071009-细胞生物学
071011-生物物理学
071001-植物学

光合作用膜蛋白结构与功能
光合作用调控机理

2002-09--2005-07   中国科学院植物研究所   理学博士学位
1998-09--2001-09   山西大学分子科学研究所   理学硕士学位
1994-09--1998-07   山西大学生命科学系   理学学士学位

   

2021-05~现在, 中国科学院植物研究所, 研究员
2014-03~2021-05,中国科学院植物研究所, 副研究员
2012-02~2014-03,美国劳伦斯伯克利国家实验室物理科学部, 博士后
2010-01~2012-01,瑞典于墨奥(Umea)大学化学生物学中心, 博士后
2008-06~2009-12,中国科学院植物研究所, 助理研究员
2006-06~2008-06,瑞典乌普萨拉(Uppsala)大学光化学与分子科学系, 博士后
2005-07~2006-06,中国科学院植物研究所, 助理研究员
2001-07~2002-09,山西大学分子科学研究所, 助理教授

   

（1） 中国科学十大进展, 国家级, 2019

   

[1] Song Zhang, Kailu Tang, Qiujing Yan, Xingyue Li, Liangliang Shen, Wenda Wang, Yi-Kun He, Tingyun Kuang, Guangye Han, Jian-Ren Shen, Xing Zhang. Structural insights into a unique PSI–LHCI–LHCII–Lhcb9 supercomplex from moss Physcomitrium patens. Nature Plants[J]. 2023, 9: 832-846, [2] Han, Guangye, Chernev, Petko, Styring, Stenbjorn, Messinger, Johannes, Mamedov, Fikret. Molecular basis for turnover inefficiencies (misses) during water oxidation in photosystem II. CHEMICAL SCIENCE[J]. 2022, 13(29): 8667-8678, http://dx.doi.org/10.1039/d2sc00854h.
[3] Liangliang Shen, Kailu Tang, Wenda Wang, Chen Wang, Hangjun Wu, Zhiyuan Mao, Shaoya An, Shenghai Chang, Tingyun Kuang, Jian-Ren Shen, Guangye Han, Xing Zhang. Architecture of the chloroplast PSI-NDH supercomplex in Hordeum vulgare.. Nature[J]. 2022, 601: 649-654, [4] Zihui Huang, Liangliang Shen, Wenda Wang, Zhiyuan Mao, Xiaohan Yi, Tingyun Kuang, JianRen Shen, Xing Zhang, Guangye Han. Structure of photosystem I-LHCI-LHCII from the green alga Chlamydomonas reinhardtii in State 2. NATURE COMMUNICATIONS[J]. 2021, 12(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7889890/.
[5] Yan, Qiujing, Zhao, Liang, Wang, Wenda, Pi, Xiong, Han, Guangye, Wang, Jie, Cheng, Lingpeng, He, YiKun, Kuang, Tingyun, Qin, Xiaochun, Sui, SenFang, Shen, JianRen. Antenna arrangement and energy-transfer pathways of PSI-LHCI from the moss Physcomitrella patens. CELL DISCOVERY[J]. 2021, 7(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000618354400001.
[6] Huang, Guoqiang, Xiao, Yanan, Pi, Xiong, Zhao, Liang, Zhu, Qingjun, Wang, Wenda, Kuang, Tingyun, Han, Guangye, Sui, SenFang, Shen, JianRen. Structural insights into a dimeric Psb27-photosystem II complex from a cyanobacterium Thermosynechococcus vulcanus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2021, 118(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000615345200035.
[7] Zhu, Qingjun, Yang, Yanyan, Xiao, Yanan, Wang, Wenda, Kuang, Tingyun, Shen, JianRen, Han, Guangye. Function of PsbO-Asp158 in photosystem II: effects of mutation of this residue on the binding of PsbO and function of PSII in Thermosynechococcus vulcanus. PHOTOSYNTHESIS RESEARCH[J]. 2020, 146(1-3): 29-40, https://www.webofscience.com/wos/woscc/full-record/WOS:000518147700001.
[8] 王文达, 韩广业, 匡廷云, 沈建仁. 硅藻和绿藻：光合作用的蛋白体不再神秘. 前沿科学[J]. 2020, 14(1): 14-18, http://lib.cqvip.com/Qikan/Article/Detail?id=7101503834.
