基本信息
王肇悦  女  硕导  中国科学院微生物研究所
电子邮件: wangzy@im.ac.cn
通信地址: 北京朝阳区北辰西路1号院3号
邮政编码:

招生信息

   
招生专业
071007-遗传学
招生方向
酵母菌分子遗传与生理代谢工程
酵母菌风味物质代谢与调控
食品级微生物表达系统构建

教育背景

2002-09--2005-06   浙江大学   博士

工作经历

   
工作简历
2013-09~2014-09,University of Massachusetts Dartmouth, 访问学者
2008-12~现在, 中国科学院微生物研究所, 副研究员
2007-05~2008-12,中国科学院微生物研究所, 助理研究员
2005-07~2007-05,中国科学院微生物研究所, 博士后
2002-09~2005-06,浙江大学, 博士

专利与奖励

   

出版信息

   
发表论文
(1) Reconstruction of metabolic module with improved promoter strength increases the productivity of 2-phenylethanol in Saccharomyces cerevisiae, Microbial Cell Factories, 2018, 第 1 作者
(2) Regulation of crucial enzymes and transcription factors on 2-phenylethanol biosynthesis via Ehrlich pathway in Saccharomyces cerevisiae, Journal of Industrial Microbiology and Biotechnology, 2017, 第 1 作者
(3) Regulation of general amino acid permeases Gap1p, GATA transcription factors Gln3p and Gat1p on 2-phenylethanol biosynthesis via Ehrlich pathway, Journal of Biotechnology, 2017, 第 11 作者
(4) 毕赤酵母中猪β-防御素的表达纯化鉴定及其在猪饲料行业的潜在应用研究, High-level expression, purification and characterization of porcine β-defensin 2 in Pichia pastoris and its potential as a cost-efficient growth promoter in porcine feed, Applied Microbiology and Biotechnology, 2014, 第 11 作者
(5) SOD1/GSH在啤酒酵母中协同过表达调节啤酒风味及抗老化能力, Secretion expression of SOD1 and its overlapping function with GSH in brewing yeast strain for better flavor and anti-aging ability, Journal of Industrial Microbiology and Biotechnology, 2014, 第 1 作者
(6) 淀粉酶/葡聚糖酶/谷胱甘肽合成酶基因整合表达的工业酿酒酵母菌株, Integrated expression of the α-amylase, dextranase and glutathione gene in an industrial brewer’s yeast strain, World Journal of Microbiology and Biotechnology, 2012, 第 11 作者
(7) 高甘油+谷胱甘肽的自克隆葡萄酒酵母菌株, Construction of self-cloning, indigenous wine strains of Saccharomyces cerevisiae with enhanced glycerol and glutathione production, Biotechnology Letters, 2012, 第 11 作者
(8) 具有淀粉分解能力的高谷胱甘肽酵母菌株改善啤酒抗老化及风味, Construction of an amylolytic industrial brewing yeast strain with high glutathione content to manufacture beer with improved anti-staling capability and flavor, Journal of Microbiology and Biotechnology, 2010, 第 11 作者
(9) 生产低热能及风味改良啤酒的工业酵母菌株, Construction of an industrial brewing yeast strain to manufacture beer with low caloric content and improved flavor, Journal of Microbiology and Biotechnology, 2010, 第 11 作者
(10) 工业酿酒酵母菌株中GAI表达及PEP4缺失研究, Expression of GAI gene and disruption of PEP4 gene in an industrial brewer’s yeast strain, Letters in Applied Microbiology, 2009, 第 1 作者
(11) 自克隆表达盒GSH1+CUP1阻断ADH2的重组工业酿酒酵母菌株, Recombinant industrial brewing yeast strains with ADH2 interruption by using self-cloning GSH1+CUP1 cassette,  FEMS Yeast Research, 2009, 第 1 作者
(12) ILV2缺失/LSD1表达的新型工业酵母菌株, New industrial brewing yeast strains with ILV2 disruption and LSD1 expression, International Journal of Food Microbiology, 2008, 第 1 作者
(13) 高谷胱甘肽低双乙酰自克隆工业酵母菌株的构建, Construction of self-cloning industrial brewing yeast with high-glutathione and low-diacetyl production., International Journal of Food Science and Technology, 2008, 第 1 作者
(14) 自克隆工业酵母菌中GSH1基因过表达及PEP4缺失, Over-expression of GSH1 gene and disruption of PEP4 gene in self-cloning industrial brewer?s yeast, International Journal of Food Microbiology, 2007, 第 1 作者
(15) 蛋白酶A缺失的工业酿酒酵母菌株构建, Construction of proteinase A deficient transformant of industrial brewing yeast,  European Food Research and Technology, 2007, 第 1 作者
(16) 鲜啤酒中酵母蛋白酶A的分离纯化及其对泡沫蛋白的特异性研究, Purification of yeast proteinase A from fresh beer and its specificity on foam proteins, International Journal of Food Science and Technology, 2005, 第 1 作者

科研活动

   
科研项目
( 1 ) 微生物高通量筛选及功能基因高效表达体系构建, 主持, 研究所(学校), 2011-04--2016-04
( 2 ) 酿酒酵母2-苯乙醇生物合成全局调控及其毒性机制研究, 主持, 国家级, 2012-01--2015-12
( 3 ) 酿酒酵母转录因子协同调控2-苯乙醇生物合成及其调控元件功能差异分析研究, 主持, 研究所(学校), 2016-01--2017-12
( 4 ) 基于Cat8p转录激活模体鉴定及其与酿酒酵母2-苯乙醇合成相关基因互作, 主持, 国家级, 2018-01--2021-12
参与会议
(1)Genetically incorporating fluorescent amino acids into proteins for molecular imaging in living cells    金属医学——无机化学在未来医学中的应用   Zhaoyue Wang, Zhiwei Liu, Bing Yan and Maolin Guo*    2014-06-22

合作情况