基本信息
罗雄剑  男  博导  中国科学院昆明动物研究所
电子邮件: luoxiongjian@mail.kiz.ac.cn
通信地址: 云南省昆明市校场东路32号(中科院昆明动物研究所)
邮政编码: 650223

招生信息

   
招生专业
071006-神经生物学
071007-遗传学
071008-发育生物学
招生方向
神经生物学
遗传学
发育生物学

教育背景

2005-09--2010-07   中国科学院昆明动物研究所   博士
2001-09--2005-07   武汉大学生命科学学院   理学学士

工作经历

   
工作简历
2014-09~现在, 中国科学院昆明动物研究所, 神经系统疾病学科组长、研究员
2010-09~2014-08,美国罗切斯特大学, 博士后
2005-09~2010-07,中国科学院昆明动物研究所, 博士
2001-09~2005-07,武汉大学生命科学学院, 理学学士

专利与奖励

   
奖励信息
(1) 中科院朱李月华优秀博士生奖, 一等奖, 其他, 2009

出版信息

   
发表论文
(1) Regulatory mechanisms of major depressive disorder risk variants, Molecular Psychiatry, 2020, 通讯作者
(2) A functional missense variant in ITIH3 affects protein expression and neurodevelopment and confers schizophrenia risk in Han Chinese population, Journal of Genetics and Genomics, 2020, 通讯作者
(3) Integration of GWAS and brain eQTL identifies FLOT1 as a risk gene for major depressive disorder, Neuropsychopharmacology, 2019, 通讯作者
(4) Identification of the primate-specific gene BTN3A2 as an additional schizophrenia risk gene in the MHC loci, EBioMedicine, 2019, 通讯作者
(5) The integrated landscape of causal genes and pathways in schizophrenia, Translational Psychiatry, 2018, 通讯作者
(6) Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes, Nature Communications, 2018, 通讯作者
(7) Systems-level analysis of risk genes reveals the modular nature of schizophrenia, Schizophrenia Research, 2018, 通讯作者
(8) Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder, Neuropsychopharmacology, 2018, 通讯作者
(9) SZDB: A Database for Schizophrenia Genetic Research, Schizophrenia Bulletin, 2017, 通讯作者
(10) Adaptive evolution of interleukin‑3 (IL3), a gene associated with brain volume variation in general populations, Human Genetics, 2016, 通讯作者
(11) No association between schizophrenia susceptibility variants and macroscopic structural brain volume variation in healthy subjects, Am J Med Genet Part B, 2016, 通讯作者
(12) Identification of SLC25A37 as a major depressive disorder risk gene, Journal of Psychiatric Research, 2016, 通讯作者
(13) Down-regulation of SIRT1 in major depressive disorder, The American Journal of Psychiatry, 2016, 通讯作者
(14) Common variants in the MKL1 gene confer risk of schizophrenia, Schizophrenia Bulletin, 2015, 通讯作者
(15) Systematic integration of brain eQTL and GWAS identifies ZNF323 as a novel schizophrenia risk gene and suggests recent positive selection based on compensatory advantage on pulmonary function, Schizophrenia Bulletin, 2015, 通讯作者
(16) Recent positive selection drives the expansion of a schizophrenia risk non-synonymous variant at SLC39A8 in Europeans, Schizophrenia Bulletin, 2015, 通讯作者
(17) Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance, British Journal of Psychiatry, 2015, 第 1 作者
(18) Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene, Molecular Psychiatry, 2014, 通讯作者
(19) Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function and bipolar disorder susceptibility, Molecular Psychiatry, 2014, 第 1 作者
(20) Protein-protein interaction and pathway analyses of top schizophrenia genes reveal schizophrenia susceptibility genes converge on common molecular networks and enrichment of nucleosome (chromatin) assembly genes in schizophrenia susceptibility loci, Schizophrenia Bulletin, 2014, 通讯作者
(21) Systematic Prioritization and Integrative Analysis of Copy Number Variations in Schizophrenia reveal key schizophrenia susceptibility genes, Schizophrenia Bulletin, 2014, 通讯作者
(22) LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea, The Journal of Neuroscience, 2014, 第 1 作者
(23) GATA3 controls the specification of prosensory domain and neuronal survival in the mouse cochlea, Human Molecular Genetics, 2013, 第 1 作者
(24) Protein-protein interaction analysis of schizophrenia susceptibility genes reveals common processes/pathways contributing to risk of schizophrenia, Schizophrenia Research, 2013, 通讯作者
(25) Further evidence for the association between the LSM1 gene and schizophreni, Schizophrenia Bulletin, 2013, 通讯作者
(26) The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors, PLoS ONE, 2012, 第 1 作者
(27) Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population, The World Journal of Biological Psychiatry, 2011, 第 1 作者
(28) Genetic association and identification of a functional SNP at GSK3β for schizophrenia susceptibility, Schizophrenia Research, 2011, 第 1 作者
(29) Allelic Differences Between Han Chinese and Europeans for Functional Variants in ZNF804A and Their Association With Schizophrenia, The American Journal of Psychiatry, 2011, 第 2 作者
(30) A common variant of the cardiomyopathy associated 5 gene (CMYA5) is associated with schizophrenia in Chinese population, Schizophrenia Research, 2011, 第 2 作者
(31) Association of haplotypes spanning PDZ-GEF2, LOC728637 and ACSL6 with schizophrenia in Han Chinese, Journal of Medical Genetics, 2008, 第 1 作者
(32) 

科研活动

   
科研项目
( 1 ) 中科院昆明动物研究所****启动项目, 主持, 市地级, 2014-09--2018-08
( 2 ) 中组部青年****, 主持, 国家级, 2015-09--2018-08
( 3 ) 中科院/云南省动物模型与人类疾病机理重点实验室, 主持, 市地级, 2015-05--2018-04
( 4 ) 移植后干细胞的在体示踪及功能分析的分子影像学研究, 主持, 国家级, 2016-07--2020-07
( 5 ) SLC39A8在精神分裂症发生中的遗传和分子机制, 主持, 省级, 2017-09--2020-09
( 6 ) 精神分裂症遗传机制及致病机理, 主持, 国家级, 2018-01--2020-12
( 7 ) 云南省神经精神疾病的遗传学研究及应用创新团队, 主持, 省级, 2019-01--2022-12
( 8 ) ITIH3在精神分裂症中的遗传机制和致病机理研究, 主持, 国家级, 2020-01--2023-12