[9] Chang, Lijing, Tian, Lirong, Ma, Fei, Mao, Zhiyuan, Liu, Xiaochi, Han, Guangye, Wang, Wenda, Yang, Yanyan, Kuang, Tingyun, Pan, Jie, Shen, JianRen. Regulation of photosystem I-light-harvesting complex I from a red algaCyanidioschyzon merolaein response to light intensities. PHOTOSYNTHESIS RESEARCH[J]. 2020, 146(1-3): 287-297, http://dx.doi.org/10.1007/s11120-020-00778-z.
[10] Chen, JingHua, Wu, Hangjun, Xu, Caihuang, Liu, XiaoChi, Huang, Zihui, Chang, Shenghai, Wang, Wenda, Han, Guangye, Kuang, Tingyun, Shen, JianRen, Zhang, Xing. Architecture of the photosynthetic complex from a green sulfur bacterium. SCIENCE[J]. 2020, 370(6519): 931-+, http://dx.doi.org/10.1126/science.abb6350.
[11] Taguchi, Shota, Shen, Liangliang, Han, Guangye, Umena, Yasufumi, Shen, JianRen, Noguchi, Takumi, Mino, Hiroyuki. Formation of the High-Spin S-2 State Related to the Extrinsic Proteins in the Oxygen Evolving Complex of Photosystem II. JOURNAL OF PHYSICAL CHEMISTRY LETTERS[J]. 2020, 11(20): 8908-8913, http://dx.doi.org/10.1021/acs.jpclett.0c02411.
[12] Xiao, Yanan, Zhu, Qingjun, Yang, Yanyan, Wang, Wenda, Kuang, Tingyun, Shen, JianRen, Han, Guangye. Role of PsbV-Tyr137 in photosystem II studied by site-directed mutagenesis in the thermophilic cyanobacterium Thermosynechococcus vulcanus. PHOTOSYNTHESIS RESEARCH[J]. 2020, 146(1-3): 41-54, https://www.webofscience.com/wos/woscc/full-record/WOS:000529115500001.
[13] Caizhe Xu, Xiong Pi, Yawen Huang, Guangye Han, Xiaobo Chen, Xiaochun Qin, Guoqiang Huang, Songhao Zhao, Yanyan Yang, Tingyun Kuang, Wenda Wang, SenFang Sui, JianRen Shen. Structural basis for energy transfer in a huge diatom PSI-FCPI supercomplex. NATURE COMMUNICATIONS[J]. 2020, 5081-, http://dx.doi.org/10.1038/s41467-020-18867-x.
[14] Sipka, Gabor, Mueller, Pavel, Brettel, Klaus, Magyar, Melinda, Kovacs, Laszlo, Zhu, Qingjun, Xiao, Yanan, Han, Guangye, Lambrev, Petar H, Shen, JianRen, Garab, Gyozo. Redox transients of P680 associated with the incremental chlorophyll-a fluorescence yield rises elicited by a series of saturating flashes in diuron-treated photosystem II core complex of Thermosynechococcus vulcanus. PHYSIOLOGIA PLANTARUM[J]. 2019, 166(1): 22-32, http://dx.doi.org/10.1111/ppl.12945.
[15] Pi, Xiong, Zhao, Songhao, Wang, Wenda, Liu, Desheng, Xu, Caizhe, Han, Guangye, Kuang, Tingyun, Sui, SenFang, Shen, JianRen. The pigment-protein network of a diatom photosystem II-light-harvesting antenna supercomplex. SCIENCE[J]. 2019, 365(6452): 463-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000485768400038.
[16] Shen, Liangliang, Huang, Zihui, Chang, Shenghai, Wang, Wenda, Wang, Jingfen, Kuang, Tingyun, Han, Guangye, Shen, JianRen, Zhang, Xing. Structure of a C2S2M2N2 type PSII-LHCII supercomplex from the green alga Chlamydomonas reinhardtii. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2019, 116(42): 21246-21255, https://www.webofscience.com/wos/woscc/full-record/WOS:000490183000064.
