synchrotron-Based Chemical Nano-Tomography of Microbial Cell-Mineral Aggregates in their Natural, Hydrated State, MICROSCOPY AND MICROANALYSIS, 2014, 第 3 作者
(28) 3-D analysis of bacterial cell-(iron)mineral aggregates formed during Fe(II) oxidation by the nitrate-reducing Acidovorax sp. strain BoFeN1 using complementary microscopy tomography approaches, GEOBIOLOGY, 2014, 
(29) Characterization of the physiology and cell-mineral interactions of the marine anoxygenic phototrophic Fe(II) oxidizer Rhodovulum iodosum - implications for Precambrian Fe(II) oxidation, FEMS MICROBIOLOGY ECOLOGY, 2014, 第 3 作者
(30) Six-membered spirocycle opening triggered fluorescent probe for visualizing Hg2+ in living cells and bacteria-EPS-mineral aggregates, Organic Letters, 2013, 第 1 作者
(31) Two novel fluorescein-based fluorescent sensors for hypochlorite and its real applications in tap water and biological imaging, Sensors and Actuators B: Chemical, 2013, 第 1 作者
(32) Mapping of Heavy Metal Ion Sorption to Cell-Extracellular Polymeric Substance-Mineral Aggregates by Using Metal-Selective Fluorescent Probes and Confocal Laser Scanning Microscopy, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2013, 通讯作者
(33) Detection and validation of a small broad-host-range plasmid pBBR1MCS-2 for use in genetic manipulation of the extremely acidophilic Acidithiobacillus sp., JOURNAL OF MICROBIOLOGICAL METHODS, 2012, 第 1 作者
(34) Mamefiella alba gen. nov., sp nov., a marine bacterium of the Roseobacter clade in the order Rhodobacterales, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2010, 第 6 作者
(35) Stakelama pacifica gen. nov., sp nov., a new member of the family Sphingomonadaceae isolated from the Pacific Ocean, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2010, 第 5 作者

科研活动

   
科研项目
( 1 ) 一万五千年青藏高原兹格塘错湖泊沉积物微生物组结构和 功能研究, 负责人, 研究所自主部署, 2018-02--2019-01
( 2 ) 高级光学纳米-超高分辨率-激光扫描共聚焦系统研究细菌代谢途径空间定位及基于同位素示踪技术的代谢通量平衡分析, 负责人, 地方任务, 2018-01--2018-12
( 3 ) 典型多金属采选场地及周边土壤污染物源—汇关系及防治技术原理, 负责人, 国家任务, 2018-12--2022-11
( 4 ) 重金属微生物地球化学微观机制, 负责人, 中国科学院计划, 2017-01--2022-12
( 5 ) 微生物铁循环对原位微观重金属吸附的控制机制, 负责人, 国家任务, 2019-01--2022-12
( 6 ) 印度洋靶区多金属硫化物资源综合评价与勘探区块圈定--矿物原位立体微观成像分析研究, 负责人, 其他国际合作项目, 2019-01--2020-12
( 7 ) 贵州典型矿区采选场地土壤酸化原理防治技术, 负责人, 地方任务, 2022-10--2025-10