基本信息
胡葭  女  硕导  中国科学院武汉病毒研究所
电子邮件: hujia@wh.iov.cn
通信地址: 中科院武汉病毒研究所小洪山中区44号
邮政编码:

招生信息

   
招生专业
071005-微生物学
招生方向
1. 病原微生物致病机制,2. 新发/再发病毒细胞过程调控

教育背景

2009-08--2013-08   美国怀俄明大学   哲学博士
2006-09--2009-06   华中农业大学   农学硕士
2002-09--2006-06   华中农业大学   理学学士

工作经历

   
工作简历
2015-09~现在, 中国科学院武汉病毒研究所, 副研究员
2013-10~2015-05,美国德州大学医学院加尔维斯顿分校, 博后
2009-08~2013-08,美国怀俄明大学, 哲学博士
2006-09~2009-06,华中农业大学, 农学硕士
2002-09~2006-06,华中农业大学, 理学学士

出版信息

   
发表论文
(1) Cis-regulatory decoy disrupts autorepression:a potential escape-resistant anti-viral therapy, Cis-regulatory decoy disrupts autorepression: a potential escape-resistant anti-viral therapy, SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 第 1 作者
(2) Phosphorylation of the Autographa californica multiple nucleopolyhedrovirus polyhedron envelope protein plays an important role in the formation of the occlusion body envelope, JOURNAL OF GENERAL VIROLOGY, 2022, 通讯作者
(3) Genomic analysis of two Chinese isolates of hyphantria cunea nucleopolyhedrovirus reveals a novel species of alphabaculovirus that infects hyphantria cunea drury (lepidoptera: arctiidae), BMC Genomics, 2022, 第 5 作者
(4) Heat shock protein 70, glutamate dehydrogenase, and angiotensin-converting enzyme of Bombyx mori mediate the cell attachment of Cypovirus 1, JOURNAL OF GENERAL VIROLOGY, 2021, 通讯作者
(5) 杆状病毒新的分类地位和书写方式, New Taxonomic Status and Name Writing of the Baculoviruses, 中国生物防治学报, 2021, 第 2 作者
(6) Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids, Autographa Californica Multiple Nucleopolyhedrovirus orf13 Is Required for Efficient Nuclear Egress of Nucleocapsids, VIROLOGICA SINICA, 2021, 通讯作者
(7) On the Calculation of TCID_(50) for Quantitation of Virus Infectivity, On the Calculation of TCID50 for Quantitation of Virus Infectivity, VIROLOGICA SINICA, 2021, 第 3 作者
(8) A Conserved Phenylalanine Residue of Autographa Californica Multiple Nucleopolyhedrovirus AC75 Protein Is Required for Occlusion Body Formation, FRONTIERS IN MICROBIOLOGY, 2021, 通讯作者
(9) Molecular and Biological Characterization of Spodoptera frugiperda Multiple Nucleopolyhedrovirus Field Isolate and Genotypes from China, INSECTS, 2020, 第 4 作者
(10) Displaying enhancing factors on the surface of occlusion bodies improves the insecticidal efficacy of a baculovirus, PEST MANAGEMENT SCIENCE, 2020, 第 5 作者
(11) Increased Excess Intracellular Cyclic di-AMP Levels Impair Growth and Virulence of Bacillus anthracis, JOURNAL OF BACTERIOLOGY, 2020, 第 1 作者
(12) Distribution of airborne SARS-CoV-2 and possible aerosol transmission in Wuhan hospitals, China, Distribution of Airborne SARS-CoV-2 and possible aerosol transmission in Wuhan hospitals, China, NATIONAL SCIENCE REVIEW, 2020, 第 1 作者
(13) NSP2 forms viroplasms during Dendrolimus punctatus cypovirus infection, VIROLOGY, 2019, 第 5 作者
(14) A Reverse Genetics System for Cypovirus Based on a Bacmid Expressing T7 RNA Polymerase, VIRUSES-BASEL, 2019, 第 7 作者
(15) 亚洲玉米螟核型多角体病毒分离株鉴定及其对草地贪夜蛾的室内毒力测定, Identification of an Isolate of Ostrinia furnacalis Nucleopolyhedrovirus and Its Bioactivity against Spodoptera frugiperda Larvae, 中国生物防治学报, 2019, 第 5 作者
(16) Dissecting the Cell Entry Pathway of Baculovirus by Single-Particle Tracking and Quantitative Electron Microscopic Analysis, JOURNAL OF VIROLOGY, 2019, 第 3 作者
(17) Displaying enhancing factors on the surface of occlusion bodies improves the insecticidal efficacy of a baculovirus., Pest Management Science, 2019, 第 5 作者
(18) Autographa californica multiple nucleopolyhedrovirus enters host cells via clathrin-mediated endocytosis and direct fusion with the plasma membrane, VIRUSES-BASEL, 2018, 第 4 作者
(19) Improving Baculovirus Infectivity by Efficiently Embedding Enhancing Factors into Occlusion Bodies, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2017, 第 5 作者
(20) Finding Regulators Associated with the Expression of the Long Polar Fimbriae in Enteropathogenic Escherichia coli, JOURNAL OF BACTERIOLOGY, 2015, 第 1 作者
(21) Defects in Polynucleotide phosphorylase impairs virulence in Escherichia coli O157:H7, FRONTIERS IN MICROBIOLOGY, 2015, 
(22) Enteropathogenic E. coli: foe or innocent bystander?, Clinical microbiology and infection, 2015, 第 1 作者
(23) Recent advances in adherence and invasion of pathogenic Escherichia coli, CURRENT OPINION IN INFECTIOUS DISEASES, 2014, 第 2 作者
(24) c-di-GMP signaling regulates E. coli O157:H7 adhesion to colonic epithelium, VETERINARY MICROBIOLOGY, 2013, 第 1 作者
(25) Polynucleotide phosphorylase is required for E. coli O157: H7 growth at low temperatures., Foodborne pathogen and disease, 2013, 第 1 作者

科研活动

   
科研项目
( 1 ) c-di-AMP信号通路在炭疽杆菌致病机制中的功能研究, 负责人, 国家任务, 2017-01--2019-12
( 2 ) 基于杆状病毒的夜蛾科和其它鳞翅目害虫生物防治技术的开发, 负责人, 国家任务, 2020-01--2021-12
( 3 ) 格力猎手空气净化器抗新型冠状病毒(SARA-CoV-2)的有效性研究, 负责人, 境内委托项目, 2020-11--2022-12
( 4 ) 技术检测(薄膜对甲型流感病毒的杀灭试验), 负责人, 境内委托项目, 2020-10--2022-10
( 5 ) 2019-nCoV病毒的环境影响因素及风险防控策略, 参与, 国家任务, 2020-02--2021-02
( 6 ) 空气和固体表面传播新型冠状病毒的机制研究, 参与, 国家任务, 2020-04--2020-12