[17] 李真, 祁育, 王旺银, 李登, 李政, 肖亚男, 韩广业, 沈建仁, 李灿. 光系统Ⅱ杂化Z型水分解体系中产氢助催化剂上逆反应的抑制. 催化学报[J]. 2019, 40(4): 486-494, http://lib.cqvip.com/Qikan/Article/Detail?id=7001384952.
[18] Wang, Wenda, Yu, LongJiang, Xu, Caizhe, Tomizaki, Takashi, Zhao, Songhao, Umena, Yasufumi, Chen, Xiaobo, Qin, Xiaochun, Xin, Yueyong, Suga, Michihiro, Han, Guangye, Kuang, Tingyun, Shen, JianRen. Structural basis for blue-green light harvesting and energy dissipation in diatoms. SCIENCE[J]. 2019, 363(6427): eaav0365-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000458114200039.
[19] Chen, Jun, Chen, Jinfan, Liu, Ying, Zheng, Yang, Zhu, Qingjun, Han, Guangye, Shen, JianRen. Proton-Coupled Electron Transfer of Plastoquinone Redox Reactions in Photosystem II: A Pump-Probe Ultraviolet Resonance Raman Study. JOURNAL OF PHYSICAL CHEMISTRY LETTERS[J]. 2019, 10(12): 3240-3247, https://www.webofscience.com/wos/woscc/full-record/WOS:000472804700008.
[20] Li, Zhen, Qi, Yu, Wang, Wangyin, Li, Deng, Li, Zheng, Xiao, Yanan, Han, Guangye, Shen, JianRen, Li, Can. Blocking backward reaction on hydrogen evolution cocatalyst in a photosystem II hybrid Z-scheme water splitting system. CHINESE JOURNAL OF CATALYSIS[J]. 2019, 40(4): 486-494, http://cas-ir.dicp.ac.cn/handle/321008/165620.
[21] Giovagnetti, Vasco, Han, Guangye, Ware, Maxwell A, Ungerer, Petra, Qin, Xiaochun, Wang, WenDa, Kuang, Tingyun, Shen, JianRen, Ruban, Alexander V. A siphonous morphology affects light-harvesting modulation in the intertidal green macroalga Bryopsis corticulans (Ulvophyceae). PLANTA[J]. 2018, 247(6): 1293-1306, http://dx.doi.org/10.1007/s00425-018-2854-5.
[22] Melinda Magyar, Gbor Sipka, Lszl Kovcs, Bettina Ughy, Qingjun Zhu, Guangye Han, Vladimr punda, Petar H Lambrev, JianRen Shen, Gyz Garab. Rate-limiting steps in the dark-to-light transition of Photosystem II - revealed by chlorophyll-a fluorescence induction. SCIENTIFIC REPORTS[J]. 2018, 8(1): https://doaj.org/article/a8cd09bca7e94f0295c45c3ff6448098.
[23] Tian, Lirong, Liu, Zheyi, Wang, Fangjun, Shen, Liangliang, Chen, Jinghua, Chang, Lijing, Zhao, Songhao, Han, Guangye, Wang, Wenda, Kuang, Tingyun, Qin, Xiaochun, Shen, JianRen. Isolation and characterization of PSI-LHCI super-complex and their sub-complexes from a red alga Cyanidioschyzon merolae. PHOTOSYNTHESIS RESEARCH[J]. 2017, 133(1-3): 201-214, http://ir.ibcas.ac.cn/handle/2S10CLM1/15352.
[24] Zhou, Ye, Wu, Yue, Yao, Mingdong, Liu, Zheyi, Chen, Jin, Chen, Jun, Tian, Lirong, Han, Guangye, Shen, JianRen, Wang, Fangjun. Probing the Lysine Proximal Microenvironments within Membrane Protein Complexes by Active Dimethyl Labeling and Mass Spectrometry. ANALYTICAL CHEMISTRY[J]. 2016, 88(24): 12060-12065, http://cas-ir.dicp.ac.cn/handle/321008/151819.
[25] Wang, Wangyin, Wang, Hong, Zhu, Qingjun, Qin, Wei, Han, Guangye, Shen, JianRen, Zong, Xu, Li, Can. Spatially Separated Photosystem II and a Silicon Photoelectrochemical Cell for Overall Water Splitting: A Natural-Artificial Photosynthetic Hybrid. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2016, 55(32): 9229-9233, http://www.corc.org.cn/handle/1471x/2376206.
[26] Chatterjee, Ruchira, Han, Guangye, Kern, Jan, Gul, Sheraz, Fuller, Franklin D, Garachtchenko, Anna, Young, Iris D, Weng, TsuChien, Nordlund, Dennis, AlonsoMori, Roberto, Bergmann, Uwe, Sokaras, Dimosthenis, Hatakeyama, Makoto, Yachandra, Vittal K, Yano, Junko. Structural changes correlated with magnetic spin state isomorphism in the S-2 state of the Mn4CaO5 cluster in the oxygen-evolving complex of photosystem II. CHEMICAL SCIENCE[J]. 2016, 7(8): 5236-5248, https://www.webofscience.com/wos/woscc/full-record/WOS:000380893900054.
[27] Ago, Hideo, Adachi, Hideyuki, Umena, Yasufumi, Tashiro, Takayoshi, Kawakami, Keisuke, Kamiya, Nobuo, Tian, Lirong, Han, Guangye, Kuang, Tingyun, Liu, Zheyi, Wang, Fangjun, Zou, Hanfa, Enami, Isao, Miyano, Masashi, Shen, JianRen. Novel Features of Eukaryotic Photosystem II Revealed by Its Crystal Structure Analysis from a Red Alga. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2016, 291(11): 5676-5687, http://dx.doi.org/10.1074/jbc.M115.711689.
[28] Wang, Wangyin, Wang, Zhiliang, Zhu, Qingjun, Han, Guangye, Ding, Chunmei, Chen, Jun, Shen, JianRen, Li, Can. Direct electron transfer from photosystem II to hematite in a hybrid photoelectrochemical cell. CHEMICAL COMMUNICATIONS[J]. 2015, 51(95): 16952-16955, http://cas-ir.dicp.ac.cn/handle/321008/148217.
[29] 韩广业. Hydration of the oxygen-evolving complex of Photosystem II probed in the dark-stable S1 state by proton NMR dispersion profiles.. Phys. Chem. Chem. Phys.. 2014, [30] Han Guangye, Li Shuqin, Kuang Tingyun. Photoassembly of Manganese Cluster of Photosynthetic Oxygen-Evolving Complex. PROGRESS IN CHEMISTRY[J]. 2010, 22(8): 1556-1565, https://www.webofscience.com/wos/woscc/full-record/WOS:000281270600006.
[31] 韩广业, 李淑芹, 匡廷云. 光合放氧复合物锰簇光组装. 化学进展[J]. 2010, 22(8): 1556-1565, http://lib.cqvip.com/Qikan/Article/Detail?id=34831349.
[32] Shuqin Li, Guiying Chen, Guangye Han, Deguang Huang, A A Khorobrykh, S K Zharmukhamedov, Lin Ling, Qiutian Li, V V Klimov, Tingyun Kuang. Coordination between manganese and nitrogen within the ligands in the manganese complexes facilitates the reconstitution of the Water-Oxidizing Complex in Manganese-depleted Photosystem II Preparation. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY[J]. 2006, 11(6): 783-790, http://ir.ibcas.ac.cn/handle/151111/2619.
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[34] 韩广业, 杨频. 异羟肟酸氧钒化合物的合成表征及配位化学性质研究. 分子科学学报：中英文版[J]. 2004, 20(2): 5-11, http://lib.cqvip.com/Qikan/Article/Detail?id=9910242.
[35] 韩广业, 李淑芹, 唐崇钦, 李良璧, 匡廷云. 光合放氧复合物结构及其放氧机理的研究. 化学进展[J]. 2004, 16(2): 184-195, http://lib.cqvip.com/Qikan/Article/Detail?id=9581242.